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Casey D. Johnson · SciRah

Researcher profile · Semantic Scholar

Casey D. Johnson

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Casey D. Johnson — researcher profile on SciRah

h-index: 22
Works: 43
Citations: 4,394

Most-cited papers

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
Auvro R. Mridha, A. Wree, A. Robertson, Matthew M. Yeh +11 more
2017Journal of Hepatology1,042 citations Open access
Semantic Scholar
NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation and fibrosis
A. Wree, Akiko Eguchi, Matthew D. McGeough, C. Peña +4 more
2014Hepatology857 citations Open access
Semantic Scholar
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis
S. Gaul, A. Leszczyńska, F. Alegre, B. Kaufmann +14 more
2020Journal of Hepatology517 citations Open access
Semantic Scholar
NLRP3 inflammasome driven liver injury and fibrosis: roles of IL- 17 and TNF
A. Wree, Matthew D. McGeough, M. Inzaugarat, Akiko Eguchi +7 more
2017Hepatology257 citations Open access
Semantic Scholar
Circulating Extracellular Vesicles with Specific Proteome and Liver MicroRNAs Are Potential Biomarkers for Liver Injury in Experimental Fatty Liver Disease
D. Povero, Akiko Eguchi, Hongying Li, Casey D. Johnson +4 more
2014PLoS ONE254 citations Open access
Semantic Scholar
Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223.
C. J. Calvente, M. Tameda, Casey D. Johnson, Hana del Pilar +6 more
2019Journal of Clinical Investigation231 citations Open access
Semantic Scholar
Lipid-Induced Hepatocyte-Derived Extracellular Vesicles Regulate Hepatic Stellate Cells via MicroRNA Targeting Peroxisome Proliferator-Activated Receptor-γ
D. Povero, N. Panera, Akiko Eguchi, Casey D. Johnson +6 more
2015Cellular and Molecular Gastroenterology and Hepatology190 citations Open access
Semantic Scholar
TNF regulates transcription of NLRP3 inflammasome components and inflammatory molecules in cryopyrinopathies
Matthew D. McGeough, A. Wree, M. Inzaugarat, Ariela Haimovich +6 more
2017Journal of Clinical Investigation157 citations Open access
Semantic Scholar
NLRP3 inflammasome activation in hepatic stellate cells induces murine liver fibrosis
M. Inzaugarat, Casey D. Johnson, T. Holtmann, Matthew D. McGeough +6 more
2019Hepatology129 citations Open access
Semantic Scholar
MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver Injury.
Carolina Jimenez Calvente, Hana Del Pilar, M. Tameda, Casey D. Johnson +1 more
2020Molecular Therapy104 citations Open access
Semantic Scholar
Differential activation of hepatic iNKT cell subsets plays a key role in progression of nonalcoholic steatohepatitis
I. Maričić, I. Marrero, Akiko Eguchi, Ryota Nakamura +9 more
2018Journal of Immunology90 citations Open access
Semantic Scholar
Oxidized linoleic acid metabolites induce liver mitochondrial dysfunction, apoptosis, and NLRP3 activation in mice[S]
Susanne Schuster, Casey D. Johnson, Marie Hennebelle, T. Holtmann +7 more
2018Journal of Lipid Research81 citations Open access
Semantic Scholar
ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model.
Susanne Schuster-Gaul, Lukas Geisler, Matthew D. McGeough, Casey D. Johnson +10 more
2020JCI Insight72 citations Open access
Semantic Scholar
A Low ω-6 to ω-3 PUFA Ratio (n–6:n–3 PUFA) Diet to Treat Fatty Liver Disease in Obese Youth
M. V. Van Name, M. Savoye, J. Chick, Brittany T Galuppo +9 more
2020Journal of NutriLife64 citations Open access
Semantic Scholar
Redox nanoparticles as a novel treatment approach for inflammation and fibrosis associated with nonalcoholic steatohepatitis.
Akiko Eguchi, Toru Yoshitomi, M. Lazić, Casey D. Johnson +6 more
2015Nanomedicine50 citations Open access
Semantic Scholar
Skeletal muscle-specific overexpression of SIRT1 does not enhance whole-body energy expenditure or insulin sensitivity in young mice
Amanda T. White, C. McCurdy, Andrew Philp, D. Hamilton +2 more
2013Diabetologia48 citations Open access
Semantic Scholar
Liver Bid-suppression for treatment of fibrosis associated with nonalcoholic steatohepatitis
Akiko Eguchi, Xavier De Mollerat Du Jeu, Casey D. Johnson, Andronikou Nektaria +1 more
2015Journal of Hepatology45 citations Open access
Semantic Scholar
Effects of diets enriched in linoleic acid and its peroxidation products on brain fatty acids, oxylipins, and aldehydes in mice
C. Ramsden, Marie Hennebelle, Susanne Schuster, Gregory S. Keyes +11 more
2018Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids36 citations Open access
Semantic Scholar
Oxidized Derivatives of Linoleic Acid in Pediatric Metabolic Syndrome: Is Their Pathogenic Role Modulated by the Genetic Background and the Gut Microbiota?
Domenico Tricò, A. Di Sessa, S. Caprio, N. Chalasani +8 more
2017Antioxidants and Redox Signaling36 citations Open access
Semantic Scholar
Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation
A. Wree, Casey D. Johnson, Joan Font-Burgada, Akiko Eguchi +3 more
2015Cell Death and Differentiation31 citations Open access
Semantic Scholar
Emricasan, a pan caspase inhibitor, improves survival and portal hypertension in a murine model of common bile-duct ligation
Akiko Eguchi, Y. Koyama, A. Wree, Casey D. Johnson +7 more
2018Journal of molecular medicine28 citations Open access
Semantic Scholar
JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders
Géza Ambrus-Aikelin, K. Takeda, A. Joetham, M. Lazic +15 more
2023Scientific Reports26 citations Open access
Semantic Scholar
Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein levels predict the presence of fibrotic nonalcoholic steatohepatitis (NASH) and NASH cirrhosis
N. Alkhouri, Casey D. Johnson, L. Adams, S. Kitajima +6 more
2018PLoS ONE20 citations Open access
Semantic Scholar
Differential regulation of inflammation and apoptosis in Fas-resistant hepatocyte-specific Bid-deficient mice
M. Lazić, Akiko Eguchi, M. Berk, D. Povero +4 more
2014Journal of Hepatology14 citations Open access
Semantic Scholar
Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis
D. Povero, M. Lazic, Christopher McBride, Géza Ambrus-Aikelin +10 more
2023Journal of Pharmacology and Experimental Therapeutics11 citations
Semantic Scholar
Apoptosis signal-regulating kinase 1 (ASK1) inhibition reduces liver fibrosis and apoptosis in a NLRP3 mutant model of NASH
Susanne Schuster, Matthew D. McGeough, Casey D. Johnson, A. Zagórska +3 more
20175 citations
Semantic Scholar
Feeding mice a diet high in oxidized linoleic acid metabolites does not alter liver oxylipin concentrations
Nuanyi Liang, Marie Hennebelle, S. Gaul, Casey D. Johnson +6 more
2021Prostaglandins, Leukotrienes and Essential Fatty Acids3 citations Open access
Semantic Scholar
Direct activation of Nlrp3 inflammasome in hepatic stellate cells leads to upregulation of fibrotic markers
M. Inzaugarat, Matthew D. McGeough, T. Holtmann, M. Frissen +5 more
20173 citations
Semantic Scholar
Correction: Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein levels predict the presence of fibrotic nonalcoholic steatohepatitis (NASH) and NASH cirrhosis
N. Alkhouri, Casey D. Johnson, L. Adams, S. Kitajima +6 more
2018PLoS ONE2 citations Open access
Semantic Scholar
Discovery of Inhibitors of NLRP3 inflammasome assembly for the treatment of NASH and liver fibrosis
J. Veal, C. McBride, M. Lazić, D. Povero +7 more
20181 citations
Semantic Scholar
75 HEPATOCYTE-DERIVED MICROPARTICLES WITH A SPECIFIC ANTIGENIC COMPOSITION ARE RELEASED IN BLOOD DURING NASH DEVELOPMENT: IMPLICATIONS FOR BIOMARKERS DEVELOPMENT
D. Povero, Akiko Eguchi, Casey D. Johnson, A. Wree +3 more
20131 citations Open access
Semantic Scholar
Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders
Géza Ambrus-Aikelin, K. Takeda, A. Joetham, M. Lazic +15 more
2023Scientific Reports0 citations Open access
Semantic Scholar
764 – Protein and Mirna Profiling of Circulating Extracellular Vesicles in Patients with Primary Sclerosing Cholangitis
M. Tameda, D. Povero, M. Kanazawa, Casey D. Johnson +6 more
2019Gastroenterology0 citations Open access
Semantic Scholar
NLRP3 inflammasome activation in hepatocytes results in pyroptotic cell death, release of NLRP3 particles and liver fibrosis
Susanne Schuster, F. Guerra, Casey D. Johnson, C. J. Calvente +6 more
20180 citations
Semantic Scholar
Induced pluripotent stem cells-derived extracellular vesicles shuttle bioactive molecules with anti-fibrotic potential in vitro and in vivo
D. Povero, Eva M. Pinatel, Jihoon Kim, Nidhi P Goyal +3 more
20170 citations
Semantic Scholar
Tu2045 Loss of Hepatocyte-Specific Vascular Endothelial Growth Factor Accelerates Fibrosis in Non-Alcoholic Steatohepatitis
Daphne S. Say, D. Povero, Akiko Eguchi, Casey D. Johnson +1 more
20150 citations
Semantic Scholar
CDAA resembles the histopathological features of human NASH.
D. Povero, Akiko Eguchi, Hongying Li, Casey D. Johnson +4 more
20140 citations Open access
Semantic Scholar
132 NLRP3-INFLAMMASOME ACTIVATION IS ESSENTIAL FOR PROGRESSION TO STEATOHEPATITIS AND FIBROSIS
A. Wree, Matthew D. McGeough, Akiko Eguchi, Casey D. Johnson +4 more
20130 citations Open access
Semantic Scholar
OC-10 Hepatocyte-derived microparticles released in blood as biomarkers of NASH development
D. Povero, Akiko Eguchi, Casey D. Johnson, A. Wree +3 more
20130 citations
Semantic Scholar
292 PAN-CASPASE INHIBITION PROTECTS AGAINST FIBROTIC NASH INDUCED BY CHOLINE DEFICIENT AMINO ACID DEFINED DIET (CDAA)
W. Lu, Akiko Eguchi, D. Sirbu, P. Contreras +5 more
20130 citations Open access
Semantic Scholar
1254 LIVER OXIDATIVE STRESS-SUPPRESSION BY NOVEL NANOPARTICLES FOR TREATMENT OF FIBROSIS ASSOCIATED WITH NONALCOHOLIC STEATOHEPATITIS
Akiko Eguchi, Toru Yoshitomi, Casey D. Johnson, A. Wree +2 more
20130 citations
Semantic Scholar
Hypoxia-inducible factor 2alpha activation disrupts cholesterol metabolism homeostasis of liver and accelerates atherosclerosis in apoE-null mice
Ai-Juan Qu, Chang-Tao Jiang, Fei Li, N. Tanaka +11 more
20130 citations
Semantic Scholar
Resistance to the Fas-induced Liver Hemorrhage and Lethality in Hepatocyte-specific Bid-deficient mice
M. Lazić, M. Berk, D. Povero, Anny Mulya +2 more
20120 citations
Semantic Scholar

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Matthew D. McGeough

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