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P. Guedat · SciRah

Researcher profile · Semantic Scholar

P. Guedat

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P. Guedat — researcher profile on SciRah

h-index: 12
Works: 43
Citations: 1,153

Most-cited papers

Gemini surfactants: new synthetic vectors for gene transfection.
A. Kirby, P. Camilleri, J. Engberts, M. C. Feiters +12 more
2003Angewandte Chemie349 citations
Semantic Scholar
Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells
F. Colland, E. Formstecher, X. Jacq, Céline Reverdy +15 more
2009Molecular Cancer Therapeutics304 citations Open access
Semantic Scholar
Synthesis and Biological Evaluation of 9‐Oxo‐9H‐indeno[1,2‐b]pyrazine‐2,3‐dicarbonitrile Analogues as Potential Inhibitors of Deubiquitinating Enzymes
M. Colombo, S. Vallese, I. Peretto, X. Jacq +3 more
2010ChemMedChem114 citations
Semantic Scholar
Patented small molecule inhibitors in the ubiquitin proteasome system
P. Guedat, F. Colland
2007BMC Biochemistry83 citations Open access
Semantic Scholar
Control of the Unfolded Protein Response in Health and Disease
Dimitrios Doultsinos, T. Avril, S. Lhomond, N. Dejeans +2 more
2017SLAS discovery : advancing life sciences R & D63 citations Open access
Semantic Scholar
Novel spermine-based cationic gemini surfactants for gene delivery.
G. Ronsin, Christèle Perrin, P. Guedat, AndreasE. Kremer +2 more
2001Chemical Communications56 citations
Semantic Scholar
Treatment with IFB-088 Improves Neuropathy in CMT1A and CMT1B Mice
Yunhong Bai, Caroline Treins, Vera G. Volpi, C. Scapin +12 more
2021Molecular Neurobiology33 citations Open access
Semantic Scholar
Pharmacological modulation of the ER stress response ameliorates oculopharyngeal muscular dystrophy.
A. Malerba, F. Roth, P. Harish, J. Dhiab +15 more
2019Human Molecular Genetics29 citations Open access
Semantic Scholar
Small-molecule inhibitor of USP 7 / HAUSP ubiquitin protease stabilizes and activates p 53 in cells
F. Colland, E. Formstecher, X. Jacq, Céline Reverdy +15 more
200929 citations
Semantic Scholar
A conformationally restricted cyclic phosphate analogue of inositol trisphosphate: synthesis and physicochemical properties
A. M. Riley, P. Guedat, G. Schlewer, B. Spiess +1 more
199826 citations
Semantic Scholar
Inframolecular acid–base studies of the tris and tetrakis myo-inositol phosphates including the 1,2,3-trisphosphate motif
Hélène Dozol, C. Blum-Held, P. Guedat, C. Maechling +3 more
200214 citations Open access
Semantic Scholar
Investigation of the inframolecular acid-base properties of D-myo-inositol 1,3,4,5-tetrakisphosphate and DL-myo-inositol 1,2,4,5-tetrakisphosphate
P. Guedat, G. Schlewer, E. Krempp, A. M. Riley +2 more
199712 citations
Semantic Scholar
Synthesis of (±) 1,2-dideoxy-1,2-diamino-myo-inositol
P. Guedat, B. Spiess, G. Schlewer
199411 citations
Semantic Scholar
Inositol Phosphates: Inframolecular Physico-Chemical Studies: Correlation with Binding Properties
G. Schlewer, P. Guedat, Stéphanie Ballereau, L. Schmitt +1 more
19988 citations
Semantic Scholar
Synthesis of (±)-4-deoxy-4-fluoro-myo-inositol
Stéphanie Ballereau, P. Guedat, B. Spiess, N. Rehnberg +1 more
19958 citations
Semantic Scholar
The small compound Icerguastat reduces muscle defects in oculopharyngeal muscular dystrophy through the PERK pathway of the unfolded protein response
Rima Naït-Saïdi, A. Chartier, E. Abgueguen, P. Guedat +1 more
2023Open Biology5 citations Open access
Semantic Scholar
A Conformationally Restricted Cyclic Phosphate Analogue of Inositol Trisphosphate: Synthesis and Physicochemical Properties.
A. M. Riley, P. Guedat, G. Schlewer, B. Spiess +1 more
19985 citations
Semantic Scholar
Rapid synthesis and properties of (±)-6-Deoxy-6-fluoro-myo-inositol-1,4,5-tris(phosphate) an analogue of myo-inositol-1,4,5-tris(phosphate)
P. Guedat, M. Poitras, B. Spiess, G. Guillemette +1 more
19963 citations
Semantic Scholar
Synthesis of α-Trinositol Analogues Derived from D-(-)-Quinic Acid as Affinity Probe Precursors
P. Guedat, N. Rehnberg, B. Spiess, G. Schlewer
19971 citations
Semantic Scholar
A Rat Model of Clinically Relevant Extracorporeal Circulation Develops Early Organ Dysfunctions
A. Persello, F. Souab, T. Dupas, V. Aillerie +11 more
2023International Journal of Molecular Sciences0 citations Open access
Semantic Scholar
Integrated stress response activation after recovery of cardiopulmonary bypass in rats
A. Persello, V. Aillerie, A. Erraud, P. Miniou +6 more
20200 citations Open access
Semantic Scholar
Effect of cardiopulmonary bypass on a stress response pathway in a recovery rat's model
A. Persello, A. Erraud, V. Aillerie, P. Miniou +6 more
2019Archives of Cardiovascular Diseases Supplements0 citations Open access
Semantic Scholar
Guanabenz treatment improves Oculopharyngeal muscular dystrophy phenotype
A. Malerba, F. Roth, P. Harish, J. Dhiab +15 more
2018bioRxiv0 citations Open access
Semantic Scholar
Benzylidenguanidinderivativer and therapeutic use for the treatment of diseases associated with improper protein folding
P. Guedat, A. Bertolotti
20140 citations
Semantic Scholar
Sa1079 CVVS-732: A Conformational Modulator of NS5B Polymerase Acting a Potent HCV Inhibitor
P. Guedat, I. Valarché, M. Lahmar, A. Berecibar +11 more
20120 citations Open access
Semantic Scholar
1181 VLS-732: A NEW ANTI-HCV COMPOUND ACTING AS AN NS5B POLYMERASE CONFORMATIONAL MODULATOR
P. Guedat, I. Valarché, M. Lahmar, A. Berecibar +11 more
20120 citations
Semantic Scholar
1216 HIGHLY POTENT HCV NS5B INHIBITOR WITH ORIGINAL MECHANISM OF ACTION IDENTIFIED WITH THE 3D-SCREEN TECHNOLOGY
M. Lahmar, A. Berecibar, I. Valarché, Aurélie Martin +6 more
20110 citations Open access
Semantic Scholar
The 3D-Screen Technology, an Innovative Cell-based Assay to Identify Modulators that Alter Target Protein Conformation: Example with HCV
I. Valarché, A. Berecibar, M. Lahmar, L. Batard +6 more
20110 citations
Semantic Scholar
Abstract 2642: Identification and characterization of selective inhibitors of ubiquitin specific protease 7
Céline Reverdy, S. Conrath, R. Lopez, Cécile Planquette +5 more
20100 citations
Semantic Scholar
Abstract B193: Identification of selective inhibitors of ubiquitin specific proteases
R. Lopez, V. Collura, Céline Reverdy, Cécile Planquette +5 more
20090 citations
Semantic Scholar
Patented Molecule Inhibitors in the UPS
P. Guedat
20070 citations
Semantic Scholar
Identification of cyano indenopyrazine derivatives as a novel series of potent ubiquitin-specific protease inhibitors
F. Colland, E. Formstecher, Cécile Planquette, Céline Reverdy +7 more
20070 citations
Semantic Scholar
345 POSTER Identification and characterization of small molecule inhibitors of ubiquitin-specific protease 8, a newly validated cancer target
F. Colland, V. Collura, E. Formstecher, X. Jacq +6 more
20060 citations
Semantic Scholar
Aroyl-o-piperidine derivatives for handling problems in connection with diabetes
P. Guedat, F. Collonges, O. Chevreuil, H. Dumas +6 more
20050 citations
Semantic Scholar
DIAZENIUMDIOLATE new compounds, their method of preparing them and therapeutic use
P. Guedat, C. Lardy, J. Nioche, Dangremont Valerie Guyard +1 more
20040 citations
Semantic Scholar
Derived structure has aroyl-O-piperidine, their processes of preparation, pharmaceutical compositions containing them and their therapeutic applications
P. Guedat, F. Collonges, O. Chevreuil, H. Dumas +6 more
20040 citations
Semantic Scholar
Thiazolylpiperidin derivatives as inhibitors mtp
P. Guedat, F. Collonges, H. Dumas, J. Ortholand +5 more
20040 citations
Semantic Scholar
Derivatives of thiazolylpiperidine, their processes of preparation and pharmaceutical compositions containing them
P. Guedat, F. Collonges, H. Dumas, J. Ortholand +5 more
20030 citations
Semantic Scholar
Derivatives of diphenylamine.
C. Lardy, P. Guedat, L. Caputo
20030 citations
Semantic Scholar
Synthesis of Thio Analogues of myo-Inositol-1-monophosphate, as Possible Inhibitors of myo-Inositol-1-monophosphatase.
N. Schnetz, P. Guedat, B. Spiess, G. Schlewer
19960 citations
Semantic Scholar
Synthesis of (.+-.)-4-Deoxy-4-fluoro-myo-inositol.
Stéphanie Ballereau, P. Guedat, B. Spiess, N. Rehnberg +1 more
19960 citations
Semantic Scholar
Synthesis of (.+-.)-1,2-Dideoxy-1,2-diamino-myo-inositol.
P. Guedat, B. Spiess, G. Schlewer
19950 citations
Semantic Scholar
31P N.M.R. and potentiometric investigation of the protonation and complexation properties of myo-inositol phosphates: Biological consequences.
I. Schmitt, K. Mernissi, P. Guedat, G. Schlewer +1 more
19930 citations
Semantic Scholar

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