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H. Siddle · SciRah

Researcher profile · Semantic Scholar

H. Siddle

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H. Siddle — researcher profile on SciRah

h-index: 22
Works: 43
Citations: 2,716

Most-cited papers

An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
M. Burr, C. Sparbier, K. Chan, Yih-Chih Chan +24 more
2019Cancer Cell596 citations Open access
Semantic Scholar
Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial
H. Siddle, A. Kreiss, M. Eldridge, E. Noonan +4 more
2007Proceedings of the National Academy of Sciences of the United States of America289 citations Open access
Semantic Scholar
Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex
K. Belov, J. Deakin, A. Papenfuss, M. Baker +14 more
2006PLoS Biology221 citations Open access
Semantic Scholar
Reversible epigenetic down-regulation of MHC molecules by devil facial tumour disease illustrates immune escape by a contagious cancer
H. Siddle, A. Kreiss, Cesar Tovar, Chun-Kit Yuen +9 more
2013Proceedings of the National Academy of Sciences of the United States of America215 citations Open access
Semantic Scholar
MHC gene copy number variation in Tasmanian devils: implications for the spread of a contagious cancer
H. Siddle, J. Marzec, Yuanyuan Cheng, Menna E. Jones +1 more
2010Proceedings of the Royal Society of London. Biological Sciences152 citations Open access
Semantic Scholar
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
M. Renfree, A. Papenfuss, J. Deakin, James Lindsay +99 more
2011Genome Biology132 citations Open access
Semantic Scholar
The Origins and Vulnerabilities of Two Transmissible Cancers in Tasmanian Devils
Maximilian R. Stammnitz, Tim H. H. Coorens, Kevin Gori, D. Hayes +22 more
2018Cancer Cell100 citations Open access
Semantic Scholar
Genome sequence of an Australian kangaroo, Macropus eugenii, provides insight into the evolution of mammalian reproduction and development
M. Renfree, A. Papenfuss, J. Deakin, James Lindsay +100 more
2011Genome Biology100 citations Open access
Semantic Scholar
Demonstration of immune responses against devil facial tumour disease in wild Tasmanian devils
Ruth J. Pye, R. Hamede, H. Siddle, A. Caldwell +6 more
2016Biology Letters93 citations Open access
Semantic Scholar
The Immune Response of the Tasmanian Devil (Sarcophilus harrisii) and Devil Facial Tumour Disease
Gregory M. Woods, A. Kreiss, K. Belov, H. Siddle +2 more
2007EcoHealth80 citations Open access
Semantic Scholar
Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils
Cesar Tovar, Ruth J. Pye, A. Kreiss, Yuanyuan Cheng +15 more
2017Scientific Reports69 citations Open access
Semantic Scholar
Antigen-presenting genes and genomic copy number variations in the Tasmanian devil MHC
Yuanyuan Cheng, Andrew B. Stuart, K. Morris, Robyn L. Taylor +5 more
2012BMC Genomics62 citations Open access
Semantic Scholar
Characterization of major histocompatibility complex class I and class II genes from the Tasmanian devil (Sarcophilus harrisii)
H. Siddle, Claire E. Sanderson, K. Belov
2007Immunogenetics60 citations
Semantic Scholar
MHC-linked and un-linked class I genes in the wallaby
H. Siddle, J. E. Deakin, P. Coggill, Elizabeth Hart +5 more
2009BMC Genomics55 citations Open access
Semantic Scholar
The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer
A. Caldwell, Rachel Coleby, Cesar Tovar, Maximilian R. Stammnitz +10 more
2018eLife53 citations Open access
Semantic Scholar
Immunology of naturally transmissible tumours
H. Siddle, J. Kaufman
2014Immunology53 citations Open access
Semantic Scholar
The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease
Lindsay Kosack, B. Wingelhofer, A. Popa, A. Orlova +24 more
2018bioRxiv51 citations Open access
Semantic Scholar
The ecology and evolution of wildlife cancers: Applications for management and conservation
R. Hamede, Rachel S. Owen, H. Siddle, Sarah Peck +6 more
2020Evolutionary Applications41 citations Open access
Semantic Scholar
Tracing the rise of malignant cell lines: Distribution, epidemiology and evolutionary interactions of two transmissible cancers in Tasmanian devils
Samantha E. James, Geordie Jennings, Y. Kwon, Maximilian R. Stammnitz +17 more
2019Evolutionary Applications41 citations Open access
Semantic Scholar
A tale of two tumours: Comparison of the immune escape strategies of contagious cancers
H. Siddle, J. Kaufman
2013Molecular Immunology41 citations Open access
Semantic Scholar
Class I genes have split from the MHC in the tammar wallaby
J. E. Deakin, H. Siddle, J. Cross, Katherine Belov +1 more
2007Cytogenetic and Genome Research38 citations
Semantic Scholar
The tammar wallaby major histocompatibility complex shows evidence of past genomic instability
H. Siddle, J. Deakin, P. Coggill, Laurens G Whilming +4 more
2011BMC Genomics37 citations Open access
Semantic Scholar
Darwin, the devil, and the management of transmissible cancers
R. Hamede, T. Madsen, H. McCallum, A. Storfer +7 more
2020Conservation Biology18 citations Open access
Semantic Scholar
High levels of genetic variation at MHC class II DBB loci in the tammar wallaby (Macropus eugenii)
Yuanyuan Cheng, H. Siddle, S. Beck, M. Eldridge +1 more
2009Immunogenetics18 citations
Semantic Scholar
Isolation of major histocompatibility complex Class I genes from the tammar wallaby (Macropus eugenii)
H. Siddle, J. Deakin, M. Baker, Robert D. Miller +1 more
2006Immunogenetics15 citations
Semantic Scholar
The role of MHC genes in contagious cancer: the story of Tasmanian devils
A. Caldwell, H. Siddle
2017Immunogenetics14 citations Open access
Semantic Scholar
How the devil facial tumor disease escapes host immune responses
H. Siddle, J. Kaufman
2013Oncoimmunology14 citations Open access
Semantic Scholar
Devil Facial Tumours: Towards a Vaccine
Rachel S. Owen, H. Siddle
2019Immunological Investigations12 citations Open access
Semantic Scholar
Transmissible Cancer Evolution: The Under-Estimated Role of Environmental Factors in the “Perfect Storm” Theory
S. Tissot, Anne-Lise Gérard, Justine Boutry, A. Dujon +8 more
2022Pathogens8 citations Open access
Semantic Scholar
Isolation and characterization of 10 MHC Class I‐associated microsatellite loci in tammar wallaby (Macropus eugenii)
Yuanyuan Cheng, M. Wakefield, H. Siddle, P. Coggill +4 more
2009Molecular Ecology Resources8 citations
Semantic Scholar
Class II transactivator induces expression of MHC-I and MHC-II in transmissible Tasmanian devil facial tumours
Chrissie E. B. Ong, Yuanyuan Cheng, H. Siddle, A. Lyons +2 more
2022Open Biology7 citations Open access
Semantic Scholar
The differentiation state of the Schwann cell progenitor drives phenotypic variation between two contagious cancers
Rachel S. Owen, Sri H. Ramarathinam, A. Bailey, A. Gastaldello +4 more
2021PLoS Pathogens6 citations Open access
Semantic Scholar
CIITA induces expression of MHC-I and MHC-II in transmissible cancers
Chrissie E. B. Ong, Yuanyuan Cheng, H. Siddle, A. Lyons +2 more
2021bioRxiv4 citations Open access
Semantic Scholar
The immunopeptidomes of two transmissible cancers and their host have a common, dominant peptide motif
A. Gastaldello, Sri H. Ramarathinam, A. Bailey, Rachel S. Owen +6 more
2021Immunology4 citations Open access
Semantic Scholar
The Marsupial Major Histocompatibility Complex
Yuanyuan Cheng, H. Siddle, K. Belov
20104 citations
Semantic Scholar
Immune escape strategies of a contagious cancer, devil facial tumour disease
H. Siddle, A. Kreiss, Cesar Tovab, Yuanyuan Cheng +6 more
20123 citations
Semantic Scholar
Genetic architecture of the macropodid immune system
H. Siddle, Claire E. Sanderson, J. Deakin, K. Belov
20103 citations
Semantic Scholar
Antigen-presenting genes and genomic copy number variations in the Tasmanian devil MHC
Yuanyuan Cheng, Andrew B. Stuart, K. Morris, Robyn L. Taylor +5 more
2012BMC Genomics1 citations Open access
Semantic Scholar
Expression of the Nonclassical MHC Class I, Saha-UD in the Transmissible Cancer Devil Facial Tumour Disease (DFTD)
K. Hussey, A. Caldwell, A. Kreiss, K. Skjødt +5 more
2022Pathogens0 citations Open access
Semantic Scholar
Regulation of MHC-I and MHC-II by CIITA in transmissible cancers
Chrissie E. B. Ong, Yuanyuan Cheng, H. Siddle, A. Lyons +2 more
20210 citations Open access
Semantic Scholar
Author response: The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer
A. Caldwell, Rachel Coleby, Cesar Tovar, Maximilian R. Stammnitz +10 more
20180 citations Open access
Semantic Scholar
Syddansk Universitet Regression of devil facial tumour disease following immunotherapy in immunised
Cesar Tovar, Ruth J. Pye, A. Kreiss, Yuanyuan Cheng +15 more
20170 citations
Semantic Scholar
Reconstructing an Ancestral MammalianImmune Supercomplex from a Marsupial MajorHistocompatibility Complex
K. Belov, H. Siddle, M. Baker, P. Benos +14 more
20060 citations
Semantic Scholar

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