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B. Bernardo · SciRah

Researcher profile · Semantic Scholar

B. Bernardo

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B. Bernardo — researcher profile on SciRah

h-index: 30
Works: 68
Citations: 5,012

Most-cited papers

Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies.
B. Bernardo, K. Weeks, L. Pretorius, J. McMullen
2010Pharmacology and Therapeutics884 citations Open access
Semantic Scholar
Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets
Y. Tham, B. Bernardo, J. Ooi, K. Weeks +1 more
2015Archives of Toxicology650 citations Open access
Semantic Scholar
Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways.
K. Huynh, B. Bernardo, J. McMullen, R. Ritchie
2014Pharmacology and Therapeutics547 citations Open access
Semantic Scholar
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function
B. Bernardo, Xiao-Ming Gao, C. E. Winbanks, E. J. H. Boey +8 more
2012Proceedings of the National Academy of Sciences of the United States of America428 citations Open access
Semantic Scholar
miRNA therapeutics: a new class of drugs with potential therapeutic applications in the heart.
B. Bernardo, J. Ooi, Ruby C. Y. Lin, J. McMullen
2015Future Medicinal Chemistry225 citations Open access
Semantic Scholar
The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass
C. E. Winbanks, Justin L. Chen, H. Qian, Yingying Liu +11 more
2013Journal of Cell Biology221 citations Open access
Semantic Scholar
PI3K(p110&agr;) Protects Against Myocardial Infarction-Induced Heart Failure: Identification of PI3K-Regulated miRNA and mRNA
Ruby C. Y. Lin, K. Weeks, Xiao-Ming Gao, Rohan Williams +14 more
2010Arteriosclerosis, Thrombosis and Vascular Biology178 citations
Semantic Scholar
Understanding Key Mechanisms of Exercise-Induced Cardiac Protection to Mitigate Disease: Current Knowledge and Emerging Concepts.
B. Bernardo, J. Ooi, K. Weeks, Natalie L. Patterson +1 more
2018Physiological Reviews143 citations
Semantic Scholar
The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice
G. Sapra, Y. Tham, Nelly Cemerlang, A. Matsumoto +16 more
2014Nature Communications139 citations Open access
Semantic Scholar
Phosphoinositide 3-Kinase p110&agr; Is a Master Regulator of Exercise-Induced Cardioprotection and PI3K Gene Therapy Rescues Cardiac Dysfunction
K. Weeks, Xiao-Ming Gao, Xiao-Jun Du, E. J. H. Boey +13 more
2012Circulation: Heart Failure138 citations Open access
Semantic Scholar
A microRNA guide for clinicians and basic scientists: background and experimental techniques.
B. Bernardo, F. Charchar, Ruby C. Y. Lin, J. McMullen
2012Heart, Lung and Circulation105 citations Open access
Semantic Scholar
Changes in the Chondrocyte and Extracellular Matrix Proteome during Post-natal Mouse Cartilage Development*
Richardf . Wilson, Emma L. Norris, B. Brachvogel, C. Angelucci +7 more
2011Molecular & Cellular Proteomics103 citations Open access
Semantic Scholar
Cartilage Intermediate Layer Protein 2 (CILP-2) Is Expressed in Articular and Meniscal Cartilage and Down-regulated in Experimental Osteoarthritis*
B. Bernardo, D. Belluoccio, L. Rowley, C. Little +2 more
2011Journal of Biological Chemistry97 citations Open access
Semantic Scholar
The IGF1-PI3K-Akt Signaling Pathway in Mediating Exercise-Induced Cardiac Hypertrophy and Protection.
K. Weeks, B. Bernardo, J. Ooi, Natalie L. Patterson +1 more
2017Advances in Experimental Medicine and Biology93 citations Open access
Semantic Scholar
Enhanced phosphoinositide 3-kinase(p110α) activity prevents diabetes-induced cardiomyopathy and superoxide generation in a mouse model of diabetes
R. Ritchie, J. Love, K. Huynh, B. Bernardo +10 more
2012Diabetologia90 citations Open access
Semantic Scholar
Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice
C. E. Winbanks, K. Murphy, B. Bernardo, H. Qian +13 more
2016Science Translational Medicine87 citations
Semantic Scholar
Therapeutic silencing of miR‐652 restores heart function and attenuates adverse remodeling in a setting of established pathological hypertrophy
B. Bernardo, Sally S. Nguyen, C. E. Winbanks, Xiao-Ming Gao +11 more
2014The FASEB Journal78 citations Open access
Semantic Scholar
Silencing of miR-34a Attenuates Cardiac Dysfunction in a Setting of Moderate, but Not Severe, Hypertrophic Cardiomyopathy
B. Bernardo, Xiao-Ming Gao, Y. Tham, H. Kiriazis +9 more
2014PLoS ONE77 citations Open access
Semantic Scholar
The therapeutic potential of miRNAs regulated in settings of physiological cardiac hypertrophy.
J. Ooi, B. Bernardo, J. McMullen
2014Future Medicinal Chemistry70 citations Open access
Semantic Scholar
Lipidomic Profiles of the Heart and Circulation in Response to Exercise versus Cardiac Pathology: A Resource of Potential Biomarkers and Drug Targets.
Y. Tham, B. Bernardo, K. Huynh, J. Ooi +5 more
2018Cell Reports53 citations Open access
Semantic Scholar
Identification of miR-34 regulatory networks in settings of disease and antimiR-therapy: Implications for treating cardiac pathology and other diseases
J. Ooi, B. Bernardo, S. Singla, Natalie L. Patterson +2 more
2017RNA Biology52 citations Open access
Semantic Scholar
Inhibition of miR-154 Protects Against Cardiac Dysfunction and Fibrosis in a Mouse Model of Pressure Overload
B. Bernardo, Sally S. Nguyen, Xiao-Ming Gao, Y. Tham +8 more
2016Scientific Reports51 citations Open access
Semantic Scholar
Sex differences in response to miRNA‐34a therapy in mouse models of cardiac disease: identification of sex‐, disease‐ and treatment‐regulated miRNAs
B. Bernardo, J. Ooi, A. Matsumoto, Y. Tham +7 more
2016Journal of Physiology48 citations Open access
Semantic Scholar
Adeno-Associated Virus Gene Therapy: Translational Progress and Future Prospects in the Treatment of Heart Failure.
S. Bass-Stringer, B. Bernardo, C. May, Colleen J. Thomas +2 more
2018Heart, Lung and Circulation39 citations Open access
Semantic Scholar
Molecular Aspects of Exercise-induced Cardiac Remodeling.
B. Bernardo, J. McMullen
2016Cardiology Clinics34 citations Open access
Semantic Scholar
Phosphoinositide 3-Kinase (PI3K(p110α)) Directly Regulates Key Components of the Z-disc and Cardiac Structure*
A. Waardenberg, B. Bernardo, D. Ng, P. Shepherd +7 more
2011Journal of Biological Chemistry34 citations Open access
Semantic Scholar
β‐Adrenergic Stimulation Induces Histone Deacetylase 5 (HDAC5) Nuclear Accumulation in Cardiomyocytes by B55α‐PP2A‐Mediated Dephosphorylation
K. Weeks, A. Ranieri, A. Karaś, B. Bernardo +4 more
2017Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease33 citations Open access
Semantic Scholar
FoxO1 is required for physiological cardiac hypertrophy induced by exercise but not by constitutively active PI3K.
K. Weeks, Y. Tham, S. Yildiz, Yonali Alexander +10 more
2021American Journal of Physiology. Heart and Circulatory Physiology32 citations Open access
Semantic Scholar
Generation of MicroRNA-34 Sponges and Tough Decoys for the Heart: Developments and Challenges
B. Bernardo, P. Gregorevic, R. Ritchie, J. McMullen
2018Frontiers in Pharmacology31 citations Open access
Semantic Scholar
A microarray approach for comparative expression profiling of the discrete maturation zones of mouse growth plate cartilage.
D. Belluoccio, B. Bernardo, L. Rowley, J. Bateman
2008Biochimica et Biophysica Acta31 citations
Semantic Scholar
Estrogen receptor alpha deficiency in cardiomyocytes reprograms the heart-derived extracellular vesicle proteome and induces obesity in female mice
Y. Tham, B. Bernardo, B. Claridge, Gunes S. Yildiz +24 more
2023Nature Cardiovascular Research30 citations Open access
Semantic Scholar
MicroRNAs differentially regulated in cardiac and skeletal muscle in health and disease: Potential drug targets?
C. E. Winbanks, J. Ooi, Sally S. Nguyen, J. McMullen +1 more
2014Clinical and Experimental Pharmacology and Physiology27 citations Open access
Semantic Scholar
In Vivo Inhibition of miR-34a Modestly Limits Cardiac Enlargement and Fibrosis in a Mouse Model with Established Type 1 Diabetes-Induced Cardiomyopathy, but Does Not Improve Diastolic Function
B. Bernardo, Gunes S. Yildiz, H. Kiriazis, C. Harmawan +3 more
2022Cells21 citations Open access
Semantic Scholar
Non-coding RNAs regulating cardiac muscle mass.
G. Wadley, S. Lamon, S. E. Alexander, J. McMullen +1 more
2019Journal of applied physiology21 citations Open access
Semantic Scholar
Long-Term Overexpression of Hsp70 Does Not Protect against Cardiac Dysfunction and Adverse Remodeling in a MURC Transgenic Mouse Model with Chronic Heart Failure and Atrial Fibrillation
B. Bernardo, G. Sapra, Natalie L. Patterson, Nelly Cemerlang +4 more
2015PLoS ONE18 citations Open access
Semantic Scholar
HSP70: therapeutic potential in acute and chronic cardiac disease settings.
B. Bernardo, K. Weeks, Natalie L. Patterson, J. McMullen
2016Future Medicinal Chemistry17 citations Open access
Semantic Scholar
Gene delivery of medium chain acyl-coenzyme A dehydrogenase induces physiological cardiac hypertrophy and protects against pathological remodelling.
B. Bernardo, K. Weeks, T. Pongsukwechkul, Xiao-Ming Gao +9 more
2018Clinical science16 citations Open access
Semantic Scholar
From Bench to Bedside: New Approaches to Therapeutic Discovery for Heart Failure.
B. Bernardo, B. Blaxall
2016Heart, Lung and Circulation16 citations Open access
Semantic Scholar
A gene therapy targeting medium-chain acyl-CoA dehydrogenase (MCAD) did not protect against diabetes-induced cardiac pathology
K. Weeks, H. Kiriazis, G. Wadley, Emma I. Masterman +11 more
2023Journal of molecular medicine10 citations Open access
Semantic Scholar
The yin and yang of adaptive and maladaptive processes in heart failure
B. Bernardo, J. Ooi, J. McMullen
201210 citations Open access
Semantic Scholar
Inhibition of miR-29 protects against cardiac hypertrophy and fibrosis: new insight for the role of miR-29 in the heart
J. McMullen, B. Bernardo
20188 citations Open access
Semantic Scholar
Therapeutic potential of targeting microRNAs to regulate cardiac fibrosis: miR-433 a new fibrotic player.
J. Ooi, B. Bernardo, J. McMullen
2016Annals of Translational Medicine7 citations Open access
Semantic Scholar
Old Drug, New Trick: Tilorone, a Broad-Spectrum Antiviral Drug as a Potential Anti-Fibrotic Therapeutic for the Diseased Heart
D. Horlock, D. Kaye, C. E. Winbanks, Xiao-Ming Gao +5 more
2021Pharmaceuticals6 citations Open access
Semantic Scholar
Translational Potential of Non-coding RNAs for Cardiovascular Disease.
J. Ooi, B. Bernardo
2020Advances in Experimental Medicine and Biology5 citations Open access
Semantic Scholar
143Gene Delivery of Medium Chain Acyl-coenzyme A Dehydrogenase (MCAD) Induces Physiological Cardiac Hypertrophy and Protects Against Pathological Remodelling
B. Bernardo, K. Weeks, T. Pongsukwechkul, Xiao-Ming Gao +5 more
20174 citations Open access
Semantic Scholar
Generation and evaluation of a novel PI3K-targeting gene therapy in the failing mouse heart and healthy sheep heart
S. Bass-Stringer, Daniel G. Donner, Clive N. May, Aya Matsumoto +12 more
2025Journal of Molecular and Cellular Cardiology Plus2 citations Open access
Semantic Scholar
Estrogen receptor α deficiency in cardiac myocytes reprograms heart-derived extracellular vesicle proteome and induces obesity in female mice
Y. Tham, B. Bernardo, B. Claridge, Liesel Woon +15 more
2022Journal of Molecular and Cellular Cardiology1 citations
Semantic Scholar
Identification of novel cardioprotective miRNAs and mRNAs regulated by miR-34
J. Ooi, B. Bernardo, Ruby C. Y. Lin, J. McMullen
20151 citations Open access
Semantic Scholar
The Therapeutic Potential of microRNA-652 for the Treatment of Heart Failure
B. Bernardo, Xiao-Ming Gao, Y. Tham, Ruby C. Y. Lin +3 more
20131 citations
Semantic Scholar
Generation and Characterisation of Novel PI3K-Based Gene Therapies for the Treatment of Heart Failure
S. Bass-Stringer, D. Donner, H. Kiriazis, A. Brown +6 more
2021Heart, Lung and Circulation0 citations
Semantic Scholar

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J. McMullen×45
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H. Kiriazis×22
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P. Gregorevic×13

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C. E. Winbanks×7

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