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T. Abbruscato · SciRah

Researcher profile · Semantic Scholar

T. Abbruscato

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T. Abbruscato — researcher profile on SciRah

h-index: 41
Works: 128
Citations: 4,804

Most-cited papers

The Role of Glucose Transporters in Brain Disease: Diabetes and Alzheimer’s Disease
Kaushik K Shah, S. deSilva, T. Abbruscato
2012International Journal of Molecular Sciences276 citations Open access
Semantic Scholar
Blood-Brain Barrier Protection as a Therapeutic Strategy for Acute Ischemic Stroke
A. Sifat, Bhuvaneshwar Vaidya, T. Abbruscato
2017AAPS Journal156 citations Open access
Semantic Scholar
Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity
S. Prasad, Ravi K. Sajja, M. Kaisar, Jee-Hyun Park +4 more
2017Redox Biology126 citations Open access
Semantic Scholar
A functional role for sodium dependent glucose transport across the blood-brain barrier during oxygen glucose deprivation
Sharanya Vemula, Karen E. Roder, Tian-Zhi Yang, G. Bhat +2 more
2008Journal of Pharmacology and Experimental Therapeutics119 citations Open access
Semantic Scholar
Offsetting the impact of smoking and e-cigarette vaping on the cerebrovascular system and stroke injury: Is Metformin a viable countermeasure?
M. Kaisar, Heidi Villalba, S. Prasad, Taylor Liles +4 more
2017Redox Biology111 citations Open access
Semantic Scholar
Evaluation of human nasal RPMI 2650 cells grown at an air-liquid interface as a model for nasal drug transport studies.
Shu-Hua Bai, Tian-Zhi Yang, T. Abbruscato, F. Ahsan
2008Journal of Pharmacy and Science102 citations
Semantic Scholar
Nicotine Exacerbates Brain Edema during In Vitro and In Vivo Focal Ischemic Conditions
Jennifer R. Paulson, Tian-Zhi Yang, P. Selvaraj, A. Mdzinarishvili +4 more
2010Journal of Pharmacology and Experimental Therapeutics76 citations Open access
Semantic Scholar
Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with co-factors p300/CBP
Shao-Man Yin, Š. Kaluz, N. Devi, A. Jabbar +13 more
2012Clinical Cancer Research67 citations Open access
Semantic Scholar
Brain Energy Metabolism in Ischemic Stroke: Effects of Smoking and Diabetes
A. Sifat, Saeideh Nozohouri, Sabrina Rahman Archie, E. A. Chowdhury +1 more
2022International Journal of Molecular Sciences66 citations Open access
Semantic Scholar
Aspirin inhibits camptothecin-induced p21CIP1 levels and potentiates apoptosis in human breast cancer cells.
L. Alfonso, K. Srivenugopal, T. Arumugam, T. Abbruscato +2 more
2009International Journal of Oncology64 citations Open access
Semantic Scholar
NMDA receptor-antagonistic properties of hyperforin, a constituent of St. John's Wort.
Vikas Kumar, A. Mdzinarishvili, C. Kiewert, T. Abbruscato +3 more
2006Journal of Pharmacological Sciences63 citations Open access
Semantic Scholar
Nicotine and electronic cigarette (E-Cig) exposure decreases brain glucose utilization in ischemic stroke
A. Sifat, Bhuvaneshwar Vaidya, M. Kaisar, L. Cucullo +1 more
2018Journal of Neurochemistry61 citations Open access
Semantic Scholar
Opioid receptor agonists reduce brain edema in stroke.
Li Yang, Hezhen Wang, Kaushik K Shah, V. Karamyan +1 more
2011Brain Research61 citations
Semantic Scholar
Evaluation of bEnd5 cell line as an in vitro model for the blood-brain barrier under normal and hypoxic/aglycemic conditions.
Tian-Zhi Yang, Karen E. Roder, T. Abbruscato
2007Journal of Pharmacy and Science59 citations
Semantic Scholar
Neuroprotection in mice by NGP1-01 after transient focal brain ischemia.
Jiu-Kuan Hao, A. Mdzinarishvili, T. Abbruscato, J. Klein +3 more
2008Brain Research56 citations
Semantic Scholar
Novel approaches for the delivery of therapeutics in ischemic stroke
Saeideh Nozohouri, A. Sifat, Bhuvaneshwar Vaidya, T. Abbruscato
2020Drug Discovery Today53 citations Open access
Semantic Scholar
Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke
Sejal Sharma, Saeideh Nozohouri, Bhuvaneshwar Vaidya, T. Abbruscato
2021Life Science52 citations Open access
Semantic Scholar
Brain Uptake Kinetics of Nicotine and Cotinine after Chronic Nicotine Exposure
P. Lockman, Ghia McAfee, W. Geldenhuys, C. J. van der Schyf +2 more
2005Journal of Pharmacology and Experimental Therapeutics50 citations
Semantic Scholar
Permeability of Metformin across an In Vitro Blood–Brain Barrier Model during Normoxia and Oxygen-Glucose Deprivation Conditions: Role of Organic Cation Transporters (Octs)
Sejal Sharma, Yong Zhang, K. Akter, Saeideh Nozohouri +4 more
2023Pharmaceutics49 citations Open access
Semantic Scholar
DARK Classics in Chemical Neuroscience: Methamphetamine.
T. Abbruscato, P. Trippier
2018ACS Chemical Neuroscience49 citations
Semantic Scholar
Functional up‐regulation of endopeptidase neurolysin during post‐acute and early recovery phases of experimental stroke in mouse brain
M. Rashid, Naomi J. Wangler, Li Yang, Kaushik K Shah +3 more
2014Journal of Neurochemistry42 citations
Semantic Scholar
Passage Variation of PC12 Cells Results in Inconsistent Susceptibility to Externally Induced Apoptosis
Nihar Kinarivala, Kaushik K Shah, T. Abbruscato, P. Trippier
2016ACS Chemical Neuroscience39 citations Open access
Semantic Scholar
Characterization of Neuroprotective Effects of Biphalin, an Opioid Receptor Agonist, in a Model of Focal Brain Ischemia
Li Yang, Kaushik K Shah, Hezhen Wang, V. Karamyan +1 more
2011Journal of Pharmacology and Experimental Therapeutics39 citations Open access
Semantic Scholar
Tobacco Smoke Chemicals Attenuate Brain-to-Blood Potassium Transport Mediated by the Na,K,2Cl-Cotransporter during Hypoxia-Reoxygenation
Jennifer R. Paulson, Karen E. Roder, Ghia McAfee, D. D. Allen +2 more
2006Journal of Pharmacology and Experimental Therapeutics39 citations
Semantic Scholar
The role of blood-brain barrier transporters in pathophysiology and pharmacotherapy of stroke.
Kaushik K Shah, T. Abbruscato
2014Current pharmaceutical design38 citations
Semantic Scholar
Protein Kinase C Family Members as a Target for Regulation of Blood–Brain Barrier Na,K,2Cl-Cotransporter During In Vitro Stroke Conditions and Nicotine Exposure
Tian-Zhi Yang, Karen E. Roder, G. Bhat, T. Thekkumkara +1 more
2006Pharmaceutical Research35 citations
Semantic Scholar
Metformin ameliorates neuroinflammatory environment for neurons and astrocytes during in vitro and in vivo stroke and tobacco smoke chemical exposure: Role of Nrf2 activation
K. Akter, Sejal Sharma, A. Sifat, Yong Zhang +3 more
2024Redox Biology34 citations Open access
Semantic Scholar
The Role of Smoking and Nicotine in the Transmission and Pathogenesis of COVID-19
A. Sifat, Saeideh Nozohouri, Heidi Villalba, Bhuvaneshwar Vaidya +1 more
2020Journal of Pharmacology and Experimental Therapeutics34 citations Open access
Semantic Scholar
Nicotine pre-exposure reduces stroke-induced glucose transporter-1 activity at the blood–brain barrier in mice
Kaushik K Shah, P. Boreddy, T. Abbruscato
2015Fluids and Barriers of the CNS33 citations Open access
Semantic Scholar
Maternal e-cigarette use can disrupt postnatal blood-brain barrier (BBB) integrity and deteriorates motor, learning and memory function: influence of sex and age
Sabrina Rahman Archie, A. Sifat, Yong Zhang, Heidi Villalba +3 more
2023Fluids and Barriers of the CNS32 citations Open access
Semantic Scholar
In vitro and in vivo efficacy of a potent opioid receptor agonist, biphalin, compared to subtype-selective opioid receptor agonists for stroke treatment
Li Yang, M. R. Islam, V. Karamyan, T. Abbruscato
2015Brain Research32 citations Open access
Semantic Scholar
Peptidase neurolysin functions to preserve the brain after ischemic stroke in male mice
Srinidhi Jayaraman, Abdullah Al Shoyaib, J. Kocot, Heidi Villalba +8 more
2019Journal of Neurochemistry31 citations Open access
Semantic Scholar
Prenatal electronic cigarette exposure decreases brain glucose utilization and worsens outcome in offspring hypoxic–ischemic brain injury
A. Sifat, Saeideh Nozohouri, Heidi Villalba, Abdullah Al Shoyaib +3 more
2019Journal of Neurochemistry30 citations
Semantic Scholar
Comparative assessment of in vitro BBB tight junction integrity following exposure to cigarette smoke and e-cigarette vapor: a quantitative evaluation of the protective effects of metformin using small-molecular-weight paracellular markers
Hossam Kadry, Behnam Noorani, U. Bickel, T. Abbruscato +1 more
2021Fluids and Barriers of the CNS29 citations Open access
Semantic Scholar
Brain Delivery of a Potent Opioid Receptor Agonist, Biphalin during Ischemic Stroke: Role of Organic Anion Transporting Polypeptide (OATP)
Thamer H. Albekairi, Bhuvaneshwar Vaidya, Ronak Patel, Saeideh Nozohouri +5 more
2019Pharmaceutics27 citations Open access
Semantic Scholar
The neuroprotective role of the brain opioid system in stroke injury.
Bhuvaneshwar Vaidya, A. Sifat, V. Karamyan, T. Abbruscato
2018Drug Discovery Today27 citations
Semantic Scholar
Potential role of astrocyte angiotensin converting enzyme 2 in the neural transmission of COVID-19 and a neuroinflammatory state induced by smoking and vaping
Yong Zhang, Sabrina Rahman Archie, Yashwardhan Ghanwatkar, Sejal Sharma +5 more
2022Fluids and Barriers of the CNS25 citations Open access
Semantic Scholar
Neurovascular unit transport responses to ischemia and common coexisting conditions: smoking and diabetes.
A. Sifat, Bhuvaneshwar Vaidya, Heidi Villalba, Thamer H. Albekairi +1 more
2019American Journal of Physiology - Cell Physiology25 citations Open access
Semantic Scholar
Enkephalin-Fentanyl Multifunctional Opioids as Potential Neuroprotectants for Ischemic Stroke Treatment.
M. R. Islam, Li Yang, Ye-On S. Lee, V. Hruby +2 more
2016Current pharmaceutical design25 citations
Semantic Scholar
Preparation and preliminary characterization of recombinant neurolysin for in vivo studies.
Naomi J. Wangler, Srinidhi Jayaraman, Rui Zhu, Y. Mechref +3 more
2016Journal of Biotechnology23 citations
Semantic Scholar
Biological determinants impact the neurovascular toxicity of nicotine and tobacco smoke: a pharmacokinetic and pharmacodynamic perspective
Sabrina Rahman Archie, Sejal Sharma, Elizabeth Burks, T. Abbruscato
2022Neurotoxicology22 citations Open access
Semantic Scholar
Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability
Md. Shafikur Rahman, Shikha Kumari, S. H. Esfahani, Saeideh Nozohouri +8 more
2021Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
An in vitro model of ischemic stroke.
Li Yang, Kaushik K Shah, T. Abbruscato
2012Methods in molecular biology19 citations
Semantic Scholar
Short-term exposure to JUUL electronic cigarettes can worsen ischemic stroke outcome
A. Sifat, Sabrina Rahman Archie, Saeideh Nozohouri, Heidi Villalba +7 more
2022Fluids and Barriers of the CNS18 citations Open access
Semantic Scholar
Potential role of myo-inositol to improve ischemic stroke outcome in diabetic mouse.
Heidi Villalba, Kaushik K Shah, Thamer H. Albekairi, A. Sifat +2 more
2018Brain Research18 citations
Semantic Scholar
Evaluation of Systemic and Brain Pharmacokinetic Parameters for Repurposing Metformin Using Intravenous Bolus Administration.
Sejal Sharma, Yong Zhang, Dhavalkumar Patel, K. Akter +7 more
2024Journal of Pharmacology and Experimental Therapeutics14 citations Open access
Semantic Scholar
Identification and Characterization of Two Structurally Related Dipeptides that Enhance Catalytic Efficiency of Neurolysin
Srinidhi Jayaraman, J. Kocot, S. H. Esfahani, Naomi J. Wangler +8 more
2021Journal of Pharmacology and Experimental Therapeutics14 citations
Semantic Scholar
Drug abuse and the neurovascular unit.
R. Egleton, T. Abbruscato
2014Advances in Pharmacology14 citations
Semantic Scholar
Impact of in-utero electronic cigarette exposure on neonatal neuroinflammation, oxidative stress and mitochondrial function
Sabrina Rahman Archie, A. Sifat, David Mara, Yeseul Ahn +4 more
2023Frontiers in Pharmacology12 citations Open access
Semantic Scholar
Dental Pulp-Derived Stem Cells Preserve Astrocyte Health During Induced Gliosis by Modulating Mitochondrial Activity and Functions
Derek Barthels, Prateeksha Prateeksha, Saeideh Nozohouri, Heidi Villalba +7 more
2022Cellular and molecular neurobiology12 citations
Semantic Scholar

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