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P. Doubleday · SciRah

Researcher profile · Semantic Scholar

P. Doubleday

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P. Doubleday — researcher profile on SciRah

h-index: 14
Works: 23
Citations: 675

Most-cited papers

Top-down characterization of endogenous protein complexes with native proteomics
O. Skinner, Nicole A. Haverland, L. Fornelli, R. Melani +7 more
2017Nature Chemical Biology139 citations Open access
Semantic Scholar
Quantitation and Identification of Thousands of Human Proteoforms below 30 kDa
Kenneth R. Durbin, L. Fornelli, Ryan T. Fellers, P. Doubleday +2 more
2016Journal of Proteome Research92 citations Open access
Semantic Scholar
Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk
I. Ntai, L. Fornelli, Caroline J. DeHart, Josiah E. Hutton +8 more
2018Proceedings of the National Academy of Sciences of the United States of America89 citations Open access
Semantic Scholar
Top-down proteomics: where we are, where we are going?
L. Fornelli, Timothy K. Toby, Luis F. Schachner, P. Doubleday +3 more
2017Journal of Proteomics54 citations Open access
Semantic Scholar
Extensive regulation of enzyme activity by phosphorylation in Escherichia coli
E. Schastnaya, Zrinka Raguz Nakic, Christoph H. Gruber, P. Doubleday +5 more
2021Nature Communications44 citations Open access
Semantic Scholar
Phosphoproteomics Reveals Resveratrol-Dependent Inhibition of Akt/mTORC1/S6K1 Signaling
A. Alayev, P. Doubleday, S. Berger, B. Ballif +1 more
2014Journal of Proteome Research40 citations Open access
Semantic Scholar
Thorough Performance Evaluation of 213 nm Ultraviolet Photodissociation for Top-down Proteomics*
L. Fornelli, K. Srzentič, Timothy K. Toby, P. Doubleday +14 more
2019Molecular & Cellular Proteomics31 citations Open access
Semantic Scholar
Non-enzymatic acetylation inhibits glycolytic enzymes in Escherichia coli.
E. Schastnaya, P. Doubleday, Luca Maurer, U. Sauer
2023Cell Reports26 citations Open access
Semantic Scholar
A Remarkable Difference That One Fluorine Atom Confers on the Mechanisms of Inactivation of Human Ornithine Aminotransferase by Two Cyclohexene Analogues of γ-Aminobutyric Acid
Wei Zhu, P. Doubleday, D. Catlin, P. Weerawarna +6 more
2020Journal of the American Chemical Society22 citations Open access
Semantic Scholar
Oncogenic KRAS creates an aspartate metabolism signature in colorectal cancer cells
P. Doubleday, L. Fornelli, I. Ntai, N. Kelleher
2021The FEBS Journal21 citations Open access
Semantic Scholar
Mechanism of Inactivation of Ornithine Aminotransferase by (1S,3S)-3-Amino-4-(hexafluoropropan-2-ylidenyl)cyclopentane-1-carboxylic Acid
M. Moschitto, P. Doubleday, D. Catlin, N. Kelleher +2 more
2019Journal of the American Chemical Society21 citations Open access
Semantic Scholar
Spectrum of Apolipoprotein AI and Apolipoprotein AII Proteoforms and Their Associations With Indices of Cardiometabolic Health: The CARDIA Study
J. Wilkins, H. Seckler, J. Rink, Philip D. Compton +8 more
2021Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease20 citations Open access
Semantic Scholar
Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over γ-Aminobutyric Acid Aminotransferase
Wei Zhu, A. Butrin, R. Melani, P. Doubleday +8 more
2022Journal of the American Chemical Society14 citations Open access
Semantic Scholar
Remarkable, Unexpected Mechanism for (S)-3-Amino-4-(Difluoromethylenyl)cyclohex-1-Ene-1-Carboxylic Acid as a Selective Inactivator of Human Ornithine Aminotransferase
Wei Zhu, P. Doubleday, A. Butrin, P. Weerawarna +6 more
2021Journal of the American Chemical Society14 citations Open access
Semantic Scholar
Elucidating Proteoform Dynamics Underlying the Senescence Associated Secretory Phenotype
P. Doubleday, L. Fornelli, N. Kelleher
2020Journal of Proteome Research13 citations Open access
Semantic Scholar
Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase
S. Shen, A. Butrin, P. Doubleday, R. Melani +7 more
2021Journal of the American Chemical Society12 citations Open access
Semantic Scholar
Mechanism-Based Design of 3-Amino-4-Halocyclopentenecarboxylic Acids as Inactivators of GABA Aminotransferase.
S. Shen, P. Doubleday, P. Weerawarna, Wei Zhu +2 more
2020ACS Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Developmentally-Dynamic Murine Brain Proteomes and Phosphoproteomes Revealed by Quantitative Proteomics
P. Doubleday, B. Ballif
2014Proteomes12 citations Open access
Semantic Scholar
Structural and Mechanistic Basis for the Inactivation of Human Ornithine Aminotransferase by (3S,4S)-3-Amino-4-fluorocyclopentenecarboxylic Acid
S. Shen, A. Butrin, B. Beaupre, G. M. Ferreira +7 more
2023Molecules1 citations Open access
Semantic Scholar
Dynamic metabolome profiling uncovers potential TOR signaling genes
Stella Reichling, P. Doubleday, Tomás Germade, A. Bergmann +3 more
2022bioRxiv1 citations Open access
Semantic Scholar
Native Proteomics: A New Approach to Protein Complex Discovery and Characterization
Philip D. Compton, O. Skinner, Nicole A. Haverland, L. Fornelli +4 more
20171 citations
Semantic Scholar
Correction to "Rational Design, Synthesis, and Mechanism of (3S,4R)-3-Amino-4-(difluoromethyl)cyclopent-1-ene-1-carboxylic Acid: Employing a Second-Deprotonation Strategy for Selectivity of Human Ornithine Aminotransferase over GABA Aminotransferase".
Wei Zhu, A. Butrin, R. Melani, P. Doubleday +8 more
2023Journal of the American Chemical Society0 citations Open access
Semantic Scholar
(1S,3S)-3-amino-4-(perfluoropropan-2-ylidene)cyclopentane-1-carboxylic acid hydrochloride, a potent inhibitor of ornithine aminotransferase
D. Catlin, Dali Liu, M. Moschitto, P. Doubleday +2 more
20190 citations
Semantic Scholar

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N. Kelleher×17
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N. Kelleher — researcher profile on SciRah
L. Fornelli×9
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