C. J. Dreyton

Most-cited papers

1. Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation

   Xue-Sen Zhang, Michael J. Bolt, Michael J. Guertin, Wei Chen +10 more

   2012Proceedings of the National Academy of Sciences of the United States of America219 citations Open access

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2. Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of Protein Arginine Deiminase 3

   B. Knuckley, Corey P. Causey, Justin Jones, M. Bhatia +4 more

   2010Biochemistry178 citations Open access

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3. Protein Arginine Deiminase 2 Binds Calcium in an Ordered Fashion: Implications for Inhibitor Design

   D. J. Slade, P. Fang, C. J. Dreyton, Ying Zhang +8 more

   2015ACS Chemical Biology122 citations Open access

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4. Chemical Proteomic Platform To Identify Citrullinated Proteins

   Daniel M. Lewallen, Kevin L. Bicker, V. Subramanian, K. Clancy +6 more

   2015ACS Chemical Biology86 citations Open access

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5. Mechanistic Studies of Protein Arginine Deiminase 2: Evidence for a Substrate-Assisted Mechanism

   C. J. Dreyton, B. Knuckley, Justin Jones, Daniel M. Lewallen +1 more

   2014Biochemistry48 citations Open access

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6. Insights into the Mechanism of Streptonigrin-Induced Protein Arginine Deiminase Inactivation

   C. J. Dreyton, Erin D. Anderson, V. Subramanian, D. Boger +1 more

   2014Bioorganic & Medicinal Chemistry31 citations Open access

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7. Mechanistic studies of Agmatine Deiminase from multiple bacterial species

   Justin Jones, C. J. Dreyton, Heather Flick, Corey P. Causey +1 more

   2010Biochemistry19 citations Open access

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8. Optimization and characterization of a pan protein arginine deiminase (PAD) inhibitor

   C. J. Dreyton, Justin Jones, B. Knuckley, Venkatamaran Subramanian +14 more

   201310 citations

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9. Crystal structure of Protein Arginine Deiminase 2 (E354A, 10 mM Ca2+)

   D. J. Slade, Xue-Sen Zhang, P. Fang, C. J. Dreyton +5 more

   20150 citations

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10. Crystal structure of Protein Arginine Deiminase 2 (F221/222A, 10 mM Ca2+)

    D. J. Slade, Xue-Sen Zhang, P. Fang, C. J. Dreyton +5 more

    20150 citations

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11. Crystal structure of Protein Arginine Deiminase 2 (D123N, 10 mM Ca2+)

    D. J. Slade, Xue-Sen Zhang, P. Fang, C. J. Dreyton +5 more

    20150 citations

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12. Crystal structure of Protein Arginine Deiminase 2 (D177A, 10 mM Ca2+)

    D. J. Slade, Xue-Sen Zhang, P. Fang, C. J. Dreyton +5 more

    20150 citations

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13. Crystal structure of Protein Arginine Deiminase 2 (500 uM Ca2

    D. J. Slade, Xue-Sen Zhang, P. Fang, C. J. Dreyton +5 more

    20150 citations

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14. Crystal structure of Protein Arginine Deiminase 2 (50 uM Ca2

    D. J. Slade, Xue-Sen Zhang, P. Fang, C. J. Dreyton +5 more

    20150 citations

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15. Crystal structure of Protein Arginine Deiminase 2 (5 mM Ca2

    D. J. Slade, Xue-Sen Zhang, P. Fang, C. J. Dreyton +5 more

    20150 citations

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16. Crystal structure of Protein Arginine Deiminase 2 (D169A, 10 mM Ca2+)

    D. J. Slade, Xue-Sen Zhang, P. Fang, C. J. Dreyton +5 more

    20150 citations

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17. Figure 2, Preparation of coupling partners A and B

    C. J. Dreyton, Justin Jones, B. Knuckley, Venkatamaran Subramanian +14 more

    20130 citations

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18. Figure 3, IC50 curves for PADs 1–4 with ML325 (SID 118043677) as determined by biochemical substrate assay using the N-α-benzoyl-L-arginine ethyl ester HCl (BAEE) reagent

    C. J. Dreyton, Justin Jones, B. Knuckley, Venkatamaran Subramanian +14 more

    20130 citations

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