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C. Costantini · SciRah

Researcher profile · Semantic Scholar

C. Costantini

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C. Costantini — researcher profile on SciRah

h-index: 30
Works: 94
Citations: 6,299

Most-cited papers

Neutrophils in the activation and regulation of innate and adaptive immunity
A. Mantovani, M. Cassatella, C. Costantini, S. Jaillon
2011Nature reviews. Immunology2,978 citations
Semantic Scholar
Evidence for a cross-talk between human neutrophils and Th17 cells.
Martin Pelletier, L. Maggi, A. Micheletti, E. Lazzeri +7 more
2010Blood808 citations Open access
Semantic Scholar
A TrkA-to-p75NTR molecular switch activates amyloid beta-peptide generation during aging.
C. Costantini, R. Weindruch, G. della Valle, L. Puglielli
2005Biochemical Journal148 citations Open access
Semantic Scholar
The defensive alliance between neutrophils and NK cells as a novel arm of innate immunity
C. Costantini, M. Cassatella
2011Journal of Leukocyte Biology147 citations Open access
Semantic Scholar
An aging pathway controls the TrkA to p75NTR receptor switch and amyloid β‐peptide generation
C. Costantini, H. Scrable, L. Puglielli
2006EMBO Journal132 citations Open access
Semantic Scholar
Neutrophil activation and survival are modulated by interaction with NK cells.
C. Costantini, A. Micheletti, F. Calzetti, O. Perbellini +2 more
2010International Immunology130 citations
Semantic Scholar
Human neutrophils interact with both 6-sulfo LacNAc+ DC and NK cells to amplify NK-derived IFN{gamma}: role of CD18, ICAM-1, and ICAM-3.
C. Costantini, F. Calzetti, O. Perbellini, A. Micheletti +9 more
2011Blood122 citations Open access
Semantic Scholar
A reversible form of lysine acetylation in the ER and Golgi lumen controls the molecular stabilization of BACE1.
C. Costantini, Mi-Hee Ko, Mary Cabell Jonas, L. Puglielli
2007Biochemical Journal122 citations Open access
Semantic Scholar
PCSK9 is required for the disposal of non‐acetylated intermediates of the nascent membrane protein BACE1
Mary Cabell Jonas, C. Costantini, L. Puglielli
2008EMBO Reports121 citations Open access
Semantic Scholar
Neurotrophin p75 Receptor Is Involved in Neuronal Damage by Prion Peptide-(106–126)*
V. Della-Bianca, F. Rossi, U. Armato, Ilaria Dal-Pra +4 more
2001Journal of Biological Chemistry90 citations Open access
Semantic Scholar
Epigenetic Mechanisms of Inflammasome Regulation
Giulia Poli, Consuelo Fabi, M. Bellet, C. Costantini +3 more
2020International Journal of Molecular Sciences72 citations Open access
Semantic Scholar
Characterization of the signaling pathway downstream p75 neurotrophin receptor involved in β-amyloid peptide-dependent cell death
C. Costantini, F. Rossi, E. Formaggio, R. Bernardoni +2 more
2007Journal of Molecular Neuroscience72 citations
Semantic Scholar
IL-9 and Mast Cells Are Key Players of Candida albicans Commensalism and Pathogenesis in the Gut
G. Renga, S. Moretti, Vasilis Oikonomou, M. Borghi +15 more
2018Cell Reports65 citations Open access
Semantic Scholar
A Reappraisal of Thymosin Alpha1 in Cancer Therapy
C. Costantini, M. Bellet, M. Pariano, G. Renga +4 more
2019Frontiers in Oncology63 citations Open access
Semantic Scholar
Targeting the Aryl Hydrocarbon Receptor With Indole-3-Aldehyde Protects From Vulvovaginal Candidiasis via the IL-22-IL-18 Cross-Talk
M. Borghi, M. Pariano, Valentina Solito, M. Puccetti +9 more
2019Frontiers in Immunology61 citations Open access
Semantic Scholar
Indole-3-Carboxaldehyde Restores Gut Mucosal Integrity and Protects from Liver Fibrosis in Murine Sclerosing Cholangitis
F. D'Onofrio, G. Renga, M. Puccetti, M. Pariano +8 more
2021Cells58 citations Open access
Semantic Scholar
The IL-17F/IL-17RC Axis Promotes Respiratory Allergy in the Proximal Airways.
A. De Luca, M. Pariano, B. Cellini, C. Costantini +9 more
2017Cell Reports51 citations Open access
Semantic Scholar
Relationship between testicular sperm extraction and varicocelectomy in patients with varicocele and nonobstructive azoospermia.
N. Zampieri, L. Bosaro, C. Costantini, S. Zaffagnini +1 more
2013Urology48 citations
Semantic Scholar
Pyridoxal 5′-Phosphate-Dependent Enzymes at the Crossroads of Host–Microbe Tryptophan Metabolism
B. Cellini, T. Zelante, Mirco Dindo, M. Bellet +3 more
2020International Journal of Molecular Sciences47 citations Open access
Semantic Scholar
The Microbiota/Host Immune System Interaction in the Nose to Protect from COVID-19
A. di Stadio, C. Costantini, G. Renga, M. Pariano +2 more
2020Life46 citations Open access
Semantic Scholar
IFN-β Expression Is Directly Activated in Human Neutrophils Transfected with Plasmid DNA and Is Further Increased via TLR-4–Mediated Signaling
NICOLA TAMASSIA, F. Bazzoni, V. Le Moigne, F. Calzetti +8 more
2012Journal of Immunology42 citations Open access
Semantic Scholar
ACTH receptor mRNA in human adrenocortical tumors: overexpression in aldosteronomas.
Giorgio Arnaldi, V. Mancini, C. Costantini, M. Giovagnetti +4 more
1998Endocrine Research41 citations
Semantic Scholar
slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells
W. Vermi, A. Micheletti, S. Lonardi, C. Costantini +8 more
2014Nature Communications40 citations Open access
Semantic Scholar
Enteric formulated indole-3-carboxaldehyde targets the aryl hydrocarbon receptor for protection in a murine model of metabolic syndrome.
M. Puccetti, M. Pariano, M. Borghi, C. Barola +6 more
2021International journal of pharmaceutics39 citations
Semantic Scholar
The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of beta-amyloid.
C. Costantini, V. Della-Bianca, E. Formaggio, C. Chiamulera +2 more
2005Experimental Cell Research37 citations
Semantic Scholar
Tryptophan Co-Metabolism at the Host-Pathogen Interface
C. Costantini, M. Bellet, G. Renga, C. Stincardini +6 more
2020Frontiers in Immunology35 citations Open access
Semantic Scholar
Covid-19-Associated Pulmonary Aspergillosis: The Other Side of the Coin
C. Costantini, F. L. van de Veerdonk, L. Romani
2020Vaccines35 citations Open access
Semantic Scholar
Ceramide and Cholesterol: Possible Connections Between Normal Aging of the Brain and Alzheimer's Disease. Just hypotheses or molecular pathways to be identified?
C. Costantini, Rekha M. K. Kolasani, L. Puglielli
2005Alzheimer's & Dementia32 citations
Semantic Scholar
Microbes in the Era of Circadian Medicine
C. Costantini, G. Renga, Federica Sellitto, M. Borghi +9 more
2020Frontiers in Cellular and Infection Microbiology31 citations Open access
Semantic Scholar
A new oxidation pathway of the neurotoxin 6-aminodopamine. Isolation and characterisation of a dimer with a tetrahydro[3,4a]iminoethanophenoxazine ring system.
A. Napolitano, M. d’Ischia, C. Costantini, G. Prota
199230 citations
Semantic Scholar
Thymosin β4 limits inflammation through autophagy
G. Renga, Vasilis Oikonomou, C. Stincardini, M. Pariano +6 more
2018Expert Opinion on Biological Therapy29 citations
Semantic Scholar
The Circadian Protein PER1 Modulates the Cellular Response to Anticancer Treatments
M. Bellet, C. Stincardini, C. Costantini, M. Gargaro +7 more
2021International Journal of Molecular Sciences28 citations Open access
Semantic Scholar
Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity
M. Pariano, Stefania Pieroni, A. De Luca, R. Iannitti +12 more
2021International Journal of Molecular Sciences27 citations Open access
Semantic Scholar
Thymosin α1 protects from CTLA-4 intestinal immunopathology
G. Renga, M. Bellet, M. Pariano, M. Gargaro +9 more
2020Life Science Alliance26 citations Open access
Semantic Scholar
Characterisation of 1,4-benzothiazine intermediates in the oxidative conversion of 5-S-cysteinyldopa to pheomelanins
A. Napolitano, C. Costantini, O. Crescenzi, G. Prota
199425 citations
Semantic Scholar
Tryptophan as a Central Hub for Host/Microbial Symbiosis
M. Borghi, M. Puccetti, M. Pariano, G. Renga +5 more
2020International Journal of Tryptophan Research24 citations Open access
Semantic Scholar
Autophagy and LAP in the Fight against Fungal Infections: Regulation and Therapeutics
Vasileios Oikonomou, G. Renga, A. De Luca, M. Borghi +8 more
2018Mediators of Inflammation24 citations Open access
Semantic Scholar
On the potential involvement of CD11d in co-stimulating the production of interferon-γ by natural killer cells upon interaction with neutrophils via intercellular adhesion molecule-3
C. Costantini, A. Micheletti, F. Calzetti, O. Perbellini +4 more
2011Haematologica24 citations Open access
Semantic Scholar
Targeted Drug Delivery Technologies Potentiate the Overall Therapeutic Efficacy of an Indole Derivative in a Mouse Cystic Fibrosis Setting
M. Puccetti, M. Pariano, G. Renga, I. Santarelli +8 more
2021Cells23 citations Open access
Semantic Scholar
Anti-Müllerian hormone and antral follicle count reveal a late impairment of ovarian reserve in patients undergoing low-gonadotoxic regimens for hematological malignancies.
R. Di Paola, C. Costantini, C. Tecchio, G. Salvagno +5 more
2013The Oncologist20 citations Open access
Semantic Scholar
Development and in vitro-in vivo performances of an inhalable indole-3-carboxaldehyde dry powder to target pulmonary inflammation and infection.
M. Puccetti, Larissa Gomes dos Reis, M. Pariano, C. Costantini +4 more
2021International journal of pharmaceutics18 citations
Semantic Scholar
Genetic Polymorphisms Affecting IDO1 or IDO2 Activity Differently Associate With Aspergillosis in Humans
V. Napolioni, M. Pariano, M. Borghi, Vasilis Oikonomou +21 more
2019Frontiers in Immunology18 citations Open access
Semantic Scholar
Thymosin β4 promotes autophagy and repair via HIF-1α stabilization in chronic granulomatous disease
G. Renga, Vasilis Oikonomou, S. Moretti, C. Stincardini +11 more
2019Life Science Alliance17 citations Open access
Semantic Scholar
Role of growth factors in the human endometrium during aging.
M. Leone, C. Costantini, G. Gallo, A. Voci +3 more
1993Maturitas17 citations
Semantic Scholar
New intermediates of phaeomelanogenesis in vitro beyond the 1,4-benzothiazine stage
C. Costantini, O. Crescenzi, G. Prota, A. Palumbo
199016 citations
Semantic Scholar
IL-9 Integrates the Host-Candida Cross-Talk in Vulvovaginal Candidiasis to Balance Inflammation and Tolerance
G. Renga, M. Borghi, V. Oikonomou, P. Mosci +4 more
2018Frontiers in Immunology15 citations Open access
Semantic Scholar
Astrocytes Regulate the Expression of Insulin-Like Growth Factor 1 Receptor (IGF1-R) in Primary Cortical Neurons During In Vitro Senescence
C. Costantini, E. Lorenzetto, B. Cellini, M. Buffelli +2 more
2010Journal of Molecular Neuroscience15 citations
Semantic Scholar
Pharyngeal Microbial Signatures Are Predictive of the Risk of Fungal Pneumonia in Hematologic Patients
C. Costantini, E. Nunzi, Angelica Spolzino, M. Palmieri +26 more
2021Infection and Immunity14 citations Open access
Semantic Scholar
The ILE56 mutation on different genetic backgrounds of alanine: Glyoxylate aminotransferase: Clinical features and biochemical characterization.
Mirco Dindo, G. Mandrile, C. Conter, R. Montone +4 more
2020Molecular Genetics and Metabolism14 citations Open access
Semantic Scholar
To Be or Not to Be a Pathogen: Candida albicans and Celiac Disease
G. Renga, M. Bellet, C. Stincardini, M. Pariano +6 more
2019Frontiers in Immunology14 citations Open access
Semantic Scholar

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