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L. Kattenhorn · SciRah

Researcher profile · Semantic Scholar

L. Kattenhorn

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L. Kattenhorn — researcher profile on SciRah

h-index: 16
Works: 24
Citations: 1,876

Most-cited papers

AAV-expressed eCD4-Ig provides durable protection from multiple SHIV challenges
M. Gardner, L. Kattenhorn, Hema R Kondur, M. von Schaewen +30 more
2015Nature316 citations Open access
Semantic Scholar
A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae.
L. Kattenhorn, G. Korbel, B. Kessler, E. Spooner +1 more
2005Molecules and Cells261 citations Open access
Semantic Scholar
Combination of the STING Agonist MIW815 (ADU-S100) and PD-1 Inhibitor Spartalizumab in Advanced/Metastatic Solid Tumors or Lymphomas: An Open-Label, Multicenter, Phase Ib Study
F. Meric-Bernstam, R. Sweis, S. Kasper, O. Hamid +17 more
2022Clinical Cancer Research181 citations Open access
Semantic Scholar
Identification of Proteins Associated with Murine Cytomegalovirus Virions
L. Kattenhorn, R. Mills, Markus Wagner, A. Lomsadze +4 more
2004Journal of Virology171 citations Open access
Semantic Scholar
A Deubiquitinating Activity Is Conserved in the Large Tegument Protein of the Herpesviridae
Christian Schlieker, G. Korbel, L. Kattenhorn, H. Ploegh
2005Journal of Virology161 citations Open access
Semantic Scholar
Adeno-Associated Virus Gene Therapy for Liver Disease
L. Kattenhorn, Christopher H. Tipper, Lorelei Stoica, Deborah S. Geraghty +3 more
2016Human Gene Therapy133 citations Open access
Semantic Scholar
Structure of a Herpesvirus-Encoded Cysteine Protease Reveals a Unique Class of Deubiquitinating Enzymes
Christian Schlieker, W. Weihofen, E. Frijns, L. Kattenhorn +2 more
2007Molecules and Cells131 citations Open access
Semantic Scholar
High-Molecular-Weight Protein (pUL48) of Human Cytomegalovirus Is a Competent Deubiquitinating Protease: Mutant Viruses Altered in Its Active-Site Cysteine or Histidine Are Viable
Jian-Lei Wang, Amy N Loveland, L. Kattenhorn, H. Ploegh +1 more
2006Journal of Virology113 citations
Semantic Scholar
Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission
K. Bialas, Takayuki Tanaka, Dollnovan Tran, V. Varner +18 more
2015Proceedings of the National Academy of Sciences of the United States of America106 citations Open access
Semantic Scholar
A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation
K. Jarosinski, L. Kattenhorn, B. Kaufer, H. Ploegh +1 more
2007Proceedings of the National Academy of Sciences of the United States of America87 citations Open access
Semantic Scholar
Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies
M. Gardner, I. Fetzer, L. Kattenhorn, Meredith E. Davis-Gardner +10 more
2019Molecular Therapy55 citations Open access
Semantic Scholar
AAV-delivered eCD4-Ig protects rhesus macaques from high-dose SIVmac239 challenges
M. Gardner, C. Fellinger, L. Kattenhorn, Meredith E. Davis-Gardner +12 more
2019Science Translational Medicine50 citations Open access
Semantic Scholar
A Gammaherpesvirus Ubiquitin-Specific Protease Is Involved in the Establishment of Murine Gammaherpesvirus 68 Infection
S. Gredmark-Russ, M. Isaacson, L. Kattenhorn, Evelyn J. Cheung +2 more
2009Journal of Virology34 citations Open access
Semantic Scholar
The US3 Kinase of Herpes Simplex Virus Phosphorylates the RNA Sensor RIG-I To Suppress Innate Immunity
M. van Gent, Jessica J. Chiang, Santoshi Muppala, C. Chiang +5 more
2021Journal of Virology30 citations Open access
Semantic Scholar
Scientific and Regulatory Policy Committee Points to Consider: Nonclinical Research and Development of In Vivo Gene Therapy Products, Emphasizing Adeno-Associated Virus Vectors
J. Hutt, B. Assaf, B. Bolon, J. Cavagnaro +5 more
2021Toxicologic pathology (Print)18 citations
Semantic Scholar
Impact of intravenous infusion time on AAV8 vector pharmacokinetics, safety, and liver transduction in cynomolgus macaques
Jenny A. Greig, J. Nordin, Erin Bote, L. Makaron +5 more
2016Molecular Therapy: Methods & Clinical Development18 citations Open access
Semantic Scholar
Meeting Report
V. Sasseville, K. Mansfield, J. Mankowski, C. Tremblay +25 more
2012Catalysis surveys from Asia11 citations Open access
Semantic Scholar
Determining the Minimally Effective Dose of a Clinical Candidate Adeno-Associated Virus Vector in a Mouse Model of Hemophilia A
Jenny A. Greig, Melanie K. Smith, J. Nordin, Tamara Goode +6 more
2021Human Gene Therapy2 citations Open access
Semantic Scholar
Strategies for Selection of AAV Vectors for Administration to Liver: Studies in Nonhuman Primates
Lili Wang, James M. Wilson, R. Calcedo, Peter Bell +7 more
20161 citations
Semantic Scholar
2019-03-06 Anti-drug Antibody Responses Impair Prophylaxis Mediated by AAV-Delivered HIV-1 Broadly Neutralizing Antibodies
M. Gardner, I. Fetzer, L. Kattenhorn, Meredith E. Davis-Gardner +11 more
20190 citations
Semantic Scholar
227. A Dose-Escalating Preclinical Study to Determine the Efficacy, MED, and Safety of a Clinical Candidate Vector in a Mouse Model of Hemophilia B
Lili Wang, John White, Zhenning He, Tamara Goode +9 more
20160 citations Open access
Semantic Scholar
Cytomegalovirus-Neutralizing Antibody Responses are Associated With Protection Against Fetal Loss, but Not Placental Transmission, in a Novel Rhesus Monkey Model of Congenital CMV Transmission
K. Bialas, Takayuki Tanaka, Dollnovan Tran, Eduardo Cisneros de la Rosa +8 more
20150 citations Open access
Semantic Scholar
Primates and in Nonhuman Primate Species Used in Drug Safety Studies Meeting Report : Spontaneous Lesions and Diseases in Wild , Captive-Bred , and Zoo-Housed Nonhuman
G. Sasseville, K. Mansfield, J. Mankowski, C. Tremblay +25 more
20120 citations
Semantic Scholar
Crystal structure of the ubiquitin-specific protease encoded by murine cytomegalovirus tegument protein M48 in complex with a ubquitin-based suicide substrate
Christian Schlieker, W. Weihofen, E. Frijns, L. Kattenhorn +2 more
20070 citations
Semantic Scholar

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