Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

G. Sutendra · SciRah

Researcher profile · Semantic Scholar

G. Sutendra

Share profile

G. Sutendra — researcher profile on SciRah

h-index: 30
Works: 133
Citations: 5,352

Most-cited papers

A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation.
G. Sutendra, A. Kinnaird, P. Dromparis, R. Paulin +6 more
2014Cell606 citations Open access
Semantic Scholar
Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology
G. Sutendra, E. Michelakis
2013Frontiers in Oncology261 citations Open access
Semantic Scholar
The metabolic basis of pulmonary arterial hypertension.
G. Sutendra, E. Michelakis
2014Cell Metabolism240 citations Open access
Semantic Scholar
A metabolic remodeling in right ventricular hypertrophy is associated with decreased angiogenesis and a transition from a compensated to a decompensated state in pulmonary hypertension
G. Sutendra, P. Dromparis, R. Paulin, Sotirios D. Zervopoulos +3 more
2013Journal of molecular medicine219 citations
Semantic Scholar
Sirtuin 3 deficiency is associated with inhibited mitochondrial function and pulmonary arterial hypertension in rodents and humans.
R. Paulin, P. Dromparis, G. Sutendra, V. Gurtu +7 more
2014Cell Metabolism192 citations Open access
Semantic Scholar
Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer
G. Sutendra, P. Dromparis, A. Kinnaird, T. Stenson +4 more
2013Oncogene187 citations
Semantic Scholar
Attenuating Endoplasmic Reticulum Stress as a Novel Therapeutic Strategy in Pulmonary Hypertension
P. Dromparis, R. Paulin, T. Stenson, A. Haromy +2 more
2013Circulation171 citations
Semantic Scholar
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis
L. Tian, Danchen Wu, A. Dasgupta, Kuang-Hueih Chen +11 more
2020Circulation Research131 citations Open access
Semantic Scholar
Uncoupling Protein 2 Deficiency Mimics the Effects of Hypoxia and Endoplasmic Reticulum Stress on Mitochondria and Triggers Pseudohypoxic Pulmonary Vascular Remodeling and Pulmonary Hypertension
P. Dromparis, R. Paulin, G. Sutendra, Andrew C. Qi +2 more
2013Circulation Research122 citations Open access
Semantic Scholar
A miR-208–Mef2 Axis Drives the Decompensation of Right Ventricular Function in Pulmonary Hypertension
R. Paulin, G. Sutendra, V. Gurtu, P. Dromparis +4 more
2015Circulation Research109 citations Open access
Semantic Scholar
Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension
O. Boucherat, Thibaut Peterlini, A. Bourgeois, V. Nadeau +14 more
2018American Journal of Respiratory and Critical Care Medicine89 citations Open access
Semantic Scholar
Pulmonary Arterial Hypertension: Challenges in Translational Research and a Vision for Change
G. Sutendra, E. Michelakis
2013Science Translational Medicine88 citations
Semantic Scholar
Endothelin Axis Is Upregulated in Human and Rat Right Ventricular Hypertrophy
Jayan Nagendran, G. Sutendra, I. Paterson, H. Champion +6 more
2013Circulation Research81 citations Open access
Semantic Scholar
MFN2-driven mitochondria-to-nucleus tethering allows a non-canonical nuclear entry pathway of the mitochondrial pyruvate dehydrogenase complex.
Sotirios D. Zervopoulos, Aristeidis E. Boukouris, Bruno Saleme, A. Haromy +3 more
2022Molecules and Cells73 citations Open access
Semantic Scholar
Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase.
A. Kinnaird, P. Dromparis, Bruno Saleme, V. Gurtu +10 more
2016European Urology70 citations
Semantic Scholar
Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity
Bruno Saleme, V. Gurtu, Yong-Neng Zhang, A. Kinnaird +4 more
2019Science Translational Medicine67 citations Open access
Semantic Scholar
FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression.
K. Gopal, Bruno Saleme, R. Al Batran, Hanin Aburasayn +9 more
2017American Journal of Physiology. Heart and Circulatory Physiology64 citations Open access
Semantic Scholar
Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.
R. Al Batran, K. Gopal, M. Capozzi, Jadin J. Chahade +20 more
2020Cell Metabolism56 citations Open access
Semantic Scholar
FoxO1 inhibition alleviates type 2 diabetes-related diastolic dysfunction by increasing myocardial pyruvate dehydrogenase activity.
K. Gopal, R. Al Batran, T. Altamimi, A. Greenwell +7 more
2021Cell Reports55 citations Open access
Semantic Scholar
Fluorine-18 Prostate-Specific Membrane Antigen–1007 PET/CT vs Multiparametric MRI for Locoregional Staging of Prostate Cancer
N. Mookerji, Tyler Pfanner, Amaris Hui, Guo-Cheng Huang +21 more
2024JAMA Oncology49 citations Open access
Semantic Scholar
iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death
M. Notari, Ying Hu, G. Sutendra, Z. Dedeic +16 more
2015Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure
Maria Areli Lorenzana-Carrillo, K. Gopal, Nikole J. Byrne, Saymon Tejay +11 more
2022Science Translational Medicine34 citations
Semantic Scholar
Caspase cleavage of iASPP potentiates its ability to inhibit p53 and NF-κB
Ying Hu, Wenjie Ge, Xingwen Wang, G. Sutendra +5 more
2015OncoTarget23 citations Open access
Semantic Scholar
The impact of current and novel anti-diabetic therapies on cardiovascular risk.
J. Ussher, G. Sutendra, Jagdip S. Jaswal
2012Future Cardiology21 citations
Semantic Scholar
Cell autonomous role of iASPP deficiency in causing cardiocutaneous disorders
Z. Dedeic, G. Sutendra, Ying Hu, K. Chung +8 more
2018Cell Death and Differentiation20 citations Open access
Semantic Scholar
Breast cancer diagnosis is associated with relative left ventricular hypertrophy and elevated endothelin-1 signaling
Zaid H. Maayah, Shingo Takahara, Abrar S. Alam, M. Ferdaoussi +6 more
2020BMC Cancer17 citations Open access
Semantic Scholar
Pioglitazone inhibits HIF-1α-dependent angiogenesis in rats by paracrine and direct effects on endothelial cells
P. Dromparis, G. Sutendra, R. Paulin, S. Proctor +2 more
2014Journal of molecular medicine17 citations Open access
Semantic Scholar
Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy.
Jordan S. F. Chan, Seyed Amirhossein Tabatabaei Dakhili, Maria Areli Lorenzana-Carrillo, K. Gopal +16 more
2024Cell Reports14 citations Open access
Semantic Scholar
A Novel Drp1 GTPase inhibitor, Drpitor1a: Efficacy in Pulmonary Hypertension
Danchen Wu, R. D. Jansen-van Vuuren, A. Dasgupta, R. Al-Qazazi +18 more
2024HYPERTENSION14 citations Open access
Semantic Scholar
The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity.
R. Al Batran, K. Gopal, Hanin Aburasayn, Amina Eshreif +9 more
2019JCI Insight14 citations Open access
Semantic Scholar
Ser-796 of β-galactosidase (Escherichia coli) plays a key role in maintaining a balance between the opened and closed conformations of the catalytically important active site loop.
L. J. Jancewicz, R. Wheatley, G. Sutendra, Michael Lee +2 more
2012Archives of Biochemistry and Biophysics12 citations
Semantic Scholar
Endothelin Receptor Blocker Reverses Breast Cancer–Induced Cardiac Remodeling
Zaid H. Maayah, M. Ferdaoussi, Aristeidis E. Boukouris, Shingo Takahara +7 more
2023JACC CardioOncology11 citations Open access
Semantic Scholar
Regulation of immunological tolerance by the p53-inhibitor iASPP
Elliot H. Akama-Garren, P. Miller, Thomas M. Carroll, Michael Tellier +8 more
2023Cell Death and Disease11 citations Open access
Semantic Scholar
A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer.
Aristeidis E. Boukouris, Yong-Neng Zhang, Bruno Saleme, A. Kinnaird +12 more
2022Cell Reports11 citations Open access
Semantic Scholar
TRIM35 Monoubiquitinates H2B in Cardiac Cells, Implications for Heart Failure
Maria Areli Lorenzana-Carrillo, Saymon Tejay, Joseph Nanoa, Guo-Cheng Huang +8 more
2024Circulation Research10 citations
Semantic Scholar
SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes
Yong-Neng Zhang, Sotirios D. Zervopoulos, Aristeidis E. Boukouris, Maria Areli Lorenzana-Carrillo +8 more
2021Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease10 citations Open access
Semantic Scholar
p53‐Mediated Repression of the PGC1A (PPARG Coactivator 1α) and APLNR (Apelin Receptor) Signaling Pathways Limits Fatty Acid Oxidation Energetics: Implications for Cardio‐oncology
Bruno Saleme, Subhash K. Das, Yong-Neng Zhang, Aristeidis E. Boukouris +6 more
2020Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease10 citations Open access
Semantic Scholar
Cysteine oxidation of a redox hub within complex I can facilitate electron transport chain supercomplex formation
Run-Tai Chen, Seyed Amirhossein Tabatabaei Dakhili, Rokas Gerulskis, Yuan-Yuan Zhao +10 more
2025Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Ser-796 of Beta-Galactosidase (E. coli) Plays a Key Role in Maintaining an Optimum Balance between the Opened and Closed Conformations of the Catalytically Important Active Site Loop
L. J. Jancewicz, R. Wheatley, G. Sutendra, M. Lee +2 more
20127 citations
Semantic Scholar
Interaction with p53 explains a pro-proliferative function for VHL in cancer
A. Kinnaird, Aristeidis E. Boukouris, Bruno Saleme, P. Dromparis +4 more
2020Journal of molecular medicine6 citations
Semantic Scholar
The iron paradigm of pulmonary arterial hypertension: Popeye knows best.
G. Sutendra, S. Bonnet
2015Circulation Research6 citations
Semantic Scholar
Tumour initiated purinergic signalling promotes cardiomyocyte RBFOX1 degradation and cardiotoxicity from DNA damaging anticancer agents
Saymon Tejay, Maria Areli Lorenzana-Carrillo, Guo-Cheng Huang, Seyed Amirhossein Tabatabaei Dakhili +10 more
2025Nature Communications5 citations Open access
Semantic Scholar
A Similar Metabolic Profile Between the Failing Myocardium and Tumor Could Provide Alternative Therapeutic Targets in Chemotherapy-Induced Cardiotoxicity
Bruno Saleme, G. Sutendra
2018Frontiers in Cardiovascular Medicine4 citations Open access
Semantic Scholar
Uncoupling Protein 2 Deficiency Mimics the Effects of Hypoxia and Endoplasmic Reticulum Stress on Mitochondria and Triggers Pseudo-Hypoxic Pulmonary Vascular Remodeling and Pulmonary Hypertension
P. Dromparis, R. Paulin, G. Sutendra, Andrew C. Qi +2 more
20133 citations
Semantic Scholar
Selective translation of ZNF281 as part of the integrated stress response system has therapeutic relevance for cardio-oncology.
Maria Areli Lorenzana-Carrillo, Saymon Tejay, Guo-Cheng Huang, Joseph Nanoa +10 more
2026Science Translational Medicine2 citations
Semantic Scholar
Hyperacute response proteins synthesized on γ-tubulin-FTO-MARK4 translation microdomains regulate cancer's acute stress response.
Bruno Saleme, Saymon Tejay, K. Dembélé, Rabih Abou Farraj +14 more
2025Cell Reports2 citations Open access
Semantic Scholar
Critical Contribution of Cardiac Myofibroblasts in Right Ventricular Failure and the Role of UCP2 SNPs in the Predisposition to RV Decompensation in Pulmonary Arterial Hypertension
Yong-Neng Zhang, S. Bonnet, S. Provencher, Ji-Yuan Piao +9 more
2025bioRxiv2 citations Open access
Semantic Scholar
Metabolic light absorption, scattering, and emission (MetaLASE) microscopy
Brendon S. Restall, Nathaniel J. M. Haven, Matthew T Martell, Brendyn D. Cikaluk +7 more
2024Science Advances2 citations Open access
Semantic Scholar
Three-dimensional spatial localization and volume estimation of prostate tumors using 18F-PSMA-1007 PET/CT versus multiparametric MRI
Guo-Cheng Huang, Patrick Albers, Nikhile Mookerji, Tyler Pfanner +22 more
2024European Journal of Nuclear Medicine and Molecular Imaging2 citations Open access
Semantic Scholar
Pioglitazone inhibits HIF-1α-dependent angiogenesis in rats by paracrine and direct effects on endothelial cells
P. Dromparis, G. Sutendra, R. Paulin, S. Proctor +2 more
2014Journal of molecular medicine2 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

E. Michelakis×30
Invite
E. Michelakis — researcher profile on SciRah
A. Haromy×14
Invite
A. Haromy — researcher profile on SciRah
A. Kinnaird×13
Invite
A. Kinnaird — researcher profile on SciRah
P. Dromparis×13
Invite
P. Dromparis — researcher profile on SciRah

×13

Invite

Bruno Saleme — researcher profile on SciRah

Invite

R. Paulin — researcher profile on SciRah

Invite

J. Ussher — researcher profile on SciRah

Sotirios D. Zervopoulos×8

Invite

Sotirios D. Zervopoulos — researcher profile on SciRah

Invite

S. Bonnet — researcher profile on SciRah

Aristeidis E. Boukouris×8

Invite

Aristeidis E. Boukouris — researcher profile on SciRah

Yong-Neng Zhang×8

Invite

Yong-Neng Zhang — researcher profile on SciRah

Yuan-Yuan Zhao×8

Invite

Yuan-Yuan Zhao — researcher profile on SciRah