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Ingrid C Rulifson · SciRah

Researcher profile · Semantic Scholar

Ingrid C Rulifson

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Ingrid C Rulifson — researcher profile on SciRah

h-index: 19
Works: 37
Citations: 2,706

Most-cited papers

Growth inhibitors promote differentiation of insulin-producing tissue from embryonic stem cells
Y. Hori, Ingrid C Rulifson, Bernette C Tsai, Jeremy J. Heit +2 more
2002Proceedings of the National Academy of Sciences of the United States of America463 citations Open access
Semantic Scholar
CD28 costimulation promotes the production of Th2 cytokines.
Ingrid C Rulifson, A. Sperling, P. Fields, F. Fitch +1 more
1997Journal of Immunology350 citations Open access
Semantic Scholar
Wnt signaling regulates pancreatic β cell proliferation
Ingrid C Rulifson, S. Karnik, P. Heiser, D. ten Berge +6 more
2007Proceedings of the National Academy of Sciences of the United States of America317 citations Open access
Semantic Scholar
CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation.
Anne I. Sperling, Julie A. Auger, B. Ehst, Ingrid C Rulifson +2 more
1996Journal of Immunology263 citations
Semantic Scholar
Multiomics study of nonalcoholic fatty liver disease
G. Sveinbjornsson, M. Ulfarsson, Rosa B. Thorolfsdottir, B. A. Jónsson +42 more
2022Nature Genetics207 citations Open access
Semantic Scholar
Wnt signaling regulates pancreatic beta cell proliferation.
Ingrid C Rulifson, S. Karnik, P. Heiser, D. ten Berge +6 more
2007Proceedings of the National Academy of Sciences of the United States of America197 citations
Semantic Scholar
Cutting edge: blockade of the CD28/B7 costimulatory pathway inhibits intestinal allograft rejection mediated by CD4+ but not CD8+ T cells.
K. Newell, G. He, Zhong Guo, Oliver Kim +6 more
1999Journal of Immunology167 citations Open access
Semantic Scholar
Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response.
Lars Fugger, S. Michie, Ingrid C Rulifson, C. Lock +1 more
1994Proceedings of the National Academy of Sciences of the United States of America101 citations Open access
Semantic Scholar
Regulation of C-C chemokine production by murine T cells by CD28/B7 costimulation.
Kevan C. Herold, Jing Lu, Ingrid C Rulifson, V. Vezys +3 more
1997Journal of Immunology96 citations Open access
Semantic Scholar
Regulated β-Cell Regeneration in the Adult Mouse Pancreas
D. Cano, Ingrid C Rulifson, P. Heiser, L. Swigart +5 more
2008Diabetes93 citations Open access
Semantic Scholar
Regulated beta-cell regeneration in the adult mouse pancreas.
D. Cano, Ingrid C Rulifson, P. Heiser, L. Swigart +5 more
2008Diabetes67 citations
Semantic Scholar
Different Mechanisms of Cardiac Allograft Rejection in Wildtype and CD28‐deficient Mice
G. Szot, P. Zhou, Ingrid C Rulifson, Jun Wang +6 more
2001American Journal of Transplantation55 citations Open access
Semantic Scholar
Glucagon receptor antagonist-mediated improvements in glycemic control are dependent on functional pancreatic GLP-1 receptor.
W. Gu, K. Winters, A. Motani, R. Komorowski +12 more
2010American Journal of Physiology. Endocrinology and Metabolism51 citations
Semantic Scholar
Trefoil Factor 3 (TFF3) Is Regulated by Food Intake, Improves Glucose Tolerance and Induces Mucinous Metaplasia
Hongfei Ge, Jonitha Gardner, Xiaosu Wu, Ingrid C Rulifson +18 more
2015PLoS ONE42 citations Open access
Semantic Scholar
Identification of Human Islet Amyloid Polypeptide as a BACE2 Substrate
Ingrid C Rulifson, P. Cao, Li Miao, D. Kopecký +13 more
2016PLoS ONE30 citations Open access
Semantic Scholar
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Junedh M. Amrute, In-Hyuk Jung, Tracy Yamawaki, Wen-Ling Lin +35 more
2026Science24 citations Open access
Semantic Scholar
Inhibition of secreted frizzled-related protein 5 improves glucose metabolism.
Ingrid C Rulifson, Jiangwen Z Majeti, Yu-Mei Xiong, A. Hamburger +11 more
2014American Journal of Physiology. Endocrinology and Metabolism23 citations
Semantic Scholar
KLF15 cistromes reveal a hepatocyte pathway governing plasma corticosteroid transport and systemic inflammation
Zhenghi Jiang, Selma Z Elsarrag, Qiming Duan, Edward L LaGory +11 more
2022Science Advances21 citations Open access
Semantic Scholar
Human CD1d Functions as a Transplantation Antigen and a Restriction Element in Mice1
Bin Wang, T. Chun, Ingrid C Rulifson, M. Exley +2 more
2001Journal of Immunology19 citations Open access
Semantic Scholar
The fatty liver disease–causing protein PNPLA3-I148M alters lipid droplet–Golgi dynamics
David J. Sherman, Lei Liu, Jennifer L Mamrosh, Jiansong Xie +6 more
2024Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar
In Vitro and in Vivo Analyses Reveal Profound Effects of Fibroblast Growth Factor 16 as a Metabolic Regulator*
Ingrid C Rulifson, Patrick J. Collins, Li Miao, D. Nojima +10 more
2016Journal of Biological Chemistry17 citations Open access
Semantic Scholar
A small number of residues in the class II molecule I-Au confer the ability to bind the myelin basic protein peptide Ac1-11.
C. Pearson, Anand M. Gautam, Ingrid C Rulifson, R. Liblau +1 more
1999Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar
Identification and Optimization of a Minor Allele-Specific siRNA to Prevent PNPLA3 I148M-Driven Nonalcoholic Fatty Liver Disease
Justin K. Murray, J. Long, Lei Liu, Shivani Singh +14 more
2021Nucleic Acid Therapeutics16 citations Open access
Semantic Scholar
Evaluating insulin secretagogues in a humanized mouse model with functional human islets.
Jian Luo, K. Nguyen, Michael Chen, Thanhvien Tran +12 more
2013Metabolism: Clinical and Experimental15 citations
Semantic Scholar
The fatty liver disease-causing protein PNPLA3-I148M alters lipid droplet-Golgi dynamics
David J. Sherman, Lei Liu, Jennifer L Mamrosh, Jiansong Xie +6 more
2023bioRxiv11 citations Open access
Semantic Scholar
Soluble CLEC2 Extracellular Domain Improves Glucose and Lipid Homeostasis by Regulating Liver Kupffer Cell Polarization
Xinle Wu, Jun Zhang, Hongfei Ge, Jamila Gupte +10 more
2015EBioMedicine9 citations Open access
Semantic Scholar
PNPLA3-I148M is a Neomorph that Interferes with Two Primary Hepatic Triglyceride Clearance Pathways
David J. Sherman, Lei Liu, Edward L. LaGory, Preston Fordstrom +7 more
2024bioRxiv8 citations Open access
Semantic Scholar
Targeting RUNX1 in Macrophages Facilitates Cardiac Recovery
Junedh M. Amrute, Ada Zhu, Yun-Ling Pai, Melissa Hector-Greene +42 more
2025bioRxiv6 citations Open access
Semantic Scholar
Targeting Modulated Vascular Smooth Muscle Cells in Atherosclerosis via FAP-Directed Immunotherapy
Junedh M. Amrute, In-Hyuk Jung, Tracy Yamawaki, Andrea L. Bredemeyer +30 more
2025bioRxiv6 citations Open access
Semantic Scholar
Regulated -Cell Regeneration in the Adult Mouse
P. A. Cano, Ingrid C Rulifson, P. Heiser, L. Swigart +5 more
20081 citations
Semantic Scholar
Use of a Transgenic Human PNPLA3I148M Knock-in Mouse for Translational Safety Evaluations of siRNA Therapeutics
B. Brooks, Artem A. Shkumatov, Jackson Kalanzi, Kim Henderson Park +8 more
2025Nucleic Acid Therapeutics0 citations Open access
Semantic Scholar
Abstract 2651 PNPLA3-I148M is a Neomorph that Interferes with Two Primary Hepatic Triglyceride Clearance Pathways
David J. Sherman, Lei Liu, Edward L LaGory, Preston Fordstrom +5 more
2025Journal of Biological Chemistry0 citations Open access
Semantic Scholar
RAB18 regulates extrahepatic siRNA-mediated gene silencing efficacy
Jiamiao Lu, Jasper Lee, E. Yuan, Devin L Wakefield +15 more
2024Molecular Therapy: Nucleic Acids0 citations Open access
Semantic Scholar
Rnai constructs for inhibiting pnpla3 expression and methods of use thereof
Ingrid C Rulifson, Justin K. Murray, Mike Ollmann, O. Homann
20180 citations
Semantic Scholar
Antigen and a Restriction Element in Mice Human CD 1 d Functions as a Transplantation
Bin Wang, T. Chun, Ingrid C Rulifson, M. Exley +2 more
20010 citations
Semantic Scholar
A CLASS II‐ALLOSPECIFIC TCR CD4+ TRANSGENIC MOUSE DEMONSTRATES THAT COSTIMULATION IS NOT REQUIRED FOR THE REJECTION OF SKIN ALLOGRAFTS VIA THE DIRECT PATHWAY.: Abstract# 497 Poster Board #‐Session: P137‐II
Ingrid C Rulifson, G. Szot, E. Palmer, J. Bluestone
20000 citations Open access
Semantic Scholar
But + Allograft Rejection Mediated by CD4 Costimulatory Pathway Inhibits Intestinal Cutting Edge: Blockade of the CD28/B7
R. Thistlethwaite, J. Bluestone, G. Szot, Ingrid C Rulifson +7 more
0 citations
Semantic Scholar

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