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M. Valdearcos · SciRah

Researcher profile · Semantic Scholar

M. Valdearcos

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M. Valdearcos — researcher profile on SciRah

h-index: 21
Works: 37
Citations: 2,678

Most-cited papers

Microglia Dictate the Impact of Saturated Fat Consumption on Hypothalamic Inflammation and Neuronal Function
M. Valdearcos, M. Robblee, D. I. Benjamin, D. Nomura +2 more
2014Cell Reports572 citations Open access
Semantic Scholar
Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice.
Xiaomei Feng, M. Valdearcos, Yosuke Uchida, David Lutrin +2 more
2017JCI Insight332 citations Open access
Semantic Scholar
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility
M. Valdearcos, J. Douglass, M. Robblee, M. Dorfman +7 more
2017Cell Metabolism308 citations Open access
Semantic Scholar
Saturated fatty acids engage an IRE1α-dependent pathway to activate the NLRP3 inflammasome in myeloid cells
M. Robblee, Charles C. Kim, Jess Porter Abate, M. Valdearcos +5 more
2016Cell Reports187 citations Open access
Semantic Scholar
Hypothalamic inflammation in the control of metabolic function.
M. Valdearcos, Allison W. Xu, S. Koliwad
2015Annual Review of Physiology185 citations Open access
Semantic Scholar
Microglial Inflammatory Signaling Orchestrates the Hypothalamic Immune Response to Dietary Excess and Mediates Obesity Susceptibility.
M. Valdearcos, J. Douglass, M. Robblee, M. Dorfman +7 more
2018Cell Metabolism174 citations Open access
Semantic Scholar
Interleukin‐6 is both necessary and sufficient to produce perioperative neurocognitive disorder in mice
Jun Hu, Xiaomei Feng, M. Valdearcos, David Lutrin +3 more
2018British Journal of Anaesthesia136 citations Open access
Semantic Scholar
mTORC1 to AMPK switching underlies β-cell metabolic plasticity during maturation and diabetes.
Rami Jaafar, S. Tran, Ajit Shah, Gao Sun +12 more
2019Journal of Clinical Investigation109 citations Open access
Semantic Scholar
Lipin-2 Reduces Proinflammatory Signaling Induced by Saturated Fatty Acids in Macrophages*
M. Valdearcos, E. Esquinas, C. Meana, Lucía Peña +3 more
2012Journal of Biological Chemistry102 citations Open access
Semantic Scholar
Subcellular Localization and Role of Lipin-1 in Human Macrophages
M. Valdearcos, E. Esquinas, C. Meana, Luis Gil-de-Gómez +3 more
2011Journal of Immunology97 citations Open access
Semantic Scholar
Requirement of JNK-Mediated Phosphorylation for Translocation of Group IVA Phospholipase A2 to Phagosomes in Human Macrophages1
J. Casas, C. Meana, E. Esquinas, M. Valdearcos +3 more
2009Journal of Immunology69 citations Open access
Semantic Scholar
Acute lesioning and rapid repair of hypothalamic neurons outside the blood-brain barrier
E. Yulyaningsih, Ivan A. Rudenko, M. Valdearcos, Emma Dahlén +6 more
2017Cell Reports53 citations Open access
Semantic Scholar
Obesity-associated microglial inflammatory activation paradoxically improves glucose tolerance
J. Douglass, K. Ness, M. Valdearcos, A. Wyse-Jackson +9 more
2023Cell Metabolism45 citations Open access
Semantic Scholar
Hypothalamic microglia as potential regulators of metabolic physiology
M. Valdearcos, Martin G. Jr Myers, S. Koliwad
2019Nature Metabolism44 citations
Semantic Scholar
Microglial Lipid Biology in the Hypothalamic Regulation of Metabolic Homeostasis
Andrew Folick, S. Koliwad, M. Valdearcos
2021Frontiers in Endocrinology41 citations Open access
Semantic Scholar
Leptin potentiates astrogenesis in the developing hypothalamus
Daniele M. Rottkamp, Ivan A. Rudenko, Matthew T. Maier, Sahar Roshanbin +6 more
2015Molecular Metabolism36 citations Open access
Semantic Scholar
RORγt eTACs mediate oral tolerance and Treg induction.
Im-Hong Sun, A. E. Qualls, Han S Yin, Jia-Xi Wang +10 more
2025Journal of Experimental Medicine35 citations Open access
Semantic Scholar
The cationic cluster of group IVA phospholipase A2 (Lys488/Lys541/Lys543/Lys544) is involved in translocation of the enzyme to phagosomes in human macrophages
J. Casas, M. Valdearcos, J. Pindado, Jesús Balsinde +1 more
2010Journal of Lipid Research34 citations Open access
Semantic Scholar
Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity.
Lucía Peña, C. Meana, A. Astudillo, Gema Lordén +5 more
2016Biochimica et Biophysica Acta29 citations Open access
Semantic Scholar
Blocking Kv1.3 potassium channels psrevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice.
Leng K Lai, M. Valdearcos, Kazuhito Morioka, S. Saxena +10 more
2020British Journal of Anaesthesia28 citations Open access
Semantic Scholar
Metabolic factors in the regulation of hypothalamic innate immune responses in obesity
Andrew Folick, Rachel T. Cheang, M. Valdearcos, S. Koliwad
2022Experimental and Molecular Medicine21 citations Open access
Semantic Scholar
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis
Eirini Vagena, Jasmina Crneta, Pauline Engström, Li He +13 more
2022Science Signaling15 citations Open access
Semantic Scholar
Microglia mediate the early-life programming of adult glucose control
M. Valdearcos, Emily R. McGrath, Stephen M. Brown Mayfield, Melissa G. Jacuinde +7 more
2025Cell Reports11 citations Open access
Semantic Scholar
Identification of AgRP cells in the murine hindbrain that drive feeding
Tomas P. Bachor, Eunsang Hwang, E. Yulyaningsih, Kush Attal +9 more
2024Molecular Metabolism9 citations Open access
Semantic Scholar
Glycation-lowering compounds inhibit ghrelin signaling to reduce food intake, lower insulin resistance, and extend lifespan
Lauren A. Wimer, K. Kaneshiro, J. Ramirez, Neelanjan Bose +14 more
2024bioRxiv5 citations Open access
Semantic Scholar
Microglia mediate the early-life programming of adult glucose control
M. Valdearcos, E. McGrath, SM Brown Mayfield, A. Folick +6 more
2024bioRxiv5 citations
Semantic Scholar
Stress and Microglia: A Double-edged Relationship.
J. Delpech, M. Valdearcos, A. Nadjar
2024Advances in neurobiology2 citations
Semantic Scholar
Microglial inflammatory activation paradoxically improves glucose tolerance during diet-induced obesity
J. Douglass, M. Valdearcos, K. Ness, A. Wyse-Jackson +8 more
2022bioRxiv1 citations Open access
Semantic Scholar
Microglia Activation Regulates Systemic Glucose Tolerance
J. Douglass, M. Valdearcos, S. Koliwad, Joshua P. Thaler
2018Diabetes1 citations
Semantic Scholar
ApoE-Dependent Lipid Handling by Median Eminence Microglia Preserves Myelin Integrity and Metabolic Function
E. McGrath, A. Folick, LJ Morrissette, SM Brown Mayfield +9 more
2026bioRxiv0 citations Open access
Semantic Scholar
Q&A with Suneil Koliwad and Martin Valdearcos.
S. Koliwad, M. Valdearcos
2025Cell Reports0 citations Open access
Semantic Scholar
Corrigendum to 'Blocking Kv1.3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice' (Br J Anaesth 2020; 125: 298-307).
I. K. Lai, M. Valdearcos, Kazuhito Morioka, S. Saxena +10 more
2025British Journal of Anaesthesia0 citations
Semantic Scholar
Epigenetic regulation of the aryl hydrocarbon receptor (AhR) in normal aging. Defining The Role of Cellular Resilience in Baboon Aging. Mitochondrial dysfunction contributes to fibrosis in aging-associated benign prostatic hyperplasia (BPH)
Jeremy A. Whitson, M. Martín-Pérez, A. Bitto, G. Merrihew +26 more
20220 citations
Semantic Scholar
Brief communication Leptin potentiates astrogenesis in the developing hypothalamus
Daniele M. Rottkamp, Ivan A. Rudenko, Matthew T. Maier, Sahar Roshanbin +6 more
20150 citations
Semantic Scholar
Lipin-1 controls phospholipase A2 activation in human macrophages
M. Balboa, M. Valdearcos, E. Esquinas
20130 citations
Semantic Scholar
This information is current as in Human Macrophages Subcellular Localization and Role of Lipin-1
Balboa, Gil-de-Gómez, C. Guijas, Jesús Balsinde +4 more
20110 citations
Semantic Scholar
Subcellular Localization and Role of Lipin-1
Balboa, Gil-de-Gómez, C. Guijas, Jesús Balsinde +4 more
20110 citations
Semantic Scholar

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