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E. Payen · SciRah

Researcher profile · Semantic Scholar

E. Payen

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E. Payen — researcher profile on SciRah

h-index: 26
Works: 64
Citations: 6,221

Most-cited papers

Hematopoietic Stem Cell Gene Therapy with a Lentiviral Vector in X-Linked Adrenoleukodystrophy
N. Cartier, S. Hacein-Bey-Abina, C. Bartholomae, G. Veres +22 more
2009Science1,469 citations Open access
Semantic Scholar
Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia
M. Cavazzana-Calvo, E. Payen, O. Nègre, Gary Wang +34 more
2010Nature1,321 citations Open access
Semantic Scholar
Gene Therapy in Patients with Transfusion‐Dependent β‐Thalassemia
A. Thompson, M. Walters, J. Kwiatkowski, J. Rasko +43 more
2018New England Journal of Medicine588 citations Open access
Semantic Scholar
Correction of Sickle Cell Disease in Transgenic Mouse Models by Gene Therapy
R. Pawliuk, K. Westerman, M. Fabry, E. Payen +10 more
2001Science568 citations
Semantic Scholar
Gene Therapy in a Patient with Sickle Cell Disease: Brief Report
J. Ribeil, S. Hacein-Bey-Abina, E. Payen, A. Magnani +23 more
2017New England Journal of Medicine396 citations Open access
Semantic Scholar
An activin receptor IIA ligand trap corrects ineffective erythropoiesis in β-thalassemia
Michael Dussiot, T. Maciel, A. Fricot, C. Chartier +17 more
2014Nature Medicine296 citations Open access
Semantic Scholar
Permanent and panerythroid correction of murine β thalassemia by multiple lentiviral integration in hematopoietic stem cells
S. Imren, E. Payen, K. Westerman, R. Pawliuk +11 more
2002Proceedings of the National Academy of Sciences of the United States of America192 citations Open access
Semantic Scholar
Gene Therapy of the β-Hemoglobinopathies by Lentiviral Transfer of the βA(T87Q)-Globin Gene
O. Nègre, Anne-Virginie Eggimann, Y. Beuzard, J. Ribeil +7 more
2016Human Gene Therapy149 citations Open access
Semantic Scholar
Preclinical Evaluation of Efficacy and Safety of an Improved Lentiviral Vector for the Treatment of β-Thalassemia and Sickle Cell Disease
O. Nègre, C. Bartholomae, Y. Beuzard, M. Cavazzana +20 more
2014Current Gene Therapy117 citations Open access
Semantic Scholar
Long-term outcomes of lentiviral gene therapy for the β-hemoglobinopathies: the HGB-205 trial
E. Magrin, M. Semeraro, N. Hebert, L. Joseph +39 more
2022Nature Medicine97 citations
Semantic Scholar
Current and future alternative therapies for beta-thalassemia major
Edouard De Dreuzy, Kanit Bhukhai, P. Leboulch, E. Payen
2016Biomedical Journal83 citations Open access
Semantic Scholar
Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia.
Keshet Ronen, O. Nègre, S. Roth, Charlotte Colomb +11 more
2011Molecular Therapy75 citations Open access
Semantic Scholar
Highly efficient in vitro and in vivo delivery of functional RNAs using new versatile MS2-chimeric retrovirus-like particles
Anne Prel, V. Caval, R. Gayon, P. Ravassard +14 more
2015Molecular Therapy: Methods & Clinical Development69 citations Open access
Semantic Scholar
Dimeric erythropoietin fusion protein with enhanced erythropoietic activity in vitro and in vivo.
B. Dalle, A. Henri, P. Rouyer-Fessard, M. Bettan +3 more
2001Blood56 citations Open access
Semantic Scholar
Improvement of mouse β-thalassemia by electrotransfer of erythropoietin cDNA
E. Payen, M. Bettan, P. Rouyer-Fessard, Y. Beuzard +1 more
200154 citations Open access
Semantic Scholar
Improvement of mouse β-thalassemia upon erythropoietin delivery by encapsulated myoblasts
Bruno Dalle, E. Payen, Etienne Régulier, N. Déglon +3 more
1999Gene Therapy54 citations Open access
Semantic Scholar
Advances in stem cell transplantation and gene therapy in the β-hemoglobinopathies.
E. Payen, P. Leboulch
2012Hematology. American Society of Hematology. Education Program49 citations Open access
Semantic Scholar
Is normal hematopoiesis maintained solely by long-term multipotent stem cells?
M. Cavazzana-Calvo, A. Fischer, F. Bushman, E. Payen +2 more
2011Blood41 citations Open access
Semantic Scholar
High-Efficiency Transduction of Primary Human Hematopoietic Stem/Progenitor Cells by AAV6 Vectors: Strategies for Overcoming Donor-Variation and Implications in Genome Editing
Chen Ling, Kanit Bhukhai, Zifei Yin, M. Tan +4 more
2016Scientific Reports40 citations Open access
Semantic Scholar
Long-term doxycycline-regulated secretion of erythropoietin by encapsulated myoblasts.
B. Sommer, Christopher Rinsch, E. Payen, B. Dalle +5 more
2002Molecular Therapy39 citations Open access
Semantic Scholar
Hemoglobin disorders: lentiviral gene therapy in the starting blocks to enter clinical practice.
K. Sii-Felice, M. Giorgi, P. Leboulch, E. Payen
2018Experimental Hematology37 citations Open access
Semantic Scholar
Oxygen tension and a pharmacological switch in the regulation of transgene expression for gene therapy
E. Payen, M. Bettan, A. Henri, E. Tomkiewitcz +5 more
2001Journal of Gene Medicine37 citations Open access
Semantic Scholar
Outcomes of Gene Therapy for Severe Sickle Disease and Beta-Thalassemia Major Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral Beta AT87Q-Globin Vector
M. Cavazzana, J. Ribeil, E. Payen, F. Suarez +19 more
201534 citations
Semantic Scholar
Protective effects of phosphodiesterase‐4 (PDE‐4) inhibition in the early phase of pulmonary arterial hypertension in transgenic sickle cell mice
L. De Franceschi, O. Platt, G. Malpeli, A. Janin +5 more
2008The FASEB Journal33 citations
Semantic Scholar
Improvement of mouse beta-thalassemia by electrotransfer of erythropoietin cDNA.
E. Payen, M. Bettan, P. Rouyer-Fessard, Y. Beuzard +1 more
2001Experimental Hematology33 citations Open access
Semantic Scholar
Therapy of Anemia in Kidney Failure, Using Plasmid Encoding Erythropoietin
P. Richard-Fiardo, E. Payen, R. Chèvre, J. Zuber +3 more
2008Human Gene Therapy32 citations
Semantic Scholar
Parallel assessment of globin lentiviral transfer in induced pluripotent stem cells and adult hematopoietic stem cells derived from the same transplanted β‐thalassemia patient
Alisa Tubsuwan, Soumeya Abed, A. Deichmann, Melanie D. Kardel +12 more
2013Stem Cells29 citations Open access
Semantic Scholar
Arrayed lentiviral barcoding for quantification analysis of hematopoietic dynamics
J. Grosselin, K. Sii-Felice, E. Payen, S. Chrétien +2 more
2013Stem Cells25 citations
Semantic Scholar
Correction of murine β-thalassemia after minimal lentiviral gene transfer and homeostatic in vivo erythroid expansion.
O. Nègre, F. Fusil, Charlotte Colomb, Shoshannah L. Roth +6 more
2011Blood25 citations Open access
Semantic Scholar
Transcription of Y‐ and X‐linked genes in preimplantation ovine embryos
M. Bernardi, C. Cotinot, E. Payen, C. Delouis
1996Molecular Reproduction and Development23 citations
Semantic Scholar
Ex Vivo Selection of Transduced Hematopoietic Stem Cells for Gene Therapy of β-Hemoglobinopathies
Kanit Bhukhai, Edouard De Dreuzy, M. Giorgi, Charlotte Colomb +12 more
2017Molecular Therapy19 citations Open access
Semantic Scholar
Lentivirus vectors in β-thalassemia.
E. Payen, Charlotte Colomb, O. Nègre, Y. Beuzard +2 more
2012Methods in Enzymology16 citations
Semantic Scholar
Modulation of transduced erythropoietin expression by iron.
Bruno Dalle, E. Payen, Yves Beuzard
2000Experimental Hematology15 citations Open access
Semantic Scholar
Sequence evolution of SRY gene within Bovidae family
E. Payen, C. Cotinot
1994Mammalian Genome15 citations
Semantic Scholar
Coordinated β-globin expression and α2-globin reduction in a multiplex lentiviral gene therapy vector for β-thalassemia
T. Nualkaew, K. Sii-Felice, M. Giorgi, B. McColl +11 more
2021Molecular Therapy14 citations Open access
Semantic Scholar
Study Hgb-205: Outcomes of Gene Therapy for Hemoglobinopathies Via Transplantation of Autologous Hematopoietic Stem Cells Transduced Ex Vivo with a Lentiviral βΑ-T87Q-Globin Vector (LentiGlobin® BB305 Drug Product)
M. Cavazzana, J. Ribeil, E. Payen, F. Suarez +18 more
201413 citations
Semantic Scholar
Gene Therapy in a Patient with Sickle Cell Disease.
J. Ribeil, S. Hacein-Bey-Abina, E. Payen, A. Magnani +23 more
2017New England Journal of Medicine12 citations
Semantic Scholar
Transplantation of Macaca cynomolgus iPS-derived hematopoietic cells in NSG immunodeficient mice
Soumeya Abed, Alisa Tubsuwan, Porntip Chaichompoo, In-Hyun Park +15 more
2015Haematologica12 citations Open access
Semantic Scholar
Genetic Vaccines and Therapy
Emmanuelle E. Fabre, P. Bigey, Y. Beuzard, D. Scherman +1 more
200811 citations
Semantic Scholar
Innovative Therapies for Hemoglobin Disorders
K. Sii-Felice, O. Nègre, C. Brendel, Alisa Tubsuwan +3 more
2020BioDrugs9 citations
Semantic Scholar
Longer Term Follow-up on the First Patients with Severe Hemoglobinopathies Treated with Lentiglobin Gene Therapy
M. Cavazzana, S. Hacein-Bey-Abina, E. Payen, E. Magrin +26 more
20178 citations
Semantic Scholar
279. Clinical Outcomes of Gene Therapy with BB305 Lentiviral Vector for Sickle Cell Disease and β-Thalassemia
M. Cavazzana, J. Ribeil, E. Payen, F. Touzot +21 more
20167 citations Open access
Semantic Scholar
Update from the Hgb-205 Phase 1/2 Clinical Study of Lentiglobin Gene Therapy: Sustained Clinical Benefit in Severe Hemoglobinopathies
J. Ribeil, S. Hacein-Bey-Abina, E. Payen, M. Semeraro +25 more
20166 citations
Semantic Scholar
Advances in stem cell transplantation and gene therapy in the (cid:1) -hemoglobinopathies
E. Payen, P. Leboulch
20126 citations
Semantic Scholar
Death switch for gene therapy: application to erythropoietin transgene expression.
D. S. Souza, D. Spencer, T. Salles, M. A. Salomão +5 more
2010Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas6 citations Open access
Semantic Scholar
Evolutionary conservation of a microsatellite in the Wilms tumour (WT) gene: mapping in sheep and cattle.
Daniel Vaiman, E. Pailhoux, E. Payen, N. Saïdi-Mehtar +1 more
1995Cytogenetics and Cell Genetics6 citations
Semantic Scholar
Efficacy and Safety of Gene Therapy for β-Thalassemia.
E. Payen
2022New England Journal of Medicine5 citations
Semantic Scholar
Enhanced Cell-Based Detection of Parvovirus B19V Infectious Units According to Cell Cycle Status
Céline Ducloux, Bruno You, Amandine Langelé, O. Goupille +3 more
2020Viruses5 citations Open access
Semantic Scholar
Enhanced Transduction of Macaca fascicularis Hematopoietic Cells with Chimeric Lentiviral Vectors
K. Sii-Felice, Javier Castillo Padilla, Francis Relouzat, Joëlle Cheuzeville +5 more
2019Human Gene Therapy3 citations
Semantic Scholar
Activation and inhibition of the erythropoietin receptor by a membrane-anchored erythropoietin.
O. Nègre, F. Fusil, A. Henri, J. Villette +3 more
2008Experimental Hematology3 citations Open access
Semantic Scholar

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