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J. D. Del Valle · SciRah

Researcher profile · Semantic Scholar

J. D. Del Valle

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J. D. Del Valle — researcher profile on SciRah

h-index: 21
Works: 112
Citations: 2,010

Most-cited papers

Agonist-mediated activation of STING induces apoptosis in malignant B cells
C. Tang, Joseph A. Zundell, Sujeewa Ranatunga, Cindy Lin +3 more
2016Cancer Research278 citations Open access
Semantic Scholar
Chemistry and biology of the aeruginosin family of serine protease inhibitors.
Karolina Ersmark, J. D. Del Valle, S. Hanessian
2008Angewandte Chemie188 citations
Semantic Scholar
Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival.
C. Tang, Sujeewa Ranatunga, Crystina L. Kriss, C. Cubitt +4 more
2014Journal of Clinical Investigation171 citations Open access
Semantic Scholar
IRE1&agr; RNase–dependent lipid homeostasis promotes survival in Myc-transformed cancers
Hong Xie, C. Tang, Jun H Song, A. Mancuso +9 more
2018Journal of Clinical Investigation107 citations Open access
Semantic Scholar
Regulated Inositol-Requiring Enzyme 1 dependent mRNA decay sets the threshold for dendritic cell survival
S. Tavernier, F. Osorio, L. Vandersarren, Jessica Vetters +11 more
2017Nature Cell Biology99 citations Open access
Semantic Scholar
Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells
Lu Liu, Meiling Zhao, Xi Jin, Gina M. Ney +7 more
2019Nature Cell Biology93 citations Open access
Semantic Scholar
Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice.
Crystina L. Kriss, J. Pinilla-Ibarz, A. Mailloux, John J. Powers +8 more
2012Blood72 citations Open access
Semantic Scholar
Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization
C. Tang, Shiun Chang, A. Paton, J. Paton +4 more
2018Journal of Cell Biology57 citations Open access
Semantic Scholar
Peptide N-Amination Supports β-Sheet Conformations.
M. Sarnowski, Chang Won Kang, Yassin M. Elbatrawi, L. Wojtas +1 more
2017Angewandte Chemie42 citations
Semantic Scholar
Synthesis of novel tricyclic chromenone-based inhibitors of IRE-1 RNase activity
Sujeewa Ranatunga, C. Tang, Chang Won Kang, Crystina L. Kriss +3 more
2014Journal of Medicinal Chemistry39 citations Open access
Semantic Scholar
STING regulates BCR signaling in normal and malignant B cells
C. Tang, Avery C. Lee, Shiun Chang, Qin Xu +6 more
2020Cellular & Molecular Immunology35 citations Open access
Semantic Scholar
Structure-based organic synthesis of unnatural aeruginosin hybrids as potent inhibitors of thrombin.
S. Hanessian, Karolina Ersmark, Xiaotian Wang, J. D. Del Valle +3 more
2007Bioorganic & Medicinal Chemistry Letters30 citations Open access
Semantic Scholar
Secretory IgM exacerbates tumor progression by inducing accumulations of MDSCs in mice
C. Tang, Shiun Chang, Ayumi Hashimoto, Yi-Ju Chen +5 more
2018Cancer immunology research25 citations Open access
Semantic Scholar
Inhibition of the IRE-1α/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice.
Steven D. Schutt, Yongxia Wu, C. Tang, D. Bastian +10 more
2018Blood Advances24 citations Open access
Semantic Scholar
Total synthesis and structural revision of the presumed aeruginosins 205A and B.
S. Hanessian, Xiaotian Wang, Karolina Ersmark, J. D. Del Valle +1 more
2009Organic Letters23 citations Open access
Semantic Scholar
Access to Enantiopure α-Hydrazino Acids for N-Amino Peptide Synthesis.
Chang Won Kang, M. Sarnowski, Yassin M. Elbatrawi, J. D. Del Valle
2017Journal of Organic Chemistry22 citations
Semantic Scholar
Aeruginosine: Chemie und Biologie der Serinprotease-Inhibitoren
K. Ersmark, J. D. Del Valle, S. Hanessian
200821 citations
Semantic Scholar
Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity
B. Betts, F. Locke, Elizabeth M. Sagatys, J. Pidala +19 more
2018Frontiers in Immunology20 citations Open access
Semantic Scholar
Substituted Imidazo[1,2-a]pyridines as β-strand Peptidomimetics
Chang Won Kang, Yong-Ming Sun, J. D. Del Valle
2012Organic Letters20 citations Open access
Semantic Scholar
Invited Talks
J. D. Del Valle
2017Journal of Medical Physics19 citations
Semantic Scholar
Solid-Phase Synthesis of Tetrahydropyridazinedione-Constrained Peptides
Chang Won Kang, Sujeewa Ranatunga, M. Sarnowski, J. D. Del Valle
2014Organic Letters19 citations Open access
Semantic Scholar
Synthesis and β-sheet propensity of constrained N-amino peptides.
M. Sarnowski, Kyle P. Pedretty, Nicole Giddings, H. L. Woodcock +1 more
2017Bioorganic & Medicinal Chemistry17 citations Open access
Semantic Scholar
β-Strand mimics based on tetrahydropyridazinedione (tpd) peptide stitching
Chang Won Kang, M. Sarnowski, Sujeewa Ranatunga, L. Wojtas +3 more
2015Chemical Communications16 citations Open access
Semantic Scholar
Structure Assignment of Lucentamycin E and Revision of the Olefin Geometries of the Marine-Derived Lucentamycins
J. Cha, Jin-Soo Park, Taebo Sim, Sang-Uook Nam +3 more
2012Journal of Natural Products15 citations Open access
Semantic Scholar
Total synthesis of the putative structure of lucentamycin A.
Ujjwal Pal, Sujeewa Ranatunga, Yamuna Ariyarathna, J. D. Del Valle
2009Organic Letters15 citations Open access
Semantic Scholar
Beyond N-alkylation: Synthesis, structure, and function of N-aminopeptides
Isaac J Angera, Madison M. Wright, J. D. Del Valle
2024Accounts of Chemical Research14 citations
Semantic Scholar
Total Synthesis of L-156,373 and an oxoPiz Analogue via a Submonomer Approach.
Yassin M. Elbatrawi, Chang Won Kang, J. D. Del Valle
2018Organic Letters14 citations
Semantic Scholar
Imidazo[1,2-a]pyridine-based peptidomimetics as inhibitors of Akt
Young B. Kim, Chang Won Kang, Sujeewa Ranatunga, Hua Yang +2 more
2014Bioorganic & Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Synthesis of Boc-protected bicycloproline
Sujeewa Ranatunga, J. D. Del Valle
2009Tetrahedron Letters14 citations Open access
Semantic Scholar
Synthesis and biological evaluation of backbone-aminated analogues of gramicidin S.
Benjamin M. Rathman, Jessie L Allen, L. Shaw, J. D. Del Valle
2020Bioorganic & Medicinal Chemistry Letters13 citations
Semantic Scholar
Synthesis and conformational analysis of bicyclic extended dipeptide surrogates.
Sujeewa Ranatunga, Wathsala Liyanage, J. D. Del Valle
2010Journal of Organic Chemistry13 citations Open access
Semantic Scholar
Total Synthesis and Structural Revision of Lucentamycin A
Sujeewa Ranatunga, C. Tang, C. Hu, J. D. Del Valle
2012Journal of Organic Chemistry12 citations Open access
Semantic Scholar
An ester enolate-Claisen rearrangement route to substituted 4-alkylideneprolines. studies toward a definitive structural revision of lucentamycin A.
Sujeewa Ranatunga, Jinsoo Kim, Ujjwal Pal, J. D. Del Valle
2011Journal of Organic Chemistry11 citations
Semantic Scholar
Synthesis of GSK3β mimetic inhibitors of Akt featuring a novel extended dipeptide surrogate.
Sujeewa Ranatunga, J. D. Del Valle
2011Bioorganic & Medicinal Chemistry Letters11 citations Open access
Semantic Scholar
Synthesis of Carbapyochelins via Diastereoselective Azidation of 5-(Ethoxycarbonyl)methylproline Derivatives
Wathsala Liyanage, Laksiri Weerasinghe, R. Strong, J. D. Del Valle
2008Journal of Organic Chemistry11 citations Open access
Semantic Scholar
Development of tumor-targeting IRE-1 inhibitors for B cell cancer therapy
An-Dong Shao, Qin Xu, Walker T Spalek, Christopher F. Cain +4 more
2020Molecular Cancer Therapeutics10 citations Open access
Semantic Scholar
Structural tailoring of a novel fluorescent IRE-1 RNase inhibitor to precisely control its activity
An-Dong Shao, Chang Won Kang, C. Tang, Christopher F. Cain +4 more
2019Journal of Medicinal Chemistry10 citations Open access
Semantic Scholar
Macrocyclic β-arch peptides that mimic the structure and function of disease-associated tau folds
Isaac J Angera, Xue-Yong Xu, Benjamin H. Rajewski, G. Hallinan +5 more
2025Nature Chemistry9 citations Open access
Semantic Scholar
Intra-strand peptide staples that promote β-sheet folding, self-assembly, and amyloid seeding
Abha Dangi, Isaac J Angera, J. D. Del Valle
2025Journal of the American Chemical Society9 citations
Semantic Scholar
δ-Azaproline and its oxidized variants.
Yassin M. Elbatrawi, Kyle Pedretty, Nicole Giddings, H. Woodcock +1 more
2020Journal of Organic Chemistry9 citations
Semantic Scholar
IRE-1-Targeting Caged Prodrug with Endoplasmic Reticulum Stress-Inducing and XBP-1S-Inhibiting Activities for Cancer Therapy
An-Dong Shao, Qin Xu, Chang Won Kang, Christopher F. Cain +4 more
2022Molecular Pharmaceutics8 citations Open access
Semantic Scholar
N-Amination Converts Amyloidogenic Tau Peptides into Soluble Antagonists of Cellular Seeding
K. Makwana, M. Sarnowski, J. Miao, Yu-Shan Lin +1 more
2021ACS Chemical Neuroscience8 citations Open access
Semantic Scholar
Synthesis of Functionalized Octahydroindoles Related to Daphnyphyllum Alkaloids
Stéphane Dorich, J. D. Del Valle, S. Hanessian
2014Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry8 citations
Semantic Scholar
β-Bracelets: Macrocyclic cross-β epitope mimics based on a tau conformational strain
Benjamin H. Rajewski, K. Makwana, Isaac J Angera, Danielle K Geremia +6 more
2023Journal of the American Chemical Society7 citations
Semantic Scholar
Synthesis of enantiopure ε-oxapipecolic acid.
Evan H. Howard, Christopher F. Cain, Chang Won Kang, J. D. Del Valle
2020Journal of Organic Chemistry7 citations
Semantic Scholar
Blocking Tau Transmission by Biomimetic Graphene Nanoparticles
Runyao Zhu, K. Makwana, Youwen Zhang, Benjamin H. Rajewski +2 more
2023Journal of materials chemistry. B6 citations Open access
Semantic Scholar
Late-Stage Sidechain-to-Backbone Macrocyclization of N-Amino Peptides.
Benjamin M. Rathman, J. D. Del Valle
2022Organic Letters6 citations
Semantic Scholar
N-Amino peptide scanning reveals inhibitors of Aβ42 aggregation
Khalilia C Tillett, J. D. Del Valle
2020RSC Advances6 citations Open access
Semantic Scholar
Synthesis and evaluation of substituted hexahydronaphthalenes as novel inhibitors of the Mcl-1/BimBH3 interaction
Young B. Kim, M. Balasis, Kenichiro Doi, N. Berndt +6 more
2012Bioorganic & Medicinal Chemistry Letters6 citations Open access
Semantic Scholar
Synthesis of a diversifiable cis-dehydrodecalin scaffold based on meiogynin A
Young B. Kim, J. D. Del Valle
20116 citations
Semantic Scholar

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C. Hu×16
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C. Hu — researcher profile on SciRah
Chang Won Kang×15
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C. Tang×14
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Sujeewa Ranatunga×12
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M. Sarnowski — researcher profile on SciRah

S. Hanessian×4

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An-Dong Shao×4

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An-Dong Shao — researcher profile on SciRah

Isaac J Angera×4

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Isaac J Angera — researcher profile on SciRah

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Karolina Ersmark×3

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Karolina Ersmark — researcher profile on SciRah