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T. McCloskey · SciRah

Researcher profile · Semantic Scholar

T. McCloskey

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T. McCloskey — researcher profile on SciRah

h-index: 22
Works: 43
Citations: 2,092

Most-cited papers

Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals.
N. Oyaizu, T. McCloskey, Maria Coronesi, N. Chirmule +2 more
1993Blood273 citations
Semantic Scholar
Immune Hyperactivation of HIV-1-Infected T Cells Mediated by Tat and the CD28 Pathway
M. Ott, S. Emiliani, C. V. Van Lint, G. Herbein +5 more
1997Science228 citations
Semantic Scholar
Cross-linking of CD4 molecules upregulates Fas antigen expression in lymphocytes by inducing interferon-gamma and tumor necrosis factor-alpha secretion.
N. Oyaizu, T. McCloskey, S. Than, R. Hu +2 more
1994Blood221 citations Open access
Semantic Scholar
Monocytes express Fas ligand upon CD4 cross-linking and induce CD4+ T cells apoptosis: a possible mechanism of bystander cell death in HIV infection.
N. Oyaizu, Y. Adachi, F. Hashimoto, T. McCloskey +4 more
1997Journal of Immunology179 citations Open access
Semantic Scholar
Dual role of HIV Tat in regulation of apoptosis in T cells.
T. McCloskey, M. Ott, E. Tribble, S. Khan +5 more
1997Journal of Immunology157 citations
Semantic Scholar
IL-2 rescues in vitro lymphocyte apoptosis in patients with HIV infection: correlation with its ability to block culture-induced down-modulation of Bcl-2.
Y. Adachi, N. Oyaizu, S. Than, T. McCloskey +1 more
1996Journal of Immunology121 citations Open access
Semantic Scholar
Aggregates of oxidized proteins (lipofuscin) induce apoptosis through proteasome inhibition and dysregulation of proapoptotic proteins.
S. R. Powell, Ping Wang, A. Divald, S. Teichberg +4 more
2005Free Radical Biology & Medicine116 citations
Semantic Scholar
HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71).
N. Chirmule, T. McCloskey, R. Hu, V. Kalyanaraman +1 more
1995Journal of Immunology85 citations Open access
Semantic Scholar
Expression of the Fas antigen in patients infected with human immunodeficiency virus.
T. McCloskey, N. Oyaizu, Mark H. Kaplan, S. Pahwa
1995Cytometry78 citations Open access
Semantic Scholar
CD4 T lymphocytes are primed to express Fas ligand by CD4 cross-linking and to contribute to CD8 T-cell apoptosis via Fas/FasL death signaling pathway.
Masaki Tateyama, Naoki Oyaizu, T. McCloskey, Soe Than +1 more
2000Blood75 citations
Semantic Scholar
Immunophenotyping of T lymphocytes by three-color flow cytometry in healthy newborns, children, and adults.
T. McCloskey, T. Cavaliere, S. Bakshi, Rita G. Harper +3 more
1997Clinical Immunology and Immunopathology57 citations Open access
Semantic Scholar
Use of a flow cytometric assay to quantitate apoptosis in human lymphocytes.
T. McCloskey, Naoki Oyaizu, Maria Coronesi, S. Pahwa
1994Clinical Immunology and Immunopathology55 citations Open access
Semantic Scholar
Requirement of p56lck in T-cell receptor/CD3-mediated apoptosis and Fas-ligand induction in Jurkat cells.
Naoki Oyaizu, Soe Than, T. McCloskey, S. Pahwa
1995Biochemical and Biophysical Research Communications - BBRC50 citations
Semantic Scholar
Role of receptor occupancy assays by flow cytometry in drug development
Jennifer J. Stewart, Cherie Green, N. Jones, M. Liang +12 more
2016Cytometry. Part B, Clinical cytometry37 citations Open access
Semantic Scholar
Comparison of Seven Quantitative Assays to Assess Lymphocyte Cell Death during HIV Infection: Measurement of Induced Apoptosis in Anti-Fas-Treated Jurkat Cells and Spontaneous Apoptosis in Peripheral Blood Mononuclear Cells from Children Infected with HIV
T. McCloskey, Surendra J. Chavan, S. M. LakshmiTamma, S. Pahwa
1998AIDS Research and Human Retroviruses36 citations
Semantic Scholar
Immunophenotypic analysis of peripheral blood mononuclear cells undergoing in vitro apoptosis after isolation from human immunodeficiency virus-infected children.
T. McCloskey, S. Bakshi, Soe Than, Parisa Arman +1 more
1998Blood34 citations
Semantic Scholar
Alterations in apoptosis of cord and adult peripheral blood mononuclear cells induced by in vitro infection with respiratory syncytial virus.
L. R. Krilov, T. McCloskey, S. H. Harkness, L. Pontrelli +1 more
2000Journal of Infectious Diseases33 citations Open access
Semantic Scholar
Signals transduced through the CD4 molecule interfere with TCR/CD3-mediated ras activation leading to T cell anergy/apoptosis.
S. M. LakshmiTamma, N. Chirmule, T. McCloskey, Naoki Oyaizu +2 more
1997Clinical Immunology and Immunopathology28 citations Open access
Semantic Scholar
Discordant expression of perforin and granzyme A in total and HIV-specific CD8 T lymphocytes of HIV infected children and adolescents
V. Haridas, T. McCloskey, R. Pahwa, S. Pahwa
2003AIDS (London)27 citations Open access
Semantic Scholar
CD8+ T cells in HIV disease exhibit cytokine receptor perturbation and poor T cell receptor activation but are responsive to gamma-chain cytokine-driven proliferation.
R. Pahwa, T. McCloskey, Olga C. Aroniadis, N. Strbo +2 more
2006Journal of Infectious Diseases26 citations
Semantic Scholar
Immunophenotypic analysis of HIV-infected children: alterations within the first year of life, changes with disease progression, and longitudinal analyses of lymphocyte subsets.
T. McCloskey, Nina Kohn, Martin Lesser, S. Bakshi +1 more
2001Cytometry23 citations
Semantic Scholar
Mechanism of apoptosis in peripheral blood mononuclear cells of HIV-infected patients.
Naoki Oyaizu, T. McCloskey, Soe Than, R. Hu +1 more
1995Advances in Experimental Medicine and Biology23 citations
Semantic Scholar
Alterations in T-Cell Receptor Vβ Repertoire of CD4 and CD8 T Lymphocytes in Human Immunodeficiency Virus-Infected Children
Monica Kharbanda, T. McCloskey, R. Pahwa, Mei Sun +1 more
2003Clinical Diagnostic Laboratory Immunology22 citations Open access
Semantic Scholar
CD95 expression and apoptosis during pediatric HIV infection: early upregulation of CD95 expression.
T. McCloskey, Naoki Oyaizu, S. Bakshi, R. Kowalski +2 more
1998Clinical Immunology and Immunopathology21 citations Open access
Semantic Scholar
Apoptosis in T-Lymphocyte Subsets in Human Immunodeficiency Virus-Infected Children Measured Immediately Ex Vivo and following In Vitro Activation
T. Niehues, T. McCloskey, J. Ndagijimana, G. Horneff +2 more
2001Clinical Diagnostic Laboratory Immunology15 citations Open access
Semantic Scholar
HIV-1 gp120 Blocks Jacalin-Induced Proliferative Response in CD4+T Cells: Jacalin as a Useful Surrogate Marker for Qualitative and Quantitative Deficiency of CD4+T Cells in HIV-1 Infection1
S. Tamma, N. Oyaizu, T. McCloskey, V. Kalyanaraman +1 more
199615 citations Open access
Semantic Scholar
Inhibition of CD4 cross-linking-induced lymphocytes apoptosis by vesnarinone as a novel immunomodulating agent: vesnarinone inhibits Fas expression and apoptosis by blocking cytokine secretion.
Naoki Oyaizu, T. McCloskey, Soe Than, S. Pahwa
1996Blood14 citations
Semantic Scholar
Human immunodeficiency virus gag and pol-specific CD8 T cells in perinatal HIV infection.
T. McCloskey, V. Haridas, R. Pahwa, S. Pahwa
2001Cytometry10 citations
Semantic Scholar
T cell receptor V beta repertoire of the antigen specific CD8 T lymphocyte subset of HIV infected children.
T. McCloskey, V. Haridas, R. Pahwa, S. Pahwa
2002AIDS (London)9 citations
Semantic Scholar
Response to Superantigen Stimulation in Peripheral Blood Mononuclear Cells from Children Perinatally Infected with Human Immunodeficiency Virus and Receiving Highly Active Antiretroviral Therapy
T. McCloskey, V. Haridas, L. Pontrelli, S. Pahwa
2004Clinical Diagnostic Laboratory Immunology8 citations Open access
Semantic Scholar
T cell receptor Vβ repertoire of the antigen specific CD8 T lymphocyte subset of HIV infected children
T. McCloskey, V. Haridas, R. Pahwa, S. Pahwa
20028 citations Open access
Semantic Scholar
Responses of Monocytes in Peripheral Blood Mononuclear Leukocytes (PBMLs) Exposed to Respiratory Syncytial Virus (RSV) In Vitro † 868
L. Krilov, T. McCloskey, S. H. Harkness, S. Pahwa
1998Pediatric Research4 citations
Semantic Scholar
HIV-1 gp 120 blocks jacalin-induced proliferative response in CD4+ T cells: jacalin as a useful surrogate marker for qualitative and quantitative deficiency of CD4+ T cells in HIV-1 infection.
S. Tamma, N. Oyaizu, T. McCloskey, V. Kalyanaraman +1 more
1996Clinical Immunology and Immunopathology3 citations
Semantic Scholar
Flow Cytometry and Clinical Trials
C. G. Hill, T. McCloskey
20111 citations
Semantic Scholar
Flow Cytometric Detection and Quantification of Apoptotic Cells
T. McCloskey, Barbara N. Phenix, S. Pahwa
20061 citations
Semantic Scholar
Immunomodulation in an Infant with Familial Hemophagocytic Lymphohistiocytosis Following Chemotherapy
M. Frieri, G. Beck, P. Cardenas, Fang-Wang Soo +3 more
19991 citations
Semantic Scholar
Abstract 5115: Enhancing data quality for clinical studies of investigational cancer immunotherapy drug candidates by a new data analytics tool
Cheng-Sen Xue, J. Cuomo, Melissa L. Baptiste, Kai Chen +2 more
2019Bioinformatics, Convergence Science, and Systems Biology0 citations
Semantic Scholar
Flow cytometry for evaluation and investigation of human immunodeficiency virus infection.
T. McCloskey
2001Methods in Cell Biology0 citations
Semantic Scholar
Immunomodulation In An Infant With Familial Hemophagocytic Lymphohistiocytosis (FHLH) Following Chemotherapy
M. Frieri, G. Beck, P. Cardenas, Soo-Fang Wang +4 more
1999Pediatric Research0 citations
Semantic Scholar
TUNEL Assay Quantification of Apoptosis in Peripheral Blood Mononuclear Leukocytes Exposed to Respiratory Syncytial Virus (RSV)
L. Krilov, T. McCloskey, L. Pontrelli, S. H. Harkness +1 more
19990 citations
Semantic Scholar
Flow cytometry based procedures for the measurement of apoptosis applicable to the investigation of HIV infection
T. McCloskey, S. Pahwa
19990 citations
Semantic Scholar
Early Upregulation of CD95 Expression in HIV Infected Infants under One Year of Age. ♦ 52
T. McCloskey, S. Bakshi, S. Than, N. Kohn +1 more
1997Pediatric Research0 citations
Semantic Scholar
Role of monocytes on cd4 crosslinking-induced t cells apoptosis in hiv infection
N. Qvaizu, Y. Adachi, T. McCloskey, S. Than +5 more
19960 citations
Semantic Scholar

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S. Pahwa×35
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V. Haridas×6
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Naoki Oyaizu×6
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N. Oyaizu×5
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Soe Than — researcher profile on SciRah

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V. Kalyanaraman×4

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N. Chirmule — researcher profile on SciRah

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R. Hu — researcher profile on SciRah

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