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L. Scapozza · SciRah

Researcher profile · Semantic Scholar

L. Scapozza

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L. Scapozza — researcher profile on SciRah

h-index: 47
Works: 245
Citations: 8,979

Most-cited papers

Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks
S. Sotiriou, Irene Kamileri, Natalia Lugli, K. Evangelou +12 more
2016Molecules and Cells247 citations Open access
Semantic Scholar
Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer
P. Nowak-Sliwinska, L. Scapozza, A. R. I. Altaba
2019Biochimica et biophysica acta. Reviews on cancer163 citations Open access
Semantic Scholar
From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation
Carlotta Cecchini, Sara Pannilunghi, S. Tardy, L. Scapozza
2021Frontiers in Chemistry151 citations Open access
Semantic Scholar
Naphthoquinone Derivatives Exert Their Antitrypanosomal Activity via a Multi-Target Mechanism
S. Pieretti, J. Haanstra, M. Mazet, R. Perozzo +11 more
2013PLoS Neglected Tropical Diseases100 citations Open access
Semantic Scholar
Targeted cutaneous delivery of ciclosporin A using micellar nanocarriers and the possible role of inter-cluster regions as molecular transport pathways.
M. Lapteva, Verena Santer, K. Mondon, Ilias Patmanidis +5 more
2014Journal of Controlled Release79 citations
Semantic Scholar
DDR1 role in fibrosis and its pharmacological targeting.
S. Moll, A. Desmoulière, M. Moeller, J. Pache +9 more
2019Biochimica et biophysica acta. Molecular cell research78 citations Open access
Semantic Scholar
OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease
Beatrice Paola Festa, Marine Berquez, A. Gassama, I. Amrein +11 more
2018Human Molecular Genetics57 citations Open access
Semantic Scholar
Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes
A. García-López, F. Tessaro, H. R. Jonker, A. Wacker +20 more
2018Nature Communications57 citations Open access
Semantic Scholar
Virtual screening: an in silico tool for interlacing the chemical universe with the proteome.
Y. Westermaier, X. Barril, L. Scapozza
2015Methods57 citations
Semantic Scholar
Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module.
Hai-Bin Wang, Wen-Ting Lo, Andreja Vujičić Žagar, F. Gulluni +4 more
2018Molecules and Cells52 citations Open access
Semantic Scholar
Differences in conformational dynamics between Plasmodium falciparum and human Hsp90 orthologues enable the structure-based discovery of pathogen-selective inhibitors.
Tai Wang, W. Bisson, P. Mäser, L. Scapozza +1 more
2014Journal of Medicinal Chemistry52 citations Open access
Semantic Scholar
Heat-stability study of various insulin types in tropical temperature conditions: New insights towards improving diabetes care
Béatrice Kaufmann, P. Boulle, F. Berthou, M. Fournier +9 more
2021PLoS ONE50 citations Open access
Semantic Scholar
Diapocynin, a Dimer of the NADPH Oxidase Inhibitor Apocynin, Reduces ROS Production and Prevents Force Loss in Eccentrically Contracting Dystrophic Muscle
H. M. Ismail, L. Scapozza, U. Ruegg, O. Dorchies
2014PLoS ONE50 citations Open access
Semantic Scholar
Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy
E. Gayi, L. Neff, Xènia Massana Muñoz, H. M. Ismail +7 more
2018Nature Communications46 citations Open access
Semantic Scholar
Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding
P. B. de Andrade, L. Neff, M. Štrosová, D. Arsenijevic +6 more
2015Frontiers in Physiology44 citations Open access
Semantic Scholar
A subset of N-substituted phenothiazines inhibits NADPH oxidases.
T. Seredenina, Gianpaolo Chiriano, Aleksandra Filippova, Z. Nayernia +6 more
2015Free Radical Biology & Medicine43 citations Open access
Semantic Scholar
RNA pentaloop structures as effective targets of regulators belonging to the RsmA/CsrA protein family
K. Lapouge, R. Perozzo, Justyna Iwaszkiewicz, C. Bertelli +4 more
2013RNA Biology43 citations Open access
Semantic Scholar
How ‘Protein-Docking’ Translates into the New Emerging Field of Docking Small Molecules to Nucleic Acids?
F. Tessaro, L. Scapozza
2020Molecules41 citations Open access
Semantic Scholar
NPM/ALK mutants resistant to ASP3026 display variable sensitivity to alternative ALK inhibitors but succumb to the novel compound PF-06463922
L. Mologni, M. Ceccon, A. Pirola, Gianpaolo Chiriano +3 more
2015OncoTarget39 citations Open access
Semantic Scholar
A Bioorthogonal Chemical Reporter of Viral Infection†
Anne B. Neef, L. Pernot, V. Schreier, L. Scapozza +1 more
2015Angewandte Chemie37 citations Open access
Semantic Scholar
Establishment and Validation of Whole-Cell Based Fluorescence Assays to Identify Anti-Mycobacterial Compounds Using the Acanthamoeba castellanii - Mycobacterium marinum Host-Pathogen System
Sébastien Kicka, Valentin Trofimov, Christopher F. Harrison, Hajer Ouertatani-Sakouhi +5 more
2014PLoS ONE36 citations Open access
Semantic Scholar
In Silico Driven Design and Synthesis of Rhodanine Derivatives as Novel Antibacterials Targeting the Enoyl Reductase InhA.
L. Slepikas, Gianpaolo Chiriano, R. Perozzo, S. Tardy +12 more
2016Journal of Medicinal Chemistry35 citations Open access
Semantic Scholar
Design, synthesis, and biological and crystallographic evaluation of novel inhibitors of Plasmodium falciparum enoyl-ACP-reductase (PfFabI).
Federica Belluti, R. Perozzo, L. Lauciello, Francesco Colizzi +9 more
2013Journal of Medicinal Chemistry34 citations Open access
Semantic Scholar
A Coincidence Detection Mechanism Controls PX-BAR Domain-Mediated Endocytic Membrane Remodeling via an Allosteric Structural Switch.
Wen-Ting Lo, Andreja Vujičić Žagar, F. Gerth, Martin Lehmann +6 more
2017Developmental Cell30 citations Open access
Semantic Scholar
Identification of Natural Products Inhibiting SARS-CoV-2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach
A. Wasilewicz, B. Kirchweger, D. Bojkova, Marie Jose Abi Saad +11 more
2023Journal of Natural Products29 citations Open access
Semantic Scholar
Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets
Valentin Trofimov, Sébastien Kicka, S. Mucaria, N. Hanna +8 more
2018Scientific Reports29 citations Open access
Semantic Scholar
CEMIP (HYBID, KIAA1199): structure, function and expression in health and disease
S. Spataro, Concetta Guerra, A. Cavalli, Jacopo Sgrignani +6 more
2022The FEBS Journal26 citations Open access
Semantic Scholar
Efficacy study of two novel hyaluronic acid-based formulations for viscosupplementation therapy in an early osteoarthrosic rabbit model.
S. Kaderli, E. Viguier, D. Watrelot-Virieux, T. Roger +5 more
2015European journal of pharmaceutics and biopharmaceutics24 citations
Semantic Scholar
Synthesis and biological evaluation of benzo[4,5]imidazo[1,2-c]pyrimidine and benzo[4,5]imidazo[1,2-a]pyrazine derivatives as anaplastic lymphoma kinase inhibitors.
S. Tardy, A. Orsato, L. Mologni, W. Bisson +5 more
2014Bioorganic & Medicinal Chemistry23 citations Open access
Semantic Scholar
RET kinase inhibitors: a review of recent patents (2012–2015)
L. Mologni, C. Gambacorti-Passerini, P. Goekjian, L. Scapozza
2017Expert Opinion on Therapeutic Patents22 citations
Semantic Scholar
Purine metabolite and energy charge analysis of Trypanosoma brucei cells in different growth phases using an optimized ion-pair RP-HPLC/UV for the quantification of adenine and guanine pools.
P. Graven, M. Tambalo, L. Scapozza, R. Perozzo
2014Experimental parasitology21 citations
Semantic Scholar
RNA interference screening identifies a novel role for PCTK1/CDK16 in medulloblastoma with c-Myc amplification
Paulina C'wiek, Z. Leni, Fabiana Salm, V. Dimitrova +8 more
2014OncoTarget21 citations Open access
Semantic Scholar
Challenges and Opportunities in the Oral Delivery of Recombinant Biologics
Solène Masloh, M. Culot, F. Gosselet, A. Chevrel +2 more
2023Pharmaceutics19 citations Open access
Semantic Scholar
Chemoenzymatic Synthesis of Original Stilbene Dimers Possessing Wnt Inhibition Activity in Triple-Negative Breast Cancer Cells Using the Enzymatic Secretome of Botrytis cinerea Pers.
R. Huber, A. Koval, L. Marcourt, M. Héritier +7 more
2022Frontiers in Chemistry19 citations Open access
Semantic Scholar
Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1
Meropi Bagka, Hye-Ji Choi, M. Héritier, Hanna Schwaemmle +5 more
2022bioRxiv19 citations Open access
Semantic Scholar
Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6
A. Balaphas, Jérémy Meyer, R. Perozzo, Magali Zeisser-Labouèbe +6 more
2020Cells19 citations Open access
Semantic Scholar
Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model
Hajer Ouertatani-Sakouhi, Sébastien Kicka, Gianpaolo Chiriano, Christopher F. Harrison +4 more
2017PLoS ONE19 citations Open access
Semantic Scholar
Exploring the Ubiquitin-Proteasome System (UPS) through PROTAC Technology.
Carlotta Cecchini, S. Tardy, V. Ceserani, Jean-Philippe P. Theurillat +1 more
2020Chimia (Basel)17 citations Open access
Semantic Scholar
Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteases
B. Mukherjee, F. Tessaro, J. Vahokoski, I. Kursula +3 more
2018EMBO Journal17 citations Open access
Semantic Scholar
Synthesis of 3-azabicyclo[3.2.2]nonanes and their antiprotozoal activities.
W. Seebacher, V. Wolkinger, J. Faist, M. Kaiser +10 more
2015Bioorganic & Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation
O. Preynat-Seauve, E. Nguyen, Y. Westermaier, M. Héritier +6 more
2021Frontiers in Pharmacology16 citations Open access
Semantic Scholar
TTAS a new stilbene derivative that induces apoptosis in Leishmania infantum.
M. Tolomeo, M. Roberti, L. Scapozza, C. Tarantelli +5 more
2013Experimental parasitology16 citations Open access
Semantic Scholar
Repurposing the Selective Oestrogen Receptor Modulator Tamoxifen for the Treatment of Duchenne Muscular Dystrophy.
E. Gayi, L. Neff, H. M. Ismail, U. Ruegg +2 more
2018Chimia (Basel)15 citations Open access
Semantic Scholar
Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila.
Christopher F. Harrison, Gianpaolo Chiriano, Ivo Finsel, C. Manske +10 more
2015ACS Infectious Diseases15 citations Open access
Semantic Scholar
Glomerular Macrophages in Human Auto- and Allo-Immune Nephritis
S. Moll, A. Angeletti, L. Scapozza, A. Cavalli +2 more
2021Cells14 citations Open access
Semantic Scholar
Identification of Anti-Mycobacterium and Anti-Legionella Compounds With Potential Distinctive Structural Scaffolds From an HD-PBL Using Phenotypic Screens in Amoebae Host Models
N. Hanna, Sébastien Kicka, Gianpaolo Chiriano, Christopher F. Harrison +9 more
2020Frontiers in Microbiology13 citations Open access
Semantic Scholar
The potential and benefits of repurposing existing drugs to treat rare muscular dystrophies
H. M. Ismail, O. Dorchies, L. Scapozza
201812 citations
Semantic Scholar
A novel oxido-viscosifying Hyaluronic Acid-antioxidant conjugate for osteoarthritis therapy: biocompatibility assessments.
S. Kaderli, C. Boulocher, E. Pillet, Dorothée Watrelot-Virieux +5 more
2015European journal of pharmaceutics and biopharmaceutics12 citations
Semantic Scholar
Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33
Florian Rouaud, F. Tessaro, Laura Aimaretti, L. Scapozza +1 more
2020Journal of Biological Chemistry11 citations Open access
Semantic Scholar
Adrenergic antagonists restrict replication of Legionella.
Christopher F. Harrison, Sébastien Kicka, Agata Kranjc, Ivo Finsel +5 more
2015Microbiology11 citations Open access
Semantic Scholar

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Gianpaolo Chiriano×10
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Gianpaolo Chiriano — researcher profile on SciRah
R. Perozzo×8
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R. Perozzo — researcher profile on SciRah
Sébastien Kicka×7
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Sébastien Kicka — researcher profile on SciRah
Thierry Soldati×7
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S. Tardy — researcher profile on SciRah

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