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A. Joetham · SciRah

Researcher profile · Semantic Scholar

A. Joetham

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A. Joetham — researcher profile on SciRah

h-index: 49
Works: 149
Citations: 6,100

Most-cited papers

Naturally Occurring Lung CD4+CD25+ T Cell Regulation of Airway Allergic Responses Depends on IL-10 Induction of TGF-β1
A. Joetham, K. Takada, C. Taube, N. Miyahara +5 more
2007Journal of Immunology226 citations
Semantic Scholar
The Enhancement or Prevention of Airway Hyperresponsiveness during Reinfection with Respiratory Syncytial Virus Is Critically Dependent on the Age at First Infection and IL-13 Production1
A. Dakhama, Jungwon Park, C. Taube, A. Joetham +4 more
2005Journal of Immunology153 citations Open access
Semantic Scholar
Contribution of Antigen-Primed CD8+ T Cells to the Development of Airway Hyperresponsiveness and Inflammation Is Associated with IL-131
N. Miyahara, K. Takeda, T. Kodama, A. Joetham +6 more
2004Journal of Immunology128 citations Open access
Semantic Scholar
Requirement for leukotriene B4 receptor 1 in allergen-induced airway hyperresponsiveness.
N. Miyahara, K. Takeda, S. Miyahara, S. Matsubara +6 more
2005American Journal of Respiratory and Critical Care Medicine123 citations Open access
Semantic Scholar
Mast Cells, FcεRI, and IL-13 Are Required for Development of Airway Hyperresponsiveness after Aerosolized Allergen Exposure in the Absence of Adjuvant1
C. Taube, Xu-Dong Wei, Christina H. Swasey, A. Joetham +11 more
2004Journal of Immunology120 citations Open access
Semantic Scholar
Leukotriene B4 Receptor-1 Is Essential for Allergen-Mediated Recruitment of CD8+ T Cells and Airway Hyperresponsiveness1
N. Miyahara, K. Takeda, S. Miyahara, C. Taube +7 more
2005Journal of Immunology113 citations Open access
Semantic Scholar
Syk activation in dendritic cells is essential for airway hyperresponsiveness and inflammation.
S. Matsubara, T. Koya, K. Takeda, A. Joetham +5 more
2006American Journal of Respiratory Cell and Molecular Biology92 citations Open access
Semantic Scholar
Estrogen determines sex differences in airway responsiveness after allergen exposure.
S. Matsubara, Christina H. Swasey, J. Loader, A. Dakhama +6 more
2008American Journal of Respiratory Cell and Molecular Biology90 citations Open access
Semantic Scholar
Interleukin-1 receptor antagonist attenuates airway hyperresponsiveness following exposure to ozone.
Jungwon Park, C. Taube, Christina H. Swasey, T. Kodama +9 more
2004American Journal of Respiratory Cell and Molecular Biology84 citations Open access
Semantic Scholar
Peanut-Induced Intestinal Allergy is Mediated Through a Mast Cell-IgE-FcεRI-IL-13 Pathway
Mei-Qin Wang, K. Takeda, Y. Shiraishi, M. Okamoto +3 more
2010Journal of Allergy and Clinical Immunology78 citations Open access
Semantic Scholar
IFN-γ Production during Initial Infection Determines the Outcome of Reinfection with Respiratory Syncytial Virus
Young-Mok Lee, N. Miyahara, K. Takeda, John Prpich +5 more
200871 citations Open access
Semantic Scholar
Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation.
C. Taube, J. Thurman, K. Takeda, A. Joetham +6 more
2006Proceedings of the National Academy of Sciences of the United States of America71 citations
Semantic Scholar
Essential role of Notch signaling in effector memory CD8+ T cell–mediated airway hyperresponsiveness and inflammation
M. Okamoto, K. Takeda, A. Joetham, H. Ohnishi +6 more
2008Journal of Experimental Medicine69 citations Open access
Semantic Scholar
JAK1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses
S. Ashino, K. Takeda, Hui Li, V. Taylor +3 more
2013Journal of Allergy and Clinical Immunology66 citations Open access
Semantic Scholar
Responsiveness by Inducing IL-4 Production T Cells Initiate Lung Allergic +Jagged1 on Dendritic Cells and Notch on CD4
K. Takeda, E. Gelfand, J. Lucas, J. Domenico +4 more
200966 citations
Semantic Scholar
1,25D3 Prevents CD8+Tc2 Skewing and Asthma Development Through VDR Binding Changes to the Cyp11a1 Promoter
M. Schedel, Yi Jia, S. Michel, K. Takeda +11 more
2016Nature Communications59 citations Open access
Semantic Scholar
Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection.
A. Dakhama, Jungwon Park, C. Taube, M. El Gazzar +9 more
2005American Journal of Physiology - Lung cellular and Molecular Physiology57 citations
Semantic Scholar
Complement activation is critical to airway hyperresponsiveness after acute ozone exposure.
Jungwon Park, C. Taube, A. Joetham, K. Takeda +10 more
2004American Journal of Respiratory and Critical Care Medicine57 citations
Semantic Scholar
IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus.
Young-Mok Lee, N. Miyahara, K. Takeda, John Prpich +5 more
2008American Journal of Respiratory and Critical Care Medicine55 citations
Semantic Scholar
Leukotriene B4 release from mast cells in IgE-mediated airway hyperresponsiveness and inflammation.
N. Miyahara, H. Ohnishi, S. Miyahara, K. Takeda +8 more
2009American Journal of Respiratory Cell and Molecular Biology54 citations Open access
Semantic Scholar
Transient Neutrophil Infiltration After Allergen Challenge Is Dependent on Specific Antibodies and FcγIII Receptors1
C. Taube, A. Dakhama, Y. Rha, K. Takeda +7 more
2003Journal of Immunology54 citations Open access
Semantic Scholar
Inhibition of complement activation decreases airway inflammation and hyperresponsiveness.
C. Taube, Y. Rha, K. Takeda, Jungwon Park +6 more
2003American Journal of Respiratory and Critical Care Medicine52 citations
Semantic Scholar
Physiologic assessment of allergic rhinitis in mice: Role of the high-affinity IgE receptor (FcɛRI)
S. Miyahara, N. Miyahara, K. Takeda, A. Joetham +1 more
200551 citations
Semantic Scholar
The role of virus-specific immunoglobulin E in airway hyperresponsiveness.
A. Dakhama, Jungwon Park, C. Taube, K. Chayama +10 more
2004American Journal of Respiratory and Critical Care Medicine51 citations
Semantic Scholar
Inhibition of early airway neutrophilia does not affect development of airway hyperresponsiveness.
C. Taube, J. Nick, B. Siegmund, C. Duez +8 more
2004American Journal of Respiratory Cell and Molecular Biology43 citations
Semantic Scholar
Plasticity of Regulatory T Cells: Subversion of Suppressive Function and Conversion to Enhancement of Lung Allergic Responses12
A. Joetham, S. Matsubara, M. Okamoto, K. Takeda +3 more
2008Journal of Immunology42 citations Open access
Semantic Scholar
Loss of T Regulatory Cell Suppression following Signaling through Glucocorticoid-induced Tumor Necrosis Receptor (GITR) Is Dependent on c-Jun N-terminal Kinase Activation*
A. Joetham, H. Ohnishi, M. Okamoto, K. Takeda +4 more
2012Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Dysregulation of metabolic pathways in a mouse model of allergic asthma
K. Quinn, M. Schedel, Y. Nkrumah-Elie, A. Joetham +5 more
2017Allergy. European Journal of Allergy and Clinical Immunology40 citations
Semantic Scholar
Sequential Engagement of FcεRI on Mast Cells and Basophil Histamine H4 Receptor and FcεRI in Allergic Rhinitis
Y. Shiraishi, Yi Jia, J. Domenico, A. Joetham +3 more
2012Journal of Immunology40 citations Open access
Semantic Scholar
Erratum: Naturally occurring lung CD4+CD25+ T cell regulation of airway allergic responses depends on IL-10 induction of TGF-β (Journal of Immunology (2007) 178 (1433-1442))
A. Joetham, K. Takeda, C. Taube, N. Miyahara +5 more
200737 citations
Semantic Scholar
Reversal of allergic airway hyperreactivity after long-term allergen challenge depends on gammadelta T cells.
Zhi-Hua Cui, A. Joetham, M. Aydintug, Y. Hahn +2 more
2003American Journal of Respiratory and Critical Care Medicine37 citations
Semantic Scholar
IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells.
S. Matsubara, K. Takeda, T. Kodama, A. Joetham +6 more
2007American Journal of Respiratory Cell and Molecular Biology36 citations Open access
Semantic Scholar
Activation of naturally occurring lung CD4+CD25+ regulatory T cells requires CD8 and MHC I interaction
A. Joetham, K. Takeda, N. Miyahara, S. Matsubara +4 more
2007Proceedings of the National Academy of Sciences of the United States of America33 citations Open access
Semantic Scholar
RANTES (CCL5) regulates airway responsiveness after repeated allergen challenge.
T. Koya, K. Takeda, T. Kodama, N. Miyahara +5 more
2006American Journal of Respiratory Cell and Molecular Biology33 citations Open access
Semantic Scholar
Inducible and Naturally Occurring T Regulatory Cells Enhance Lung Allergic Responses Via Divergent Transcriptional Pathways
A. Joetham, M. Schedel, B. O'Connor, S. Kim +3 more
2016Journal of Allergy and Clinical Immunology32 citations Open access
Semantic Scholar
Vaccine-Induced CD8+ T Cell-Dependent Suppression of Airway Hyperresponsiveness and Inflammation12
K. Takeda, S. Dow, N. Miyahara, T. Kodama +7 more
2009Journal of Immunology32 citations Open access
Semantic Scholar
Spectrum of T Lymphocyte Activities Regulating Allergic Lung Inflammation
E. Gelfand, A. Joetham, Mei-Qin Wang, K. Takeda +1 more
2017Immunological Reviews30 citations Open access
Semantic Scholar
Jagged1 on Dendritic Cells and Notch on CD4+ T Cells Initiate Lung Allergic Responsiveness by Inducing IL-4 Production12
M. Okamoto, H. Matsuda, A. Joetham, Joseph J. Lucas +4 more
2009Journal of Immunology28 citations
Semantic Scholar
JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders
Géza Ambrus-Aikelin, K. Takeda, A. Joetham, M. Lazic +15 more
2023Scientific Reports26 citations Open access
Semantic Scholar
Hypoxia Enhances CD8+ Tc2 Dependent Airway Hyperresponsiveness and Inflammation Through Hypoxia Inducible Factor 1α
Fang-Kun Ning, K. Takeda, M. Schedel, J. Domenico +2 more
2019Journal of Allergy and Clinical Immunology25 citations Open access
Semantic Scholar
Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness.
S. Matsubara, K. Takeda, N. Jin, M. Okamoto +9 more
2009American Journal of Respiratory Cell and Molecular Biology25 citations Open access
Semantic Scholar
Antigen Specificity Is not Required for Modulation of Lung Allergic Responses by Naturally Occurring Regulatory T Cells1
A. Joetham, K. Takeda, M. Okamoto, C. Taube +3 more
2009Journal of Immunology25 citations Open access
Semantic Scholar
Induction and Maintenance of Airway Responsiveness to Allergen Challenge Are Determined at the Age of Initial Sensitization
E. Gelfand, A. Joetham, Zhi-Hua Cui, Annette Balhorn +4 more
200424 citations
Semantic Scholar
Effects of fexofenadine on T-cell function in a murine model of allergen-induced airway inflammation and hyperresponsiveness.
E. Gelfand, Zhi-Hua Cui, K. Takeda, A. Kanehiro +1 more
2003Journal of Allergy and Clinical Immunology23 citations Open access
Semantic Scholar
Step-Wise Epigenetic and Phenotypic Alterations Poise CD8+ T Cells to Mediate Airway Hyperresponsiveness and Inflammation
Yi Jia, K. Takeda, Jun-Yan Han, A. Joetham +4 more
2013Journal of Immunology22 citations Open access
Semantic Scholar
Physiologic assessment of allergic rhinitis in mice: role of the high-affinity IgE receptor (FcepsilonRI).
S. Miyahara, N. Miyahara, K. Takeda, A. Joetham +1 more
2005Journal of Allergy and Clinical Immunology20 citations
Semantic Scholar
Forkhead Box Protein 3 (FoxP3) Demethylation is Associated with Tolerance Induction in Peanut-Induced Intestinal Allergy
Mei-Qin Wang, Ivana V. Yang, E. Davidson, A. Joetham +3 more
2016Journal of Allergy and Clinical Immunology19 citations Open access
Semantic Scholar
Low-Dose Lipopolysaccharide Affects Lung Allergic Responses by Regulating Jagged1 Expression on Antigen-Pulsed Dendritic Cells
M. Okamoto, K. Takeda, J. Lucas, A. Joetham +2 more
2011International Archives of Allergy and Immunology18 citations Open access
Semantic Scholar
CD8 Regulates T Regulatory Cell Production of IL-6 and Maintains Their Suppressive Phenotype in Allergic Lung Disease
A. Joetham, M. Okamoto, K. Takeda, M. Schedel +3 more
2010Journal of Immunology18 citations Open access
Semantic Scholar
Induction and Maintenance of Airway Responsiveness to Allergen Challenge Are Determined at the Age of Initial Sensitization1
E. Gelfand, A. Joetham, Zhi-Hua Cui, Annette Balhorn +3 more
2004Journal of Immunology18 citations Open access
Semantic Scholar

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K. Takeda×47
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K. Takeda — researcher profile on SciRah
E. Gelfand×45
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A. Dakhama×31
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A. Dakhama — researcher profile on SciRah
N. Miyahara×23
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N. Miyahara — researcher profile on SciRah

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Annette Balhorn×13

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Jungwon Park×11

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Jungwon Park — researcher profile on SciRah

S. Matsubara×11

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S. Matsubara — researcher profile on SciRah

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T. Koya — researcher profile on SciRah

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T. Kodama — researcher profile on SciRah

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Christina H. Swasey — researcher profile on SciRah