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C. Schmidt · SciRah

Researcher profile · Semantic Scholar

C. Schmidt

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C. Schmidt — researcher profile on SciRah

h-index: 28
Works: 82
Citations: 1,951

Most-cited papers

Vascular Health and Risk Management Dovepress the Pathology and Treatment of Cardiac Arrhythmias: Focus on Atrial Fibrillation
C. Schmidt, Jana Kisselbach, P. Schweizer, Hugo A. Katus +1 more
169 citations
Semantic Scholar
Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation
C. Schmidt, F. Wiedmann, N. Voigt, Xiaobo Zhou +18 more
2015Circulation150 citations Open access
Semantic Scholar
SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
Adam Leitman Bailey, O. Dmytrenko, Lina Greenberg, Andrea L. Bredemeyer +25 more
2021JACC: Basic to Translational Science130 citations Open access
Semantic Scholar
Inverse remodelling of K2P3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation: implications for patient-specific antiarrhythmic drug therapy
C. Schmidt, F. Wiedmann, Xiaobo Zhou, J. Heijman +18 more
2017European Heart Journal93 citations Open access
Semantic Scholar
Piezo1 and BKCa channels in human atrial fibroblasts: interplay and remodelling in atrial fibrillation
D. Jakob, A. Klesen, B. Allegrini, Elisa Darkow +16 more
2021bioRxiv63 citations
Semantic Scholar
Altered atrial cytosolic calcium handling contributes to the development of postoperative atrial fibrillation
Funsho E. Fakuade, Vanessa Steckmeister, F. Seibertz, Judith Gronwald +18 more
2020Cardiovascular Research60 citations Open access
Semantic Scholar
Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels
C. Schmidt, F. Wiedmann, P. Schweizer, R. Becker +2 more
2012Naunyn-Schmiedeberg's Archives of Pharmacology50 citations
Semantic Scholar
The pathology and treatment of cardiac arrhythmias: focus on atrial fibrillation
C. Schmidt, Jana Kisselbach, P. Schweizer, Hugo A. Katus +1 more
201149 citations
Semantic Scholar
Treatment of atrial fibrillation with doxapram: TASK-1 potassium channel inhibition as a novel pharmacological strategy.
F. Wiedmann, C. Beyersdorf, Xiaobo Zhou, M. Kraft +23 more
2021Cardiovascular Research47 citations Open access
Semantic Scholar
Ion Channel Dysfunctions in Dilated Cardiomyopathy in Limb-Girdle Muscular Dystrophy
I. El-Battrawy, Zhi-Han Zhao, H. Lan, Xin Li +24 more
2018Circulation Genomic and Precision Medicine47 citations Open access
Semantic Scholar
SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
Adam Leitman Bailey, O. Dmytrenko, Lina Greenberg, Andrea L. Bredemeyer +25 more
2020bioRxiv46 citations Open access
Semantic Scholar
Stretch-activated two-pore-domain (K2P) potassium channels in the heart: Focus on atrial fibrillation and heart failure.
C. Schmidt, F. Wiedmann, S. Kallenberger, Antonius Ratte +12 more
2017Progress in Biophysics and Molecular Biology46 citations
Semantic Scholar
Cloning, functional characterization, and remodeling of K2P3.1 (TASK-1) potassium channels in a porcine model of atrial fibrillation and heart failure.
C. Schmidt, F. Wiedmann, C. Langer, Frank Tristram +6 more
2014Heart Rhythm44 citations
Semantic Scholar
Acute antiarrhythmic effects of SGLT2 inhibitors–dapagliflozin lowers the excitability of atrial cardiomyocytes
A. Paasche, F. Wiedmann, M. Kraft, F. Seibertz +15 more
2024Basic Research in Cardiology43 citations Open access
Semantic Scholar
Two-Pore-Domain Potassium (K2P-) Channels: Cardiac Expression Patterns and Disease-Specific Remodelling Processes
F. Wiedmann, N. Frey, C. Schmidt
2021Cells43 citations Open access
Semantic Scholar
Cardiac expression and atrial fibrillation-associated remodeling of K₂p2.1 (TREK-1) K⁺ channels in a porcine model.
C. Schmidt, F. Wiedmann, Frank Tristram, Priya Anand +5 more
2014Life Science43 citations
Semantic Scholar
Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism
N. Grammatika-Pavlidou, Shokoufeh Dobrev, K. Beneke, Franziska Reinhardt +13 more
2023European Heart Journal42 citations Open access
Semantic Scholar
Axial Tubule Junctions Activate Atrial Ca2+ Release Across Species
S. Brandenburg, J. Pawlowitz, Funsho E. Fakuade, D. Kownatzki-Danger +13 more
2018Frontiers in Physiology40 citations Open access
Semantic Scholar
Small Conductance Ca2 +-Activated K+ (SK) Channel mRNA Expression in Human Atrial and Ventricular Tissue: Comparison Between Donor, Atrial Fibrillation and Heart Failure Tissue
Elisa Darkow, Thong T. Nguyen, M. Stolina, F. Kari +7 more
2021Frontiers in Physiology39 citations Open access
Semantic Scholar
Therapeutic targeting of two-pore-domain potassium (K(2P)) channels in the cardiovascular system.
F. Wiedmann, C. Schmidt, P. Lugenbiel, Ingo Staudacher +5 more
2016Clinical science39 citations
Semantic Scholar
Inhibition of cardiac two-pore-domain K+ (K2P) channels--an emerging antiarrhythmic concept.
C. Schmidt, F. Wiedmann, P. Schweizer, H. Katus +1 more
2014European Journal of Pharmacology39 citations
Semantic Scholar
Genetic Ablation of TASK-1 (Tandem of P Domains in a Weak Inward Rectifying K+ Channel-Related Acid-Sensitive K+ Channel-1) (K2P3.1) K+ Channels Suppresses Atrial Fibrillation and Prevents Electrical Remodeling.
C. Schmidt, F. Wiedmann, C. Beyersdorf, Zhi-Han Zhao +17 more
2019Circulation: Arrhythmia and Electrophysiology38 citations Open access
Semantic Scholar
Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation
E. Glasscock, N. Voigt, M. McCauley, Qiang Sun +10 more
2015Basic Research in Cardiology38 citations Open access
Semantic Scholar
Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system.
F. Wiedmann, S. Rinné, B. Donner, Niels Decher +2 more
2020Progress in Biophysics and Molecular Biology37 citations
Semantic Scholar
Atrial fibrillation and heart failure-associated remodeling of two-pore-domain potassium (K2P) channels in murine disease models: focus on TASK-1
F. Wiedmann, J. Schulte, B. Gomes, M. Zafeiriou +9 more
2018Basic Research in Cardiology37 citations
Semantic Scholar
Anti-KCNQ1 K⁺ channel autoantibodies increase IKs current and are associated with QT interval shortening in dilated cardiomyopathy.
Jin Li, C. Seyler, F. Wiedmann, C. Schmidt +4 more
2013Cardiovascular Research36 citations Open access
Semantic Scholar
Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K(+) (K2 ₂p) channels.
C. Schmidt, F. Wiedmann, P. Schweizer, R. Becker +2 more
2013European Journal of Pharmacology34 citations
Semantic Scholar
MicroRNAs Regulate TASK‐1 and Are Linked to Myocardial Dilatation in Atrial Fibrillation
F. Wiedmann, M. Kraft, S. Kallenberger, A. Büscher +10 more
2022Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease32 citations Open access
Semantic Scholar
Pharmacologic TWIK‐Related Acid‐Sensitive K+ Channel (TASK‐1) Potassium Channel Inhibitor A293 Facilitates Acute Cardioversion of Paroxysmal Atrial Fibrillation in a Porcine Large Animal Model
F. Wiedmann, C. Beyersdorf, Xiaobo Zhou, A. Büscher +13 more
2020Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease28 citations Open access
Semantic Scholar
Antiarrhythmic Properties of Ranolazine: Inhibition of Atrial Fibrillation Associated TASK-1 Potassium Channels
Antonius Ratte, F. Wiedmann, M. Kraft, H. Katus +1 more
2019Frontiers in Pharmacology26 citations Open access
Semantic Scholar
Upregulation of K 2 P 3 . 1 K + Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation
C. Schmidt, F. Wiedmann, N. Voigt, Xiaobo Zhou +18 more
201526 citations
Semantic Scholar
Current Drug Treatment Strategies for Atrial Fibrillation and TASK-1 Inhibition as an Emerging Novel Therapy Option
M. Kraft, A. Büscher, F. Wiedmann, Y. L’hoste +4 more
2021Frontiers in Pharmacology25 citations Open access
Semantic Scholar
The Experimental TASK-1 Potassium Channel Inhibitor A293 Can Be Employed for Rhythm Control of Persistent Atrial Fibrillation in a Translational Large Animal Model
F. Wiedmann, C. Beyersdorf, Xiaobo Zhou, M. Kraft +7 more
2021Frontiers in Physiology24 citations Open access
Semantic Scholar
Worldwide survey on implantation of and outcomes for conduction system pacing with His bundle and left bundle branch area pacing leads
A. Perino, Paul J. Wang, M. Lloyd, F. Zanon +88 more
2023Journal of interventional cardiac electrophysiology23 citations Open access
Semantic Scholar
Functional characterization of zebrafish K2P18.1 (TRESK) two-pore-domain K+ channels
A. Rahm, F. Wiedmann, J. Gierten, C. Schmidt +4 more
2013Naunyn-Schmiedeberg's Archives of Pharmacology23 citations
Semantic Scholar
Identification of the A293 (AVE1231) Binding Site in the Cardiac Two-Pore-Domain Potassium Channel TASK-1: a Common Low Affinity Antiarrhythmic Drug Binding Site.
F. Wiedmann, Aytuğ K. Kiper, M. Bedoya, Antonius Ratte +9 more
2019Cellular Physiology and Biochemistry21 citations Open access
Semantic Scholar
Distress-Mediated Remodeling of Cardiac Connexin-43 in a Novel Cell Model for Arrhythmogenic Heart Diseases
C. Wahl, C. Schmidt, M. Hecker, N. Ullrich
2022International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Mechanisms of zolpidem‐induced long QT syndrome: acute inhibition of recombinant hERG K+ channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells
J. Jehle, E. Ficker, X. Wan, I. Deschênes +8 more
2013British Journal of Pharmacology18 citations Open access
Semantic Scholar
Effects of oral valganciclovir prophylaxis for cytomegalovirus infection in heart transplant patients
A. Doesch, J. Repp, Nina P. Hofmann, C. Erbel +9 more
2012Drug Design, Development and Therapy14 citations Open access
Semantic Scholar
Novel drug therapies for atrial fibrillation
F. Wiedmann, C. Schmidt
2024Nature Reviews Cardiology13 citations
Semantic Scholar
New Targets for Old Drugs: Cardiac Glycosides Inhibit Atrial-Specific K2P3.1 (TASK-1) Channels
C. Schmidt, F. Wiedmann, Anne-Rike Gaubatz, Antonius Ratte +2 more
2018Journal of Pharmacology and Experimental Therapeutics13 citations Open access
Semantic Scholar
Voltage-gated and stretch-activated potassium channels in the human heart
C. Schmidt, R. Peyronnet
2018Herzschrittmachertherapie & Elektrophysiologie12 citations
Semantic Scholar
Reduced Na+ Current in Native Cardiomyocytes of a Brugada Syndrome Patient Associated With &bgr;-2-Syntrophin Mutation
C. Schmidt, F. Wiedmann, I. El-Battrawy, Markus Fritz +11 more
2018Circulation Genomic and Precision Medicine11 citations
Semantic Scholar
N-glycosylation–dependent regulation of hK2P17.1 currents
F. Wiedmann, D. Schlund, N. Voigt, Antonius Ratte +3 more
2019Molecular Biology of the Cell8 citations Open access
Semantic Scholar
Single beta-blocker or combined amiodarone therapy in implantable cardioverter-defibrillator and cardiac resynchronization therapy defibrillator patients - insights from the German DEVICE-registry.
F. Wiedmann, H. Ince, C. Stellbrink, T. Kleemann +11 more
2022Heart Rhythm7 citations
Semantic Scholar
Ligand-activated RXFP1 gene therapy ameliorates pressure overload-induced cardiac dysfunction.
N. Sasipong, P. Schlegel, J. Wingert, C. Lederer +9 more
2021Molecular Therapy7 citations Open access
Semantic Scholar
Prospective multicentric validation of a novel prediction model for paroxysmal atrial fibrillation
C. Schmidt, S. Benda, P. Kraft, F. Wiedmann +8 more
2020Clinical Research in Cardiology7 citations Open access
Semantic Scholar
A Simple, Non-Invasive Score to Predict Paroxysmal Atrial Fibrillation
S. Kallenberger, C. Schmid, F. Wiedmann, D. Mereles +3 more
2016PLoS ONE7 citations Open access
Semantic Scholar
Stress-Kinase Regulation of TASK-1 and TASK-3
S. Rinné, Aytuğ K. Kiper, C. Schmidt, Beatriz Ortiz-Bonnin +3 more
2017Cellular Physiology and Biochemistry5 citations Open access
Semantic Scholar
Response to Letter Regarding Article, "Upregulation of K2P3.1 K+ Current Causes Action Potential Shortening in Patients With Chronic Atrial Fibrillation".
C. Schmidt, F. Wiedmann, N. Voigt, Xiaobo Zhou +18 more
2016Circulation5 citations Open access
Semantic Scholar

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