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C. Toulas · SciRah

Researcher profile · Semantic Scholar

C. Toulas

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C. Toulas — researcher profile on SciRah

h-index: 32
Works: 95
Citations: 2,779

Most-cited papers

Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response
J. Sesen, P. Dahan, S. Scotland, E. Saland +8 more
2015PLoS ONE208 citations Open access
Semantic Scholar
Alphavbeta3/alphavbeta5 integrins-FAK-RhoB: a novel pathway for hypoxia regulation in glioblastoma.
Nicolas Skuli, S. Monferran, C. Delmas, G. Favre +3 more
2009Cancer Research131 citations
Semantic Scholar
Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids
Giulia Pinto, Inés Saénz-de-Santa-María, P. Chastagner, Émeline Perthame +5 more
2020bioRxiv130 citations Open access
Semantic Scholar
αvβ3 and αvβ5 integrins control glioma cell response to ionising radiation through ILK and RhoB
S. Monferran, Nicolas Skuli, C. Delmas, G. Favre +3 more
2008International Journal of Cancer121 citations
Semantic Scholar
Interest of integrins targeting in glioblastoma according to tumor heterogeneity and cancer stem cell paradigm: an update
Laure Malric, S. Monferran, J. Gilhodes, S. Boyrie +8 more
2017OncoTarget99 citations Open access
Semantic Scholar
The m6A RNA Demethylase ALKBH5 Promotes Radioresistance and Invasion Capability of Glioma Stem Cells
A. Kowalski‐Chauvel, Marie Geraldine Lacore, F. Arnauduc, C. Delmas +3 more
2020Cancers95 citations Open access
Semantic Scholar
Farnesyltransferase inhibitor, R115777, reverses the resistance of human glioma cell lines to ionizing radiation
C. Delmas, C. Héliez, E. Cohen-Jonathan, D. End +3 more
2002International Journal of Cancer93 citations Open access
Semantic Scholar
Radioresistance induced by the high molecular forms of the basic fibroblast growth factor is associated with an increased G2 delay and a hyperphosphorylation of p34CDC2 in HeLa cells.
E. Cohen-Jonathan, C. Toulas, Sylvia Monteil, B. Couderc +5 more
1997Cancer Research84 citations
Semantic Scholar
Activation of RhoB by hypoxia controls hypoxia-inducible factor-1alpha stabilization through glycogen synthase kinase-3 in U87 glioblastoma cells.
Nicolas Skuli, S. Monferran, C. Delmas, I. Lajoie-Mazenc +3 more
2006Cancer Research79 citations Open access
Semantic Scholar
The farnesyltransferase inhibitor R115777 reduces hypoxia and matrix metalloproteinase 2 expression in human glioma xenograft.
C. Delmas, D. End, P. Rochaix, G. Favre +2 more
2003Clinical Cancer Research75 citations
Semantic Scholar
RhoB controls the 24 kDa FGF-2-induced radioresistance in HeLa cells by preventing post-mitotic cell death
I. Ader, C. Toulas, F. Dalenc, C. Delmas +3 more
2002Oncogene70 citations
Semantic Scholar
The contribution of germline rearrangements to the spectrum of BRCA2 mutations
Federica Casilli, Isabelle Tournier, O. Sinilnikova, F. Coulet +31 more
2006Journal of Medical Genetics65 citations Open access
Semantic Scholar
The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit
I. Ader, C. Muller, J. Bonnet, G. Favre +3 more
2002Oncogene65 citations
Semantic Scholar
Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts
I. Ader, C. Delmas, J. Bonnet, P. Rochaix +3 more
2003Oncogene63 citations Open access
Semantic Scholar
An unusual phenotype occurs in 15% of mismatch repair-deficient tumors and is associated with non-colorectal cancers and genetic syndromes
M. Jaffrelot, N. Farès, Anne-Cécile Brunac, A. Laurenty +14 more
2021Modern Pathology60 citations Open access
Semantic Scholar
BRCA Share: A Collection of Clinical BRCA Gene Variants
C. Béroud, Stanley I. Letovsky, Corey D. Braastad, S. Caputo +33 more
2016Human Mutation57 citations Open access
Semantic Scholar
αvβ3 Integrin and Fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of Tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma.
A. Ducassou, E. Uro-Coste, P. Verrelle, T. Filleron +11 more
2013European Journal of Cancer55 citations
Semantic Scholar
Association of the Variants CASP8 D302H and CASP10 V410I with Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
C. Engel, B. Versmold, B. Wappenschmidt, J. Simard +64 more
2010Cancer Epidemiology, Biomarkers and Prevention55 citations Open access
Semantic Scholar
Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway
P. Deshors, C. Toulas, F. Arnauduc, Laure Malric +8 more
2019Cell Death and Disease54 citations Open access
Semantic Scholar
FGFR1 Induces Glioblastoma Radioresistance through the PLCγ/Hif1α Pathway.
Valérie Gouazé-Andersson, C. Delmas, M. Taurand, Judith Martinez-Gala +4 more
2016Cancer Research53 citations Open access
Semantic Scholar
Phase I trial of tipifarnib (R115777) concurrent with radiotherapy in patients with glioblastoma multiforme.
E. Moyal, A. Laprie, M. Delannes, M. Poublanc +8 more
2007International Journal of Radiation Oncology, Biology, Physics49 citations
Semantic Scholar
Farnesylated RhoB inhibits radiation-induced mitotic cell death and controls radiation-induced centrosome overduplication
J. Milia, F. Teyssier, F. Dalenc, Isabelle Ader +8 more
2005Cell Death and Differentiation49 citations
Semantic Scholar
Int6/eIF3e Is Essential for Proliferation and Survival of Human Glioblastoma Cells
J. Sesen, A. Cammas, S. Scotland, Bertand Elefterion +7 more
2014International Journal of Molecular Sciences43 citations Open access
Semantic Scholar
Radiation-induced mitotic cell death and glioblastoma radioresistance: a new regulating pathway controlled by integrin-linked kinase, hypoxia-inducible factor 1 alpha and survivin in U87 cells.
Olivia Lanvin, S. Monferran, C. Delmas, B. Couderc +2 more
2013European Journal of Cancer43 citations
Semantic Scholar
Alpha6-Integrin Regulates FGFR1 Expression through the ZEB1/YAP1 Transcription Complex in Glioblastoma Stem Cells Resulting in Enhanced Proliferation and Stemness
A. Kowalski‐Chauvel, Valérie Gouazé-Andersson, L. Baricault, E. Martin +4 more
2019Cancers42 citations Open access
Semantic Scholar
FGFR1/FOXM1 pathway: a key regulator of glioblastoma stem cells radioresistance and a prognosis biomarker
Valérie Gouazé-Andersson, Marie-Julie Ghérardi, A. Lemarié, J. Gilhodes +4 more
2018OncoTarget42 citations Open access
Semantic Scholar
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer
G. Figlioli, M. Bogliolo, Irene Catucci, Laura Caleca +473 more
2019npj Breast Cancer41 citations Open access
Semantic Scholar
Alpha-6 integrin promotes radioresistance of glioblastoma by modulating DNA damage response and the transcription factor Zeb1
A. Kowalski‐Chauvel, A. Modesto, Valérie Gouazé-Andersson, L. Baricault +6 more
2018Cell Death and Disease40 citations Open access
Semantic Scholar
The farnesyltransferase inhibitor FTI-277 suppresses the 24-kDa FGF2-induced radioresistance in HeLa cells expressing wild-type RAS.
E. Cohen-Jonathan, C. Toulas, Isabelle Ader, Sylvia Monteil +6 more
1999Radiation Research39 citations
Semantic Scholar
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers
Juliette Coignard, M. Lush, J. Beesley, T. O'Mara +388 more
2021Nature Communications37 citations Open access
Semantic Scholar
Increased expression of a COOH‐truncated nucleophosmin resulting from alternative splicing is associated with cellular resistance to ionizing radiation in HeLa cells
F. Dalenc, J. Drouet, I. Ader, C. Delmas +4 more
2002International Journal of Cancer36 citations Open access
Semantic Scholar
Preclinical evidence that SSR128129E--a novel small-molecule multi-fibroblast growth factor receptor blocker--radiosensitises human glioblastoma.
I. Ader, C. Delmas, Nicolas Skuli, J. Bonnet +4 more
2014European Journal of Cancer32 citations
Semantic Scholar
The STEMRI trial: Magnetic resonance spectroscopy imaging can define tumor areas enriched in glioblastoma stem-like cells
A. Lemarié, V. Lubrano, C. Delmas, A. Lusque +10 more
2023Science Advances31 citations Open access
Semantic Scholar
Inhibiting Integrin β8 to Differentiate and Radiosensitize Glioblastoma-Initiating Cells
Laure Malric, S. Monferran, C. Delmas, F. Arnauduc +13 more
2018Molecular Cancer Research31 citations Open access
Semantic Scholar
The c.5242C>A BRCA1 missense variant induces exon skipping by increasing splicing repressors binding
S. Millevoi, S. Bernat, D. Telly, F. Fouque +4 more
2010Breast Cancer Research and Treatment31 citations
Semantic Scholar
Prognostic value of uPA and p53 accumulation measured by quantitative biochemical assays in 1245 primary breast cancer patients: a multicentre study
P. Broët, F. Spyratos, S. Romain, V. Quillien +5 more
1999British Journal of Cancer31 citations Open access
Semantic Scholar
Classification of 101 BRCA1 and BRCA2 variants of uncertain significance by cosegregation study: A powerful approach.
S. Caputo, L. Golmard, M. Léoné, F. Damiola +156 more
2021American Journal of Human Genetics30 citations Open access
Semantic Scholar
Breast cancer risk in BRCA1 and BRCA2 mutation carriers and polyglutamine repeat length in the AIB1 gene
D. Hughes, Sophie M. Ginolhac, I. Coupier, L. Barjhoux +26 more
2005International Journal of Cancer29 citations Open access
Semantic Scholar
Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM‐46228
G. Prevost, A. Pradines, Marie‐Christine Brezak, M. Lonchampt +7 more
2001International Journal of Cancer27 citations Open access
Semantic Scholar
Rare germline large rearrangements in the BRCA1/2 genes and eight candidate genes in 472 patients with breast cancer predisposition
E. Rouleau, B. Jesson, A. Briaux, C. Noguès +23 more
2012Breast Cancer Research and Treatment25 citations
Semantic Scholar
Continuous Infusion of Cilengitide Plus Chemoradiotherapy for Patients With Stage III Non-Small-cell Lung Cancer: A Phase I Study.
C. Massabeau, J. Khalifa, T. Filleron, A. Modesto +13 more
2017Clinical Lung Cancer24 citations
Semantic Scholar
Basic fibroblast growth factor-2/beta3 integrin expression profile: signature of local progression after chemoradiotherapy for patients with locally advanced non-small-cell lung cancer.
C. Massabeau, I. Rouquette, V. Lauwers-Cancès, J. Mazières +6 more
2009International Journal of Radiation Oncology, Biology, Physics22 citations
Semantic Scholar
Potential prognostic value in human breast cancer of cytosolic Nme1 protein detection using an original hen specific antibody.
C. Toulas, J. Mihura, C. de Balincourt, B. Marques +4 more
1996British Journal of Cancer22 citations Open access
Semantic Scholar
Clinical relevance of 8q23, 15q13 and 18q21 SNP genotyping to evaluate colorectal cancer risk
S. Baert-Desurmont, F. Charbonnier, E. Houivet, L. Ippolito +52 more
2015European Journal of Human Genetics21 citations Open access
Semantic Scholar
Simplified identification of Lynch syndrome: a prospective, multicenter study.
D. Bonnet, J. Sèlves, C. Toulas, M. Danjoux +12 more
2012Digestive and Liver Disease21 citations
Semantic Scholar
Common BRCA2 variants and modification of breast and ovarian cancer risk in BRCA1 mutation carriers.
D. Hughes, Sophie M. Ginolhac, I. Coupier, M. Corbex +30 more
2005Cancer Epidemiology, Biomarkers and Prevention20 citations
Semantic Scholar
BRCA1 wild-type allele modifies risk of ovarian cancer in carriers of BRCA1 germ-line mutations.
Sophie M. Ginolhac, S. Gad, M. Corbex, B. Bressac-de Paillerets +28 more
2003Cancer Epidemiology, Biomarkers and Prevention20 citations
Semantic Scholar
The RND1 Small GTPase: Main Functions and Emerging Role in Oncogenesis
Laetitia Mouly, J. Gilhodes, A. Lemarié, E. Cohen-Jonathan Moyal +4 more
2019International Journal of Molecular Sciences18 citations Open access
Semantic Scholar
Translation reprogramming by eIF3 linked to glioblastoma resistance
J. Bertorello, J. Sesen, J. Gilhodes, S. Evrard +10 more
2020NAR Cancer17 citations Open access
Semantic Scholar
Association and performance of polygenic risk scores for breast cancer among French women presenting or not a familial predisposition to the disease.
Yue Jiao, T. Truong, Séverine Eon-Marchais, N. Mebirouk +56 more
2022European Journal of Cancer15 citations Open access
Semantic Scholar

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