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G. Rigdon · SciRah

Researcher profile · Semantic Scholar

G. Rigdon

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G. Rigdon — researcher profile on SciRah

h-index: 22
Works: 45
Citations: 1,744

Most-cited papers

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia.
K. Ataga, W. Smith, L. D. de Castro, P. Swerdlow +7 more
2008Blood214 citations Open access
Semantic Scholar
Effect of linking bridge modifications on the antipsychotic profile of some phthalimide and isoindolinone derivatives.
Mark H. Norman, D. Minick, G. Rigdon
1996Journal of Medicinal Chemistry169 citations Open access
Semantic Scholar
A novel, potent and selective nonpeptidic delta opioid receptor agonist BW373U86.
Kwen-jen Chang, G. Rigdon, J. L. Howard, R. Mcnutt
1993Journal of Pharmacology and Experimental Therapeutics162 citations
Semantic Scholar
5-Hydroxytryptamine 1a receptor agonists block prepulse inhibition of acoustic startle reflex.
G. Rigdon, J. K. Weatherspoon
1992Journal of Pharmacology and Experimental Therapeutics131 citations
Semantic Scholar
N-(6-Chloro-pyridin-3-yl)-3,4-difluoro-benzamide (ICA-27243): A Novel, Selective KCNQ2/Q3 Potassium Channel Activator
A. Wickenden, J. Krajewski, B. London, P. Wagoner +5 more
2008Molecular Pharmacology115 citations
Semantic Scholar
Nucleus basalis involvement in conditioned neuronal responses in the rat frontal cortex
G. Rigdon, James H. Pirch
1986Journal of Neuroscience93 citations Open access
Semantic Scholar
Prepulse inhibition as a screening test for potential antipsychotics
G. Rigdon, K. Viik
199173 citations
Semantic Scholar
In Vivo Profile of ICA-27243 [N-(6-Chloro-pyridin-3-yl)-3,4-difluoro-benzamide], a Potent and Selective KCNQ2/Q3 (Kv7.2/Kv7.3) Activator in Rodent Anticonvulsant Models
R. Roeloffs, A. Wickenden, C. Crean, S. Werness +5 more
2008Journal of Pharmacology and Experimental Therapeutics62 citations
Semantic Scholar
Novel inhibitors of the Gardos channel for the treatment of sickle cell disease.
G. Mcnaughton-Smith, J. F. Burns, J. Stocker, G. Rigdon +4 more
2008Journal of Medicinal Chemistry58 citations Open access
Semantic Scholar
Cyclic benzamides as mixed dopamine D2/serotonin 5-HT2 receptor antagonists: potential atypical antipsychotic agents.
Mark H. Norman, G. Rigdon, F. Navas, B. R. Cooper
1994Journal of Medicinal Chemistry57 citations Open access
Semantic Scholar
Indanylidenes. 1. Design and synthesis of (E)-2-(4,6-difluoro-1-indanylidene)acetamide, a potent, centrally acting muscle relaxant with antiinflammatory and analgesic activity.
D. Musso, F. Cochran, J. L. Kelley, Ed W. McLean +8 more
2003Journal of Medicinal Chemistry56 citations Open access
Semantic Scholar
N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy.
George Amato, R. Roeloffs, G. Rigdon, Brett M. Antonio +5 more
2011ACS Medicinal Chemistry Letters50 citations Open access
Semantic Scholar
Microinjection of procaine or GABA into the nucleus basalis magnocellularis affects cue-elicited unit responses in the rat frontal cortex.
G. Rigdon, J. Pirch
1984Experimental Neurology50 citations
Semantic Scholar
Generation of cortical event-related slow potentials in the rat involves nucleus basalis cholinergic innervation.
James H. Pirch, Mary Jo Corbus, G. Rigdon, W. Lyness
1986Electroencephalography and Clinical Neurophysiology46 citations
Semantic Scholar
Differential effects of apomorphine on prepulse inhibition of acoustic startle reflex in two rat strains
G. Rigdon
2005Psychopharmacology41 citations
Semantic Scholar
KCNQ potassium channels: drug targets for the treatment of epilepsy and pain
A. Wickenden, R. Roeloffs, G. Mcnaughton-Smith, G. Rigdon
200439 citations
Semantic Scholar
Serotonin uptake blockers inhibit the firing of presumed serotonergic dorsal raphe neurons in vitro
G. Rigdon, Ching M. Wang
199139 citations
Semantic Scholar
Pharmacological Properties of 403U76, a New Chemical Class of 5‐Hydroxytryptamine‐ and Noradrenaline‐reuptake Inhibitor
R. Ferris, L. Brieaddy, N. Mehta, E. Hollingsworth +5 more
1995The Journal of pharmacy and pharmacology35 citations
Semantic Scholar
Urethane affects the rat visual system at subanesthetic doses.
R. Dyer, G. Rigdon
1987Physiology and Behavior31 citations
Semantic Scholar
Kv7 potassium channel activation with ICA-105665 reduces photoparoxysmal EEG responses in patients with epilepsy
D. K. Kasteleijn-Nolst Trenite, V. Biton, J. French, B. Abou-Khalil +5 more
2013Epilepsia25 citations Open access
Semantic Scholar
Basal forebrain modulation of cortical cell activity during conditioning.
James H. Pirch, G. Rigdon, H. Rucker, Kathy Turco
1991Advances in Experimental Medicine and Biology24 citations
Semantic Scholar
Single-unit and slow potential responses from rat frontal cortex during associative conditioning.
J. Pirch, M. J. Corbus, G. Rigdon
1983Experimental Neurology24 citations
Semantic Scholar
Ketamine alters rat flash evoked potentials.
G. Rigdon, Robert S. Dyers
1988Pharmacology, Biochemistry and Behavior20 citations
Semantic Scholar
Conditioning-related single unit activity in the frontal cortex of urethane anesthetized rats.
J. Pirch, M. J. Corbus, G. Rigdon
1985International Journal of Neuroscience20 citations
Semantic Scholar
Is clozapine selective for the dopamine D4 receptor?
M. Durcan, G. Rigdon, Mark H. Norman, Philip F. Morgan
1995Life Science19 citations
Semantic Scholar
1192U90 in Animal Tests That Predict Antipsychotic Efficacy, Anxiolysis, and Extrapyramidal Side Effects
G. Rigdon, M. Norman, B. Cooper, J. L. Howard +4 more
1996Neuropsychopharmacology15 citations
Semantic Scholar
Effect of perinatal monosodium glutamate administration on visual evoked potentials of juvenile and adult rats.
G. Rigdon, William K. Boyes, R. Dyer
1989Neurotoxicology and Teratology15 citations
Semantic Scholar
Phase I study of PF‐04895162, a Kv7 channel opener, reveals unexpected hepatotoxicity in healthy subjects, but not rats or monkeys: clinical evidence of disrupted bile acid homeostasis
M. Aleo, J. Aubrecht, P. Bonin, Deborah A. Burt +7 more
2019Pharmacology Research & Perspectives13 citations Open access
Semantic Scholar
Indanylidenes. 2. Design and synthesis of (E)-2-(4-chloro-6-fluoro-1-indanylidene)-N-methylacetamide, a potent antiinflammatory and analgesic agent without centrally acting muscle relaxant activity.
D. Musso, G. F. Orr, F. Cochran, J. L. Kelley +4 more
2003Journal of Medicinal Chemistry13 citations
Semantic Scholar
Overview of the CNS pharmacology of BW 1370U87: A chemically novel, reversible, selective MAO‐A inhibitor with potential to be a new antidepressant drug
B. Cooper, H. White, O. Beek, Ronald M. Norton +4 more
19929 citations
Semantic Scholar
Anti-haemolytic Effect of Senicapoc and Decrease in NT-proBNP in Adults with Sickle Cell Anaemia
Caterina P. Minniti, Jonathan M. Wilson, Laurel G Mendelsohn, G. Rigdon +3 more
2011British Journal of Haematology6 citations Open access
Semantic Scholar
A phase i safety, pharmacokinetic, and pharmacodynamic study of ascending single, oral doses of ICA-17043, a novel gardos channel inhibitor for the treatment of sickle cell disease
G. Rigdon, J. Stocker, G. Mcnaughton-Smith, Heyward Hull +1 more
20006 citations
Semantic Scholar
Ontogeny of flash‐evoked potentials in unanesthetized rats
G. Rigdon, R. Dyer
1987International Journal of Developmental Neuroscience5 citations
Semantic Scholar
Potentiation of the behavioral effects of 5‐hydroxytryptophan by BW 1370U87, a selective monoamine oxidase‐A inhibitor
Christopher J. Burchall, Francis E. Soroko, G. Rigdon
19924 citations
Semantic Scholar
Dissimilar responses of cortical neurons to chronic trazodone or desipramine treatment.
S. Peterson, T. Napier, G. Rigdon, J. Pirch
1983Progress in Neuro-psychopharmacology and Biological Psychiatry3 citations
Semantic Scholar
Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia. Commentary
C. Joiner, K. Ataga, W. Smith, L. D. de Castro +8 more
20081 citations
Semantic Scholar
2- (Imidazol- 1-yl)- 1-(2-naphthyl)ethanone Oxime
G. Rigdon, G. Ferris, S. Braz
19981 citations
Semantic Scholar
Biochemical and pharmacological properties of BW 1370U87 — a novel, selective monoamine oxidase A inhibitor
Helen L. White, O. Beek, G. Rigdon, G. Kraemer +1 more
19911 citations
Semantic Scholar
EFFICACY AND SAFETY OF THE GARDOS CHANNEL BLOCKER, SENICAPOC (ICA- 17043), IN PATIENTS WITH SICKLE CELL ANEMIA Running Title: Phase II senicapoc study in sickle cell anemia
E. Vichinsky, A. Kutlar, E. Orringer, G. Rigdon +7 more
20080 citations
Semantic Scholar
Variations in the Use of Transcranial Doppler and Chronic Transfusion Therapy for Stroke Prevention in Pediatric Populations at Sickle Cell Centers.
A. Mulberg, M. Behm, Catherine Magia, R. Adams +2 more
20060 citations
Semantic Scholar
Antagonistes du canal de gardos
G. Mcnaughton-Smith, G. Rigdon, J. Stocker
20000 citations
Semantic Scholar
Biochemical and pharmacologic properties of 2614W94, a reversible, competitive inhibitor of monoamine oxidase‐A
H. White, Philip W. Scates, J. Harrelson, T. E. Johnson +6 more
19980 citations
Semantic Scholar
Bicyclic amide derivatives and use as muscle relaxants thereof.
J. L. Kelley, G. Rigdon, B. Cooper, Ed W. McLean +2 more
19940 citations
Semantic Scholar
Novel flash evoked potential fep change produced by diazepam in rats
R. Dyer, G. Rigdon, L. Mayo
19870 citations
Semantic Scholar
Role of the nucleus basalis in conditioned responses of cortical neurons in the rat
G. Rigdon
19850 citations
Semantic Scholar

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G. Mcnaughton-Smith×6
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