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Z. Andrysik · SciRah

Researcher profile · Semantic Scholar

Z. Andrysik

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Z. Andrysik — researcher profile on SciRah

h-index: 25
Works: 52
Citations: 2,373

Most-cited papers

Mechanisms of transcriptional regulation by p53
Kelly D. Sullivan, M. Galbraith, Z. Andrysik, Joaquín M. Espinosa
2017Cell Death and Differentiation404 citations Open access
Semantic Scholar
Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms
M. Allen, Z. Andrysik, V. L. Dengler, H. Mellert +8 more
2014eLife241 citations Open access
Semantic Scholar
Autophagy inhibition mediates apoptosis sensitization in cancer therapy by relieving FOXO3a turnover
Brent E. Fitzwalter, C. Towers, Kelly D. Sullivan, Z. Andrysik +7 more
2018Developmental Cell193 citations Open access
Semantic Scholar
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity
Z. Andrysik, M. Galbraith, A. Guarnieri, S. Zaccara +5 more
2017Genome Research154 citations Open access
Semantic Scholar
Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels
J. Thorburn, Z. Andrysik, Leah Staskiewicz, Jacob M. Gump +5 more
2014Cell Reports115 citations Open access
Semantic Scholar
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus
Z. Andrysik, William Z. Bernstein, L. Deng, David L. Myer +4 more
2010Nucleic Acids Research96 citations Open access
Semantic Scholar
Activation of the aryl hydrocarbon receptor is the major toxic mode of action of an organic extract of a reference urban dust particulate matter mixture: the role of polycyclic aromatic hydrocarbons.
Z. Andrysik, J. Vondráček, S. Marvanová, M. Cigánek +7 more
2011Mutation research95 citations
Semantic Scholar
CDK8 kinase activity promotes glycolysis
M. Galbraith, Z. Andrysik, A. Pandey, Maria Hoh +4 more
2017Cell Reports83 citations Open access
Semantic Scholar
Transcriptional responses to IFN-γ require Mediator kinase-dependent pause release and mechanistically distinct functions of CDK8 and CDK19
Iris Steinparzer, V. Sedlyarov, Jonathan D. Rubin, Kevin Eislmayr +14 more
2019Molecules and Cells82 citations Open access
Semantic Scholar
The aryl hydrocarbon receptor-dependent deregulation of cell cycle control induced by polycyclic aromatic hydrocarbons in rat liver epithelial cells.
Z. Andrysik, J. Vondráček, M. Machala, P. Krĉmár̂ +6 more
2007Mutation research78 citations
Semantic Scholar
Triplication of the interferon receptor locus contributes to hallmarks of Down syndrome in a mouse model
Katherine A. Waugh, Ross Minter, Jessica Baxter, Congwu Chi +28 more
2023Nature Genetics72 citations Open access
Semantic Scholar
A genetic screen identifies TCF3/E2A and TRIAP1 as pathway-specific regulators of the cellular response to p53 activation
Z. Andrysik, Jihye Kim, A. Tan, Joaquín M. Espinosa
2013Cell Reports69 citations Open access
Semantic Scholar
The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L
Alice C. Guarnieri, CG Towers, DJ Drasin, Muj Oliphant +8 more
2018Oncogene63 citations Open access
Semantic Scholar
Multi-omics analysis reveals contextual tumor suppressive and oncogenic gene modules within the acute hypoxic response
Z. Andrysik, Heather Bender, M. Galbraith, Joaquín M. Espinosa
2021Nature Communications56 citations Open access
Semantic Scholar
ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas
Christopher G. Abraham, Michael P Ludwig, Z. Andrysik, A. Pandey +4 more
2018Cell Reports47 citations Open access
Semantic Scholar
JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome
Kathryn D. Tuttle, Katherine A. Waugh, Paula Araya, Ross Minter +12 more
2020Cell Reports42 citations Open access
Semantic Scholar
7H-Dibenzo[c,g]carbazole and 5,9-dimethyldibenzo[c,g]carbazole exert multiple toxic events contributing to tumor promotion in rat liver epithelial 'stem-like' cells.
J. Vondráček, Lenka Švihálková-Šindlerová, K. Pěnčíková, P. Krĉmár̂ +7 more
2006Mutation research42 citations
Semantic Scholar
A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerization of poised BAX
R. Henry, Z. Andrysik, Ramiro París, M. Galbraith +1 more
2012EMBO Journal40 citations Open access
Semantic Scholar
Aryl hydrocarbon receptor-mediated disruption of contact inhibition is associated with connexin43 downregulation and inhibition of gap junctional intercellular communication
Z. Andrysik, J. Procházková, M. Kabátková, Lenka Umannová +5 more
2012Archives of Toxicology37 citations
Semantic Scholar
Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30
D. Rizzotto, S. Zaccara, A. Rossi, M. Galbraith +7 more
2020Cell Reports31 citations Open access
Semantic Scholar
Determination of Azidothymidine – an Antiproliferative and Virostatic Drug by Square‐Wave Voltammetry
J. Vacek, Z. Andrysik, L. Trnková, R. Kizek
200429 citations
Semantic Scholar
PPM1D suppresses p53-dependent transactivation and cell death by inhibiting the Integrated Stress Response
Z. Andrysik, Kelly D. Sullivan, J. Kieft, Joaquín M. Espinosa
2022Nature Communications28 citations Open access
Semantic Scholar
Dimethyl sulfoxide potentiates death receptor-mediated apoptosis in the human myeloid leukemia U937 cell line through enhancement of mitochondrial membrane depolarization.
J. Vondráček, K. Souček, M. Sheard, K. Chramostová +3 more
2006Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis27 citations
Semantic Scholar
The 2,2',4,4',5,5'-hexachlorobiphenyl-enhanced degradation of connexin 43 involves both proteasomal and lysosomal activities.
P. Šimečková, J. Vondráček, Z. Andrysik, Jiřina Zatloukalová +3 more
2009Toxicological Sciences26 citations Open access
Semantic Scholar
Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer
Enerlyn Lozada, Z. Andrysik, M. Yin, Nicholas Redilla +2 more
2016OncoTarget25 citations Open access
Semantic Scholar
Activation of ERK1/2 and p38 kinases by polycyclic aromatic hydrocarbons in rat liver epithelial cells is associated with induction of apoptosis.
Z. Andrysik, M. Machala, K. Chramostová, J. Hofmanová +2 more
2006Toxicology and Applied Pharmacology25 citations
Semantic Scholar
Apoptosis and inhibition of gap-junctional intercellular communication induced by LA-12, a novel hydrophobic platinum(IV) complex.
L. Procházka, J. Turánek, R. Tesařík, P. Knotigová +7 more
2007Archives of Biochemistry and Biophysics23 citations
Semantic Scholar
Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands.
J. Procházková, Simona Strapáčová, Lucie Svržková, Z. Andrysik +9 more
2018Toxicology Letters22 citations
Semantic Scholar
Inhibition of Aryl Hydrocarbon Receptor (AhR) Expression Disrupts Cell Proliferation and Alters Energy Metabolism and Fatty Acid Synthesis in Colon Cancer Cells
M. Karasová, J. Procházková, Z. Tylichová, R. Fedr +9 more
2022Cancers20 citations Open access
Semantic Scholar
Harnessing p53 for targeted cancer therapy: new advances and future directions
Z. Andrysik, J. Espinosa
2025Transcription18 citations Open access
Semantic Scholar
Cell differentiation modifies the p53 transcriptional program through a combination of gene silencing and constitutive transactivation
Roubina Tatavosian, Micah G Donovan, M. Galbraith, H. N. Duc +10 more
2023Cell Death and Differentiation18 citations Open access
Semantic Scholar
A prolonged exposure of human lung carcinoma epithelial cells to benzo[a]pyrene induces p21-dependent epithelial-to-mesenchymal transition (EMT)-like phenotype.
M. Hýžďalová, J. Procházková, Simona Strapáčová, Lucie Svržková +11 more
2021Chemosphere15 citations
Semantic Scholar
Non-dioxin-like polychlorinated biphenyls induce a release of arachidonic acid in liver epithelial cells: a partial role of cytosolic phospholipase A(2) and extracellular signal-regulated kinases 1/2 signalling.
Lenka Umannová, J. Neĉa, Z. Andrysik, J. Vondráček +5 more
2008Toxicology14 citations Open access
Semantic Scholar
Multiple biological effects of inhibitors of arachidonic acid metabolism on human keratinocytes
J. Pacherník, A. Hampl, K. Souček, M. Kovaříková +3 more
2002Archives of Dermatological Research12 citations
Semantic Scholar
JAK1 inhibition blocks lethal sterile immune responses: implications for COVID-19 therapy
Kathryn D. Tuttle, Ross Minter, Katherine A. Waugh, Paula Araya +9 more
2020bioRxiv9 citations Open access
Semantic Scholar
Antimigraine Drug Avitriptan Is a Ligand and Agonist of Human Aryl Hydrocarbon Receptor that Induces CYP1A1 in Hepatic and Intestinal Cells
Barbora Vyhlídalová, Kristýna Krasulová, Petra Pečinková, Karolína Poulíková +5 more
2020International Journal of Molecular Sciences8 citations Open access
Semantic Scholar
FAM193A is a positive regulator of p53 activity
Maria M. Szwarc, A. Guarnieri, Molishree Joshi, H. N. Duc +9 more
2023Cell Reports6 citations Open access
Semantic Scholar
Interferon receptor gene dosage determines diverse hallmarks of Down syndrome
Katherine A. Waugh, Ross Minter, Jessica Baxter, Congwu Chi +27 more
2022bioRxiv5 citations Open access
Semantic Scholar
Global Analyses to Identify Direct Transcriptional Targets of p53.
M. Galbraith, Z. Andrysik, Kelly D. Sullivan, Joaquín M. Espinosa
2021Methods in molecular biology3 citations
Semantic Scholar
Author response: Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms
M. Allen, Z. Andrysik, Z. Andrysik, V. L. Dengler +16 more
20142 citations Open access
Semantic Scholar
Progressive deterioration of adaptive immune repertoires in Down syndrome linked to interferon hyperactivity and lymphoid tissue disorganization
Micah G. Donovan, N. Eduthan, Brian F. Niemeyer, E. Woods +15 more
2026bioRxiv0 citations Open access
Semantic Scholar
p53-induced apoptosis is specified by a translation program regulated by PCBP2 and DHX30
D. Rizzotto, S. Zaccara, A. Rossi, M. Galbraith +7 more
2019bioRxiv0 citations Open access
Semantic Scholar
PO-077 Identification of DHX30 as an inhibitor of the translation of pro-apoptotic mRNAS after P53 activation by nutlin
D. Rizzotto, S. Zaccara, E. Dassi, M. Galbraith +6 more
2018ESMO Open0 citations Open access
Semantic Scholar
A DR4:tBID axis drives the p53 apoptotic response by promoting oligomerisation of poised BAX
R. Henry, Z. Andrysik, Ramiro París, Matthew Galbraith +1 more
20110 citations
Semantic Scholar
Retinoic acid affects the response of v-Myb-transformedmonoblasts to okadaic acid
P. Beneš, Vendula Macečková, Z. Andrysik, Jiřina Zatloukalová +1 more
20060 citations
Semantic Scholar
Okadaická kyselina indukuje diferenciaci a apoptózu monoblastůBM2
Petr Beneš, Vendula Macečková, Z. Andrysik, Jiřina Zatloukalová +1 more
20060 citations
Semantic Scholar
Toxic modes of action of polychlorinated biphenyls in livercells
M. Machala, L. Bláha, K. Chramostová, M. Plíšková +3 more
20030 citations
Semantic Scholar
447 Acute exposure to polycyclic aromatic hydrocarbons affects multiple cell signaling components in rat liver epithelial cell line
M. Machala, L. Bláha, Petra Kapplová, K. Pěnčíková +4 more
20030 citations
Semantic Scholar
449 AHR-activating polycyclic aromatic hydrocarbons induce a release from contact inhibition or apoptosis in rat liver epithelial cell line
J. Vondráček, Z. Andrysik, K. Chramostová, B. Vojtěšek +3 more
20030 citations
Semantic Scholar
Stanovení azidothymidinu v lidské moči, krevním séru a krvi
J. Vacek, Z. Andrysik, Libuše Trnková, Vojtěch Adam +1 more
20020 citations
Semantic Scholar

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Joaquín M. Espinosa×23
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Joaquín M. Espinosa — researcher profile on SciRah
M. Galbraith×19
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M. Galbraith — researcher profile on SciRah
Kelly D. Sullivan×17
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J. Vondráček×14
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M. Machala — researcher profile on SciRah

A. Kozubík×11

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Michael P Ludwig×6

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A. Guarnieri×5

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K. Pěnčíková×5

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K. Chramostová×5

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