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H. Yao · SciRah

Researcher profile · Semantic Scholar

H. Yao

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H. Yao — researcher profile on SciRah

h-index: 17
Works: 47
Citations: 1,141

Most-cited papers

Leukemia hijacks a neural mechanism to invade the central nervous system
H. Yao, Trevor T. Price, G. Cantelli, Brandon Ngo +9 more
2018Nature238 citations Open access
Semantic Scholar
Targeting the Wnt/β-catenin signaling pathway in human cancers
H. Yao, E. Ashihara, T. Maekawa
2011Expert opinion on therapeutic targets197 citations
Semantic Scholar
Identification of IL-7–Producing Cells in Primary and Secondary Lymphoid Organs Using IL-7–GFP Knock-In Mice
T. Hara, Soichiro Shitara, K. Imai, Hitoshi Miyachi +4 more
2012Journal of Immunology142 citations Open access
Semantic Scholar
C/EBPβ Is Involved in the Amplification of Early Granulocyte Precursors during Candidemia-Induced “Emergency” Granulopoiesis
Sakiko Satake, H. Hirai, Y. Hayashi, N. Shime +10 more
2012Journal of Immunology84 citations
Semantic Scholar
Activity of the multitargeted kinase inhibitor, AT9283, in imatinib-resistant BCR-ABL-positive leukemic cells.
R. Tanaka, M. Squires, S. Kimura, A. Yokota +11 more
2010Blood67 citations Open access
Semantic Scholar
Galectin‐9 ameliorates acute GVH disease through the induction of T‐cell apoptosis
Kazuki Sakai, E. Kawata, E. Ashihara, Y. Nakagawa +11 more
2011European Journal of Immunology47 citations
Semantic Scholar
AV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model
H. Yao, E. Ashihara, Jw Strovel, Y. Nakagawa +13 more
2011Blood Cancer Journal45 citations Open access
Semantic Scholar
Rakicidin A effectively induces apoptosis in hypoxia adapted Bcr‐Abl positive leukemic cells
M. Takeuchi, E. Ashihara, Y. Yamazaki, S. Kimura +7 more
2011Cancer Science38 citations Open access
Semantic Scholar
Parathyroid Hormone Enhances Hematopoietic Expansion Via Upregulation of Cadherin‐11 in Bone Marrow Mesenchymal Stromal Cells
H. Yao, Y. Miura, Satoshi Yoshioka, M. Miura +11 more
2014Stem Cells34 citations Open access
Semantic Scholar
C/EBPβ promotes BCR–ABL-mediated myeloid expansion and leukemic stem cell exhaustion
Yoshihiro Hayashi, H. Hirai, Naoka Kamio, H. Yao +6 more
2012Leukemia31 citations Open access
Semantic Scholar
Growth inhibition of imatinib-resistant CML cells with the T315I mutation and hypoxia-adaptation by AV65--a novel Wnt/β-catenin signaling inhibitor.
R. Nagao, E. Ashihara, S. Kimura, J. Strovel +8 more
2011Cancer Letters26 citations Open access
Semantic Scholar
Osteoclasts are involved in the maintenance of dormant leukemic cells.
A. Yokota, S. Kimura, R. Tanaka, M. Takeuchi +8 more
2010Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis24 citations
Semantic Scholar
CCAAT/Enhancer‐Binding Protein β Expressed by Bone Marrow Mesenchymal Stromal Cells Regulates Early B‐Cell Lymphopoiesis
Satoshi Yoshioka, Y. Miura, H. Yao, Sakiko Satake +7 more
2014Stem Cells23 citations Open access
Semantic Scholar
Isolation of mesenchymal stromal/stem cells from small-volume umbilical cord blood units that do not qualify for the banking system
Satoshi Yoshioka, Y. Miura, Masaki Iwasa, A. Fujishiro +9 more
2015International journal of hematology22 citations
Semantic Scholar
The role of growth differentiation factor 15 in the pathogenesis of primary myelofibrosis
Tatsuki Uchiyama, H. Kawabata, Y. Miura, Satoshi Yoshioka +8 more
2015Cancer Medicine22 citations Open access
Semantic Scholar
Chimerism of bone marrow mesenchymal stem/stromal cells in allogeneic hematopoietic cell transplantation
Y. Miura, Satoshi Yoshioka, H. Yao, A. Takaori-Kondo +2 more
2013Chimerism22 citations Open access
Semantic Scholar
Rapid automated detection of ABL kinase domain mutations in imatinib-resistant patients.
R. Tanaka, S. Kimura, E. Ashihara, M. Yoshimura +14 more
2011Cancer Letters20 citations
Semantic Scholar
Early osteoinductive human bone marrow mesenchymal stromal/stem cells support an enhanced hematopoietic cell expansion with altered chemotaxis- and adhesion-related gene expression profiles.
N. Sugino, Y. Miura, H. Yao, Masaki Iwasa +6 more
2016Biochemical and Biophysical Research Communications - BBRC17 citations Open access
Semantic Scholar
Multiple myeloma cells adapted to long-exposure of hypoxia exhibit stem cell characters with TGF-β/Smad pathway activation.
Y. Nakagawa, E. Ashihara, H. Yao, A. Yokota +5 more
2018Biochemical and Biophysical Research Communications - BBRC12 citations
Semantic Scholar
Mitochondrial Protein Synthesis Is Essential for Terminal Differentiation of CD45– TER119–Erythroid and Lymphoid Progenitors
K. Gotoh, Yuya Kunisaki, Soichi Mizuguchi, D. Setoyama +10 more
2020iScience9 citations Open access
Semantic Scholar
Pan-PI3Ki targets multiple B-ALL microenvironment interactions that fuel systemic and CNS relapse
Sarah M. Ridge, Andrew E Whiteley, H. Yao, Trevor T. Price +5 more
2021Leukemia and Lymphoma4 citations Open access
Semantic Scholar
PI3Kδ Inhibition Suppresses Central Nervous System Involvement of Acute Lymphoblastic Leukemia
H. Yao, Trevor T. Price, Lindsey A. Olivere, M. Warner +2 more
20164 citations
Semantic Scholar
[Supportive therapies for myeloid leukemia including blood transfusion and growth factors].
H. Yao, E. Ashihara, T. Maekawa
2009Nihon rinsho. Japanese journal of clinical medicine3 citations
Semantic Scholar
A Novel β-catenin Inhibitor, AV65 Suppresses the Growth of CML Cell Lines Which Acquire Imatinib-Resistance Because of Abl Kinase Domain Mutations Including T315I and Hypoxia-Adaptation.
R. Nagao, S. Kimura, E. Ashihara, M. Takeuchi +6 more
20083 citations
Semantic Scholar
Inhibition of Wnt/β-Catenin Signaling by AV65 Treatment Caused Cell Cycle Arrest and Induced Caspase-Independent or -Dependent Apoptosis in CML Cells.
R. Nagao, E. Ashihara, S. Kimura, H. Yao +8 more
20092 citations
Semantic Scholar
Roles of Osteoclasts in Leukemic Cells
A. Yokota, S. Kimura, R. Tanaka, R. Nagao +7 more
20082 citations
Semantic Scholar
PI3Kα/δ Inhibitor, Copanlisib, Inhibits Acute Lymphoblastic Leukemia Cell Growth, Increases Survival and Inhibits CNS Disease Progression in Leukemic Mice
Sarah M. Ridge, H. Yao, Trevor T. Price, Andrew E Whiteley +2 more
2019Blood1 citations Open access
Semantic Scholar
Essential Roles of C/EBPβ in Survival of Ly6C– monocytes
Akihiro Tamura, H. Hirai, A. Yokota, Atsushi Sato +5 more
20141 citations
Semantic Scholar
BCR/ABL-Mediated Myeloid Expansion Is Promoted by C/EBPβ, a Regulator of Emergency Granulopoiesis,
Y. Hayashi, H. Hirai, H. Yao, Satoshi Yoshioka +7 more
20111 citations
Semantic Scholar
AV-65, a Novel Inhibitor of the Wnt/β-Catenin Signaling Pathway, Inhibits the Proliferation of Myeloma Cells.
H. Yao, E. Ashihara, R. Nagao, S. Kimura +5 more
20091 citations
Semantic Scholar
Expressed by Bone Marrow Mesenchymal Stromal Cells Regulates Early B-Cell Lymphopoiesis( Dissertation
Satoshi Yoshioka, Yasuo Miura, H. Yao, Sakiko Satake +7 more
20230 citations
Semantic Scholar
[Central nervous system involvement in acute lymphoblastic leukemia].
H. Yao
2019[Rinsho ketsueki] The Japanese journal of clinical hematology0 citations
Semantic Scholar
Acute Lymphoblastic Leukemia Cells Bypass the Blood Brain Barrier to Enter the CNS Via a Neuronal Developmental Pathway
H. Yao, M. Warner, Trevor T. Price, Lindsey A. Olivere +7 more
20170 citations
Semantic Scholar
C/EBPβ Promotes Initial Expansion and Exhaustion of Hematopoietic Stem and Progenitor Cells in Response to Hematopoietic Stresses
Atsushi Sato, H. Hirai, Akihiro Tamura, A. Yokota +7 more
20140 citations
Semantic Scholar
C/EBPβ expressed By Bone Marrow Mesenchymal Stromal Cells Is Indispensable For Precursor B-Cell Lymphopoiesis
Y. Miura, H. Yao, Masaki Iwasa, Atsushi Sato +6 more
20130 citations
Semantic Scholar
Cytokine-STATs Signalings Upregulate C/EBPβ In BCR-ABL+ Leukemic Cells Independently From BCR-ABL/JAK-STAT Pathway
A. Yokota, H. Hirai, Y. Hayashi, Akihiro Tamura +7 more
20130 citations
Semantic Scholar
Direct Interaction With Bone Marrow Mesenchymal Stromal/Stem Cells Is Required For Hematopoietic Expansion By Parathyroid Hormone
H. Yao, Y. Miura, Satoshi Yoshioka, Masaki Iwasa +7 more
20130 citations
Semantic Scholar
Hypoxia-Adapted Myeloma Cells Possess Stem Cell Character
Y. Nakagawa, H. Yao, A. Yokota, Y. Miura +4 more
20130 citations
Semantic Scholar
Granulopoiesis Candidemia-Induced ' ' Emergency ' ' Early Granulocyte Precursors during Is Involved in the Amplification of β C / EBP
Granulopoiesis Sakiko Satake, H. Hirai, Y. Hayashi, N. Shime +10 more
20120 citations
Semantic Scholar
Mesenchymal Stem Cells Skewed Their Phenotype Toward the Osteogenic Lineage Support the Hematopoietic Cell Differentiation
H. Yao, Y. Miura, Satoshi Yoshioka, Y. Hayashi +3 more
20120 citations
Semantic Scholar
Expression of C/EBPβ in Bone Marrow Mesenchymal Stem Cells Is Mandatory for Early-Stage B Cell Lymphopoiesis
Satoshi Yoshioka, Y. Miura, H. Yao, Y. Hayashi +5 more
20120 citations
Semantic Scholar
C/EBPβ Is Upregulated Through STAT5 and Accelerates Exhaustion of Leukemic Stem Cells During BCR-ABL-Mediated Myeloid Expansion
Y. Hayashi, H. Hirai, H. Yao, Satoshi Yoshioka +6 more
20120 citations
Semantic Scholar
C/EBPβ-Mediated Expansion of Hematopoietic Stem/Progenitors Precedes ‘Emergency’ Granulopoiesis Induced by Candidemia.
Akihiro Tamura, H. Hirai, Y. Hayashi, H. Yao +4 more
20120 citations
Semantic Scholar
Parathyroid Hormone Stimulates Human Mesenchymal Stem Cells to Enhance the Expansion of Hematopoietic Stem Cells
H. Yao, Y. Miura, Satoshi Yoshioka, Y. Hayashi +2 more
20110 citations
Semantic Scholar
Candidemia-Induced Emergency Granulopoiesis Consists of Successive Dual Waves Triggered by the Shift From C/EBPalpha to C/EBPbeta Dependency.
Sakiko Satake, H. Hirai, N. Shime, R. Nagao +8 more
20100 citations
Semantic Scholar
Automated and Rapid Detection of BCR-ABL Kinase Domain Mutations in IM Resistant Patients with Ph+ Leukemias.
R. Tanaka, S. Kimura, Toshiya Hosomi, M. Hirai +10 more
20090 citations
Semantic Scholar
Osteoclasts Are Involved in the Maintenance of Dormant Leukemic Cells.
A. Yokota, S. Kimura, R. Tanaka, M. Takeuchi +5 more
20090 citations
Semantic Scholar

Frequent co-authors

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T. Maekawa×38
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T. Maekawa — researcher profile on SciRah
H. Hirai×30
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H. Hirai — researcher profile on SciRah
E. Ashihara×27
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E. Ashihara — researcher profile on SciRah
Y. Miura×22
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Y. Miura — researcher profile on SciRah

×17

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Y. Hayashi — researcher profile on SciRah

Satoshi Yoshioka×16

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Satoshi Yoshioka — researcher profile on SciRah

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A. Yokota — researcher profile on SciRah

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R. Nagao — researcher profile on SciRah

Akihiro Tamura×13

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Akihiro Tamura — researcher profile on SciRah

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R. Tanaka — researcher profile on SciRah

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S. Kimura — researcher profile on SciRah

M. Takeuchi×10

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M. Takeuchi — researcher profile on SciRah