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D. Bastian · SciRah

Researcher profile · Semantic Scholar

D. Bastian

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D. Bastian — researcher profile on SciRah

h-index: 21
Works: 54
Citations: 1,189

Most-cited papers

Metabolic reprogramming of alloantigen-activated T cells after hematopoietic cell transplantation.
Hung D. Nguyen, S. Chatterjee, K. Haarberg, Yongxia Wu +11 more
2016Journal of Clinical Investigation113 citations Open access
Semantic Scholar
Inhibition of BTK and ITK with Ibrutinib Is Effective in the Prevention of Chronic Graft-versus-Host Disease in Mice
Steven D. Schutt, Jia-Ning Fu, Hung D. Nguyen, D. Bastian +6 more
2015PLoS ONE85 citations Open access
Semantic Scholar
A single strain of Bacteroides fragilis protects gut integrity and reduces GVHD
M. Sofi, Yongxia Wu, Taylor Ticer, Steven D. Schutt +9 more
2021JCI Insight78 citations Open access
Semantic Scholar
Targeting Sirt-1 controls GVHD by inhibiting T-cell allo-response and promoting Treg stability in mice.
Anusara Daenthanasanmak, Supinya Iamsawat, Paramita Chakraborty, Hung D. Nguyen +4 more
2019Blood74 citations Open access
Semantic Scholar
MicroRNA-17-92 controls T-cell responses in graft-versus-host disease and leukemia relapse in mice.
Yongxia Wu, J. Heinrichs, D. Bastian, Jia-Ning Fu +8 more
2015Blood71 citations Open access
Semantic Scholar
Targeting JAK2 reduces GVHD and xenograft rejection through regulation of T cell differentiation
B. Betts, D. Bastian, Supinya Iamsawat, Hung D. Nguyen +16 more
2018Proceedings of the National Academy of Sciences of the United States of America63 citations Open access
Semantic Scholar
The IL-12 Cytokine and Receptor Family in Graft-vs.-Host Disease
D. Bastian, Yongxia Wu, B. Betts, Xue-Zhong Yu
2019Frontiers in Immunology62 citations Open access
Semantic Scholar
Ceramide synthesis regulates T cell activity and GVHD development.
M. Sofi, J. Heinrichs, M. Dany, Hung D. Nguyen +13 more
2017JCI Insight55 citations Open access
Semantic Scholar
MicroRNA-17-92 is required for T-cell and B-cell pathogenicity in chronic graft-versus-host disease in mice.
Yongxia Wu, Steven D. Schutt, Katelyn G. Paz, Mengmeng Zhang +9 more
2018Blood52 citations Open access
Semantic Scholar
CD8+ Tregs promote GVHD prevention and overcome the impaired GVL effect mediated by CD4+ Tregs in mice
J. Heinrichs, Jun Li, Hung D. Nguyen, Yongxia Wu +9 more
2016Oncoimmunology52 citations Open access
Semantic Scholar
T-bet is Critical for the Development of Acute Graft-versus-Host Disease through Controlling T-Cell Differentiation and Function
Jia-Ning Fu, Dapeng Wang, Yu Yu, J. Heinrichs +9 more
2014Journal of Immunology44 citations Open access
Semantic Scholar
Regulatory T-Cell Therapy for Graft-versus-host Disease
J. Heinrichs, D. Bastian, A. Veerapathran, C. Anasetti +2 more
2016Journal of immunology research and therapy36 citations
Semantic Scholar
Thioredoxin-1 confines T cell alloresponse and pathogenicity in graft-versus-host disease.
M. Sofi, Yongxia Wu, Steven D. Schutt, M. Dai +12 more
2019Journal of Clinical Investigation34 citations Open access
Semantic Scholar
PIM‐2 protein kinase negatively regulates T cell responses in transplantation and tumor immunity
Anusara Daenthanasanmak, Yongxia Wu, Supinya Iamsawat, Hung D. Nguyen +8 more
2018Journal of Clinical Investigation33 citations Open access
Semantic Scholar
T-Cell Metabolism in Hematopoietic Cell Transplantation
Hung D. Nguyen, Sandeepkumar Kuril, D. Bastian, Xue-Zhong Yu
2018Frontiers in Immunology32 citations Open access
Semantic Scholar
Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells.
Hung D. Nguyen, Sandeepkumar Kuril, D. Bastian, Jisun Kim +15 more
2018JCI Insight30 citations Open access
Semantic Scholar
Stabilization of Foxp3 Stability by Targeting JAK2 Enhances Efficacy of CD8 iTregs to Prevent Graft-versus-Host Disease
Supinya Iamsawat, Anusara Daenthanasanmak, J. H. Voss, Hung D. Nguyen +3 more
2018Journal of Immunology29 citations Open access
Semantic Scholar
Essential Role of Interleukin-12/23p40 in the Development of Graft-versus-Host Disease in Mice
Yongxia Wu, D. Bastian, Steven D. Schutt, Hung D. Nguyen +4 more
2015Biology of Blood and Marrow Transplantation29 citations Open access
Semantic Scholar
The druggable transcription factor Fli-1 regulates T cell immunity and tolerance in graft-versus-host disease
Steven D. Schutt, Yongxia Wu, A. Kharel, D. Bastian +11 more
2022Journal of Clinical Investigation25 citations Open access
Semantic Scholar
Vitamin C stabilizes CD8+ iTregs and enhances their therapeutic potential in controlling murine GVHD and leukemia relapse.
Supinya Iamsawat, Lin-Lu Tian, Anusara Daenthanasanmak, Yongxia Wu +3 more
2019Blood Advances24 citations Open access
Semantic Scholar
Inhibition of the IRE-1α/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice.
Steven D. Schutt, Yongxia Wu, C. Tang, D. Bastian +10 more
2018Blood Advances24 citations Open access
Semantic Scholar
Ceramide synthase 6 impacts T-cell allogeneic response and graft-versus-host disease through regulating N-RAS/ERK Pathway
M. Sofi, Lin-Lu Tian, Steven D. Schutt, Imran Khan +15 more
2022Leukemia20 citations Open access
Semantic Scholar
Inducible T-Cell Co-Stimulator Impacts Chronic Graft-Versus-Host Disease by Regulating Both Pathogenic and Regulatory T Cells
Mengmeng Zhang, Yongxia Wu, D. Bastian, Supinya Iamsawat +8 more
2018Frontiers in Immunology20 citations Open access
Semantic Scholar
MicroRNA-31 regulates T-cell metabolism via HIF1α and promotes chronic GVHD pathogenesis in mice
Yongxia Wu, Corey Mealer, Steven D. Schutt, Carole L. Wilson +12 more
2022Blood Advances19 citations Open access
Semantic Scholar
Interleukin‐23 receptor signaling by interleukin‐39 potentiates T cell pathogenicity in acute graft‐versus‐host disease
D. Bastian, Xiaohui Sui, Hung D. Nguyen, Yongxia Wu +7 more
2021American Journal of Transplantation12 citations Open access
Semantic Scholar
STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell function
Yongxia Wu, C. Tang, Corey Mealer, D. Bastian +11 more
2021Cellular & Molecular Immunology12 citations Open access
Semantic Scholar
Immune response to nucleic acid antigens and native DNA by human peripheral blood lymphocytes in vitro.
D. Bastian, H. Borel, Takeshi Sasaki, A. Steinberg +1 more
1985Journal of Immunology12 citations Open access
Semantic Scholar
Targeting the Complement Alternative Pathway Permits Graft Versus Leukemia Activity while Preventing Graft Versus Host Disease
Hung D. Nguyen, A. Alawieh, D. Bastian, Sandeepkumar Kuril +13 more
2020Clinical Cancer Research10 citations Open access
Semantic Scholar
A Possible New Therapy of Systemic Lupus Erythematosus (SLE) a
H. Borel, D. Bastian, B. Cooper, Y. Borel
1986Annals of the New York Academy of Sciences10 citations
Semantic Scholar
Lysosomal Acid Lipase Is Required for Donor T Cells to Induce Graft-versus-Host Disease
Hung D. Nguyen, Taylor Ticer, D. Bastian, Sandeepkumar Kuril +4 more
2020Cell Reports7 citations Open access
Semantic Scholar
IL-27 Receptor Signaling on T cells Augments GVHD Severity through Enhancing Th1 Responses
D. Bastian, Yue-Jun Liu, Yongxia Wu, Steven D. Schutt +6 more
2018Journal of immunology research and therapy7 citations
Semantic Scholar
Targeting JAK2 By Gene Knockout or Pacritinib Treatment Reduces Gvhd and Xenograft Rejection By Promoting Induced Treg Differentiation
B. Betts, D. Bastian, Hung D. Nguyen, J. Heinrichs +6 more
20155 citations
Semantic Scholar
Microrna-17-92 Cluster: Novel Target for Controlling Gvhd While Preserving GVL Effect
Yongxia Wu, D. Bastian, J. Heinrichs, Jia-Ning Fu +4 more
20144 citations
Semantic Scholar
Sting Negatively Regulates Allogeneic T-Cell Responses By Constraining Antigen-Presenting Cell Function
Yongxia Wu, C. Tang, Corey Mealer, D. Bastian +10 more
2020Blood2 citations Open access
Semantic Scholar
Fli-1 Regulates Multiple T-Cell Subsets during Inflammatory Responses and Experimental Graft-Versus-Host Disease
Steven D. Schutt, D. Bastian, Hee-Jin Choi, Yongxia Wu +4 more
2019Blood2 citations Open access
Semantic Scholar
Allogeneic T Cells Utilize Glycolysis As the Predominant Metabolic Pathway to Induce Acute Graft-Versus-Host Disease
Hung D. Nguyen, K. Haarberg, Yongxia Wu, Jia-Ning Fu +7 more
20142 citations
Semantic Scholar
Complement Promotes Gvhd through Suppressing Autophagy in Recipient Dendritic Cells after Allogeneic Hematopoietic Cell Transplantation in Mice
Hung D. Nguyen, D. Bastian, Sandeepkumar Kuril, M. Dany +5 more
20171 citations
Semantic Scholar
Oxidative Stress Regulates T Cell Pathogenicity in Gvhd
M. Sofi, Yongxia Wu, M. Dai, Steven D. Schutt +8 more
20171 citations
Semantic Scholar
Targeting Host Complement C3a/C5a Receptors to Control of Acute Graft-Versus-Host Disease in Mice
Hung D. Nguyen, J. Heinrichs, Jia-Ning Fu, Yongxia Wu +8 more
20151 citations
Semantic Scholar
The absence of IL-12Rβ2 expression on recipient non-hematopoietic cells diminishes acute graft-versus-host disease in the gastrointestinal tract
D. Bastian, Xiaohui Sui, Hee-Jin Choi, Yongxia Wu +5 more
2022Journal of Immunology0 citations Open access
Semantic Scholar
STING Negatively Regulates Allogeneic T Cell Responses by Constraining Function of Antigen Presenting Cells
Yongxia Wu, Corey Mealer, M. Sofi, Lin-Lu Tian +6 more
2020Journal of Immunology0 citations
Semantic Scholar
Potential Role of IL-39 in the Development of Gvhd
D. Bastian, Hung D. Nguyen, Yongxia Wu, Steven D. Schutt +4 more
2019Blood0 citations Open access
Semantic Scholar
Microrna-31 Regulates T-Cell Metabolism Via HIF1α and Promotes Effector Function
Yongxia Wu, Mengmeng Zhang, D. Bastian, M. Sofi +6 more
2019Blood0 citations Open access
Semantic Scholar
Association of Donor T Cell Repertoire in Host Lymphoid and Target Organs and Gvhd Development
Yongxia Wu, Jia-Ning Fu, Anusara Daenthanasanmak, Hung D. Nguyen +6 more
2018Blood0 citations
Semantic Scholar
2050 Identifying the role and immunobiological mechanisms of Fli-1 mediated pathogenicity in graft Versus host disease
Steven D. Schutt, Yongxia Wu, Anusara Daenthanasanmak, D. Bastian +7 more
2018Journal of Clinical and Translational Science0 citations Open access
Semantic Scholar
NKG2D Negatively Regulates CD4 T Cells in Allo-Response in Mice
Mengmeng Zhang, Yongxia Wu, D. Bastian, Hung D. Nguyen +4 more
20170 citations
Semantic Scholar
U Distinct Roles of IL-12Rβ1 and IL-23R in the Development of Acute and Chronic Gvhd
D. Bastian, Hung D. Nguyen, Yongxia Wu, Steven D. Schutt +5 more
20170 citations
Semantic Scholar
Microrna-31 Promotes T-Cell Pathogenicity in Chronic Graft-Versus-Host Disease
Yongxia Wu, Mengmeng Zhang, M. Sofi, Steven D. Schutt +3 more
20170 citations
Semantic Scholar
Prevention of Chronic Gvhd By Targeting Xbp-1 Genetically or Pharmacologically in Mice
Steven D. Schutt, C. Tang, Yongxia Wu, D. Bastian +3 more
20160 citations
Semantic Scholar
Inhibition of Alternative Complement Pathway in Target Organs Represents a Novel and Effective Approach to Control Gvhd While Sparing GVL Effect
Hung D. Nguyen, A. Alawieh, D. Bastian, Anusara Daenthanasanmak +6 more
20160 citations
Semantic Scholar

Frequent co-authors

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Xue-Zhong Yu×48
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Xue-Zhong Yu — researcher profile on SciRah
Yongxia Wu×42
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Yongxia Wu — researcher profile on SciRah
Hung D. Nguyen×37
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Hung D. Nguyen — researcher profile on SciRah
Steven D. Schutt×33
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Steven D. Schutt — researcher profile on SciRah

×22

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M. Sofi — researcher profile on SciRah

Anusara Daenthanasanmak×19

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Anusara Daenthanasanmak — researcher profile on SciRah

J. Heinrichs×16

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J. Heinrichs — researcher profile on SciRah

Mengmeng Zhang×15

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Mengmeng Zhang — researcher profile on SciRah

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Chen Liu — researcher profile on SciRah

Supinya Iamsawat×13

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Supinya Iamsawat — researcher profile on SciRah

Jia-Ning Fu×10

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Jia-Ning Fu — researcher profile on SciRah

Hee-Jin Choi×10

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Hee-Jin Choi — researcher profile on SciRah