L. Maquat

Most-cited papers

lncRNAs transactivate Staufen1-mediated mRNA decay by duplexing with 3'UTRs via Alu elements
Chenguang Gong, L. Maquat
2011Nature1,197 citations Open access
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Quality and quantity control of gene expression by nonsense-mediated mRNA decay
Tatsuaki Kurosaki, M. W. Popp, L. Maquat
2019Nature reviews. Molecular cell biology721 citations Open access
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Regulation of cytoplasmic mRNA decay
Daniel R Schoenberg, L. Maquat
2012Nature reviews genetics698 citations Open access
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Quality control of eukaryotic mRNA: safeguarding cells from abnormal mRNA function.
O. Isken, L. Maquat
2007Genes & Development633 citations Open access
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Retrotransposons as regulators of gene expression
R. Elbarbary, Bronwyn A. Lucas, L. Maquat
2016Science390 citations Open access
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Organizing Principles of Mammalian Nonsense-Mediated mRNA Decay
M. W. Popp, L. Maquat
2013Annual Review of Genetics389 citations Open access
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Nonsense-mediated mRNA decay in humans at a glance
Tatsuaki Kurosaki, L. Maquat
2016Journal of Cell Science382 citations Open access
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The multiple lives of NMD factors: balancing roles in gene and genome regulation
O. Isken, L. Maquat
2008Nature reviews genetics338 citations Open access
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Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay.
O. Isken, Y. Kim, Nao Hosoda, Greg L. Mayeur +2 more
2008Cell298 citations Open access
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Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome Engineering and Personalized Medicine
M. W. Popp, L. Maquat
2016Cell288 citations Open access
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Applying nonsense-mediated mRNA decay research to the clinic: progress and challenges.
H. Kuzmiak, L. Maquat
2006Trends in Molecular Medicine252 citations
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The Pioneer Round of Translation: Features and Functions
L. Maquat, W. Tarn, O. Isken
2010Cell233 citations Open access
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Regulation of Multiple Core Spliceosomal Proteins by Alternative Splicing-Coupled Nonsense-Mediated mRNA Decay
Arneet L. Saltzman, Y. Kim, Q. Pan, Matthew M Fagnani +2 more
2008Molecular and Cellular Biology225 citations Open access
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A Yeast Model of FUS/TLS-Dependent Cytotoxicity
S. Ju, D. Tardiff, Haesun Han, Kanneganti Divya +8 more
2011PLoS Biology213 citations Open access
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UPFront and center in RNA decay: UPF1 in nonsense-mediated mRNA decay and beyond
Y. Kim, L. Maquat
2019RNA: A publication of the RNA Society212 citations Open access
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SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs.
Chenguang Gong, Y. Kim, Collynn F. Woeller, Ya-Lan Tang +1 more
2009Genes & Development193 citations Open access
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A post-translational regulatory switch on UPF1 controls targeted mRNA degradation
Tatsuaki Kurosaki, Wencheng Li, M. Hoque, M. W. Popp +3 more
2014Genes & Development168 citations Open access
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Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question
Jungwook Hwang, L. Maquat
2011Current Opinion in Genetics and Development146 citations Open access
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Nonsense-mediated mRNA Decay and Cancer
M. W. Popp, L. Maquat
2017Current Opinion in Genetics and Development144 citations Open access
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Rules that govern UPF1 binding to mRNA 3′ UTRs
Tatsuaki Kurosaki, L. Maquat
2013Proceedings of the National Academy of Sciences of the United States of America133 citations Open access
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UPF1 Association With the Cap-binding Protein, CBP80, Promotes Nonsense-mediated mRNA Decay at Two Distinct Steps
Jungwook Hwang, Hanae Sato, Ya-Lan Tang, Daiki Matsuda +1 more
2010Molecules and Cells133 citations Open access
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Cellular RNA Surveillance in Health and Disease
S. Wolin, L. Maquat
2019Science127 citations Open access
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STAU1 binding 3' UTR IRAlus complements nuclear retention to protect cells from PKR-mediated translational shutdown.
R. Elbarbary, Wencheng Li, Bin Tian, L. Maquat
2013Genes & Development127 citations Open access
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Temporal and spatial characterization of nonsense-mediated mRNA decay.
Tatjana Trcek, Hanae Sato, R. Singer, L. Maquat
2013Genes & Development122 citations Open access
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Control of myogenesis by rodent SINE-containing lncRNAs.
Jiashi Wang, Chenguang Gong, L. Maquat
2013Genes & Development107 citations Open access
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Remodeling of the pioneer translation initiation complex involves translation and the karyopherin importin beta.
Hanae Sato, L. Maquat
2009Genes & Development105 citations Open access
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Re-capping the message
Daniel R Schoenberg, L. Maquat
2009TIBS -Trends in Biochemical Sciences. Regular ed99 citations Open access
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Tudor-SN-mediated endonucleolytic decay of human-cell microRNAs promotes G1/S phase transition
R. Elbarbary, Keita Miyoshi, Jason R. Myers, Peicheng Du +3 more
2017Science90 citations Open access
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Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity
Eonyoung Park, M. Gleghorn, L. Maquat
2012Proceedings of the National Academy of Sciences of the United States of America84 citations Open access
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Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics
M. W. Popp, L. Maquat
2015Nature Communications82 citations Open access
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The nuclear cap-binding complex as choreographer of gene transcription and pre-mRNA processing
Xavier Rambout, L. Maquat
2020Genes & Development74 citations Open access
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Efficiency of the pioneer round of translation affects the cellular site of nonsense-mediated mRNA decay.
Hanae Sato, Nao Hosoda, L. Maquat
2008Molecules and Cells74 citations Open access
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Staufen1 dimerizes via a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay
M. Gleghorn, Chenguang Gong, C. Kielkopf, L. Maquat
2013Nature Structural &Molecular Biology71 citations Open access
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The Dharma of Nonsense-Mediated mRNA Decay in Mammalian Cells
M. W. Popp, L. Maquat
2014Molecules and Cells70 citations Open access
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Beyond Transcription: Roles of Transcription Factors in Pre-mRNA Splicing
Xavier Rambout, F. Dequiedt, L. Maquat
2017Chemical Reviews69 citations Open access
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mRNA–mRNA duplexes that auto-elicit Staufen1-mediated mRNA decay
Chenguang Gong, Ya-Lan Tang, L. Maquat
2013Nature Structural &Molecular Biology64 citations Open access
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“Black sheep” that don’t leave the dsRBD fold
M. Gleghorn, L. Maquat
2014TIBS -Trends in Biochemical Sciences. Regular ed59 citations Open access
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Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA
Daiki Matsuda, Nao Hosoda, Y. Kim, L. Maquat
2007Nature Structural &Molecular Biology58 citations
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CBP80-Promoted mRNP Rearrangements during the Pioneer Round of Translation, Nonsense-Mediated mRNA Decay, and Thereafter
L. Maquat, Jungwook Hwang, H. Sato, Ya-Lan Tang
2011Cold Spring Harbor Symposia on Quantitative Biology55 citations Open access
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Evidence for convergent evolution of SINE-directed Staufen-mediated mRNA decay
Bronwyn A. Lucas, E. Lavi, L. Shiue, Hana Cho +6 more
2018Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
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Gene expression networks: competing mRNA decay pathways in mammalian cells
L. Maquat, Chenguang Gong
2009Biochemical Society Transactions46 citations Open access
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Loss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decay
Tatsuaki Kurosaki, Naoto Imamachi, C. Pröschel, Shuhei Mitsutomi +3 more
2021Nature Cell Biology41 citations Open access
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Biochemical Analysis of Long Non-coding RNA-containing Ribonucleoprotein Complexes
Chenguang Gong, M. W. Popp, L. Maquat
2012Methods41 citations Open access
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NMD-degradome sequencing reveals ribosome-bound intermediates with 3′-end non-templated nucleotides
Tatsuaki Kurosaki, Keita Miyoshi, Jason R. Myers, L. Maquat
2018Nature Structural & Molecular Biology37 citations Open access
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Viral subversion of nonsense-mediated mRNA decay
M. W. Popp, Hana Cho, L. Maquat
2020RNA: A publication of the RNA Society36 citations Open access
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UPF1 helicase promotes TSN-mediated miRNA decay
R. Elbarbary, Keita Miyoshi, O. Hedaya, Jason R. Myers +1 more
2017Genes & Development35 citations Open access
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AKT Constitutes a Signal-Promoted Alternative Exon-Junction Complex that Regulates Nonsense-Mediated mRNA Decay
Hana Cho, E. Abshire, M. W. Popp, C. Pröschel +3 more
2022Molecules and Cells33 citations Open access
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“Alu”strious long ncRNAs and their roles in shortening mRNA half-lives
Chenguang Gong, L. Maquat
2011Cell Cycle28 citations Open access
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Short interspersed nuclear element (SINE)-mediated post-transcriptional effects on human and mouse gene expression: SINE-UP for active duty
L. Maquat
2020Philosophical Transactions of the Royal Society of London. Biological Sciences25 citations Open access
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Transcriptional coactivator PGC-1α contains a novel CBP80-binding motif that orchestrates efficient target gene expression
Hana Cho, Xavier Rambout, M. Gleghorn, P. Nguyen +6 more
2018Genes & Development23 citations Open access
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