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A. Oberst · SciRah

Researcher profile · Semantic Scholar

A. Oberst

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A. Oberst — researcher profile on SciRah

h-index: 49
Works: 94
Citations: 19K

Most-cited papers

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L. Galluzzi, I. Vitale, S. Aaronson, J. Abrams +165 more
2018Cell Death and Differentiation6,082 citations Open access
Semantic Scholar
Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis
A. Oberst, C. Dillon, R. Weinlich, L. McCormick +5 more
2011Nature1,284 citations Open access
Semantic Scholar
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
L. Galluzzi, J. M. Bravo-San Pedro, I. Vitale, S. Aaronson +104 more
2014Cell Death and Differentiation985 citations Open access
Semantic Scholar
Necroptosis in development, inflammation and disease
R. Weinlich, A. Oberst, H. Beere, D. Green
2016Nature reviews. Molecular cell biology921 citations
Semantic Scholar
Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells
Jennifer Martinez, Johann Almendinger, A. Oberst, Rachel A. Ness +4 more
2011Proceedings of the National Academy of Sciences of the United States of America651 citations Open access
Semantic Scholar
RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8+ T cells
N. Yatim, H. Jusforgues-Saklani, Susana L. Orozco, O. Schulz +5 more
2015Science588 citations Open access
Semantic Scholar
CASPASE 8 inhibits programmed necrosis by processing CYLD
M. A. O'Donnell, E. Pérez-Jiménez, A. Oberst, A. Ng +4 more
2011Nature Cell Biology506 citations Open access
Semantic Scholar
Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death
G. Ichim, Jonathan Lopez, S. Ahmed, Nathiya Muthalagu +16 more
2015Molecules and Cells443 citations Open access
Semantic Scholar
Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis
Diego A. Rodriguez, R. Weinlich, Scott A. Brown, C. Guy +8 more
2015Cell Death and Differentiation366 citations Open access
Semantic Scholar
Intratumoral activation of the necroptotic pathway components RIPK1 and RIPK3 potentiates anti-tumor immunity
Annelise G. Snyder, Nicholas W. Hubbard, Michelle N. Messmer, Sigal B. Kofman +6 more
2019Science immunology348 citations Open access
Semantic Scholar
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I. Vitale, F. Pietrocola, E. Guilbaud, S. Aaronson +224 more
2023Cell Death and Differentiation346 citations Open access
Semantic Scholar
RIPK3 activates parallel pathways of MLKL-driven necroptosis and FADD-mediated apoptosis to protect against influenza A virus
Shoko Nogusa, Roshan J. Thapa, C. Dillon, Swantje Liedmann +18 more
2016Cell Host and Microbe339 citations Open access
Semantic Scholar
Survival function of the FADD-CASPASE-8-cFLIPL complex
C. Dillon, A. Oberst, R. Weinlich, L. Janke +5 more
2012Cell Reports336 citations Open access
Semantic Scholar
Widespread mitochondrial depletion via mitophagy does not compromise necroptosis
S. Tait, A. Oberst, Giovanni Quarato, S. Milasta +12 more
2013Cell Reports301 citations Open access
Semantic Scholar
The nucleotide sensor ZBP1 and kinase RIPK3 induce the enzyme IRG1 to promote an antiviral metabolic state in neurons
B. Daniels, Sigal B. Kofman, Julian R. Smith, Geoffrey T. Norris +8 more
2019Immunity289 citations Open access
Semantic Scholar
RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis
Susana L. Orozco, N. Yatim, M. Werner, H. Tran +5 more
2014Cell Death and Differentiation287 citations Open access
Semantic Scholar
Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling
Naomi H Philip, C. Dillon, Annelise G. Snyder, Patrick Fitzgerald +13 more
2014Proceedings of the National Academy of Sciences of the United States of America280 citations Open access
Semantic Scholar
Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
Seokwon Kang, T. Fernandes-Alnemri, Corey Rogers, Lindsey Mayes +11 more
2015Nature Communications256 citations Open access
Semantic Scholar
Mitochondrial permeabilisation engages NF-κB dependent anti-tumour activity under caspase deficiency
E. Giampazolias, B. Zunino, S. Dhayade, Florian J. Bock +23 more
2017Nature Cell Biology236 citations Open access
Semantic Scholar
MLKL activation triggers NLRP3-mediated processing and release of IL-1β independent of gasdermin-D
K. Gutierrez, Michael A. Davis, B. Daniels, T. Olsen +4 more
2017Journal of Immunology227 citations Open access
Semantic Scholar
FLIPL induces caspase-8 activity in the absence of interdomain caspase-8 cleavage and alters substrate specificity
C. Pop, A. Oberst, M. Drąg, B. V. van Raam +3 more
2011Biochemical Journal224 citations Open access
Semantic Scholar
Living with death: the evolution of the mitochondrial pathway of apoptosis in animals
A. Oberst, C. Bender, D. Green
2008Cell Death and Differentiation220 citations Open access
Semantic Scholar
Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation*
A. Oberst, C. Pop, Alexandre Tremblay, Véronique Blais +3 more
2010Journal of Biological Chemistry208 citations Open access
Semantic Scholar
ADAR1 mutation causes ZBP1-dependent immunopathology
Nicholas W. Hubbard, Joshua M. Ames, M. Maurano, Lan H. Chu +8 more
2022Nature194 citations Open access
Semantic Scholar
Intracellular nucleic acid sensing triggers necroptosis through synergistic type-I interferon and TNF signaling
Michelle Brault, T. Olsen, Jennifer Martinez, Daniel B. Stetson +1 more
2018Journal of Immunology180 citations Open access
Semantic Scholar
RIPK-dependent necrosis and its regulation by caspases: A mystery in five acts
D. Green, A. Oberst, C. Dillon, R. Weinlich +1 more
2011Molecules and Cells174 citations Open access
Semantic Scholar
RIPK3 restricts viral pathogenesis via cell death-independent neuroinflammation
B. Daniels, Annelise G. Snyder, T. Olsen, Susana L. Orozco +6 more
2017Cell167 citations Open access
Semantic Scholar
It cuts both ways: reconciling the dual roles of caspase-8 in cell death and survival
A. Oberst, D. Green
2011Nature reviews. Molecular cell biology167 citations Open access
Semantic Scholar
Cutting Edge: Endoplasmic Reticulum Stress Licenses Macrophages To Produce Mature IL-1β in Response to TLR4 Stimulation through a Caspase-8– and TRIF-Dependent Pathway
K. Shenderov, N. Riteau, R. Yip, K. Mayer-Barber +8 more
2014Journal of Immunology158 citations Open access
Semantic Scholar
Characterization of cytoplasmic caspase-2 activation by induced proximity
L. Bouchier-Hayes, A. Oberst, Gavin Peter McStay, Samuel A. Connell +5 more
2009Molecules and Cells155 citations Open access
Semantic Scholar
Cells, Gels, and the Engines of Life
A. Oberst
2003Cell Death and Differentiation152 citations
Semantic Scholar
Protective roles for caspase-8 and cFLIP in adult homeostasis
R. Weinlich, A. Oberst, C. Dillon, L. Janke +7 more
2013Cell Reports149 citations Open access
Semantic Scholar
Ubiquitin-dependent Degradation of p73 Is Inhibited by PML
F. Bernassola, P. Salomoni, A. Oberst, C. D. di Como +3 more
2004Journal of Experimental Medicine129 citations Open access
Semantic Scholar
The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch
A. Oberst, M. Malatesta, R. Aqeilan, M. Rossi +8 more
2007Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
Programmed Cell Death and Inflammation: Winter is Coming
J. Kolb, Thomas H. Oguin, A. Oberst, Jennifer Martinez
2017Trends in immunology115 citations Open access
Semantic Scholar
Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels
J. Thorburn, Z. Andrysik, Leah Staskiewicz, Jacob M. Gump +5 more
2014Cell Reports115 citations Open access
Semantic Scholar
The Antisocial Network: Cross Talk Between Cell Death Programs in Host Defense
Annelise G. Snyder, A. Oberst
2021Annual Review of Immunology111 citations Open access
Semantic Scholar
RIPK3 in cell death and inflammation: The Good, the Bad, and the Ugly
Susana L. Orozco, A. Oberst
2017Immunological Reviews110 citations Open access
Semantic Scholar
RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity
Susana L. Orozco, B. Daniels, N. Yatim, Michelle N. Messmer +10 more
2019Cell Reports108 citations Open access
Semantic Scholar
Comparing the effects of different cell death programs in tumor progression and immunotherapy
Michelle N. Messmer, Annelise G. Snyder, A. Oberst
2018Cell Death and Differentiation100 citations Open access
Semantic Scholar
T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity
A. Jain, Ricardo A. Irizarry-Caro, Margaret M. McDaniel, A. Chawla +7 more
2019Nature Immunology93 citations Open access
Semantic Scholar
Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death
Naomi H Philip, Alexandra A DeLaney, Lance W Peterson, Melanie Santos-Marrero +13 more
2016PLoS Pathogens92 citations Open access
Semantic Scholar
Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1
Ruoshi Peng, C. Wang, Wang-Kan Xuan, M. Idorn +14 more
2022EMBO Reports86 citations Open access
Semantic Scholar
Regulation of the p73 protein stability and degradation.
A. Oberst, M. Rossi, P. Salomoni, P. Pandolfi +3 more
2005Biochemical and Biophysical Research Communications - BBRC70 citations
Semantic Scholar
NPM1 directs PIDDosome-dependent caspase-2 activation in the nucleolus
Kiyohiro Ando, M. J. Parsons, Richa B. Shah, Chloé I. Charendoff +8 more
2017Journal of Cell Biology65 citations Open access
Semantic Scholar
Mito-priming as a method to engineer Bcl-2 addiction
Jonathan Lopez, Margaux Bessou, Joel S. Riley, E. Giampazolias +7 more
2016Nature Communications60 citations Open access
Semantic Scholar
Ubiquitination and proteasomal degradation of ATG12 regulates its proapoptotic activity
M. Haller, A. Hock, E. Giampazolias, A. Oberst +5 more
2014Autophagy59 citations Open access
Semantic Scholar
Controlled Detonation: Evolution of Necroptosis in Pathogen Defense
Michelle Brault, A. Oberst
2016Immunology and Cell Biology54 citations Open access
Semantic Scholar
Death in the fast lane: What’s next for necroptosis?
A. Oberst
2015The FEBS Journal50 citations Open access
Semantic Scholar
The promyelocytic leukaemia protein tumour suppressor functions as a transcriptional regulator of p63
F. Bernassola, A. Oberst, G. Melino, P. Pandolfi
2005Oncogene47 citations Open access
Semantic Scholar

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