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K. Rapti · SciRah

Researcher profile · Semantic Scholar

K. Rapti

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K. Rapti — researcher profile on SciRah

h-index: 23
Works: 56
Citations: 1,568

Most-cited papers

Neutralizing antibodies against AAV serotypes 1, 2, 6, and 9 in sera of commonly used animal models.
K. Rapti, Vedell Louis-Jeune, E. Kohlbrenner, K. Ishikawa +4 more
2012Molecular Therapy164 citations Open access
Semantic Scholar
SUMO-1 Gene Transfer Improves Cardiac Function in a Large-Animal Model of Heart Failure
L. Tilemann, Ahyoung Lee, K. Ishikawa, J. Aguero +6 more
2013Science Translational Medicine120 citations
Semantic Scholar
Identification of circular RNAs with host gene-independent expression in human model systems for cardiac differentiation and disease.
Dominik Siede, K. Rapti, A. Górska, H. Katus +8 more
2017Journal of Molecular and Cellular Cardiology113 citations
Semantic Scholar
Pulmonary Targeting of Adeno-associated Viral Vectors by Next-generation Sequencing-guided Screening of Random Capsid Displayed Peptide Libraries.
J. Körbelin, T. Sieber, S. Michelfelder, L. Lunding +10 more
2016Molecular Therapy86 citations Open access
Semantic Scholar
Cell-specific CRISPR–Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins
M. D. Hoffmann, S. Aschenbrenner, Stefanie Grosse, K. Rapti +7 more
2019Nucleic Acids Research82 citations Open access
Semantic Scholar
Cardiac I-1c overexpression with reengineered AAV improves cardiac function in swine ischemic heart failure.
K. Ishikawa, K. Fish, L. Tilemann, K. Rapti +16 more
2014Molecular Therapy82 citations Open access
Semantic Scholar
Stimulating Myocardial Regeneration with Periostin Peptide in Large Mammals Improves Function Post-Myocardial Infarction but Increases Myocardial Fibrosis
D. Ladage, E. Yaniz-Galende, K. Rapti, K. Ishikawa +9 more
2013PLoS ONE68 citations Open access
Semantic Scholar
Alterations in the heart mitochondrial proteome in a desmin null heart failure model.
M. Fountoulakis, E. Soumaka, K. Rapti, M. Mavroidis +4 more
2005Journal of Molecular and Cellular Cardiology68 citations
Semantic Scholar
Adeno-Associated Viruses (AAV) and Host Immunity – A Race Between the Hare and the Hedgehog
K. Rapti, D. Grimm
2021Frontiers in Immunology59 citations Open access
Semantic Scholar
Delivery of gelfoam-enabled cells and vectors into the pericardial space using a percutaneous approach in a porcine model
D. Ladage, I. Turnbull, K. Ishikawa, Y. Takewa +8 more
2011Gene Therapy59 citations Open access
Semantic Scholar
Effectiveness of gene delivery systems for pluripotent and differentiated cells
K. Rapti, F. Stillitano, I. Karakikes, M. Nonnenmacher +3 more
2015Molecular Therapy: Methods & Clinical Development57 citations Open access
Semantic Scholar
Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy
Markus Grosch, L. Schraft, Adrian Chan, Leonie Küchenhoff +14 more
2022bioRxiv49 citations Open access
Semantic Scholar
Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy
I. El-Battrawy, Zhi-Han Zhao, H. Lan, Xin Li +24 more
2018Circulation Genomic and Precision Medicine47 citations Open access
Semantic Scholar
Cell-specific CRISPR/Cas9 activation by microRNA-dependent expression of anti-CRISPR proteins
M. D. Hoffmann, S. Aschenbrenner, Stefanie Grosse, K. Rapti +6 more
2018bioRxiv44 citations Open access
Semantic Scholar
Targeted Gene Therapy for the Treatment of Heart Failure
K. Rapti, Antoine H. Chaanine, R. Hajjar
2011Canadian Journal of Cardiology43 citations Open access
Semantic Scholar
Genetic Ablation of TASK-1 (Tandem of P Domains in a Weak Inward Rectifying K+ Channel-Related Acid-Sensitive K+ Channel-1) (K2P3.1) K+ Channels Suppresses Atrial Fibrillation and Prevents Electrical Remodeling.
C. Schmidt, F. Wiedmann, C. Beyersdorf, Zhi-Han Zhao +17 more
2019Circulation: Arrhythmia and Electrophysiology38 citations Open access
Semantic Scholar
Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure.
O. Müller, M. Heckmann, L. Ding, K. Rapti +19 more
2018Cardiovascular Research37 citations
Semantic Scholar
Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1.SERCA2a enhances gene transfer in porcine hearts.
I. Karakikes, Lahouaria Hadri, K. Rapti, D. Ladage +9 more
2012Molecular Therapy37 citations Open access
Semantic Scholar
Quantification of AAV Particle Titers by Infrared Fluorescence Scanning of Coomassie-Stained Sodium Dodecyl Sulfate–Polyacrylamide Gels
E. Kohlbrenner, Els Henckaerts, K. Rapti, R. Gordon +3 more
2012Human Gene Therapy Methods34 citations Open access
Semantic Scholar
Aortic Implantation of Mesenchymal Stem Cells after Aneurysm Injury in a Porcine Model
I. Turnbull, Lahouaria Hadri, K. Rapti, M. Sadek +6 more
2011Journal of Surgical Research34 citations Open access
Semantic Scholar
Polytene Chromosomes as Tools in the Genetic Analysis of the Mediterranean Fruit Fly, Ceratitis Capitata
A. Gariou-Papalexiou, P. Gourzi, A. Delprat, D. Kritikou +4 more
2002Genetica31 citations
Semantic Scholar
Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy
M. Ramos-Kuri, K. Rapti, Hind Mehel, Shi-Hong Zhang +10 more
2015Biochimica et Biophysica Acta26 citations Open access
Semantic Scholar
Opposite effects of catalase and MnSOD ectopic expression on stress induced defects and mortality in the desmin deficient cardiomyopathy model
K. Rapti, A. Diokmetzidou, I. Kloukina, D. Milner +3 more
2017Free Radical Biology & Medicine23 citations
Semantic Scholar
Altered spatiotemporal dynamics of the mitochondrial membrane potential in the hypertrophied heart.
Hong-Wei Jin, R. D. Nass, Paul J Joudrey, A. Lyon +3 more
2010Biophysical Journal23 citations Open access
Semantic Scholar
AAV9-mediated gene transfer of desmin ameliorates cardiomyopathy in desmin-deficient mice
M. Heckmann, R. Bauer, A. Jungmann, L. Winter +7 more
2016Gene Therapy21 citations Open access
Semantic Scholar
AAV-mediated cardiac gene transfer of wild-type desmin in mouse models for recessive desminopathies
T. Ruppert, M. Heckmann, K. Rapti, D. Schultheis +7 more
2020Gene Therapy19 citations Open access
Semantic Scholar
Active Inhibitor-1 Maintains Protein Hyper-Phosphorylation in Aging Hearts and Halts Remodeling in Failing Hearts
Tracy J. Pritchard, Y. Kawase, K. Haghighi, Ahmad Anjak +9 more
2013PLoS ONE18 citations Open access
Semantic Scholar
Cell-Based Measurement of Neutralizing Antibodies Against Adeno-Associated Virus (AAV).
A. Jungmann, O. Müller, K. Rapti
2017Methods in molecular biology16 citations
Semantic Scholar
AAV-mediated overexpression of CPT1B protects from cardiac hypertrophy and heart failure in a murine pressure overload model
A. Kliesow Remes, T. Ruf, Tinatin Zurashvili, L. Ding +18 more
2025Basic Research in Cardiology12 citations Open access
Semantic Scholar
AAV-Mediated Expression of AP-1-Neutralizing RNA Decoy Oligonucleotides Attenuates Transplant Vasculopathy in Mouse Aortic Allografts
A. Remes, Maximilian Franz, F. Mohr, A. Weber +8 more
2019Molecular Therapy: Methods & Clinical Development11 citations Open access
Semantic Scholar
Membrane remodelling triggers maturation of excitation–contraction coupling in 3D-shaped human-induced pluripotent stem cell-derived cardiomyocytes
F. Kermani, M. Mosqueira, Kyra Peters, E. Lemma +6 more
2023Basic Research in Cardiology10 citations Open access
Semantic Scholar
Induction of Hepatitis E Virus Anti-ORF3 Antibodies from Systemic Administration of a Muscle-Specific Adeno-Associated Virus (AAV) Vector
L. Maurer, J. El Andari, K. Rapti, Laura Spreyer +3 more
2022Viruses10 citations Open access
Semantic Scholar
Locally Targeted Cardiac Gene Delivery by AAV Microbubble Destruction in a Large Animal Model
P. Schlegel, Regina Huditz, E. Meinhardt, K. Rapti +6 more
2016Human Gene Therapy Methods10 citations
Semantic Scholar
Ligand-activated RXFP1 gene therapy ameliorates pressure overload-induced cardiac dysfunction.
N. Sasipong, P. Schlegel, J. Wingert, C. Lederer +9 more
2021Molecular Therapy7 citations Open access
Semantic Scholar
Isolation of Next-Generation Gene Therapy Vectors through Engineering, Barcoding, and Screening of Adeno-Associated Virus (AAV) Capsid Variants.
K. Rapti, Olena Maiakovska, Jonas P. Becker, Joanna Szumska +7 more
2022Journal of Visualized Experiments3 citations
Semantic Scholar
Novel Approaches to Deliver Molecular Therapeutics in Cardiac Disease Using Adeno-Associated Virus Vectors
K. Rapti, R. Hajjar, T. Weber
20123 citations
Semantic Scholar
A universal protocol for isolating retinal ON bipolar cells across species via fluorescence-activated cell sorting
Elisa Murenu, M. Pavlou, L. Richter, K. Rapti +9 more
2021Molecular Therapy: Methods & Clinical Development2 citations Open access
Semantic Scholar
Corrigendum to “Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy” [Biochim. Biophys. Acta 1853/11 (2015) 2870–2884]
M. Ramos-Kuri, K. Rapti, Hind Mehel, Shi-Hong Zhang +10 more
20161 citations Open access
Semantic Scholar
Multimodality Imaging of Chronic Ischemia
K. Ishikawa, D. Ladage, K. Rapti, L. Fernández-Friera +5 more
2010Cardiology Research and Practice1 citations Open access
Semantic Scholar
αB-Crystallin and HSP25 mediate protection of the desmin null myocardium
E. Soumaka, K. Rapti, A. Diokmetzidou, D. Milner +2 more
20081 citations
Semantic Scholar
Study design and rationale of Boxed-Breathing-Heart: a translational ex vivo study evaluating virus-mediated gene delivery for gene therapy in normothermic machine-perfused human hearts
I. Branzei, A. Amr, K. Rapti, L. Schraft +18 more
2026medRxiv0 citations Open access
Semantic Scholar
Structural remodeling triggers functional maturation in human iPSC-derived cardiomyocytes
F. Kermani, E. Lemma, K. Rapti, D. Grimm +3 more
2022Journal of Molecular and Cellular Cardiology0 citations
Semantic Scholar
Abstract P1-17-08: Abemaciclib and endocrine therapy for hormone receptor-positive, HER2-negative advanced breast cancer: A real-world UK multicentre experience
N. Battisti, L. Morrison, T. Nash, N. Senthivel +36 more
2022Cancer Research0 citations
Semantic Scholar
Neoadjuvant endocrine treatment and clinical outcome in ER positive breast cancer – a single UK cancer centre experience
S. Benafif, K. Rapti, C. Nattress, M. Akay +5 more
20200 citations
Semantic Scholar
AAV-mediated cardiac gene transfer of wild-type desmin in mouse models for recessive desminopathies
T. Ruppert, M. Heckmann, K. Rapti, D. Schultheis +7 more
2020Gene Therapy0 citations Open access
Semantic Scholar
P1616L-2-hydroxyglutarate dehydrogenase (L2HGDH) is a novel target for heart failure due to pressure overload
A. Remes, L. Ding, B. Kamlage, U. Rennefahrt +9 more
2019European Heart Journal0 citations
Semantic Scholar
P4776Targeting metabolic remodeling in a murine heart failure model by AAV-mediated over-expression of organic cation/carnitine transporter 2 (OCTN2)
L. Ding, M. Heckmann, D. Schwab, T. Ruf +8 more
2018European Heart Journal0 citations
Semantic Scholar
P3760Comprehensive fingerprints of plasma, heart, liver, and muscle tissue disclose systemic metabolic alterations in cardiac hypertrophy and heart failure
O. Mueller, M. Heckmann, L. Ding, K. Rapti +9 more
2018European Heart Journal0 citations Open access
Semantic Scholar
197Inhibition of TASK-1 by gene therapy and pharmacological compounds suppresses atrial fibrillation in a large animal model
Carolina Witchmichen Penteado Schmidt, F. Wiedmann, C. Beyersdorf, Zhi-Han Zhao +10 more
2018European Heart Journal0 citations
Semantic Scholar
Tilemann Model of Heart Failure Gene Transfer Improves Cardiac Function in a Large-Animal SUMO-1
L. Tilemann, Ahyoung Lee, K. Ishikawa, J. Aguero +6 more
20130 citations
Semantic Scholar

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R. Hajjar — researcher profile on SciRah
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