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Andrea L. Bredemeyer · SciRah

Researcher profile · Semantic Scholar

Andrea L. Bredemeyer

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Andrea L. Bredemeyer — researcher profile on SciRah

h-index: 35
Works: 83
Citations: 6,240

Most-cited papers

The Human Heart Contains Distinct Macrophage Subsets with Divergent Origins and Functions
G. Bajpai, Caralin Schneider, Nicole Rose Wong, Andrea L. Bredemeyer +10 more
2018Nature Medicine638 citations Open access
Semantic Scholar
Tissue Resident CCR2− and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury
G. Bajpai, Andrea L. Bredemeyer, Wenjun Li, Konstantin Zaitsev +11 more
2019Circulation Research623 citations Open access
Semantic Scholar
ATM stabilizes DNA double-strand-break complexes during V(D)J recombination
Andrea L. Bredemeyer, G. Sharma, Ching‐Yu Huang, Beth A. Helmink +7 more
2006Nature428 citations
Semantic Scholar
Single-cell transcriptomics reveals cell-type-specific diversification in human heart failure
Andrew L. Koenig, I. Shchukina, Junedh M. Amrute, P. Andhey +10 more
2022Nature Cardiovascular Research413 citations Open access
Semantic Scholar
Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation.
Wenjun Li, Guo-Shuai Feng, J. Gauthier, I. Lokshina +17 more
2019Journal of Clinical Investigation396 citations Open access
Semantic Scholar
Targeting immune–fibroblast cell communication in heart failure
Junedh M. Amrute, Xin Luo, Vinay R. Penna, Steven Yang +32 more
2024Nature266 citations Open access
Semantic Scholar
The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart.
Alberto Ciccia, Andrea L. Bredemeyer, M. Sowa, M. Terret +3 more
2009Genes & Development213 citations Open access
Semantic Scholar
Resident Cardiac Macrophages Mediate Adaptive Myocardial Remodeling
Nicole Rose Wong, Jayaram Mohan, B. Kopecky, Shuchi Guo +26 more
2021bioRxiv209 citations Open access
Semantic Scholar
Formation of Dynamic γ-H2AX Domains along Broken DNA Strands is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin
Velibor Savic, B. Yin, Nancy L. Maas, Andrea L. Bredemeyer +5 more
2009Molecules and Cells209 citations Open access
Semantic Scholar
Recurrent Hemizygous Deletions in Cancers May Optimize Proliferative Potential
Nicole L. Solimini, Qi-Kai Xu, C. Mermel, Anthony C. Liang +9 more
2012Science203 citations Open access
Semantic Scholar
ATM prevents the persistence and propagation of chromosome breaks in lymphocytes.
E. Callen, M. Jankovic, Simone Difilippantonio, J. A. Daniel +10 more
2007Cell193 citations Open access
Semantic Scholar
Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into blood
Nicholas C. Borcherding, Wentong Jia, Rocky Giwa, Rachael L. Field +17 more
2022Cell Metabolism159 citations Open access
Semantic Scholar
Proteasome Activator PA200 Is Required for Normal Spermatogenesis
B. Khor, Andrea L. Bredemeyer, Ching‐Yu Huang, Isaiah R. Turnbull +7 more
2006Molecular and Cellular Biology157 citations Open access
Semantic Scholar
DNA double strand breaks activate a multi-functional genetic program in developing lymphocytes
Andrea L. Bredemeyer, Beth A. Helmink, C. Innes, B. Calderon +13 more
2008Nature153 citations Open access
Semantic Scholar
Expansion of Pathogenic Cardiac Macrophages in Immune Checkpoint Inhibitor Myocarditis
Pan Ma, Jing Liu, Juan Qin, Lu-Lu Lai +17 more
2023Circulation142 citations Open access
Semantic Scholar
Dynamic regulation of c‐Myc proto‐oncogene expression during lymphocyte development revealed by a GFP‐c‐Myc knock‐in mouse
Ching‐Yu Huang, Andrea L. Bredemeyer, Laura M. Walker, C. Bassing +1 more
2008European Journal of Immunology134 citations
Semantic Scholar
SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
Adam Leitman Bailey, O. Dmytrenko, Lina Greenberg, Andrea L. Bredemeyer +25 more
2021JACC: Basic to Translational Science130 citations Open access
Semantic Scholar
A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability
B. C. O'Connell, Britt Adamson, John R. Lydeard, M. Sowa +6 more
2010Molecules and Cells124 citations Open access
Semantic Scholar
CCL17 aggravates myocardial injury by suppressing recruitment of regulatory T-cells
Guo-Shuai Feng, G. Bajpai, Pan Ma, Andrew L. Koenig +7 more
2022Circulation111 citations Open access
Semantic Scholar
Intrathymic proliferation wave essential for Vα14+ natural killer T cell development depends on c-Myc
Marei Dose, B. Sleckman, Jin Han, Andrea L. Bredemeyer +2 more
2009Proceedings of the National Academy of Sciences of the United States of America109 citations Open access
Semantic Scholar
MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks
Beth A. Helmink, Andrea L. Bredemeyer, Baeck-seung Lee, Ching‐Yu Huang +7 more
2009Journal of Experimental Medicine100 citations Open access
Semantic Scholar
MRI is a DNA Damage Response Adaptor during Classical Non-Homologous End Joining
Putzer J. Hung, Britney Johnson, Bo-Ruei Chen, Andrea K. Byrum +17 more
2018Molecules and Cells96 citations Open access
Semantic Scholar
β-Catenin induces T-cell transformation by promoting genomic instability
Marei Dose, A. Emmanuel, Julie Chaumeil, Jiang-Wen Zhang +12 more
2013Proceedings of the National Academy of Sciences of the United States of America70 citations Open access
Semantic Scholar
Pediatric and adult dilated cardiomyopathy represent distinct pathological entities.
Meghna D. Patel, Jayaram Mohan, Caralin Schneider, G. Bajpai +5 more
2017JCI Insight68 citations Open access
Semantic Scholar
Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation
E. Gapud, Yair Dorsett, B. Yin, E. Callen +9 more
2011Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
Semantic Scholar
Hematopoietic Stem Cell Differentiation Regulated by a Single Ubiquitin Ligase: Substrate Complex
L. Reavie, G. D. Gatta, K. Crusio, Beatriz Aranda-Orgilles +11 more
2010Nature Immunology68 citations Open access
Semantic Scholar
Defining cardiac functional recovery in end-stage heart failure at single-cell resolution
Junedh M. Amrute, Lu-Lu Lai, Pan Ma, Andrew L. Koenig +16 more
2023Nature Cardiovascular Research67 citations Open access
Semantic Scholar
Donor Macrophages Modulate Rejection after Heart Transplantation
B. Kopecky, Dun Hao, Junedh M. Amrute, Chieh-Yu Lin +8 more
2021bioRxiv65 citations Open access
Semantic Scholar
Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination
B. Yin, Velibor Savic, M. Juntilla, Andrea L. Bredemeyer +5 more
2009Journal of Experimental Medicine64 citations Open access
Semantic Scholar
Aberrant V(D)J joining in ATM-deficient lymphocytes is dependent on non-homologous DNA end joining
Andrea L. Bredemeyer, Ching‐Yu Huang, Laura M. Walker, C. Bassing +1 more
2008Journal of Immunology52 citations Open access
Semantic Scholar
Deficiency of XLF and PAXX prevents DNA double-strand break repair by non-homologous end joining in lymphocytes
Putzer J. Hung, Bo-Ruei Chen, R. George, Caleb Liberman +5 more
2017Cell Cycle47 citations Open access
Semantic Scholar
SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
Adam Leitman Bailey, O. Dmytrenko, Lina Greenberg, Andrea L. Bredemeyer +25 more
2020bioRxiv46 citations Open access
Semantic Scholar
Aberrantly resolved RAG-mediated DNA breaks in Atm-deficient lymphocytes target chromosomal breakpoints in cis
G. Mahowald, J. M. Baron, M. Mahowald, S. Kulkarni +3 more
2009Proceedings of the National Academy of Sciences of the United States of America42 citations Open access
Semantic Scholar
Functional Intersection of ATM and DNA-Dependent Protein Kinase Catalytic Subunit in Coding End Joining during V(D)J Recombination
Baeck-seung Lee, E. Gapud, Shi-Chuan Zhang, Yair Dorsett +12 more
2013Molecular and Cellular Biology39 citations Open access
Semantic Scholar
Modeling altered T-cell development with induced pluripotent stem cells from patients with RAG1-dependent immune deficiencies.
Patrick M. Brauer, Itai M. Pessach, E. Clarke, J. Rowe +19 more
2016Blood38 citations Open access
Semantic Scholar
Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis
Junedh M. Amrute, Xin Luo, Vinay Penna, Andrea L. Bredemeyer +22 more
2023Research Square29 citations Open access
Semantic Scholar
HCoDES reveals chromosomal DNA end structures with single nucleotide resolution
Yair Dorsett, Yanjiao Zhou, Anthony T. Tubbs, Bo-Ruei Chen +14 more
2014Molecules and Cells29 citations Open access
Semantic Scholar
Visualizing Immune Checkpoint Inhibitors Derived Inflammation in Atherosclerosis
Lanlan Lou, L. Detering, Hannah P. Luehmann, Junedh M. Amrute +9 more
2024Circulation Research25 citations Open access
Semantic Scholar
Development of a CD163-Targeted PET Radiotracer That Images Resident Macrophages in Atherosclerosis
Xiu-Li Zhang, G. Heo, Alexandria Li, Divangana Lahad +17 more
2024Journal of Nuclear Medicine25 citations Open access
Semantic Scholar
Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy
Junedh M. Amrute, In-Hyuk Jung, Tracy Yamawaki, Wen-Ling Lin +35 more
2026Science24 citations Open access
Semantic Scholar
Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages
Michael D. Iglesia, R. Jayasinghe, Siqi Chen, Nadezhda V. Terekhanova +56 more
2024Nature Cancer20 citations Open access
Semantic Scholar
CCL17 Protects Against Viral Myocarditis by Suppressing the Recruitment of Regulatory T Cells
Guo-Shuai Feng, Cuige Zhu, Chieh-Yu Lin, Andrea L. Bredemeyer +3 more
2023Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease19 citations Open access
Semantic Scholar
KAP-1 Promotes Resection of Broken DNA Ends Not Protected by γ-H2AX and 53BP1 in G1-Phase Lymphocytes
Anthony T. Tubbs, Yair Dorsett, Elizabeth A. W. Chan, Beth A. Helmink +10 more
2014Molecular and Cellular Biology19 citations Open access
Semantic Scholar
XLF and H2AX function in series to promote replication fork stability
Bo-Ruei Chen, A. Quinet, Andrea K. Byrum, Jessica Jackson +8 more
2019Journal of Cell Biology18 citations Open access
Semantic Scholar
Hypoxia sensing in resident cardiac macrophages regulates monocyte fate specification following ischemic heart injury
F. Kadyrov, Andrew L. Koenig, Junedh M. Amrute, Dun Hao +14 more
2024Nature Cardiovascular Research14 citations Open access
Semantic Scholar
Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages
Michael D. Iglesia, R. Jayasinghe, Siqi Chen, Nadezhda V. Terekhanova +56 more
2023bioRxiv11 citations Open access
Semantic Scholar
Targeting the Immune-Fibrosis Axis in Myocardial Infarction and Heart Failure
Junedh M. Amrute, Xin Luo, Vinay Penna, Andrea L. Bredemeyer +22 more
2022bioRxiv11 citations Open access
Semantic Scholar
Derivation of extra-embryonic and intra-embryonic macrophage lineages from human pluripotent stem cells.
Andrea L. Bredemeyer, Junedh M. Amrute, Andrew L. Koenig, Rachel A. Idol +9 more
2022Development10 citations Open access
Semantic Scholar
Chemokine Receptor 2 Is a Theranostic Biomarker for Abdominal Aortic Aneurysms
Santiago Elizondo-Benedetto, Sergio Sastriques-Dunlop, L. Detering, Batool Arif +21 more
2025JACC: Basic to Translational Science7 citations Open access
Semantic Scholar
A Critical Role for the Mitochondrial Pyruvate Carrier in Hepatic Stellate Cell Activation
Mohammad Habibi, Daniel Ferguson, Sophie J. Eichler, Mandy M. Chan +12 more
2025Cellular and Molecular Gastroenterology and Hepatology7 citations Open access
Semantic Scholar

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