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O. Witte · SciRah

Researcher profile · Semantic Scholar

O. Witte

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O. Witte — researcher profile on SciRah

h-index: 106
Works: 398
Citations: 39K

Most-cited papers

Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study.
R. Aggarwal, Jiao-Ti Huang, J. Alumkal, Li Zhang +27 more
2018Journal of Clinical Oncology686 citations Open access
Semantic Scholar
Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.
D. Quigley, H. Dang, Shuang G. Zhao, P. Lloyd +59 more
2018Cell658 citations Open access
Semantic Scholar
N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells
John K. Lee, J. Phillips, Bryan A. Smith, J. Park +12 more
2016Cancer Cell373 citations Open access
Semantic Scholar
Reprogramming normal human epithelial tissues to a common, lethal neuroendocrine cancer lineage
J. Park, John K. Lee, K. Sheu, Liang Wang +10 more
2018Science300 citations Open access
Semantic Scholar
An effective immuno-PET imaging method to monitor CD8-dependent responses to immunotherapy
Richard Tavaré, Helena Escuin-Ordinas, Stephen Mok, Melissa N. Mccracken +5 more
2015Cancer Research270 citations Open access
Semantic Scholar
Adoptive transfer of MART-1 T cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma
T. Chodon, B. Comin-Anduix, B. Chmielowski, R. Koya +30 more
2014Clinical Cancer Research237 citations Open access
Semantic Scholar
DNA methylation landscapes in advanced prostate cancer
Shuang G. Zhao, William S. Chen, Hao-Long Li, A. Foye +65 more
2020Nature Genetics228 citations Open access
Semantic Scholar
Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer
J. Drake, Evan O. Paull, N. Graham, John K. Lee +16 more
2016Cell219 citations Open access
Semantic Scholar
A basal stem cell signature identifies aggressive prostate cancer phenotypes
Bryan A. Smith, A. Sokolov, V. Uzunangelov, R. Baertsch +6 more
2015Proceedings of the National Academy of Sciences of the United States of America203 citations Open access
Semantic Scholar
Engineered antibody fragments for immuno-PET imaging of endogenous CD8+ T cells in vivo
Richard Tavaré, Melissa N. Mccracken, K. Zettlitz, Scott M. Knowles +4 more
2014Proceedings of the National Academy of Sciences of the United States of America165 citations Open access
Semantic Scholar
Pan-cancer convergence to a small cell neuroendocrine phenotype that shares susceptibilities with hematological malignancies
N. Balanis, K. Sheu, Favour N Esedebe, Saahil Patel +7 more
2019Cancer Cell161 citations Open access
Semantic Scholar
T cell antigen discovery via trogocytosis
Guideng Li, Michael T. Bethune, Stephanie W. Y. Wong, Alok V. Joglekar +12 more
2019Nature Methods147 citations Open access
Semantic Scholar
Systemic surfaceome profiling identifies target antigens for immune-based therapy in subtypes of advanced prostate cancer
John K. Lee, Nathanael J. Bangayan, Timothy Chai, Bryan A. Smith +10 more
2018Proceedings of the National Academy of Sciences of the United States of America128 citations Open access
Semantic Scholar
Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance
J. Alumkal, Duan-Chen Sun, Eric Lu, T. Beer +27 more
2020Proceedings of the National Academy of Sciences of the United States of America127 citations Open access
Semantic Scholar
Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets
J. Drake, N. Graham, John K. Lee, Tanya Stoyanova +7 more
2013Proceedings of the National Academy of Sciences of the United States of America127 citations Open access
Semantic Scholar
Prostate epithelial cell of origin determines cancer differentiation state in an organoid transformation assay
J. Park, John K. Lee, J. Phillips, Patrick Huang +3 more
2016Proceedings of the National Academy of Sciences of the United States of America122 citations Open access
Semantic Scholar
ImmunoPET of murine T cell reconstitution post-adoptive stem cell transplant using anti-CD4 and anti-CD8 cys-diabodies
Richard Tavaré, Melissa N. Mccracken, K. Zettlitz, Felix B Salazar +3 more
2015Journal of Nuclear Medicine110 citations Open access
Semantic Scholar
FOXA2 is a Sensitive and Specific marker for Small Cell Neuroendocrine Carcinoma of the Prostate
J. Park, John K. Lee, O. Witte, Jiao-Ti Huang
2017Modern Pathology108 citations Open access
Semantic Scholar
Targeting cellular heterogeneity with CXCR2 blockade for the treatment of therapy-resistant prostate cancer
Yanjing Li, Yi-Ping He, William Butler, Ling-Fan Xu +29 more
2019Science Translational Medicine107 citations Open access
Semantic Scholar
Low CD38 Identifies Progenitor-like Inflammation-Associated Luminal Cells that Can Initiate Human Prostate Cancer and Predict Poor Outcome
Xian Liu, T. Grogan, H. Hieronymus, T. Hashimoto +15 more
2016Cell Reports102 citations Open access
Semantic Scholar
MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer
N. Nickols, R. Nazarian, Shuang G. Zhao, Victor M. Tan +27 more
2019Prostate Cancer and Prostatic Diseases88 citations Open access
Semantic Scholar
Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer
Yan-Ni Zhu, Drake J. Smith, Yang Zhou, Yan-Ruide Li +40 more
2019Cell Stem Cell87 citations Open access
Semantic Scholar
Clinical Targeting of Mutated and Wild-Type Protein Tyrosine Kinases in Cancer
J. Drake, John K. Lee, O. Witte
2014Molecular and Cellular Biology83 citations Open access
Semantic Scholar
Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood
Songming Peng, J. Zaretsky, Alphonsus H. C. Ng, W. Chour +19 more
2019Cell Reports81 citations Open access
Semantic Scholar
[18F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity
Woosuk Kim, Thuc M. Le, Liu H. Wei, Soumya Poddar +24 more
2016Proceedings of the National Academy of Sciences of the United States of America80 citations Open access
Semantic Scholar
Isolation and characterization of NY-ESO-1–specific T cell receptors restricted on various MHC molecules
Michael T. Bethune, Xiao-hua Li, Jia-Ji Yu, J. McLaughlin +14 more
2018Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
Semantic Scholar
Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers
J. Phillips, Yang Pan, Brandon L. Tsai, Zhijie Xie +11 more
2020Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
The 5-Hydroxymethylcytosine Landscape of Prostate Cancer
Martin Sjöström, S. Zhao, S. Levy, Meng Zhang +60 more
2022Cancer Research55 citations Open access
Semantic Scholar
The Genomic and Epigenomic Landscape of Double-Negative Metastatic Prostate Cancer
Arian Lundberg, Meng Zhang, R. Aggarwal, Hao-Long Li +24 more
2023Cancer Research54 citations Open access
Semantic Scholar
Functional screen identifies kinases driving prostate cancer visceral and bone metastasis
Claire M. Faltermeier, J. Drake, P. M. Clark, Bryan A. Smith +7 more
2015Proceedings of the National Academy of Sciences of the United States of America52 citations Open access
Semantic Scholar
Interleukin-6 and oncostatin-M synergize with the PI3K/AKT pathway to promote aggressive prostate malignancy in mouse and human tissues
Daniel A. Smith, Atsushi Kiba, Y. Zong, O. Witte
2013Molecular Cancer Research51 citations Open access
Semantic Scholar
IRIS: Discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing
Yang Pan, J. Phillips, Beatrice Zhang, Miyako Noguchi +22 more
2023Proceedings of the National Academy of Sciences of the United States of America49 citations Open access
Semantic Scholar
RNA Dysregulation: An Expanding Source of Cancer Immunotherapy Targets
Yang Pan, Kathryn E. Kadash-Edmondson, Robert Y. Wang, J. Phillips +5 more
2021TIPS - Trends in Pharmacological Sciences48 citations Open access
Semantic Scholar
Long-term in vivo monitoring of mouse and human hematopoietic stem cell engraftment with a human positron emission tomography reporter gene
Melissa N. Mccracken, Eric H. Gschweng, Evan Nair-Gill, J. McLaughlin +6 more
2013Proceedings of the National Academy of Sciences of the United States of America45 citations Open access
Semantic Scholar
Targeting RET Kinase in Neuroendocrine Prostate Cancer
Halena R. VanDeusen, Johnny R. Ramroop, K. Morel, S. Y. Bae +18 more
2020Molecular Cancer Research44 citations Open access
Semantic Scholar
Genetic engineering of hematopoietic stem cells to generate invariant natural killer T cells
Drake J. Smith, Siyuan Liu, Sunjong Ji, Bo Li +4 more
2015Proceedings of the National Academy of Sciences of the United States of America43 citations Open access
Semantic Scholar
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre–B ALL
H. Schjerven, Etapong F Ayongaba, Ali Aghajanirefah, J. McLaughlin +11 more
2017Journal of Experimental Medicine38 citations Open access
Semantic Scholar
HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice
Eric H. Gschweng, Melissa N. Mccracken, Michael L. Kaufman, Michelle W. L. Ho +8 more
2014Cancer Research37 citations Open access
Semantic Scholar
The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells
Xin-Yuan Chen, H. Yang, Ben Zhang, J. Phillips +5 more
2022bioRxiv35 citations Open access
Semantic Scholar
A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes
Liang Wang, Bryan A. Smith, N. Balanis, Brandon L. Tsai +14 more
2019Proceedings of the National Academy of Sciences of the United States of America34 citations Open access
Semantic Scholar
Noninvasive detection of tumor-infiltrating T cells by PET reporter imaging.
Melissa N. Mccracken, D. Vatakis, D. Dixit, J. McLaughlin +2 more
2015Journal of Clinical Investigation34 citations Open access
Semantic Scholar
HLA-A∗02:01 restricted T cell receptors against the highly conserved SARS-CoV-2 polymerase cross-react with human coronaviruses
Pavlo A. Nesterenko, J. McLaughlin, Brandon L. Tsai, Giselle Burton Sojo +19 more
2021Cell Reports33 citations Open access
Semantic Scholar
Deoxycytidine Kinase Augments ATM-Mediated DNA Repair and Contributes to Radiation Resistance
Y. Bunimovich, Evan Nair-Gill, Mireille Riedinger, Melissa N. Mccracken +4 more
2014PLoS ONE31 citations Open access
Semantic Scholar
Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver
P. M. Clark, G. Flores, N. M. Evdokimov, Melissa N. Mccracken +8 more
2014Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
18F-FAC PET Visualizes Brain-Infiltrating Leukocytes in a Mouse Model of Multiple Sclerosis
Bao Chen, C. Ghezzi, Brendon Villegas, A. Quon +3 more
2019Journal of Nuclear Medicine19 citations Open access
Semantic Scholar
Lift NIH restrictions on chimera research.
Arun Sharma, V. Sebastiano, C. Scott, David Magnus +7 more
2015Science19 citations Open access
Semantic Scholar
Droplet-based mRNA sequencing of fixed and permeabilized cells by CLInt-seq allows for antigen-specific TCR cloning
Pavlo A. Nesterenko, J. McLaughlin, D. Cheng, Nathanael J. Bangayan +7 more
2021Proceedings of the National Academy of Sciences of the United States of America15 citations Open access
Semantic Scholar
Clinical and genomic characterization of metastatic small cell/neuroendocrine prostate cancer (SCNC) and intermediate atypical prostate cancer (IAC): Results from the SU2C/PCF/AACRWest Coast Prostate Cancer Dream Team (WCDT).
E. Small, R. Aggarwal, Jiao-Ti Huang, A. Sokolov +16 more
201615 citations
Semantic Scholar
Targeting Adaptive Pathways in Metastatic Treatment-Resistant Prostate Cancer: Update on the Stand Up 2 Cancer/Prostate Cancer Foundation-Supported West Coast Prostate Cancer Dream Team.
R. Aggarwal, T. Beer, M. Gleave, Joshua M. Stuart +8 more
2016European Urology Focus15 citations
Semantic Scholar
IRIS: Big data-informed discovery of cancer immunotherapy targets arising from pre-mRNA alternative splicing
Yang Pan, Alexander H. Lee, H. Yang, Yuanyuan Wang +9 more
2019bioRxiv14 citations Open access
Semantic Scholar

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