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Lena Schultz · SciRah

Researcher profile · Semantic Scholar

Lena Schultz

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Lena Schultz — researcher profile on SciRah

h-index: 11
Works: 21
Citations: 740

Most-cited papers

A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells
G. Nguyen, T. Dexheimer, Andrew S. Rosenthal, Wai-Kit Chu +15 more
2013Chemistry and Biology149 citations Open access
Semantic Scholar
Potent and Selective Inhibitors of Human Reticulocyte 12/15-Lipoxygenase as Anti-Stroke Therapies
Ganesha Rai, Netra Joshi, Joo Eun Jung, Yu Liu +12 more
2014Journal of Medicinal Chemistry96 citations Open access
Semantic Scholar
A Miniaturized Screen for Inhibitors of Jumonji Histone Demethylases
Masaaki Sakurai, Nathan R. Rose, Lena Schultz, Amy M. Quinn +5 more
2009Molecular Biosystems83 citations Open access
Semantic Scholar
Synthesis and Structure − Activity Relationship Studies of 4 ‐ ( ( 2-Hydroxy-3-methoxybenzyl ) amino ) benzenesulfonamide Derivatives as Potent and Selective Inhibitors of 12-Lipoxygenase
D. Luci, J. Jameson, Adam Yasgar, Giovanni Diaz +15 more
201482 citations
Semantic Scholar
Discovery of Potent and Selective Inhibitors of Human Reticulocyte 15- Lipoxygenase-1
Ganesha Rai, Victor A Kenyon, A. Jadhav, Lena Schultz +7 more
2010Journal of Medicinal Chemistry79 citations Open access
Semantic Scholar
Discovery of Potent and Selective Inhibitors of Human Platelet type 12-Lipoxygenase
Victor A Kenyon, Ganesha Rai, A. Jadhav, Lena Schultz +12 more
2011Journal of Medicinal Chemistry62 citations Open access
Semantic Scholar
Inhibition of Thioredoxin Reductase 1 by Porphyrins and Other Small Molecules Identified By a High Throughput Screening Assay
Stefanie Prast-Nielsen, T. Dexheimer, Lena Schultz, W. Stafford +5 more
2011Free Radical Biology & Medicine42 citations Open access
Semantic Scholar
High-Affinity Inhibitors of Human NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase: Mechanisms of Inhibition and Structure-Activity Relationships
F. Niesen, Lena Schultz, A. Jadhav, C. Bhatia +7 more
2010PLoS ONE39 citations Open access
Semantic Scholar
Discovery of ML355, a Potent and Selective Inhibitor of Human 12-Lipoxygenase
D. Luci, J. Jameson, Adam Yasgar, Giovanni Diaz +14 more
201438 citations
Semantic Scholar
Discovery of ML351, a Potent and Selective Inhibitor of Human 15-Lipoxygenase-1
Ganesha Rai, Netra Joshi, Steve Perry, Adam Yasgar +11 more
201432 citations
Semantic Scholar
A High Throughput Screen Identifies Potent and Selective Inhibitors to Human Epithelial 15-Lipoxygenase-2
J. Jameson, Auric Kantz, Lena Schultz, C. Kalyanaraman +5 more
2014PLoS ONE28 citations Open access
Semantic Scholar
Selective Small Molecule Inhibitors of 12-Human Lipoxygenase (12-hLO)
Ganesha Rai, A. Jadhav, Lena Schultz, Victor A Kenyon +4 more
20117 citations
Semantic Scholar
Potent and selective inhibitors of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD)
A. Jadhav, F. Niesen, Lena Schultz, U. Oppermann +2 more
20114 citations
Semantic Scholar
Steady-state kinetics data for the determination of K i for 15-LOX-2 with MLS000536924.
J. Jameson, Auric Kantz, Lena Schultz, C. Kalyanaraman +5 more
20140 citations Open access
Semantic Scholar
Figure 4, Steady-state kinetics data for the determination of Kic for 12-hLO with inhibitor
Ganesha Rai, A. Jadhav, Lena Schultz, Victor A Kenyon +4 more
20110 citations
Semantic Scholar
Table 4, SAR table for 12-hLO inhibition-Representative Analogs
Ganesha Rai, A. Jadhav, Lena Schultz, Victor A Kenyon +4 more
20110 citations
Semantic Scholar
Table 1, 12-hLO qHTS assay protocol for 1536-well plate format
Ganesha Rai, A. Jadhav, Lena Schultz, Victor A Kenyon +4 more
20110 citations
Semantic Scholar
Table 2, Probe in vitro ADME properties:a
Ganesha Rai, A. Jadhav, Lena Schultz, Victor A Kenyon +4 more
20110 citations
Semantic Scholar
Figure 3, [(a) Proposed mechanism of covalent modification for 8-HQs with aniline nitrogen at C-9].
Ganesha Rai, A. Jadhav, Lena Schultz, Victor A Kenyon +4 more
20110 citations
Semantic Scholar
Table 5, SAR table for 12-hLO inhibition-Enantiomers
Ganesha Rai, A. Jadhav, Lena Schultz, Victor A Kenyon +4 more
20110 citations
Semantic Scholar
Figure 2, 3D scatter plot of inhibitors from 12-hLO qHTS
Ganesha Rai, A. Jadhav, Lena Schultz, Victor A Kenyon +4 more
20110 citations
Semantic Scholar

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A. Jadhav×21
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A. Jadhav — researcher profile on SciRah
A. Simeonov×21
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Victor A Kenyon×12

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Netra Joshi — researcher profile on SciRah

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