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Shuenn-Chen Yang · SciRah

Researcher profile · Semantic Scholar

Shuenn-Chen Yang

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Shuenn-Chen Yang — researcher profile on SciRah

h-index: 29
Works: 50
Citations: 3,643

Most-cited papers

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug
Shu-Ping Wang, Wen-Lung Wang, Yih-Leong Chang, Chen-Tu Wu +9 more
2009Nature Cell Biology466 citations
Semantic Scholar
Selection of invasive and metastatic subpopulations from a human lung adenocarcinoma cell line.
Y. Chu, Pan-Chyr Yang, Shuenn-Chen Yang, Y. Shyu +3 more
1997American Journal of Respiratory Cell and Molecular Biology435 citations
Semantic Scholar
MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1
Ching-Wen Lin, Yih-Leong Chang, Yuting Chang, Jau-Chen Lin +7 more
2013Nature Communications290 citations Open access
Semantic Scholar
Transcription Repressor Slug Promotes Carcinoma Invasion and Predicts Outcome of Patients with Lung Adenocarcinoma
J. Shih, Meng-Feng Tsai, Tzu-Hua Chang, Yih-Leong Chang +11 more
2005Clinical Cancer Research222 citations
Semantic Scholar
Targeting Neuropilin 1 as an Antitumor Strategy in Lung Cancer
T. Hong, Yuh-Ling Chen, Yi-Ying Wu, A. Yuan +8 more
2007Clinical Cancer Research201 citations Open access
Semantic Scholar
Global analysis of gene expression in invasion by a lung cancer model.
J. Chen, K. Peck, T. Hong, Shuenn-Chen Yang +7 more
2001Cancer Research200 citations
Semantic Scholar
Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer.
Chi-Tai Yeh, Alexander T. H. Wu, P. Chang, Kuan-Yu Chen +16 more
2012American Journal of Respiratory and Critical Care Medicine188 citations
Semantic Scholar
Claudin-1 is a metastasis suppressor and correlates with clinical outcome in lung adenocarcinoma.
Yu-Chih Chao, Szu-Hua Pan, Shuenn-Chen Yang, Sung-Liang Yu +9 more
2009American Journal of Respiratory and Critical Care Medicine179 citations Open access
Semantic Scholar
Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells.
J. Shih, Shuenn-Chen Yang, T. Hong, A. Yuan +7 more
2001Journal of the National Cancer Institute157 citations Open access
Semantic Scholar
Highly specific in vivo gene delivery for p53-mediated apoptosis and genetic photodynamic therapies of tumour
S. Tseng, Zi-Xian Liao, Shih-Han Kao, Yi-Fang Zeng +8 more
2015Nature Communications95 citations Open access
Semantic Scholar
PM2.5 promotes lung cancer progression through activation of the AhR‐TMPRSS2‐IL18 pathway
Tong-Hong Wang, Kuo-Yen Huang, Chin-Chuan Chen, Ya-Hsuan Chang +6 more
2023EMBO Molecular Medicine89 citations Open access
Semantic Scholar
Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis
Ching-Wen Lin, Lu-Kai Wang, Shu-Ping Wang, Yi Chang +11 more
2016Nature Communications86 citations Open access
Semantic Scholar
Profiling the downstream genes of tumor suppressor PTEN in lung cancer cells by complementary DNA microarray.
T. Hong, Pan-Chyr Yang, Konan Peck, Jeremy J. W. Chen +3 more
2000American Journal of Respiratory Cell and Molecular Biology78 citations
Semantic Scholar
Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment
Ya-Ting Wang, Jocelyn Chen, Chou-Wei Chang, J. Jen +13 more
2017Journal of Clinical Investigation68 citations Open access
Semantic Scholar
The ability of LCRMP-1 to promote cancer invasion by enhancing filopodia formation is antagonized by CRMP-1.
Szu-Hua Pan, Yu-Chih Chao, Pei-Fang Hung, Hsuan-Yu Chen +16 more
2011Journal of Clinical Investigation68 citations Open access
Semantic Scholar
p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug
Shu-Ping Wang, Wen-Lung Wang, Yih-Leong Chang, Chen-Tu Wu +9 more
2009Nature Cell Biology59 citations Open access
Semantic Scholar
Phenanthrene-based tylophorine-1 (PBT-1) inhibits lung cancer cell growth through the Akt and NF-κB pathways
Jau-Chen Lin, Shuenn-Chen Yang, T. Hong, Sung-Liang Yu +5 more
2009Journal of Medicinal Chemistry53 citations Open access
Semantic Scholar
Collapsin response mediator protein-1: A novel invasion-suppressor gene
J. Shih, Yuan-Chii Lee, Shuenn-Chen Yang, T. Hong +2 more
2003Clinical and Experimental Metastasis53 citations
Semantic Scholar
The dual PI3K/mTOR inhibitor BEZ235 restricts the growth of lung cancer tumors regardless of EGFR status, as a potent accompanist in combined therapeutic regimens
Yi-Ying Wu, Hung‐Chang Wu, Jia-En Wu, Kuo-Yen Huang +6 more
2019Journal of experimental & clinical cancer research : CR47 citations Open access
Semantic Scholar
Tid1-L inhibits EGFR signaling in lung adenocarcinoma by enhancing EGFR Ubiquitinylation and degradation.
Chi-Yuan Chen, C. Jan, Jeng-Fan Lo, Shuenn-Chen Yang +5 more
2013Cancer Research44 citations Open access
Semantic Scholar
Monocarboxylate Transporter 4 Is a Therapeutic Target in Non-small Cell Lung Cancer with Aerobic Glycolysis Preference
Ting-Chun Kuo, Kuo-Yen Huang, Shuenn-Chen Yang, Sean Wu +7 more
2020Molecular Therapy: Oncolytics41 citations Open access
Semantic Scholar
Antitumor Agents 268. Design, Synthesis, and Mechanistic Studies of New 9-Substituted Phenanthrene-based Tylophorine Analogs as Potent Cytotoxic Agents
Xiao-ming Yang, Qian Shi, Yi-Nan Liu, Guiyu Zhao +5 more
2009Journal of Medicinal Chemistry41 citations Open access
Semantic Scholar
Efficacy of tracheal gas insufflation in acute respiratory distress syndrome with permissive hypercapnia.
Ping-Hung Kuo, Huey-Dong Wu, Chong-Jen Yu, Shuenn-Chen Yang +2 more
1996American Journal of Respiratory and Critical Care Medicine40 citations
Semantic Scholar
Extracellular delivery of modified oligonucleotide and superparamagnetic iron oxide nanoparticles from a degradable hydrogel triggered by tumor acidosis.
Ching-Wen Lin, S. Tseng, I. Kempson, Shuenn-Chen Yang +2 more
2013Biomaterials38 citations Open access
Semantic Scholar
Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response
Chia-Yi Lin, Kuo-Yen Huang, Shih-Han Kao, Ming-Shiu Lin +6 more
2023Science Advances36 citations Open access
Semantic Scholar
Antitumor Agents 288. Design, Synthesis, SAR, and Biological Studies of Novel Heteroatom-Incorporated Antofine and Cryptopleurine Analogs as Potent and Selective Antitumor Agents
Xiao-ming Yang, Qian Shi, Shuenn-Chen Yang, Chi-Yuan Chen +11 more
2011Journal of Medicinal Chemistry36 citations Open access
Semantic Scholar
Remote Control of Light-Triggered Virotherapy.
S. Tseng, Kuo-Yen Huang, I. Kempson, Shih-Han Kao +4 more
2016ACS Nano35 citations
Semantic Scholar
From midbody protein-protein interaction network construction to novel regulators in cytokinesis.
Tzu-Chi Chen, Sheng-An Lee, T. Hong, J. Shih +7 more
2009Journal of Proteome Research31 citations
Semantic Scholar
MDA-9/Syntenin-Slug transcriptional complex promote epithelial-mesenchymal transition and invasion/metastasis in lung adenocarcinoma
Lu-Kai Wang, Szu-Hua Pan, Yih-Leong Chang, Pei-Fang Hung +9 more
2015OncoTarget30 citations Open access
Semantic Scholar
The Antitumor Agent PBT-1 Directly Targets HSP90 and hnRNP A2/B1 and Inhibits Lung Adenocarcinoma Growth and Metastasis
Chi-Yuan Chen, Shuenn-Chen Yang, Kuo-Hsiung Lee, Xiao-ming Yang +7 more
2014Journal of Medicinal Chemistry29 citations Open access
Semantic Scholar
Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients.
Szu-Hua Pan, Yu-Chih Chao, Hsuan-Yu Chen, Pei-Fang Hung +8 more
2010Lung Cancer29 citations
Semantic Scholar
Vorinostat combined with brigatinib overcomes acquired resistance in EGFR-C797S-mutated lung cancer.
Chia-Yi Lin, Kuo-Yen Huang, Yi-Chun Lin, Shuenn-Chen Yang +9 more
2021Cancer Letters23 citations
Semantic Scholar
Antitumor Agents 295. E-ring Hydroxylated Antofine and Cryptopleurine Analogs as Antiproliferative Agents: Design, Synthesis, and Mechanistic Studies
Xiao-ming Yang, Qian Shi, Chin-Yu Lai, Chi-Yuan Chen +9 more
2012Journal of Medicinal Chemistry22 citations Open access
Semantic Scholar
Integrated Omics Analysis of Non-Small-Cell Lung Cancer Cells Harboring the EGFR C797S Mutation Reveals the Potential of AXL as a Novel Therapeutic Target in TKI-Resistant Lung Cancer
Tong-Hong Wang, Chih-Ching Wu, Kuo-Yen Huang, Y. Leu +3 more
2020Cancers20 citations Open access
Semantic Scholar
Modulation of the expression of the invasion-suppressor CRMP-1 by cyclooxygenase-2 inhibition via reciprocal regulation of Sp1 and C/EBPα
Cheng-Chung Wu, Jau-Chen Lin, Shuenn-Chen Yang, Chiu-Wen Lin +4 more
2008Molecular Cancer Therapeutics19 citations Open access
Semantic Scholar
Small Molecule T315 Promotes Casitas B-Lineage Lymphoma-Dependent Degradation of Epidermal Growth Factor Receptor via Y1045 Autophosphorylation.
Kuo-Yen Huang, Shih-Han Kao, Wen-Lung Wang, Chi-Yuan Chen +8 more
2016American Journal of Respiratory and Critical Care Medicine18 citations
Semantic Scholar
Elevated serum levels of mucin-associated antigen in patients with acute respiratory distress syndrome.
Jin-Yuan Shih, Shuenn-Chen Yang, Chong-Jen Yu, Heuy-Dong Wu +3 more
1997American Journal of Respiratory and Critical Care Medicine17 citations
Semantic Scholar
Antitumor Agents 283. Further Elaboration of Desmosdumotin C Analogs as Potent Antitumor Agents: Activation of Spindle Assembly Checkpoint as Possible Mode of Action
Kyoko Nakagawa-Goto, Pei-Chi Wu, K. Bastow, Shuenn-Chen Yang +7 more
2011Bioorganic & Medicinal Chemistry14 citations Open access
Semantic Scholar
Development of nanoparticles incorporated with quercetin and ACE2-membrane as a novel therapy for COVID-19
Jia-You Fang, Kuo-Yen Huang, Tong-Hong Wang, Zih-Chan Lin +7 more
2024Journal of Nanobiotechnology12 citations Open access
Semantic Scholar
4(1H)-quinolone derivatives overcome acquired resistance to anti-microtubule agents by targeting the colchicine site of β-tubulin.
Ming-Shiu Lin, T. Hong, Ting-Hung Chou, Shuenn-Chen Yang +9 more
2019European journal of medicinal chemistry12 citations
Semantic Scholar
Overcoming EGFR T790M-based Tyrosine Kinase Inhibitor Resistance with an Allele-specific DNAzyme
Wei-Yun Lai, Chi-Yuan Chen, Shuenn-Chen Yang, Jer-yuarn Wu +3 more
2014Molecular Therapy: Nucleic Acids9 citations Open access
Semantic Scholar
Psorachromene induces apoptosis and suppresses tumor growth in NSCLC cells harboring EGFR L858R/T790M/C797S
Tong-Hong Wang, Y. Leu, Chin-Chuan Chen, Hsin-Jung Li +3 more
2022Phytotherapy Research8 citations
Semantic Scholar
Corrigendum: Daxx inhibits hypoxia-induced lung cancer cell metastasis by suppressing the HIF-1α/HDAC1/Slug axis
Ching-Wen Lin, Lu-Kai Wang, Shu-Ping Wang, Yih-Leong Chang +11 more
2017Nature Communications6 citations Open access
Semantic Scholar
Effect of Processing on Precision of Composite Panels
Shuenn-Chen Yang, C.-K. Huang, Chung-An Chen
20034 citations
Semantic Scholar
PINK1-Mediated Inhibition of EGFR Dimerization and Activation Impedes EGFR-Driven Lung Tumorigenesis
E. Lin, Bo-Tsang Huang, Wei-Yun Lai, Y. Tseng +3 more
2021Cancer Research2 citations Open access
Semantic Scholar
Neuropilin-1 and lung cancer progression: Potential role of targeting neuropilin-1 as an anti-tumor strategy
Yuh-Ling Chen, Yi-Ying Wu, Yi-Chuan Chung, Yu-Chih Chao +5 more
20061 citations
Semantic Scholar
DISCOVERY THE NOVEL COMPOUND FOR OVERCOMING EGFR‐TKI RESISTANCE IN LUNG ADENOCARCINOMA
Chung-Chih Lin, Shuenn-Chen Yang, Pan-Chyr Yang, S. Andrés
2018Respirology (Carlton South. Print)0 citations
Semantic Scholar
METABOLIC PROFILING CLASSIFIES NON‐SMALL CELL LUNG CANCER CELLS INTO DIFFERENT SUBTYPES WITH DISTINCT SENSITIVITIES TO METABOLIC INHIBITIONS
Kuo-Yen Huang, Shuenn-Chen Yang, Yih, L. Chang +8 more
2018Respirology (Carlton South. Print)0 citations Open access
Semantic Scholar
COMPARABILITY OF AUTOMATED IMAGE CYTOMETRY RESULTS OF BRONCHIAL WASHINGS WITH MANUAL CYTOLOGY AND HISTOPATHOLOGY IN DIAGNOSIS OF LUNG CANCER AT LUNG CENTER OF THE PHILIPPINES
Chung-Chih Lin, Shuenn-Chen Yang, Pan-Chyr Yang
2018Respirology (Carlton South. Print)0 citations
Semantic Scholar
P-283 The lung cancer invasion/metastasis suppressor CRMP-1 is a novel intermediate filament-like cytoskeletal protein involved in cell invasion and cytokinesis
Shuenn-Chen Yang, T. Hong, J. Shih, Chi-Ying F. Huang +1 more
20030 citations
Semantic Scholar

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Pan-Chyr Yang×35
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Pan-Chyr Yang — researcher profile on SciRah
T. Hong×28
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T. Hong — researcher profile on SciRah
Yih-Leong Chang×11
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Yih-Leong Chang — researcher profile on SciRah
Kuo-Yen Huang×11
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Hsuan-Yu Chen — researcher profile on SciRah

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Chi-Yuan Chen×8

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Yu-Chih Chao×7

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Jau-Chen Lin×7

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Szu-Hua Pan — researcher profile on SciRah

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Yi-Ying Wu — researcher profile on SciRah