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Heiyoung Park · SciRah

Researcher profile · Semantic Scholar

Heiyoung Park

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Heiyoung Park — researcher profile on SciRah

h-index: 23
Works: 41
Citations: 4,004

Most-cited papers

A variant upstream of IFNL3 (IL28B) creating a novel interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus
L. Prokunina-Olsson, Brian Muchmore, Wei-Feng Tang, R. Pfeiffer +20 more
2013Nature Genetics954 citations Open access
Semantic Scholar
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
Ariel C. Bulua, A. Simon, R. Maddipati, Martin Pelletier +5 more
2011Journal of Experimental Medicine856 citations Open access
Semantic Scholar
NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ
Toshiyuki Tanaka, S. Saha, C. Tomomori, R. Ishima +11 more
1998Nature260 citations
Semantic Scholar
Solution structure of the homodimeric core domain of Escherichia coli histidine kinase EnvZ
C. Tomomori, Toshiyuki Tanaka, R. Dutta, Heiyoung Park +9 more
1999Nature Structural Biology247 citations
Semantic Scholar
Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome
A. Simon, Heiyoung Park, R. Maddipati, Adrian A. Lobito +9 more
2010Proceedings of the National Academy of Sciences of the United States of America185 citations Open access
Semantic Scholar
Signal transduction via the histidyl‐aspartyl phosphorelay
L. Egger, Heiyoung Park, M. Inouye
1997Genes to Cells182 citations
Semantic Scholar
Lighting the fires within: the cell biology of autoinflammatory diseases
Heiyoung Park, A. Bourla, D. Kastner, R. Colbert +1 more
2012Nature reviews. Immunology173 citations Open access
Semantic Scholar
Spontaneous clearance of chronic hepatitis C virus infection is associated with appearance of neutralizing antibodies and reversal of T-cell exhaustion.
Sukanya Raghuraman, Heiyoung Park, William O. Osburn, Emily Winkelstein +2 more
2012Journal of Infectious Diseases168 citations Open access
Semantic Scholar
IL-29 Is the Dominant Type III Interferon Produced by Hepatocytes During Acute Hepatitis C Virus Infection
Heiyoung Park, E. Serti, Onyinyechi F. Eke, Brian Muchmore +4 more
2012Hepatology138 citations Open access
Semantic Scholar
Two-domain reconstitution of a functional protein histidine kinase.
Heiyoung Park, S. Saha, M. Inouye
1998Proceedings of the National Academy of Sciences of the United States of America111 citations Open access
Semantic Scholar
Mutational analysis of the linker region of EnvZ, an osmosensor in Escherichia coli
Heiyoung Park, M. Inouye
1997Journal of Bacteriology86 citations Open access
Semantic Scholar
Rapid Decrease in Hepatitis C Viremia by Direct Acting Antivirals Improves the Natural Killer Cell Response to IFNα
E. Serti, Heiyoung Park, M. Keane, Ashley C. O’Keefe +4 more
2016Gut68 citations Open access
Semantic Scholar
Nucleoside-diphosphate Kinase-mediated Signal Transduction via Histidyl-Aspartyl Phosphorelay Systems in Escherichia coli*
Qing Lu, Heiyoung Park, L. Egger, M. Inouye
1996Journal of Biological Chemistry68 citations Open access
Semantic Scholar
New strategies for immunosuppression: interfering with cytokines by targeting the Jak/Stat pathway
J. O'Shea, Heiyoung Park, Marko Pesu, D. Borie +1 more
2005Current Opinion in Rheumatology61 citations Open access
Semantic Scholar
Clearance of pegylated interferon by Kupffer cells limits NK cell activation and therapy response of patients with HBV infection
Akira Nishio, F. Bolte, Kazuyo Takeda, Nana Park +5 more
2021Science Translational Medicine56 citations
Semantic Scholar
During Differentiation of the Monocytic Cell Line U937, Purα Mediates Induction of the CD11c β2 Integrin Gene Promoter1
C. Shelley, J. Teodoridis, Heiyoung Park, O. Farokhzad +2 more
2002Journal of Immunology48 citations
Semantic Scholar
Ligand binding induces an asymmetrical transmembrane signal through a receptor dimer.
Yang Yang, Heiyoung Park, M. Inouye
1993Journal of Molecular Biology45 citations
Semantic Scholar
CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD.
Fotini Nicolaou, J. Teodoridis, Heiyoung Park, A. Georgakis +8 more
2003Blood42 citations
Semantic Scholar
Baseline Intrahepatic and Peripheral Innate Immunity are Associated with Hepatitis C Virus Clearance During DAA Therapy
H. Alao, Maggie Cam, C. Keembiyehetty, Fang Zhang +10 more
2018Hepatology40 citations Open access
Semantic Scholar
The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells
Xian-Gen Li, Jing Xiong, C. Shelley, Heiyoung Park +1 more
2006Development35 citations Open access
Semantic Scholar
The zinc finger transcription factor ZBP-89 is a repressor of the human beta 2-integrin CD11b gene.
Heiyoung Park, C. Shelley, M. Arnaout
2003Blood34 citations Open access
Semantic Scholar
Demonstration of dimer formation of the cytoplasmic domain of a transmembrane osmosensor protein, EnvZ, of Escherichia coli using Ni‐histidine tag affinity chromatography
Yuji Hidaka, Heiyoung Park, M. Inouye
1997FEBS Letters31 citations Open access
Semantic Scholar
During differentiation of the monocytic cell line U937, Pur alpha mediates induction of the CD11c beta 2 integrin gene promoter.
C. Shelley, J. Teodoridis, Heiyoung Park, O. Farokhzad +2 more
2002Journal of Immunology29 citations
Semantic Scholar
The Yersinia Effector Protein YpkA Induces Apoptosis Independently of Actin Depolymerization1
Heiyoung Park, Kabir Teja, J. O'Shea, R. Siegel
2007Journal of Immunology23 citations Open access
Semantic Scholar
Serum neutralization activity declines but memory B cells persist after cure of chronic hepatitis C
Akira Nishio, Sharika Hasan, Heiyoung Park, Nana Park +11 more
2022Nature Communications16 citations Open access
Semantic Scholar
CD43 gene expression is mediated by a nuclear factor which binds pyrimidine-rich single-stranded DNA.
O. Farokhzad, J. Teodoridis, Heiyoung Park, M. Arnaout +1 more
2000Nucleic Acids Research16 citations Open access
Semantic Scholar
Developing a core set of outcome measure domains to study Raynaud's phenomenon and digital ulcers in systemic sclerosis: Report from OMERACT 2020.
N. Maltez, M. Hughes, Edith Brown, Virginia Hickey +6 more
2021Seminars in Arthritis & Rheumatism13 citations Open access
Semantic Scholar
The role of genetics in hepatic fibrosis amongst HCV patients
Heiyoung Park, Thomas R. O'Brien, B. Rehermann
2017Hepatology8 citations Open access
Semantic Scholar
NHLBI Report: Impact of Sex and Gender on Autoimmune Lung Disease, Opportunities for Future Research.
E. Volkmann, J. Siegfried, T. Lahm, Corey E. Ventetuolo +18 more
2022American Journal of Respiratory and Critical Care Medicine5 citations Open access
Semantic Scholar
182 : Identification and characterization of interferon-λ4 (IFN-λ4), a novel class-2 cytokine which impairs clearance of hepatitis C virus
Brian Muchmore, Wei-Feng Tang, P. Porter-Gill, I. Kohaar +9 more
20132 citations
Semantic Scholar
Reactive Oxygen Species Support the Normal Inflammatory Process and Promote Pathological Inflammation in the TNF ReceptorAssociated Periodic Syndrome (TRAPS)
Ariel C. Bulua, Martin Pelletier, A. Simon, R. Maddipati +3 more
20102 citations
Semantic Scholar
Insights into autoimmunity and cancer
Xin-Rui Li, Carmen Ufret-Vincenty, Jacqueline Robinson-Hamm, Lillian Kuo +2 more
2025Nature Immunology1 citations
Semantic Scholar
Title A variant upstream of IFNL 3 ( IL 28 B ) creating a novel interferon gene IFNL 4 is associated with impaired clearance of hepatitis C virus
L. Prokunina-Olsson, Brian Muchmore, Wei-Feng Tang, R. Pfeiffer +20 more
20131 citations
Semantic Scholar
Gene Promoter 2 CD11c Mediates Induction of the a Line U937, Pur During Differentiation of the Monocytic Cell
C. Farokhzad, E. Böttinger, M. Arnaout, C. Shelley +2 more
20021 citations
Semantic Scholar
Transcriptome analysis reveals distinct immune response profiles in HBeAg+ and HBeAg− HBV infection and in HBV/HDV co-infection
Heiyoung Park, T. Heller, B. Rehermann
2017Journal of Immunology0 citations
Semantic Scholar
Development of genetically engineered TCR-transduced T cells for immunotherapy of chronic hepatitis B and C virus infections (P4222)
Su-Hyung Park, Heiyoung Park, Warren W Pan, B. Rehermann
2013Journal of Immunology0 citations
Semantic Scholar
Faculty Opinions recommendation of Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response.
B. Rehermann, Heiyoung Park
20120 citations
Semantic Scholar
Abstract 3751: Expression analysis of the IL28A, IL28B, IL29 and IL28L genes in primary human peripheral blood mononuclear cells and hepatocytes: Effects of activation mode, time-course and genotypes
Brian Muchmore, Heiyoung Park, H. Dickensheets, T. O'Brien +3 more
20110 citations
Semantic Scholar
Intracellular accumulation of mutant TNFR1 potentiates MAP‐Kinase signaling and innate immune responses in the TNF‐receptor associated Periodic Syndrome (TRAPS)
Heiyoung Park, A. Simon, R. Maddipati, Ariel C. Bulua +3 more
20080 citations
Semantic Scholar
141 Mutated TNF-receptor Type 1 in TNF-receptor Associated Periodic Syndrome (TRAPS): TNF-Independent Hyper-responsiveness Through ER-retained, Misfolded Receptors
A. Simon, Ravikanth Maddipatti, Heiyoung Park, H. Komarow +2 more
20070 citations
Semantic Scholar
NMRstructureof thehistidine kinasedomainof the E . coli osmosensorEnvZ
Toshiyuki Tanaka, S. Saha, C. Tomomori, R. Ishima +11 more
0 citations
Semantic Scholar

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