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D. Calne · SciRah

Researcher profile · Semantic Scholar

D. Calne

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D. Calne — researcher profile on SciRah

h-index: 92
Works: 504
Citations: 39K

Most-cited papers

Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
A. Zimprich, S. Biskup, Petra Leitner, P. Lichtner +18 more
2004Neuron3,084 citations Open access
Semantic Scholar
Expectation and Dopamine Release: Mechanism of the Placebo Effect in Parkinson's Disease
R. de la Fuente-Fernández, T. J. Ruth, V. Sossi, M. Schulzer +2 more
2001Science1,001 citations
Semantic Scholar
In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease
Chong S. Lee, A. Samii, V. Sossi, Thomas J. Ruth +7 more
2000Annals of Neurology598 citations
Semantic Scholar
Manganese neurotoxicity: a review of clinical features, imaging and pathology.
P. Pal, A. Samii, D. Calne
1999Neurotoxicology446 citations
Semantic Scholar
Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias.
R. de la Fuente-Fernández, V. Sossi, Zhi-Gao Huang, S. Furtado +4 more
2004Brain : a journal of neurology416 citations Open access
Semantic Scholar
Levodopa in the treatment of Parkinson's disease: A consensus meeting viewpoint
Y. Agid, E. Ahlskog, A. Albanese, D. Calne +26 more
1999Movement Disorders390 citations
Semantic Scholar
Dopamine release in human ventral striatum and expectation of reward.
R. de la Fuente-Fernández, A. Phillips, M. Zamburlini, V. Sossi +3 more
2002Behavioural Brain Research328 citations
Semantic Scholar
DCTN1 mutations in Perry syndrome
M. Farrer, M. Hulihan, J. Kachergus, J. Dächsel +18 more
2009Nature Genetics320 citations Open access
Semantic Scholar
Autosomal dominant parkinsonism associated with variable synuclein and tau pathology
Z. Wszolek, R. F. Pfeiffer, Y. Tsuboi, R. Uitti +9 more
2004Neurology273 citations
Semantic Scholar
PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation.
John R. Adams, Hinke van Netten, M. Schulzer, E. Mak +11 more
2005Brain : a journal of neurology269 citations Open access
Semantic Scholar
Longitudinal progression of sporadic Parkinson's disease: a multi-tracer positron emission tomography study.
R. Nandhagopal, L. Kuramoto, M. Schulzer, E. Mak +11 more
2009Brain : a journal of neurology255 citations
Semantic Scholar
Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover.
R. de la Fuente-Fernández, Jian-Qiang Lu, V. Sossi, S. Jivan +6 more
2001Annals of Neurology241 citations
Semantic Scholar
Age‐specific progression of nigrostriatal dysfunction in Parkinson's disease
R. de la Fuente-Fernández, M. Schulzer, L. Kuramoto, J. Cragg +10 more
2011Annals of Neurology225 citations
Semantic Scholar
The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval.
A. Zimprich, B. Müller-Myhsok, M. Farrer, Petra Leitner +17 more
2004American Journal of Human Genetics215 citations Open access
Semantic Scholar
Botulinum toxin A as treatment for drooling saliva in PD
P. Pal, D. Calne, S. Calne, J. Tsui
2000Neurology209 citations
Semantic Scholar
Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover
R. de la Fuente-Fernández, Jian-Qiang Lu, V. Sossi, S. Jivan +6 more
2001178 citations
Semantic Scholar
Profile of families with parkinsonism‐predominant spinocerebellar ataxia type 2 (SCA2)
S. Furtado, H. Payami, P. Lockhart, M. Hanson +16 more
2004Movement Disorders130 citations
Semantic Scholar
Presynaptic mechanisms of motor fluctuations in Parkinson's disease: a probabilistic model.
R. de la Fuente-Fernández, M. Schulzer, E. Mak, D. Calne +1 more
2004Brain : a journal of neurology122 citations Open access
Semantic Scholar
PET studies of parkinsonism associated with mutation in the alpha-synuclein gene.
A. Samii, K. Markopoulou, Z. Wszolek, V. Sossi +4 more
1999Neurology117 citations
Semantic Scholar
Pallidonigral TDP-43 pathology in Perry syndrome
C. Wider, D. Dickson, A. Stoessl, Y. Tsuboi +15 more
2008Parkinsonism & Related Disorders112 citations Open access
Semantic Scholar
Genetic heterogeneity in familial idiopathic basal ganglia calcification (Fahr disease)
J. Oliveira, E. Spiteri, M. Sobrido, S. Hopfer +11 more
2004Neurology110 citations Open access
Semantic Scholar
Nigrostriatal dopamine system and motor lateralization.
R. de la Fuente-Fernández, A. Kishore, D. Calne, Thomas J. Ruth +1 more
2000Behavioural Brain Research93 citations
Semantic Scholar
Pattern of dopaminergic loss in the striatum of humans with MPTP induced parkinsonism
B. Snow, F. Vingerhoets, J. Langston, J. Tetrud +2 more
2000Journal of Neurology Neurosurgery & Psychiatry92 citations Open access
Semantic Scholar
Occupational risk factors in Parkinson's disease.
J. Tsui, D. Calne, Yue Wang, M. Schulzer +1 more
1999Canadian journal of public health82 citations
Semantic Scholar
Identification of a novel risk locus for progressive supranuclear palsy by a pooled genomewide scan of 500,288 single-nucleotide polymorphisms.
S. Melquist, David W. Craig, M. Huentelman, R. Crook +24 more
2007American Journal of Human Genetics74 citations Open access
Semantic Scholar
Severe vascular disturbance in a case of familial brain calcinosis
J. Miklossy, I. Mackenzie, K. Dorovini-Zis, D. Calne +3 more
2005Acta Neuropathologica73 citations
Semantic Scholar
SCA-2 presenting as parkinsonism in an Alberta family
S. Furtado, M. Farrer, Y. Tsuboi, M. Klimek +7 more
2002Neurology73 citations
Semantic Scholar
VMAT2 binding is elevated in dopa‐responsive dystonia: Visualizing empty vesicles by PET
R. de la Fuente-Fernández, S. Furtado, M. Guttman, Y. Furukawa +4 more
2003Synapse72 citations
Semantic Scholar
Evidence for impaired presynaptic dopamine function in parkinsonian patients with motor fluctuations
R. de la Fuente-Fernández, P. K. Pal, F. Vingerhoets, A. Kishore +6 more
2000Journal of neural transmission70 citations
Semantic Scholar
Unilateral pallidotomy for reduction of parkinsonian pain.
Christopher R. Honey, A. Stoessl, J. Tsui, M. Schulzer +1 more
1999Journal of Neurosurgery68 citations Open access
Semantic Scholar
Reassessment of unilateral pallidotomy in Parkinson's disease. A 2-year follow-up study.
A. Samii, I. Turnbull, A. Kishore, M. Schulzer +3 more
1999Brain : a journal of neurology67 citations
Semantic Scholar
SLC20A2 and THAP1 deletion in familial basal ganglia calcification with dystonia
M. Baker, A. Strongosky, Monica Sanchez-Contreras, Shan Yang +11 more
2013Neurogenetics63 citations Open access
Semantic Scholar
The neuromythology of Parkinson's Disease.
D. Calne, Y. Mizuno
2004Parkinsonism & Related Disorders63 citations
Semantic Scholar
Reproducibility studies with 11C-DTBZ, a monoamine vesicular transporter inhibitor in healthy human subjects.
G. Chan, J. E. Holden, A. Stoessl, Ali Samii +7 more
1999Journal of Nuclear Medicine62 citations
Semantic Scholar
Transdermal dopaminergic D2 receptor agonist therapy in Parkinson's disease with N‐0923 TDS: A double‐blind, placebo‐controlled study
J. Hutton, L. Metman, T. Chase, J. Juncos +11 more
200161 citations
Semantic Scholar
Lack of regional selectivity during the progression of Parkinson disease: implications for pathogenesis.
Chong S. Lee, M. Schulzer, R. de la Fuente-Fernández, E. Mak +5 more
2004Archives of Neurology59 citations Open access
Semantic Scholar
Apomorphine-Induced Changes in Synaptic Dopamine Levels: Positron Emission Tomography Evidence for Presynaptic Inhibition
R. de la Fuente-Fernández, Andrew S. Lim, V. Sossi, J. E. Holden +3 more
2001Journal of Cerebral Blood Flow and Metabolism58 citations Open access
Semantic Scholar
Striatal D2 receptors in symptomatic and asymptomatic carriers of dopa-responsive dystonia measured with [11C]-raclopride and positron-emission tomography
A. Kishore, T. Nygaard, R. de la Fuente-Fernández, A. Naini +6 more
1998Neurology52 citations
Semantic Scholar
The long-term response to levodopa in dopa-responsive dystonia.
W. Hwang, D. Calne, J. Tsui, R. de la Fuente-Fernández
2001Parkinsonism & Related Disorders51 citations
Semantic Scholar
A definition of Parkinson's disease.
D. Calne
2005Parkinsonism & Related Disorders49 citations
Semantic Scholar
Determination of an Occupational Exposure Guideline for Manganese Using the Benchmark Method
H. Clewell, G. Lawrence, D. Calne, Kenny S. Crump
2003Risk Analysis47 citations
Semantic Scholar
Long term outcome of unilateral pallidotomy: follow up of 15 patients for 3 years
P. Pal, A. Samii, A. Kishore, M. Schulzer +4 more
2000Journal of Neurology Neurosurgery & Psychiatry47 citations Open access
Semantic Scholar
The natural history of neurological manganism over 18 years.
Chin-Chang Huang, N.-S. Chu, C. Lu, Rou-shayn Chen +2 more
2007Parkinsonism & Related Disorders46 citations
Semantic Scholar
Clinical presentation of primary progressive multiple sclerosis 10 years after the incidental finding of typical magnetic resonance imaging brain lesions
G. McDonnell, J. Cabrera-Gomez, D. Calne, D. Li +1 more
2003Multiple Sclerosis46 citations
Semantic Scholar
Daytime somnolence in patients with Parkinson's disease.
C. C. Sanjiv, M. Schulzer, E. Mak, J. Fleming +7 more
2001Parkinsonism & Related Disorders44 citations
Semantic Scholar
Parkinson's disease is not one disease.
D. Calne
2000Parkinsonism & Related Disorders44 citations
Semantic Scholar
Drugs for the Treatment of Parkinson’s Disease
D. Calne
2011Handbook of Experimental Pharmacology42 citations
Semantic Scholar
Evidence for environmental causation of Parkinson's disease.
R. de la Fuente-Fernández, D. Calne
2002Parkinsonism & Related Disorders42 citations
Semantic Scholar
Further observations on Tau-positive glia in the brains with progressive supranuclear palsy
T. Yamada, D. Calne, H. Akiyama, E. Mcgeer +1 more
2004Acta Neuropathologica40 citations
Semantic Scholar
Clustering of Parkinson disease: shared cause or coincidence?
Ajit Kumar, Susan M. Calne, M. Schulzer, E. Mak +5 more
2004Archives of Neurology40 citations Open access
Semantic Scholar

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A. Stoessl×28
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A. Stoessl — researcher profile on SciRah
R. de la Fuente-Fernández×19
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R. de la Fuente-Fernández — researcher profile on SciRah
M. Schulzer×14
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M. Schulzer — researcher profile on SciRah
V. Sossi×13
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V. Sossi — researcher profile on SciRah

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E. Mak — researcher profile on SciRah

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Z. Wszolek — researcher profile on SciRah

Thomas J. Ruth×10

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Thomas J. Ruth — researcher profile on SciRah

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M. Farrer — researcher profile on SciRah

Chong S. Lee×7

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Chong S. Lee — researcher profile on SciRah

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A. Samii — researcher profile on SciRah

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D. Dickson — researcher profile on SciRah

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T. J. Ruth — researcher profile on SciRah