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C. Scarponi · SciRah

Researcher profile · Semantic Scholar

C. Scarponi

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C. Scarponi — researcher profile on SciRah

h-index: 31
Works: 67
Citations: 3,824

Most-cited papers

Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment
C. Albanesi, C. Scarponi, S. Pallotta, R. Daniele +9 more
2009Journal of Experimental Medicine346 citations Open access
Semantic Scholar
Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes.
C. Albanesi, C. Scarponi, A. Cavani, Monica Federici +2 more
2000Journal of Investigative Dermatology327 citations Open access
Semantic Scholar
IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response.
K. Eyerich, D. Pennino, C. Scarponi, S. Foerster +6 more
2009Journal of Allergy and Clinical Immunology246 citations Open access
Semantic Scholar
Keratinocytes in inflammatory skin diseases.
C. Albanesi, C. Scarponi, M. L. Giustizieri, G. Girolomoni
2005Current drug targets. Inflammation & allergy213 citations
Semantic Scholar
IL-4 and IL-13 Negatively Regulate TNF-α- and IFN-γ-Induced β-Defensin Expression through STAT-6, Suppressor of Cytokine Signaling (SOCS)-1, and SOCS-31
C. Albanesi, H. R. Fairchild, S. Madonna, C. Scarponi +3 more
2007Journal of Immunology179 citations Open access
Semantic Scholar
STAT3‐dependent effects of IL‐22 in human keratinocytes are counterregulated by sirtuin 1 through a direct inhibition of STAT3 acetylation
Rosanna Sestito, S. Madonna, C. Scarponi, F. Cianfarani +4 more
2011The FASEB Journal157 citations
Semantic Scholar
IL‐22 and TNF‐α represent a key cytokine combination for epidermal integrity during infection with Candida albicans
S. Eyerich, J. Wagener, Vera Wenzel, C. Scarponi +10 more
2011European Journal of Immunology146 citations Open access
Semantic Scholar
Impaired IFN-γ-Dependent Inflammatory Responses in Human Keratinocytes Overexpressing the Suppressor of Cytokine Signaling 11
Monica Federici, M. L. Giustizieri, C. Scarponi, G. Girolomoni +1 more
2002Journal of Immunology131 citations Open access
Semantic Scholar
IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment
L. Mercurio, Martina Morelli, C. Scarponi, E. Eisenmesser +9 more
2018Cell Death and Disease123 citations Open access
Semantic Scholar
Human neutrophils interact with both 6-sulfo LacNAc+ DC and NK cells to amplify NK-derived IFN{gamma}: role of CD18, ICAM-1, and ICAM-3.
C. Costantini, F. Calzetti, O. Perbellini, A. Micheletti +9 more
2011Blood122 citations Open access
Semantic Scholar
IL-17 Amplifies Human Contact Hypersensitivity by Licensing Hapten Nonspecific Th1 Cells to Kill Autologous Keratinocytes
D. Pennino, K. Eyerich, C. Scarponi, T. Carbone +6 more
2010Journal of Immunology119 citations Open access
Semantic Scholar
IL-4 Enhances Keratinocyte Expression of CXCR3 Agonistic Chemokines1
C. Albanesi, C. Scarponi, S. Sebastiani, A. Cavani +4 more
2000Journal of Immunology115 citations Open access
Semantic Scholar
IL-4 and IL-13 negatively regulate TNF-alpha- and IFN-gamma-induced beta-defensin expression through STAT-6, suppressor of cytokine signaling (SOCS)-1, and SOCS-3.
C. Albanesi, H. R. Fairchild, S. Madonna, C. Scarponi +3 more
2007Journal of Immunology113 citations
Semantic Scholar
A cytokine‐to‐chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases
C. Albanesi, C. Scarponi, S. Sebastiani, A. Cavani +3 more
2001Journal of Leukocyte Biology111 citations
Semantic Scholar
Interleukin‐17 and interleukin‐22 promote tumor progression in human nonmelanoma skin cancer
L. Nardinocchi, G. Sonego, F. Passarelli, S. Avitabile +5 more
2015European Journal of Immunology97 citations Open access
Semantic Scholar
Anti-apoptotic effects of suppressor of cytokine signaling 3 and 1 in psoriasis
S. Madonna, C. Scarponi, S. Pallotta, A. Cavani +1 more
2012Cell Death and Disease89 citations Open access
Semantic Scholar
Immune functions and recruitment of plasmacytoid dendritic cells in psoriasis
C. Albanesi, C. Scarponi, D. Bosisio, S. Sozzani +1 more
2010Autoimmunity88 citations
Semantic Scholar
Sirtinol Treatment Reduces Inflammation in Human Dermal Microvascular Endothelial Cells
A. Orecchia, C. Scarponi, F. Di Felice, E. Cesarini +8 more
2011PLoS ONE74 citations Open access
Semantic Scholar
Interleukin (IL)-17/IL-36 axis participates to the crosstalk between endothelial cells and keratinocytes during inflammatory skin responses
L. Mercurio, C. M. Failla, Lorena Capriotti, C. Scarponi +7 more
2019bioRxiv69 citations Open access
Semantic Scholar
The IFN-γ–Dependent Suppressor of Cytokine Signaling 1 Promoter Activity Is Positively Regulated by IFN Regulatory Factor-1 and Sp1 but Repressed by Growth Factor Independence-1b and Krüppel-Like Factor-4, and It Is Dysregulated in Psoriatic Keratinocytes
S. Madonna, C. Scarponi, Rosanna Sestito, S. Pallotta +2 more
2010Journal of Immunology62 citations
Semantic Scholar
Suppressor of cytokine signaling 1 inhibits IFN‐γ inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation
S. Madonna, C. Scarponi, O. de Pità, C. Albanesi
2008The FASEB Journal57 citations
Semantic Scholar
New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries.
N. Doti, P. Scognamiglio, S. Madonna, C. Scarponi +4 more
2012Biochemical Journal55 citations
Semantic Scholar
Therapeutical potential of a peptide mimicking the SOCS1 kinase inhibitory region in skin immune responses
S. Madonna, C. Scarponi, N. Doti, T. Carbone +4 more
2013European Journal of Immunology54 citations
Semantic Scholar
Nitric oxide donors suppress chemokine production by keratinocytes in vitro and in vivo.
M. L. Giustizieri, C. Albanesi, C. Scarponi, O. de Pità +1 more
2002American Journal of Pathology52 citations Open access
Semantic Scholar
Postglacial recolonization routes for Picea abies K. in Italy as suggested by the analysis of sequence‐characterized amplified region (SCAR) markers
I. Scotti, G. Vendramin, L. S. Matteotti, C. Scarponi +2 more
2000Molecular Ecology52 citations
Semantic Scholar
Knockout of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2
Rob van der Kammen, Ji-Ying Song, I. de Rink, H. Janssen +5 more
2017Development51 citations Open access
Semantic Scholar
Selective Immunomodulation of Inflammatory Pathways in Keratinocytes by the Janus Kinase (JAK) Inhibitor Tofacitinib: Implications for the Employment of JAK-Targeting Drugs in Psoriasis
Martina Morelli, C. Scarponi, L. Mercurio, F. Facchiano +4 more
2018Journal of Immunological Research50 citations Open access
Semantic Scholar
Inhibition of Inflammatory and Proliferative Responses of Human Keratinocytes Exposed to the Sesquiterpene Lactones Dehydrocostuslactone and Costunolide
C. Scarponi, Elena Butturini, Rosanna Sestito, S. Madonna +3 more
2014PLoS ONE48 citations Open access
Semantic Scholar
HLA-Cw6 and other HLA-C alleles, as well as MICB-DT, DDX58, and TYK2 genetic variants associate with optimal response to anti-IL-17A treatment in patients with psoriasis
Martina Morelli, M. Galluzzo, S. Madonna, C. Scarponi +8 more
2020Expert Opinion on Biological Therapy37 citations Open access
Semantic Scholar
Allergic Contact Dermatitis in Psoriasis Patients: Typical, Delayed, and Non-Interacting
M. Quaranta, S. Eyerich, Bettina Knapp, F. Nasorri +15 more
2014PLoS ONE37 citations Open access
Semantic Scholar
Paradoxical psoriasis induced by TNF‐α blockade shows immunological features typical of the early phase of psoriasis development
L. Fania, Martina Morelli, C. Scarponi, L. Mercurio +11 more
2019The Journal of Pathology: Clinical Research33 citations Open access
Semantic Scholar
RAS-activated PI3K/AKT signaling sustains cellular senescence via P53/P21 axis in experimental models of psoriasis.
L. Mercurio, Jacob Bailey, A. Glick, E. Dellambra +4 more
2024Journal of dermatological science (Amsterdam)31 citations Open access
Semantic Scholar
Intracellular Insulin-like growth factor binding protein 2 (IGFBP2) contributes to the senescence of keratinocytes in psoriasis by stabilizing cytoplasmic p21
L. Mercurio, D. Lulli, F. Mascia, E. Dellambra +9 more
2020Aging31 citations Open access
Semantic Scholar
Extracellular serine empowers epidermal proliferation and psoriasis-like symptoms
A. Cappello, M. Mancini, S. Madonna, S. Rinaldo +14 more
2022Science Advances28 citations Open access
Semantic Scholar
SOCS3 inhibits the pathological effects of IL-22 in non-melanoma skin tumor-derived keratinocytes
S. Madonna, C. Scarponi, Martina Morelli, Rosanna Sestito +3 more
2017OncoTarget27 citations Open access
Semantic Scholar
Enhanced NAMPT-Mediated NAD Salvage Pathway Contributes to Psoriasis Pathogenesis by Amplifying Epithelial Auto-Inflammatory Circuits
L. Mercurio, Martina Morelli, C. Scarponi, G. L. Scaglione +4 more
2021International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
Analysis of IFN-κ Expression in Pathologic Skin Conditions: Downregulation in Psoriasis and Atopic Dermatitis
C. Scarponi, B. Nardelli, David W. Lafleur, P. Moore +4 more
200623 citations
Semantic Scholar
PI3Kδ Sustains Keratinocyte Hyperproliferation and Epithelial Inflammation: Implications for a Topically Druggable Target in Psoriasis
L. Mercurio, Martina Morelli, C. Scarponi, G. L. Scaglione +3 more
2021Cells22 citations Open access
Semantic Scholar
The role of oncogenic Ras in human skin tumorigenesis depends on the clonogenic potential of the founding keratinocytes
R. Maurelli, Lavinia Tinaburri, F. Gangi, S. Bondanza +7 more
2016Journal of Cell Science21 citations Open access
Semantic Scholar
Low-Frequency Low-Intensity Ultrasounds Do Not Influence the Survival and Immune Functions of Cultured Keratinocytes and Dendritic Cells
C. Scarponi, F. Nasorri, F. Pavani, S. Madonna +5 more
2010Journal of Biomedicine and Biotechnology20 citations Open access
Semantic Scholar
IL-4 and IL-13 Negatively Regulate TNF--and IFN- -Induced -Defensin Expression through STAT-6, Suppressor of Cytokine Signaling (SOCS)-1, and SOCS-3
M. Howell, C. Scarponi, O. de Pità, D. Leung +3 more
200718 citations
Semantic Scholar
Leptin: a gender and obesity-related marker predictive of metabolic comorbidities and therapeutic response to anti-IL-23 biologic drugs in psoriatic patients
Roberta Belli, A. Dattolo, F. Sampogna, E. Gubinelli +18 more
2025Frontiers in Immunology17 citations Open access
Semantic Scholar
miR-200c inhibition and catalase accelerate diabetic wound healing
M. D'Agostino, S. Sileno, D. Lulli, N. de Luca +13 more
2025Journal of Biomedical Sciences16 citations Open access
Semantic Scholar
Analysis of IFN-kappa expression in pathologic skin conditions: downregulation in psoriasis and atopic dermatitis.
C. Scarponi, B. Nardelli, David W. Lafleur, P. Moore +4 more
2006Journal of Interferon and Cytokine Research14 citations
Semantic Scholar
Identification of immunological patterns characterizing immune-related psoriasis reactions in oncological patients in therapy with anti-PD-1 checkpoint inhibitors
Martina Morelli, M. Carbone, G. L. Scaglione, C. Scarponi +7 more
2024Frontiers in Immunology13 citations Open access
Semantic Scholar
Allelic Variants of HLA-C Upstream Region, PSORS1C3, MICA, TNFA and Genes Involved in Epidermal Homeostasis and Barrier Function Influence the Clinical Response to Anti-IL-12/IL-23 Treatment of Patients with Psoriasis
Martina Morelli, M. Galluzzo, C. Scarponi, S. Madonna +5 more
2022Vaccines13 citations Open access
Semantic Scholar
Correction: Sirtinol Treatment Reduces Inflammation in Human Dermal Microvascular Endothelial Cells
A. Orecchia, C. Scarponi, F. Di Felice, E. Cesarini +8 more
2011PLoS ONE13 citations Open access
Semantic Scholar
Platelet lysate promotes the expansion of T regulatory cells that favours in vitro wound healing by increasing keratinocyte migration and fibroblast production of extracellular matrix components
F. Scopelliti, Caterina Cattani, Valentina Di Martino, C. Scarponi +5 more
2020EJD. European journal of dermatology10 citations Open access
Semantic Scholar
Eosin treatment for psoriasis reduces skin leukocyte infiltration and secretion of inflammatory chemokines and angiogenic factors
Lorena Capriotti, B. Didona, S. Madonna, C. Scarponi +5 more
2018EJD. European journal of dermatology9 citations
Semantic Scholar
Experimental Methods for the Immunological Characterization of Paradoxical Psoriasis Reactions Induced by TNF-α Biologics.
Martina Morelli, C. Scarponi, S. Madonna, C. Albanesi
2021Methods in molecular biology8 citations
Semantic Scholar

Frequent co-authors

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C. Albanesi×46
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C. Albanesi — researcher profile on SciRah
S. Madonna×32
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S. Madonna — researcher profile on SciRah
A. Cavani×18
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A. Cavani — researcher profile on SciRah
G. Girolomoni×14
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G. Girolomoni — researcher profile on SciRah

×12

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S. Pallotta — researcher profile on SciRah

Martina Morelli×12

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Martina Morelli — researcher profile on SciRah

O. de Pità×10

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O. de Pità — researcher profile on SciRah

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L. Mercurio — researcher profile on SciRah

C. M. Failla×7

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C. M. Failla — researcher profile on SciRah

G. L. Scaglione×6

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G. L. Scaglione — researcher profile on SciRah

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F. Nasorri — researcher profile on SciRah

Rosanna Sestito×5

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Rosanna Sestito — researcher profile on SciRah