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J. Fessel · SciRah

Researcher profile · Semantic Scholar

J. Fessel

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J. Fessel — researcher profile on SciRah

h-index: 39
Works: 106
Citations: 4,967

Most-cited papers

Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension.
T. Bertero, W. M. Oldham, K. Cottrill, S. Pisano +27 more
2016Journal of Clinical Investigation379 citations Open access
Semantic Scholar
Sirt3 Impairment and SOD2 Hyperacetylation in Vascular Oxidative Stress and Hypertension
A. Dikalova, Hana A. Itani, R. Nazarewicz, W. McMaster +6 more
2017Circulation Research268 citations Open access
Semantic Scholar
Isoprostanes and related products of lipid peroxidation in neurodegenerative diseases.
K. Montine, J. Quinn, Jing Zhang, J. Fessel +3 more
2004Chemistry and Physics of Lipids252 citations
Semantic Scholar
A Metabolic Basis for Endothelial-to-Mesenchymal Transition
J. Xiong, H. Kawagishi, Ye Yan, Jie Liu +10 more
2018Molecules and Cells247 citations Open access
Semantic Scholar
Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension
E. Brittain, M. Talati, J. Fessel, He Zhu +11 more
2016Circulation222 citations Open access
Semantic Scholar
A potential therapeutic role for Angiotensin Converting Enzyme 2 in human pulmonary arterial hypertension
A. Hemnes, A. Rathinasabapathy, E. Austin, E. Brittain +18 more
2018European Respiratory Journal207 citations Open access
Semantic Scholar
The biochemistry of the isoprostane, neuroprostane, and isofuran Pathways of lipid peroxidation.
L. Roberts, J. Fessel, S. Davies
2004Brain Pathology191 citations
Semantic Scholar
Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension.
A. Hemnes, E. Brittain, A. Trammell, J. Fessel +8 more
2014American Journal of Respiratory and Critical Care Medicine174 citations Open access
Semantic Scholar
Oxidative Mediated Lipid Peroxidation Recapitulates Proarrhythmic Effects on Cardiac Sodium Channels
K. Fukuda, Sean S. Davies, T. Nakajima, Boonhooi Ong +8 more
2005Circulation Research135 citations Open access
Semantic Scholar
A potential role for insulin resistance in experimental pulmonary hypertension
J. West, K. Niswender, Jennifer A. Johnson, M. Pugh +3 more
2012European Respiratory Journal123 citations Open access
Semantic Scholar
Orthostatic hypertension: when pressor reflexes overcompensate
J. Fessel, D. Robertson
2006Nature Clinical Practice Nephrology109 citations
Semantic Scholar
Mechanisms of Lipid Accumulation in the Bone Morphogenetic Protein Receptor Type 2 Mutant Right Ventricle.
M. Talati, E. Brittain, J. Fessel, Niki L. Penner +8 more
2016American Journal of Respiratory and Critical Care Medicine103 citations Open access
Semantic Scholar
Human PAH is characterized by a pattern of lipid-related insulin resistance.
A. Hemnes, J. Luther, Christopher J. Rhodes, Jason P. Burgess +23 more
2019JCI Insight101 citations Open access
Semantic Scholar
Plasma Biomarkers of Oxidant Stress and Development of Organ Failure in Severe Sepsis
L. Ware, J. Fessel, A. May, L. Roberts
2011Shock92 citations Open access
Semantic Scholar
The Estrogen Metabolite 16αOHE Exacerbates BMPR2-Associated PAH Through miR-29-Mediated Modulation of Cellular Metabolism
Xinping Chen, M. Talati, J. Fessel, A. Hemnes +16 more
2015Circulation87 citations Open access
Semantic Scholar
Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension.
A. Bryant, Ryan P. Carrick, Melinda E. McConaha, Brittany R. Jones +22 more
2016American Journal of Physiology - Lung cellular and Molecular Physiology85 citations Open access
Semantic Scholar
Dysfunctional BMPR2 signaling drives an abnormal endothelial requirement for glutamine in pulmonary arterial hypertension
Robert A. Egnatchik, E. Brittain, A. Shah, W. Fares +15 more
2017Pulmonary Circulation80 citations Open access
Semantic Scholar
Estrogen Inhibition Reverses Pulmonary Arterial Hypertension and Associated Metabolic Defects
Xinping Chen, E. Austin, M. Talati, J. Fessel +5 more
2017European Respiratory Journal74 citations Open access
Semantic Scholar
Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling
Kelsey S. Chow, J. Fessel, KaoriIhida-Stansbury, E. Schmidt +9 more
2013Pulmonary Circulation71 citations Open access
Semantic Scholar
Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension.
J. West, Eric D. Austin, Christa F. Gaskill, S. Marriott +21 more
2014American Journal of Physiology - Cell Physiology67 citations Open access
Semantic Scholar
The Biochemistry of the Isoprostane, Neuroprostane, and Isofuran Pathways of Lipid Peroxidation
L. Roberts, J. Fessel, Sean S. Davies
2005Chemistry and Physics of Lipids67 citations Open access
Semantic Scholar
Kidney dysfunction in patients with pulmonary arterial hypertension
N. Nickel, J. O'leary, E. Brittain, J. Fessel +3 more
2017Pulmonary Circulation66 citations Open access
Semantic Scholar
The genetics of pulmonary arterial hypertension in the post-BMPR2 era
J. Fessel, J. Loyd, E. Austin
2011Pulmonary Circulation64 citations Open access
Semantic Scholar
LKB1 deficiency enhances sensitivity to energetic stress induced by erlotinib treatment in non-small cell lung cancer (NSCLC) cells
Y. M. Whang, S. I. Park, Irina A. Trenary, Robert A. Egnatchik +4 more
2015Oncogene61 citations Open access
Semantic Scholar
Oxidative injury is a common consequence of BMPR2 mutations
Kirk L. Lane, M. Talati, E. Austin, A. Hemnes +8 more
2011Pulmonary Circulation61 citations Open access
Semantic Scholar
Localization of isoketal adducts in vivo using a single-chain antibody.
Sean S. Davies, Meghavi Talati, Xia-Hong Wang, Raymond L. Mernaugh +5 more
2004Free Radical Biology & Medicine60 citations
Semantic Scholar
Interaction between Bone Morphogenetic Protein Receptor Type 2 and Estrogenic Compounds in Pulmonary Arterial Hypertension
J. Fessel, Xinping Chen, A. Frump, S. Gladson +7 more
2013Pulmonary Circulation55 citations Open access
Semantic Scholar
Isofurans: Novel Products of Lipid Peroxidation that Define the Occurrence of Oxidant Injury in Settings of Elevated Oxygen Tension
J. Fessel, L. Roberts
2005Antioxidants and Redox Signaling54 citations
Semantic Scholar
Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer’s disease and a novel protective role for ascorbate
S. Dixit, J. Fessel, F. Harrison
2017Free Radical Biology & Medicine53 citations Open access
Semantic Scholar
Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults
Q. Wells, Olivia J. Veatch, J. Fessel, Aron Y. Joon +20 more
2017Pharmacogenetics & Genomics53 citations Open access
Semantic Scholar
Ascorbic acid attenuates endothelial permeability triggered by cell-free hemoglobin
Jamie L. Kuck, J. Bastarache, C. Shaver, J. Fessel +3 more
2017Biochemical and Biophysical Research Communications - BBRC52 citations Open access
Semantic Scholar
Dysautonomia: Perioperative Implications
Hossam I. Mustafa, J. Fessel, John A. Barwise, J. R. Shannon +4 more
2012Anesthesiology51 citations Open access
Semantic Scholar
Seizure‐induced formation of isofurans: novel products of lipid peroxidation whose formation is positively modulated by oxygen tension
Manisha N. Patel, Li-Ping Liang, H. Hou, Benjamin B. Williams +4 more
2007Journal of Neurochemistry48 citations
Semantic Scholar
Multi-organ Abnormalities and mTORC1 Activation in Zebrafish Model of Multiple Acyl-CoA Dehydrogenase Deficiency
Seok-Hyung Kim, Sarah A. Scott, M. Bennett, Robert P. Carson +3 more
2013PLoS Genetics47 citations Open access
Semantic Scholar
Oxidative stress increases M1dG, a major peroxidation-derived DNA adduct, in mitochondrial DNA
Orrette R Wauchope, M. M. Mitchener, William N. Beavers, J. Galligan +9 more
2018Nucleic Acids Research41 citations Open access
Semantic Scholar
Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension.
J. Fessel, C. Flynn, Linda J. Robinson, Niki L. Penner +5 more
2013American Journal of Respiratory Cell and Molecular Biology40 citations Open access
Semantic Scholar
Pyridine Dinucleotides from Molecules to Man
J. Fessel, W. Oldham
2018Antioxidants and Redox Signaling32 citations Open access
Semantic Scholar
A process-based review of mouse models of pulmonary hypertension
M. Das, J. Fessel, Hai-Yang Tang, J. West
2012Pulmonary Circulation32 citations Open access
Semantic Scholar
Mitochondrial DNA depletion by ethidium bromide decreases neuronal mitochondrial creatine kinase: Implications for striatal energy metabolism
E. B. Warren, Aidan Aicher, J. Fessel, C. Konradi
2017PLoS ONE31 citations Open access
Semantic Scholar
Expression of Mutant Bone Morphogenetic Protein Receptor II Worsens Pulmonary Hypertension Secondary to Pulmonary Fibrosis
A. Bryant, Linda J. Robinson, C. Moore, T. Blackwell +14 more
2015Pulmonary Circulation30 citations Open access
Semantic Scholar
Neutrophil trafficking to the site of infection requires Cpt1a-dependent fatty acid β-oxidation
Ly Pham, P. Komalavilas, Alex M Eddie, T. Thayer +17 more
2022Communications Biology26 citations Open access
Semantic Scholar
Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study
Christi T. Salisbury-Ruf, Clinton C. Bertram, A. Vergeade, Daniel S. Lark +13 more
2018eLife25 citations Open access
Semantic Scholar
Rescuing the BMPR2 signaling axis in pulmonary arterial hypertension
J. West, E. Austin, J. Fessel, J. Loyd +1 more
2014Drug Discovery Today25 citations Open access
Semantic Scholar
Enhanced expression of catalase in mitochondria modulates NF-κB dependent lung inflammation through alteration of metabolic activity in macrophages
W. Han, J. Fessel, T. Sherrill, E. Kocurek +2 more
2020Journal of Immunology24 citations Open access
Semantic Scholar
Scavengers of reactive γ-ketoaldehydes extend Caenorhabditis elegans lifespan and healthspan through protein-level interactions with SIR-2.1 and ETS-7
T. T. Nguyen, S. Caito, W. Zackert, J. West +4 more
2016Aging24 citations Open access
Semantic Scholar
Redox Biology in Pulmonary Arterial Hypertension (2013 Grover Conference Series)
J. Fessel, J. West
2015Pulmonary Circulation24 citations Open access
Semantic Scholar
Shared Gene Expression Patterns in Mesenchymal Progenitors Derived from Lung and Epidermis in Pulmonary Arterial Hypertension: Identifying Key Pathways in Pulmonary Vascular Disease
Christa F. Gaskill, S. Marriott, S. Pratap, S. Menon +11 more
2016Pulmonary Circulation23 citations Open access
Semantic Scholar
Transbronchial Cryobiopsy Can Diagnose Constrictive Bronchiolitis in Veterans of Recent Conflicts in the Middle East.
R. Lentz, J. Fessel, Joyce E. Johnson, F. Maldonado +2 more
2016American Journal of Respiratory and Critical Care Medicine22 citations Open access
Semantic Scholar
BMPR2 dysfunction impairs insulin signaling and glucose homeostasis in cardiomyocytes.
A. Hemnes, J. Fessel, Xinping Chen, Shijun Zhu +6 more
2019American Journal of Physiology - Lung cellular and Molecular Physiology21 citations Open access
Semantic Scholar
Pulmonary vascular effect of insulin in a rodent model of pulmonary arterial hypertension
A. Trammell, M. Talati, T. Blackwell, N. Fortune +5 more
2017Pulmonary Circulation21 citations Open access
Semantic Scholar

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A. Hemnes×18
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J. West×13
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E. Brittain×10
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E. Austin×9
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M. Talati — researcher profile on SciRah

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J. Loyd — researcher profile on SciRah

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L. Roberts — researcher profile on SciRah