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Celine Eidenschenk · SciRah

Researcher profile · Semantic Scholar

Celine Eidenschenk

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Celine Eidenschenk — researcher profile on SciRah

h-index: 35
Works: 55
Citations: 6,285

Most-cited papers

Herpes Simplex Virus Encephalitis in Human UNC-93B Deficiency
A. Casrouge, Shen-Ying Zhang, Celine Eidenschenk, E. Jouanguy +24 more
2006Science745 citations
Semantic Scholar
Impaired response to interferon-α/β and lethal viral disease in human STAT1 deficiency
S. Dupuis, E. Jouanguy, Sami Al-Hajjar, C. Fieschi +14 more
2003Nature Genetics548 citations
Semantic Scholar
Interleukin-22 alleviates metabolic disorders and restores mucosal immunity in diabetes
Xiaoting Wang, Naruhisa Ota, P. Manzanillo, L. Kates +10 more
2014Nature472 citations
Semantic Scholar
IL‐22, not simply a Th17 cytokine
S. Rutz, Celine Eidenschenk, W. Ouyang
2013Immunological Reviews448 citations
Semantic Scholar
Impaired response to interferon-alpha/beta and lethal viral disease in human STAT1 deficiency.
S. Dupuis, E. Jouanguy, Sami Al-Hajjar, C. Fieschi +14 more
2003Nature Genetics399 citations
Semantic Scholar
Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency.
Laure Gineau, C. Cognet, Nihan Kara, Francis P. Lach +16 more
2012Journal of Clinical Investigation280 citations Open access
Semantic Scholar
Human TLR-7-, -8-, and -9-Mediated Induction of IFN-α/β and -λ Is IRAK-4 Dependent and Redundant for Protective Immunity to Viruses
Kun Yang, A. Puel, Shen-Ying Zhang, Celine Eidenschenk +24 more
2005Immunity278 citations Open access
Semantic Scholar
NRROS negatively regulates reactive oxygen species during host defence and autoimmunity
R. Noubade, Kit Wong, Naruhisa Ota, S. Rutz +13 more
2014Nature243 citations
Semantic Scholar
Genetic analysis of resistance to viral infection
B. Beutler, Celine Eidenschenk, K. Crozat, J. Imler +3 more
2007Nature reviews. Immunology209 citations
Semantic Scholar
Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells
S. Rutz, R. Noubade, Celine Eidenschenk, Naruhisa Ota +6 more
2011Nature Immunology206 citations
Semantic Scholar
A novel immunodeficiency associated with hypomorphic RAG1 mutations and CMV infection.
J. de Villartay, A. Lim, H. Al-Mousa, S. Dupont +10 more
2005Journal of Clinical Investigation194 citations Open access
Semantic Scholar
Interleukin-22 induces interleukin-18 expression from epithelial cells during intestinal infection.
M. Muñoz, Celine Eidenschenk, Naruhisa Ota, Kit Wong +13 more
2015Immunity181 citations Open access
Semantic Scholar
c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis
C. Neumann, Jonas Blume, Urmi Roy, Peggy P. Teh +23 more
2019Nature Immunology160 citations Open access
Semantic Scholar
Fatal varicella associated with selective natural killer cell deficiency.
Amos Etzioni, Celine Eidenschenk, R. Katz, Rafeal Beck +2 more
2005Jornal de Pediatria151 citations
Semantic Scholar
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
B. Croker, B. Lawson, S. Rutschmann, Michael Berger +9 more
2008Proceedings of the National Academy of Sciences of the United States of America135 citations Open access
Semantic Scholar
Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency
J. Cottineau, Molly C. Kottemann, Francis P. Lach, Young-Hoon Kang +38 more
2017Journal of Clinical Investigation127 citations Open access
Semantic Scholar
Deubiquitinase DUBA is a post-translational brake on interleukin-17 production in T cells
S. Rutz, N. Kayagaki, Q. Phung, Celine Eidenschenk +17 more
2014Nature124 citations
Semantic Scholar
A novel primary immunodeficiency with specific natural-killer cell deficiency maps to the centromeric region of chromosome 8.
Celine Eidenschenk, J. Dunne, E. Jouanguy, Claire Fourlinnie +7 more
2006American Journal of Human Genetics124 citations Open access
Semantic Scholar
Disruption of XIAP-RIP2 Association Blocks NOD2-Mediated Inflammatory Signaling.
Tatiana Goncharov, Stefanie Hedayati, Melinda M. Mulvihill, A. Izrael-Tomasevic +11 more
2018Molecules and Cells112 citations Open access
Semantic Scholar
Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery
M. Barnes, P. Krebs, N. Harris, Celine Eidenschenk +8 more
2009PLoS Biology110 citations Open access
Semantic Scholar
Role of IL-22 in microbial host defense.
Celine Eidenschenk, S. Rutz, O. Liesenfeld, W. Ouyang
2014Current Topics in Microbiology and Immunology89 citations
Semantic Scholar
Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action.
Olivier René, Ben Fauber, G. Boenig, Brenda Burton +12 more
2015ACS Medicinal Chemistry Letters77 citations Open access
Semantic Scholar
Targeted alveolar regeneration with Frizzled-specific agonists.
A. Nabhan, J. Webster, Jarrett J. Adams, Levi L. Blazer +13 more
2023Cell72 citations Open access
Semantic Scholar
Discovery of imidazo[1,5-a]pyridines and -pyrimidines as potent and selective RORc inverse agonists.
Ben Fauber, A. Gobbi, K. Robarge, Aihe Zhou +15 more
2015Bioorganic & Medicinal Chemistry Letters63 citations Open access
Semantic Scholar
Post-translational regulation of RORγt-A therapeutic target for the modulation of interleukin-17-mediated responses in autoimmune diseases.
S. Rutz, Celine Eidenschenk, J. Kiefer, W. Ouyang
2016Cytokine & growth factor reviews61 citations Open access
Semantic Scholar
Structure-based design of substituted hexafluoroisopropanol-arylsulfonamides as modulators of RORc.
Ben Fauber, Gladys De Leon Boenig, Brenda Burton, Celine Eidenschenk +10 more
2013Bioorganic & Medicinal Chemistry Letters60 citations Open access
Semantic Scholar
Discovery of 1-{4-[3-fluoro-4-((3s,6r)-3-methyl-1,1-dioxo-6-phenyl-[1,2]thiazinan-2-ylmethyl)-phenyl]-piperazin-1-yl}-ethanone (GNE-3500): a potent, selective, and orally bioavailable retinoic acid receptor-related orphan receptor C (RORc or RORγ) inverse agonist.
Ben Fauber, Olivier René, Yuzhong Deng, J. DeVoss +13 more
2015Journal of Medicinal Chemistry55 citations
Semantic Scholar
Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells
Celine Eidenschenk, K. Crozat, P. Krebs, R. Arens +7 more
2010Proceedings of the National Academy of Sciences of the United States of America55 citations Open access
Semantic Scholar
Reduction in lipophilicity improved the solubility, plasma-protein binding, and permeability of tertiary sulfonamide RORc inverse agonists.
Ben Fauber, Olivier René, Gladys De Leon Boenig, Brenda Burton +13 more
2014Bioorganic & Medicinal Chemistry Letters49 citations Open access
Semantic Scholar
ENU-induced phenovariance in mice: inferences from 587 mutations
Carrie N. Arnold, M. Barnes, Michael Berger, A. Blasius +27 more
2012BMC Research Notes45 citations Open access
Semantic Scholar
A novel developmental and immunodeficiency syndrome associated with intrauterine growth retardation and a lack of natural killer cells.
F. Bernard, C. Picard, V. Cormier-Daire, Celine Eidenschenk +11 more
2004Pediatrics42 citations
Semantic Scholar
Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity
R. Barreira da Silva, Ricardo M. Leitao, Ximo Pechuan-Jorge, S. Werneke +21 more
2022Nature Immunology41 citations Open access
Semantic Scholar
Increased Susceptibility to DNA Virus Infection in Mice with a GCN2 Mutation
Sungyong Won, Celine Eidenschenk, Carrie N. Arnold, O. Siggs +6 more
2011Journal of Virology39 citations Open access
Semantic Scholar
Deciphering the crosstalk among IL-1 and IL-10 family cytokines in intestinal immunity.
P. Manzanillo, Celine Eidenschenk, W. Ouyang
2015Trends in immunology38 citations
Semantic Scholar
Familial NK Cell Deficiency Associated with Impaired IL-2- and IL-15-Dependent Survival of Lymphocytes1
Celine Eidenschenk, E. Jouanguy, A. Alcaïs, Jean-Jacques Mention +8 more
2006Journal of Immunology35 citations Open access
Semantic Scholar
A reversed sulfonamide series of selective RORc inverse agonists.
M. B. Van Niel, Ben Fauber, Matthew W. Cartwright, S. Gaines +21 more
2014Bioorganic & Medicinal Chemistry Letters33 citations Open access
Semantic Scholar
Tumor suppressor BAP1 is essential for thymic development and proliferative responses of T lymphocytes
Teresita L. Arenzana, Steve Lianoglou, A. Seki, Celine Eidenschenk +19 more
2018Science immunology32 citations Open access
Semantic Scholar
The Tpl2 mutation Sluggish impairs type I interferon production and increases susceptibility to group B streptococcal disease
Neng-Ming Xiao, Celine Eidenschenk, P. Krebs, Katharina Brandl +5 more
2009Journal of Immunology31 citations Open access
Semantic Scholar
Design and Evaluation of Highly-Selective Human Immunoproteasome Inhibitors Reveals a Compensatory Process that Preserves Immune Cell Viability.
Ena Ladi, Christine Everett, C. Stivala, Blake E Daniels +11 more
2019Journal of Medicinal Chemistry30 citations
Semantic Scholar
Impact of β2 integrin deficiency on mouse natural killer cell development and function.
K. Crozat, Celine Eidenschenk, Baptiste N. Jaeger, P. Krebs +4 more
2011Blood28 citations Open access
Semantic Scholar
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
O. Siggs, Michael Berger, P. Krebs, Carrie N. Arnold +10 more
2010Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
Ru(II)-diimine complexes and cytochrome P450 working hand-in-hand
Celine Eidenschenk, Lionel Cheruzel
2020Journal of Inorganic Biochemistry14 citations Open access
Semantic Scholar
Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties.
Olivier René, Ben Fauber, A. Barnard, K. Chapman +10 more
2016Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Transport of LDL-derived cholesterol from the NPC 1 compartment to the ER involves the trans-Golgi network and the SNARE protein complex
B. Croker, B. Lawson, S. Rutschmann, Michael Berger +12 more
20088 citations
Semantic Scholar
The Tpl 2 Mutation Sluggish Impairs Type I IFN Production and Increases Susceptibility to Group B Streptococcal Disease 1
Neng-Ming Xiao, Celine Eidenschenk, P. Krebs, Katharina Brandl +5 more
20094 citations
Semantic Scholar
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, 39, (15028-15033) DOI: 10.1073/pnas.0806619105)
B. Croker, B. Lawson, S. Rutschmann, Michael Berger +9 more
20084 citations Open access
Semantic Scholar
The IL-20 Subfamily of Cytokines and Their Receptors
S. Rutz, Xiaoting Wang, Celine Eidenschenk, Naruhisa Ota +1 more
20162 citations
Semantic Scholar
TGF-{beta}-dependent suppression of IL-22 production in TH17 cells is mediated by the transcription factor c-Maf
S. Rutz, R. Noubade, Celine Eidenschenk, Harinder Singh +1 more
20122 citations
Semantic Scholar
Ultrastructure et distribution tissulaire du virus C de la drosophile (DCV)
Catherine Dostert, E. Jouanguy, Celine Eidenschenk, F. Jousset +2 more
20032 citations
Semantic Scholar
ENU-induced phenovariance in mice: inferences from 587 mutations
Carrie N. Arnold, Michael J. Barnes, Michael Berger, A. Blasius +27 more
2012BMC Research Notes1 citations Open access
Semantic Scholar

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