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R. Egleton · SciRah

Researcher profile · Semantic Scholar

R. Egleton

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R. Egleton — researcher profile on SciRah

h-index: 34
Works: 89
Citations: 4,814

Most-cited papers

Molecular physiology and pathophysiology of tight junctions in the blood–brain barrier
Jason D. Huber, R. Egleton, T. P. Davis
2001Trends in Neurosciences812 citations
Semantic Scholar
Increased blood–brain barrier permeability and altered tight junctions in experimental diabetes in the rat: contribution of hyperglycaemia and matrix metalloproteinases
B. Hawkins, Tamara F. Lundeen, Kristi M. Norwood, H. Brooks +1 more
2006Diabetologia340 citations Open access
Semantic Scholar
Nicotinic acetylcholine receptors in cancer: multiple roles in proliferation and inhibition of apoptosis.
R. Egleton, K. Brown, P. Dasgupta
2008TIPS - Trends in Pharmacological Sciences274 citations
Semantic Scholar
Inflammatory pain alters blood-brain barrier permeability and tight junctional protein expression.
J. D. Huber, K. Witt, Sharon Hom, R. Egleton +2 more
2001American Journal of Physiology. Heart and Circulatory Physiology271 citations
Semantic Scholar
Nicotine increases in vivo blood-brain barrier permeability and alters cerebral microvascular tight junction protein distribution.
B. Hawkins, T. Abbruscato, R. Egleton, Rachel C. Brown +3 more
2004Brain Research227 citations
Semantic Scholar
Peptide drug modifications to enhance bioavailability and blood-brain barrier permeability.
K. Witt, T. Gillespie, J. D. Huber, R. Egleton +1 more
2001Peptides209 citations
Semantic Scholar
Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations.
T. Brooks, B. Hawkins, J. D. Huber, R. Egleton +1 more
2005American Journal of Physiology. Heart and Circulatory Physiology167 citations Open access
Semantic Scholar
Bioavailability and transport of peptides and peptide drugs into the brain.
R. Egleton, T. Davis
1997Peptides155 citations
Semantic Scholar
Fluorescence imaging of blood-brain barrier disruption.
B. Hawkins, R. Egleton
2006Journal of Neuroscience Methods147 citations
Semantic Scholar
Development of neuropeptide drugs that cross the blood-brain barrier
R. Egleton, T. Davis
2011NeuroRx137 citations Open access
Semantic Scholar
Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability.
E. Bilsky, R. Egleton, Scott A. Mitchell, Michael M. Palian +9 more
2000Journal of Medicinal Chemistry119 citations Open access
Semantic Scholar
Improved bioavailability to the brain of glycosylated Met-enkephalin analogs.
R. Egleton, S. Mitchell, J. D. Huber, J. Janders +5 more
2000Brain Research106 citations
Semantic Scholar
The effect of halogenation on blood-brain barrier permeability of a novel peptide drug.
C. Gentry, R. Egleton, T. Gillespie, T. Abbruscato +3 more
1999Peptides106 citations
Semantic Scholar
Blood-brain barrier tight junctions are altered during a 72-h exposure to lambda-carrageenan-induced inflammatory pain.
Jason D. Huber, Vincent S. Hau, Lindsay K. Borg, Christopher R. Campos +2 more
2002American Journal of Physiology. Heart and Circulatory Physiology102 citations
Semantic Scholar
Protection against hypoxia-induced increase in blood-brain barrier permeability: role of tight junction proteins and NFκB
Rachel C. Brown, K. Mark, R. Egleton, J. D. Huber +2 more
2003Journal of Cell Science100 citations
Semantic Scholar
Peripheral inflammatory hyperalgesia modulates morphine delivery to the brain: a role for P‐glycoprotein
Melissa J. Seelbach, T. Brooks, R. Egleton, T. P. Davis
2007Journal of Neurochemistry98 citations Open access
Semantic Scholar
Angiogenic activity of nicotinic acetylcholine receptors: implications in tobacco-related vascular diseases.
R. Egleton, K. Brown, P. Dasgupta
2009Pharmacology and Therapeutics92 citations
Semantic Scholar
Improved blood-brain barrier penetration and enhanced analgesia of an opioid peptide by glycosylation.
R. Egleton, Scott A. Mitchell, Jason D. Huber, Michael M. Palian +2 more
2001Journal of Pharmacology and Experimental Therapeutics91 citations
Semantic Scholar
Pathophysiology of the blood-brain barrier: animal models and methods.
B. Hawkins, R. Egleton
2008Current Topics in Developmental Biology90 citations
Semantic Scholar
Tight junctions contain oligomeric protein assembly critical for maintaining blood–brain barrier integrity in vivo
G. Mccaffrey, W. Staatz, Carolyn A. Quigley, Nicole Nametz +5 more
2007Journal of Neurochemistry90 citations
Semantic Scholar
Mannitol opening of the blood-brain barrier: regional variation in the permeability of sucrose, but not 86Rb+ or albumin.
Rachel C. Brown, R. Egleton, T. Davis
2004Brain Research89 citations
Semantic Scholar
Modulation of cerebral microvascular permeability by endothelial nicotinic acetylcholine receptors.
B. Hawkins, R. Egleton, T. Davis
2005American Journal of Physiology. Heart and Circulatory Physiology85 citations
Semantic Scholar
Decreased blood-brain barrier permeability to fluorescein in streptozotocin-treated rats.
B. Hawkins, S. Ocheltree, Kristi M. Norwood, R. Egleton
2007Neuroscience Letters76 citations Open access
Semantic Scholar
Comparative changes in the blood-brain barrier and cerebral infarction of SHR and WKY rats.
Sharon Hom, M. A. Fleegal, R. Egleton, Christopher R. Campos +2 more
2007American Journal of Physiology. Regulatory Integrative and Comparative Physiology69 citations Open access
Semantic Scholar
MG624, an α7-nAChR antagonist, inhibits angiogenesis via the Egr-1/FGF2 pathway
K. Brown, Jamie K. Lau, A. Dom, Theodore R. Witte +11 more
2011Angiogenesis63 citations
Semantic Scholar
Antinociceptive Structure-Activity Studies with Enkephalin-Based Opioid Glycopeptides
N. O. Elmagbari, R. Egleton, Michael M. Palian, J. Lowery +10 more
2004Journal of Pharmacology and Experimental Therapeutics57 citations
Semantic Scholar
Biphasic cytoarchitecture and functional changes in the BBB induced by chronic inflammatory pain.
T. Brooks, S. Ocheltree, M. Seelbach, R. Charles +3 more
2006Brain Research56 citations Open access
Semantic Scholar
Transport of opioid peptides into the central nervous system.
R. Egleton, T. Abbruscato, Sarah A. Thomas, T. P. Davis
1998Journal of Pharmacy and Science56 citations
Semantic Scholar
Protection against hypoxia-induced blood-brain barrier disruption: changes in intracellular calcium.
Rachel C. Brown, K. Mark, R. Egleton, T. Davis
2004American Journal of Physiology - Cell Physiology55 citations Open access
Semantic Scholar
Nociceptive inhibition prevents inflammatory pain induced changes in the blood-brain barrier.
Christopher R. Campos, S. Ocheltree, Sharon Hom, R. Egleton +1 more
2008Brain Research39 citations Open access
Semantic Scholar
Biousian glycopeptides penetrate the blood-brain barrier
R. Egleton, E. Bilsky, G. Tollin, M. Dhanasekaran +8 more
200537 citations
Semantic Scholar
Glycopeptides related to beta-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers.
M. Dhanasekaran, Michael M. Palian, I. Alves, Larisa Yeomans +10 more
2005Journal of the American Chemical Society37 citations
Semantic Scholar
The α7-nicotinic acetylcholine receptor and MMP-2/-9 pathway mediate the proangiogenic effect of nicotine in human retinal endothelial cells.
A. Dom, A. Buckley, K. Brown, R. Egleton +6 more
2011Investigative Ophthalmology and Visual Science36 citations Open access
Semantic Scholar
Pharmacodynamic and pharmacokinetic characterization of poly(ethylene glycol) conjugation to met-enkephalin analog [D-Pen2, D-Pen5]-enkephalin (DPDPE).
K. Witt, Jason D. Huber, R. Egleton, M. J. Roberts +5 more
2001Journal of Pharmacology and Experimental Therapeutics36 citations
Semantic Scholar
Assessment of Stereoselectivity of Trimethylphenylalanine Analogues of δ‐Opioid [D‐Pen2,D‐Pen5]‐Enkephalin
K. Witt, C. Slate, R. Egleton, Jason D. Huber +3 more
200034 citations
Semantic Scholar
Differential effects of diabetes on rat choroid plexus ion transporter expression.
R. Egleton, Christopher C. Campos, J. D. Huber, Rachel C. Brown +1 more
2003Diabetes29 citations Open access
Semantic Scholar
Pluronic P85 Block Copolymer Enhances Opioid Peptide Analgesia
K. Witt, J. D. Huber, R. Egleton, T. Davis
2002Journal of Pharmacology and Experimental Therapeutics28 citations
Semantic Scholar
Mechanisms by which Obesity Regulates Inflammation and Anti-tumor Immunity in Cancer
Cora E. Miracle, Chelsea L. McCallister, R. Egleton, Travis B. Salisbury
2024Biochemical and Biophysical Research Communications - BBRC24 citations Open access
Semantic Scholar
Transport of the delta-opioid receptor agonist [D-penicillamine2,5] enkephalin across the blood-brain barrier involves transcytosis1.
R. Egleton, T. P. Davis
1999Journal of Pharmacy and Science24 citations
Semantic Scholar
Effect of reduced flow on blood-brain barrier transport systems.
Sharon Hom, R. Egleton, J. D. Huber, T. Davis
2001Brain Research22 citations
Semantic Scholar
Alterations in Excitatory and Inhibitory Synaptic Development Within the Mesolimbic Dopamine Pathway in a Mouse Model of Prenatal Drug Exposure
Taylor C. Boggess, James C. Williamson, Ethan B. Niebergall, H. Sexton +4 more
2020bioRxiv18 citations Open access
Semantic Scholar
Conjugation of low molecular weight poly(ethylene glycol) to biphalin enhances antinociceptive profile.
J. D. Huber, Christopher R. Campos, R. Egleton, K. Witt +4 more
2003Journal of Pharmacy and Science16 citations
Semantic Scholar
Insulin enhancement of opioid peptide transport across the blood-brain barrier and assessment of analgesic effect.
K. Witt, Jason D. Huber, R. Egleton, T. P. Davis
2000Journal of Pharmacology and Experimental Therapeutics16 citations
Semantic Scholar
Drug abuse and the neurovascular unit.
R. Egleton, T. Abbruscato
2014Advances in Pharmacology14 citations
Semantic Scholar
Peptides at the Blood Brain Barrier: Knowing Me Knowing You
T. Davis, T. Abbruscato, R. Egleton
2015Peptides10 citations Open access
Semantic Scholar
A paradigm shift for evaluating pharmacotherapy for Alzheimer's disease: the 10-patient screening protocol.
J. Weinstein, E. R. Gonzalez, R. Egleton, David A. Hunt
2013The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists10 citations
Semantic Scholar
History of postpartum depression as a contributor to the severity of NAS.
Emma M. Nellhaus, L. Nieuwenhuizen, R. Egleton, Zachary Hansen +3 more
2019Addictive Behaviours7 citations
Semantic Scholar
Development of neuropeptide drugs that cross the blood-brain barrier
R. Egleton, T. Davis
20056 citations Open access
Semantic Scholar
Assessment of stereoselectivity of trimethylphenylalanine analogues of delta-opioid [D-Pen(2),D-Pen(5)]-enkephalin.
K. Witt, C. Slate, R. Egleton, J. D. Huber +3 more
2000Journal of Neurochemistry6 citations
Semantic Scholar
Intake assessments of salivary cortisol, survey responses, and adverse childhood experiences are associated with recovery success in an abstinence-based treatment program for substance use disorders.
Taylor R. Maddox‐Rooper, Kristiana Sklioutouskaya‐Lopez, Trenton Sturgill, Caroline Fresch +4 more
2022Alcoholism: Clinical and Experimental Research5 citations
Semantic Scholar

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