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Kyoko Ochiai · SciRah

Researcher profile · Semantic Scholar

Kyoko Ochiai

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Kyoko Ochiai — researcher profile on SciRah

h-index: 20
Works: 33
Citations: 2,597

Most-cited papers

Article Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of Irf4
Kyoko Ochiai, M. Maienschein-Cline, G. Simonetti, Jian-Jun Chen +7 more
436 citations
Semantic Scholar
S-Adenosylmethionine Synthesis Is Regulated by Selective N6-Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC1.
Hiroki Shima, Mitsuyo Matsumoto, Yuma Ishigami, Masayuki Ebina +6 more
2017Cell Reports327 citations Open access
Semantic Scholar
Orchestrating B cell lymphopoiesis through interplay of IL-7 receptor and pre-B cell receptor signalling
M. Clark, M. Mandal, Kyoko Ochiai, Harinder Singh
2013Nature reviews. Immunology318 citations Open access
Semantic Scholar
Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch
A. Muto, Kyoko Ochiai, Y. Kimura, Ari Itoh-Nakadai +4 more
2010EMBO Journal213 citations Open access
Semantic Scholar
A self-reinforcing regulatory network triggered by limiting interleukin-7 activates pre-BCR signaling and differentiation
Kyoko Ochiai, M. Maienschein-Cline, M. Mandal, Joseph R. Triggs +5 more
2012Nature Immunology163 citations Open access
Semantic Scholar
Plasmacytic Transcription Factor Blimp-1 Is Repressed by Bach2 in B Cells*
Kyoko Ochiai, Y. Katoh, T. Ikura, Yutaka Hoshikawa +5 more
2006Journal of Biological Chemistry162 citations Open access
Semantic Scholar
The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program
Ari Itoh-Nakadai, Reina Hikota, A. Muto, K. Kometani +12 more
2014Nature Immunology135 citations
Semantic Scholar
Ras orchestrates cell cycle exit and light chain recombination during early B cell development
M. Mandal, Sarah E. Powers, Kyoko Ochiai, Katia Georgopoulos +3 more
2009Nature Immunology117 citations Open access
Semantic Scholar
Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6.
Kyoko Ochiai, A. Muto, Hiromu Tanaka, Shinichirou Takahashi +1 more
2008International Immunology116 citations Open access
Semantic Scholar
Orchestration of plasma cell differentiation by Bach2 and its gene regulatory network
K. Igarashi, Kyoko Ochiai, Ari Itoh-Nakadai, A. Muto
2014Immunological Reviews84 citations
Semantic Scholar
Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3*
Hiromu Tanaka, A. Muto, Hiroki Shima, Y. Katoh +11 more
2016Journal of Biological Chemistry74 citations Open access
Semantic Scholar
Identification of six major outer membrane proteins from Actinobacillus actinomycetemcomitans.
H. Komatsuzawa, Ryuji Asakawa, T. Kawai, Kyoko Ochiai +5 more
2002Gene64 citations
Semantic Scholar
A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors.
Ari Itoh-Nakadai, Mitsuyo Matsumoto, Hiroki Kato, Junichi Sasaki +9 more
2017Cell Reports57 citations Open access
Semantic Scholar
Architecture and dynamics of the transcription factor network that regulates B-to-plasma cell differentiation.
K. Igarashi, Kyoko Ochiai, A. Muto
2007Journal of Biochemistry (Tokyo)56 citations
Semantic Scholar
Transcription Factor IRF8 Governs Enhancer Landscape Dynamics in Mononuclear Phagocyte Progenitors.
D. Kurotaki, J. Nakabayashi, A. Nishiyama, Haruka Sasaki +7 more
2018Cell Reports52 citations Open access
Semantic Scholar
Zinc finger-IRF composite elements bound by Ikaros/IRF4 complexes function as gene repression in plasma cell.
Kyoko Ochiai, Haruka Kondo, Yasunobu Okamura, Hiroki Shima +8 more
2018Blood Advances45 citations Open access
Semantic Scholar
The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization*
Ryo Ando, Hiroki Shima, Toru Tamahara, Yoshihiro Sato +11 more
2015Journal of Biological Chemistry42 citations Open access
Semantic Scholar
The mTOR-Bach2 Cascade Controls Cell Cycle and Class Switch Recombination during B Cell Differentiation
Toru Tamahara, Kyoko Ochiai, A. Muto, Y. Kato +4 more
2017Molecular and Cellular Biology33 citations Open access
Semantic Scholar
Chromatin Protein PC4 Orchestrates B Cell Differentiation by Collaborating with IKAROS and IRF4.
Kyoko Ochiai, Mari Yamaoka, Amrutha Swaminathan, Hiroki Shima +13 more
2020Cell Reports24 citations Open access
Semantic Scholar
Accelerated plasma-cell differentiation in Bach2-deficient mouse B cells is caused by altered IRF4 functions
Kyoko Ochiai, Hiroki Shima, T. Tamahara, Naomi F. Sugie +4 more
2024EMBO Journal21 citations Open access
Semantic Scholar
Bach1 promotes muscle regeneration through repressing Smad-mediated inhibition of myoblast differentiation
Katsushi Suzuki, Mitsuyo Matsumoto, Y. Katoh, Liang Liu +6 more
2020PLoS ONE20 citations Open access
Semantic Scholar
BACH1 Expression Is Promoted by Tank Binding Kinase 1 (TBK1) in Pancreatic Cancer Cells to Increase Iron and Reduce the Expression of E-Cadherin
Liang Liu, Mitsuyo Matsumoto, M. Matsui-Watanabe, Kyoko Ochiai +6 more
2022Antioxidants12 citations Open access
Semantic Scholar
Exploring novel functions of BACH2 in the acquisition of antigen-specific antibodies.
Kyoko Ochiai, K. Igarashi
2022International Immunology10 citations Open access
Semantic Scholar
TANK Binding Kinase 1 Promotes BACH1 Degradation through Both Phosphorylation-Dependent and -Independent Mechanisms without Relying on Heme and FBXO22
Liang Liu, Mitsuyo Matsumoto, M. Watanabe-Matsui, Tadashi Nakagawa +12 more
2024bioRxiv7 citations Open access
Semantic Scholar
Heme regulates protein interactions and phosphorylation of BACH2 intrinsically disordered region in humoral response
M. Watanabe-Matsui, Shun Kadoya, Kei Segawa, Hiroki Shima +13 more
2024iScience5 citations Open access
Semantic Scholar
Protocol for in vitro BCR-mediated plasma cell differentiation and purification of chromatin-associated proteins
Kyoko Ochiai, Hiroki Shima, T. Ikura, M. Franke +3 more
2021STAR Protocols4 citations Open access
Semantic Scholar
Feedback loops in B-cell chromatin regulation as a therapeutic target for modulating antibody production and malignancies: insights from BACH2.
Kyoko Ochiai, Kazuhiko Igarashi
2025Experimental Hematology2 citations Open access
Semantic Scholar
Absolute quantification of BACH1 and BACH2 transcription factors in B and plasma cells reveals their dynamic changes and unique roles.
Takeshi Kurasawa, A. Muto, Mitsuyo Matsumoto, Kyoko Ochiai +2 more
2024Journal of Biochemistry (Tokyo)1 citations
Semantic Scholar
Positive coactivator PC4 shows dynamic nucleolar distribution required for rDNA transcription and protein synthesis
Stephanie Kaypee, Kyoko Ochiai, Hiroki Shima, Mitsuyo Matsumoto +4 more
2025Cell Communication and Signaling0 citations Open access
Semantic Scholar
Identification of histone H3K36 methyltransferase Whsc1 protein complex
Julie Sugio, M. Kashio, Ryo Maeda, Kyoko Ochiai +2 more
20160 citations
Semantic Scholar
A self-reinforcing regulatory network triggered by limiting interleukin-7 activates pre-BCR signaling and differentiation
Kyoko Ochiai, M. Maienschein-Cline, M. Mandal, Joseph R. Triggs +6 more
20140 citations
Semantic Scholar
Plasma cell differentiation (WS-050) Chairpersons: Takeshi Tokuhisa, Stephen Nutt
E. Mohr, A. Cunningham, K. Toellner, R. Manz +46 more
20100 citations
Semantic Scholar
B cell development (WS-030) Chairpersons: Daisuke Kitamura, David Gray
Kyoko Ochiai, Harinder Singh, T. Vu, Alister P. W. Funnell +44 more
20100 citations Open access
Semantic Scholar

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K. Igarashi×20
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K. Igarashi — researcher profile on SciRah
A. Muto×15
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Hiroki Shima×10
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Mitsuyo Matsumoto×10
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Ari Itoh-Nakadai×4

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M. Watanabe-Matsui×4

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M. Watanabe-Matsui — researcher profile on SciRah

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R. Funayama — researcher profile on SciRah