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L. Lyytikäinen · SciRah

Researcher profile · Semantic Scholar

L. Lyytikäinen

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L. Lyytikäinen — researcher profile on SciRah

h-index: 79
Works: 328
Citations: 31K

Most-cited papers

The power of genetic diversity in genome-wide association studies of lipids
Sarah E. Graham, S. Clarke, Kuan-Han H. Wu, S. Kanoni +496 more
2021Nature826 citations Open access
Semantic Scholar
Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.
J. Hartiala, Yi Han, Qiong Jia, James R. Hilser +55 more
2021European Heart Journal229 citations Open access
Semantic Scholar
Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention
Zhe Wang, Andrew Emmerich, Nicolas J. Pillon, Timothy Moore +223 more
2022Nature Genetics195 citations Open access
Semantic Scholar
Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification
M. Kavousi, M. Bos, H. Barnes, C. L. Cardenas +85 more
2023Nature Genetics74 citations Open access
Semantic Scholar
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
S. Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka +496 more
2022Genome Biology59 citations Open access
Semantic Scholar
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways
William J. Young, N. Lahrouchi, A. Isaacs, T. Duong +162 more
2022Nature Communications53 citations Open access
Semantic Scholar
The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease
Marita Kalaoja, L. Corbin, Vanessa Y. Tan, A. Ahola-Olli +19 more
2021Obesity53 citations Open access
Semantic Scholar
C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis
Inhye Park, M. Goddard, J. Cole, Natacha Zanin +7 more
2022Nature Communications52 citations Open access
Semantic Scholar
Polygenic prediction of body mass index and obesity through the life course and across ancestries
R. Smit, K. Wade, Qin Hui, J. Arias +496 more
2025Nature Medicine51 citations Open access
Semantic Scholar
Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies
M. Gorski, H. Rasheed, A. Teumer, Laurent F. Thomas +172 more
2022Kidney International44 citations Open access
Semantic Scholar
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
S. Ramdas, Jonathan Judd, Sarah E. Graham, S. Kanoni +496 more
2022American Journal of Human Genetics36 citations Open access
Semantic Scholar
Genetic insights into resting heart rate and its role in cardiovascular disease
Y. J. van de Vegte, R. Eppinga, M. Yldau van der Ende, Y. Hagemeijer +188 more
2023Nature Communications34 citations Open access
Semantic Scholar
Prediction of Sudden Cardiac Death With Ultra-Short-Term Heart Rate Fluctuations.
J. Hernesniemi, Teemu Pukkila, Matti Molkkari, K. Nikus +5 more
2024JACC Clinical Electrophysiology28 citations Open access
Semantic Scholar
Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals
T. Winkler, Humaira Rasheed, A. Teumer, M. Gorski +310 more
2022Communications Biology28 citations Open access
Semantic Scholar
Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs
S. Marttila, Leena E. Viiri, Pashupati P. Mishra, Brigitte Kühnel +15 more
2021Clinical Epigenetics27 citations Open access
Semantic Scholar
The prevalence and prognostic significance of interatrial block in the general population
Tiia Istolahti, Antti Eranti, H. Huhtala, L. Lyytikäinen +8 more
2020Annals medicus27 citations Open access
Semantic Scholar
Long-term tracking and population characteristics of lipoprotein (a) in the Cardiovascular Risk in Young Finns Study.
O. Raitakari, Annukka M. Kivelä, K. Pahkala, S. Rovio +11 more
2022Atherosclerosis24 citations Open access
Semantic Scholar
The prognostic significance of T‐wave inversion according to ECG lead group during long‐term follow‐up in the general population
Tiia Istolahti, L. Lyytikäinen, H. Huhtala, T. Nieminen +8 more
2020Annals of Noninvasive Electrocardiology24 citations Open access
Semantic Scholar
Magical thinking in individuals with high polygenic risk for schizophrenia but no non-affective psychoses—a general population study
A. Saarinen, L. Lyytikäinen, J. Hietala, Henrik Dobewall +6 more
2022Molecular Psychiatry19 citations Open access
Semantic Scholar
Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health
S. Marttila, S. Rovio, Pashupati P. Mishra, I. Seppälä +11 more
2021Scientific Reports19 citations Open access
Semantic Scholar
Cohort Profile Update: Expanding the Cardiovascular Risk in Young Finns Study into a multigenerational cohort
K. Pahkala, S. Rovio, N. Kartiosuo, Kari Auranen +36 more
2024medRxiv16 citations Open access
Semantic Scholar
X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements
Markus Scholz, K. Horn, Janne Pott, M. Wuttke +155 more
2024Nature Communications15 citations Open access
Semantic Scholar
Author Correction: The power of genetic diversity in genome-wide association studies of lipids
Sarah E. Graham, S. Clarke, Kuan-Han H. Wu, S. Kanoni +496 more
2023Nature12 citations Open access
Semantic Scholar
Examining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts
J. Laaksonen, P. Mishra, I. Seppälä, L. Lyytikäinen +11 more
2021Scientific Reports10 citations Open access
Semantic Scholar
Assessment of plasma ceramides as predictor for subclinical atherosclerosis
Pashupati P. Mishra, B. Mishra, L. Lyytikäinen, M. Hilvo +7 more
2021Atherosclerosis Plus10 citations Open access
Semantic Scholar
Viridans Streptococcal Biofilm Evades Immune Detection and Contributes to Inflammation and Rupture of Atherosclerotic Plaques
P. J. Karhunen, T. Pessi, S. Hörkkö, V. Karhunen +16 more
2025Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease9 citations Open access
Semantic Scholar
Trans-eQTLs reveal the architecture of human gene regulatory networks
C.A. Robert Warmerdam, H. Westra, A. van der Graaf, M. Bonder +127 more
2026medRxiv8 citations Open access
Semantic Scholar
Impedance plethysmography-based method in the assessment of subclinical atherosclerosis.
Mira Haapala, L. Lyytikäinen, M. Peltokangas, Teemu Koivistoinen +8 more
2021Atherosclerosis8 citations Open access
Semantic Scholar
Accumulation of Lewy‐Related Pathology Starts in Middle Age: The Tampere Sudden Death Study
Eloise H. Kok, A. Paetau, M. Martiskainen, L. Lyytikäinen +3 more
2024Annals of Neurology7 citations Open access
Semantic Scholar
A large-scale genome-wide study of gene-sleep duration interactions for blood pressure in 811,405 individuals from diverse populations
P. Nagarajan, T. Winkler, Amy R. Bentley, Clint L. Miller +158 more
2025Molecular Psychiatry6 citations Open access
Semantic Scholar
Predicting long-term risk of sudden cardiac death with automatic computer-interpretations of electrocardiogram
Minna Järvensivu-Koivunen, Antti Kallonen, M. van Gils, L. Lyytikäinen +2 more
2024Frontiers in Cardiovascular Medicine6 citations Open access
Semantic Scholar
Polygenic risk for schizophrenia predicting social trajectories in a general population sample.
A. Saarinen, J. Hietala, L. Lyytikäinen, B. Hamal Mishra +6 more
2023Psychological Medicine6 citations Open access
Semantic Scholar
C-type lectin receptor CLEC4A2 promotes tissue adaptation of macrophages and protects against atherosclerosis
Inhye Park, M. Goddard, J. Cole, Natacha Zanin +7 more
2022Nature Communications6 citations Open access
Semantic Scholar
Prevalence and long-term prognostic implications of prolonged QRS duration in left ventricular hypertrophy: a population-based observational cohort study
J. Rankinen, Petri Haataja, L. Lyytikäinen, H. Huhtala +9 more
2022BMJ Open6 citations Open access
Semantic Scholar
Publisher Correction: A meta-analysis of genome-wide association studies identifies multiple longevity genes
J. Deelen, D. Evans, D. Arking, N. Tesi +80 more
2021Nature Communications6 citations Open access
Semantic Scholar
Functional Polymorphisms in Oxytocin and Dopamine Pathway Genes and the Development of Dispositional Compassion Over Time: The Young Finns Study
Henrik Dobewall, A. Saarinen, L. Lyytikäinen, L. Keltikangas-Järvinen +2 more
2021Frontiers in Psychology6 citations Open access
Semantic Scholar
Relation of intraventricular conduction delay to risk of new-onset heart failure and structural heart disease in the general population
J. Rankinen, Petri Haataja, L. Lyytikäinen, H. Huhtala +8 more
2020International Journal of Cardiology: Heart & Vasculature6 citations Open access
Semantic Scholar
Genetic risk score for coronary artery calcification and its predictive ability for coronary artery disease
P. P. Mishra, B. Mishra, L. Lyytikäinen, S. Goebeler +8 more
2024American Journal of Preventive Cardiology5 citations Open access
Semantic Scholar
Polygenic risk for schizophrenia, social dispositions, and pace of epigenetic aging: Results from the Young Finns Study
A. Saarinen, S. Marttila, Pashupati P. Mishra, L. Lyytikäinen +8 more
2023Aging Cell5 citations Open access
Semantic Scholar
High-risk ECG patterns in ST elevation myocardial infarction for mortality prediction.
R. Lahti, J. Rankinen, L. Lyytikäinen, M. Eskola +2 more
2022Journal of Electrocardiology5 citations Open access
Semantic Scholar
Interatrial block and P terminal force in the general population - Longitudinal changes, risk factors and prognosis.
Tiia Istolahti, Antti Eranti, H. Huhtala, J. Tynkkynen +8 more
2022Journal of Electrocardiology5 citations Open access
Semantic Scholar
Variants associated with HHIP expression have sex-differential effects on lung function
K. Fawcett, M. Obeidat, C. Melbourne, N. Shrine +71 more
2020Wellcome Open Research5 citations Open access
Semantic Scholar
Performance of the 12-lead ECG in predicting short- and long-term risk of sudden cardiac death
J. Hernesniemi, Teemu Pukkila, J. Rankinen, Antti Kallonen +5 more
2026npj Digit. Medicine4 citations Open access
Semantic Scholar
Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus
K. Freimann, Anneke Brümmer, R. Warmerdam, T. Rupall +136 more
2025Nature Communications4 citations Open access
Semantic Scholar
Polygenic risk for schizophrenia predicting Big Five personality traits in individuals without non-affective psychosis.
Veikka Lavonius, L. Keltikangas-Järvinen, L. Lyytikäinen, B. Hamal Mishra +6 more
2025Schizophrenia Research4 citations Open access
Semantic Scholar
Regulation of nc886 (vtRNA2-1) RNAs is associated with cardiometabolic risk factors and diseases
S. Rajić, T. Delerue, J. Ronkainen, Ruiyuan Zhang +20 more
2025Clinical Epigenetics4 citations Open access
Semantic Scholar
Early resilience and epigenetic ageing: Results from the prospective Young Finns Study with a 31‐year follow‐up
A. Saarinen, S. Marttila, Pashupati P. Mishra, L. Lyytikäinen +7 more
2024Aging Cell4 citations Open access
Semantic Scholar
The association between GRACE score at admission for myocardial infarction and the incidence of sudden cardiac arrests in long-term follow-up – the MADDEC study
Markus Hautamäki, Minna Järvensivu-Koivunen, L. Lyytikäinen, M. Eskola +5 more
2024Scandinavian Cardiovascular Journal4 citations Open access
Semantic Scholar
Repeated heart rate variability monitoring after myocardial infraction – Cohort profile of the MI-ECG study
Teemu Pukkila, J. Rankinen, L. Lyytikäinen, N. Oksala +3 more
2025International Journal of Cardiology: Heart & Vasculature3 citations Open access
Semantic Scholar
Leptin and leptin receptor gene polymorphisms and depression treatment response
Ida-Maria Tavast, A. Solismaa, L. Lyytikäinen, N. Mononen +4 more
2024Acta Neuropsychiatrica3 citations Open access
Semantic Scholar

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