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D. Smee · SciRah

Researcher profile · Semantic Scholar

D. Smee

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D. Smee — researcher profile on SciRah

h-index: 63
Works: 299
Citations: 13K

Most-cited papers

Favipiravir (T-705), a novel viral RNA polymerase inhibitor
Y. Furuta, B. Gowen, Kazumi Takahashi, K. Shiraki +2 more
2013Antiviral Research1,011 citations Open access
Semantic Scholar
T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections
Y. Furuta, Kazumi Takahashi, K. Shiraki, K. Sakamoto +5 more
2009Antiviral Research470 citations Open access
Semantic Scholar
Triple Combination of Amantadine, Ribavirin, and Oseltamivir Is Highly Active and Synergistic against Drug Resistant Influenza Virus Strains In Vitro
J. Nguyen, Justin D. Hoopes, M. H. Le, D. Smee +6 more
2010PLoS ONE177 citations Open access
Semantic Scholar
PSI-7851, a Pronucleotide of β-d-2′-Deoxy-2′-Fluoro-2′-C-Methyluridine Monophosphate, Is a Potent and Pan-Genotype Inhibitor of Hepatitis C Virus Replication
A. Lam, E. Murakami, C. Espiritu, H. M. Micolochick Steuer +16 more
2010Antimicrobial Agents and Chemotherapy146 citations Open access
Semantic Scholar
The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses
E. Pécheur, V. Borisevich, Peter J. Halfmann, J. Morrey +6 more
2016Journal of Virology144 citations Open access
Semantic Scholar
Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity
Michael D. Swanson, Daniel M. Boudreaux, Loïc Salmon, J. Chugh +22 more
2015Cell111 citations Open access
Semantic Scholar
Triple Combination of Oseltamivir, Amantadine, and Ribavirin Displays Synergistic Activity against Multiple Influenza Virus Strains In Vitro
J. Nguyen, Justin D. Hoopes, D. Smee, M. Prichard +6 more
2009Antimicrobial Agents and Chemotherapy111 citations Open access
Semantic Scholar
Synthesis and Biological Evaluation of Epidithio-, Epitetrathio- and bis-(Methylthio)diketopiperazines. Synthetic Methodology, Enantioselective Total Synthesis of Epicoccin G, 8,8′-epi-ent-Rostratin B, Gliotoxin, Gliotoxin G, Emethallicin E and Haematocin, and Discovery of New Antiviral and Antimala
K. Nicolaou, Min Lu, Sotirios Totokotsopoulos, P. Heretsch +9 more
2012Journal of the American Chemical Society105 citations Open access
Semantic Scholar
T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture
M. Mendenhall, A. Russell, T. Juelich, Emily L Messina +7 more
2010Antimicrobial Agents and Chemotherapy105 citations Open access
Semantic Scholar
Effective Oral Favipiravir (T-705) Therapy Initiated after the Onset of Clinical Disease in a Model of Arenavirus Hemorrhagic Fever
M. Mendenhall, A. Russell, D. Smee, J. Hall +3 more
2011PLoS Neglected Tropical Diseases100 citations Open access
Semantic Scholar
Efficacy of Combined Therapy with Amantadine, Oseltamivir, and Ribavirin In Vivo against Susceptible and Amantadine-Resistant Influenza A Viruses
J. Nguyen, D. Smee, D. Barnard, J. Julander +3 more
2012PLoS ONE97 citations Open access
Semantic Scholar
Effects of Double Combinations of Amantadine, Oseltamivir, and Ribavirin on Influenza A (H5N1) Virus Infections in Cell Culture and in Mice
D. Smee, Brett L. Hurst, M. Wong, K. Bailey +1 more
2009Antimicrobial Agents and Chemotherapy90 citations Open access
Semantic Scholar
Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutinin
Y. Kumaki, M. Wandersee, Aaron Smith, Yan-Chen Zhou +8 more
2010Antiviral Research89 citations Open access
Semantic Scholar
Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones
D. Havrylyuk, B. Zimenkovsky, O. Vasylenko, C. Day +3 more
2013European journal of medicinal chemistry87 citations Open access
Semantic Scholar
BCX4430, a Novel Nucleoside Analog, Effectively Treats Yellow Fever in a Hamster Model
J. Julander, S. Bantia, Brian R. Taubenheim, Dena M. Minning +5 more
2014Antimicrobial Agents and Chemotherapy79 citations Open access
Semantic Scholar
Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus 87 strains to various antiviral compounds
D. Smee, W. J. Evans, K. Nicolaou, E. Tarbet +1 more
2016Antiviral Research75 citations Open access
Semantic Scholar
Evaluation of Cell Viability Dyes in Antiviral Assays with RNA Viruses that Exhibit Different Cytopathogenic Properties
D. Smee, Brett L. Hurst, W. J. Evans, Nathan R. Clyde +4 more
2017Journal of Virological Methods73 citations Open access
Semantic Scholar
Effect of T-705 treatment on western equine encephalitis in a mouse model
J. Julander, D. Smee, J. Morrey, Y. Furuta
2009Antiviral Research70 citations Open access
Semantic Scholar
Efficacy of favipiravir (T-705) and T-1106 pyrazine derivatives in phlebovirus disease models
B. Gowen, M. Wong, Kie-Hoon Jung, D. Smee +2 more
2009Antiviral Research66 citations Open access
Semantic Scholar
A molecularly engineered antiviral banana lectin inhibits fusion and is efficacious against influenza virus infection in vivo
Evelyn M. Covés-Datson, Steven R. King, M. Legendre, Auroni Gupta +10 more
2020Proceedings of the National Academy of Sciences of the United States of America64 citations Open access
Semantic Scholar
Combinations of favipiravir and peramivir for the treatment of pandemic influenza A/California/04/2009 (H1N1) virus infections in mice
E. Tarbet, M. Maekawa, Y. Furuta, Y. Babu +2 more
2012Antiviral Research64 citations Open access
Semantic Scholar
Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever viruses
Jonna L. B. Westover, E. Sefing, K. Bailey, A. V. Van Wettere +8 more
2015Antiviral Research63 citations Open access
Semantic Scholar
A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response
Merika T. Koday, Jorgen W. Nelson, Aaron Chevalier, Michael Koday +11 more
2016PLoS Pathogens58 citations Open access
Semantic Scholar
Inhibition of Influenza a Virus Replication by Antagonism of a PI3K-AKT-mTOR Pathway Member Identified by Gene-Trap Insertional Mutagenesis
J. Murray, Natalie J. Mcdonald, Jinsong Sheng, M. Shaw +4 more
2012Antiviral Chemistry & Chemotherapy57 citations Open access
Semantic Scholar
An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses
Yanmei Hu, Rami Musharrafieh, Chun-Long Ma, Jian-Tao Zhang +3 more
2017Antiviral Research55 citations Open access
Semantic Scholar
Combinations of oseltamivir and peramivir for the treatment of influenza A (H1N1) virus infections in cell culture and in mice
D. Smee, Brett L. Hurst, M. Wong, E. Tarbet +3 more
2010Antiviral Research53 citations Open access
Semantic Scholar
A Heterocyclic Molecule with Significant Activity Against Dengue Virus
V. Nair, Guo-Chen Chi, Qing-Ning Shu, J. Julander +1 more
2009Bioorganic & Medicinal Chemistry Letters53 citations Open access
Semantic Scholar
Synergistic combinations of favipiravir and oseltamivir against wild-type pandemic and oseltamivir-resistant influenza A virus infections in mice
D. Smee, E. Tarbet, Y. Furuta, J. Morrey +1 more
2013Future Virology50 citations Open access
Semantic Scholar
Antivirally Active Ribavirin Analogues – 4,5-disubstituted 1,2,3-triazole Nucleosides: Biological Evaluation against Certain Respiratory Viruses and Computational Modelling
A. Krajczyk, K. Kulińska, T. Kulinski, Brett L. Hurst +5 more
2014Antiviral Chemistry & Chemotherapy47 citations Open access
Semantic Scholar
Efficacy of 2′-C-Methylcytidine Against Yellow Fever Virus in Cell Culture and in a Hamster Model
J. Julander, A. Jha, Jung-ae Choi, Kie-Hoon Jung +3 more
2010Antiviral Research45 citations Open access
Semantic Scholar
Alterations in favipiravir (T-705) pharmacokinetics and biodistribution in a hamster model of viral hemorrhagic fever
B. Gowen, E. Sefing, Jonna L. B. Westover, D. Smee +3 more
2015Antiviral Research40 citations Open access
Semantic Scholar
Development of a New Tacaribe Arenavirus Infection Model and Its Use to Explore Antiviral Activity of a Novel Aristeromycin Analog
B. Gowen, M. Wong, Deanna P Larson, Wei Ye +6 more
2010PLoS ONE39 citations Open access
Semantic Scholar
In vitro and in vivo efficacy of fluorodeoxycytidine analogs against highly pathogenic avian influenza H5N1, seasonal, and pandemic H1N1 virus infections
Y. Kumaki, C. Day, D. Smee, J. Morrey +1 more
2011Antiviral Research38 citations Open access
Semantic Scholar
Evaluation of antiviral therapies in respiratory and neurological disease models of Enterovirus D68 infection in mice.
Brett L. Hurst, W. J. Evans, D. Smee, A. V. Van Wettere +1 more
2018Virology37 citations Open access
Semantic Scholar
2′‐Fluoro‐2′‐deoxycytidine is a broad‐spectrum inhibitor of bunyaviruses in vitro and in phleboviral disease mouse models
D. Smee, Kie-Hoon Jung, Jonna L. B. Westover, B. Gowen
2018Antiviral Research37 citations
Semantic Scholar
Maporal virus as a surrogate for pathogenic New World hantaviruses and its inhibition by favipiravir
Kristin K Buys, Kie-Hoon Jung, D. Smee, Y. Furuta +1 more
2011Antiviral Chemistry & Chemotherapy37 citations Open access
Semantic Scholar
The Iminosugar UV-4 is a Broad Inhibitor of Influenza A and B Viruses ex Vivo and in Mice
Kelly L. Warfield, D. Barnard, Sven Enterlein, D. Smee +5 more
2016Viruses36 citations Open access
Semantic Scholar
In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus
E. Tarbet, A. Vollmer, Brett L. Hurst, D. Barnard +2 more
2014Archives of Virology36 citations Open access
Semantic Scholar
Development of a Respiratory Disease Model for Enterovirus D68 in 4-Week-Old Mice for Evaluation of Antiviral Therapies
Joseph Evans, Brett L. Hurst, C. Peterson, A. V. Van Wettere +3 more
2018Antiviral Research35 citations Open access
Semantic Scholar
D282, a Non-Nucleoside Inhibitor of Influenza Virus Infection that Interferes with de novo Pyrimidine Biosynthesis
D. Smee, Brett L. Hurst, C. Day
2012Antiviral Chemistry & Chemotherapy35 citations Open access
Semantic Scholar
Activities of JNJ63623872 and oseltamivir against influenza A H1N1pdm and H3N2 virus infections in mice.
D. Smee, D. Barnard, Steven J. M. Jones
2016Antiviral Research32 citations
Semantic Scholar
A human recombinant analogue to plasma-derived vaccinia immunoglobulin prophylactically and therapeutically protects against lethal orthopoxvirus challenge
S. Parker, J. D’Angelo, R. Buller, D. Smee +5 more
2021Antiviral Research28 citations Open access
Semantic Scholar
Exacerbation of Influenza Virus Infections in Mice by Intranasal Treatments and Implications for Evaluation of Antiviral Drugs
D. Smee, M. von Itzstein, B. Bhatt, E. Tarbet
2012Antimicrobial Agents and Chemotherapy28 citations Open access
Semantic Scholar
Discovery of Novel Benzoquinazolinones and Thiazoloimidazoles, Inhibitors of Influenza H5N1 and H1N1 Viruses, from a Cell-Based High-Throughput Screen
J. Maddry, Xi Chen, Colleen B. Jonsson, S. Ananthan +10 more
2010Journal of biomolecular screening26 citations Open access
Semantic Scholar
Isolation and identification of compounds from Kalanchoe pinnata having human alphaherpesvirus and vaccinia virus antiviral activity
Matthew A. Cryer, Kyle Lane, M. Greer, R. Cates +10 more
2017Pharmaceutical Biology24 citations Open access
Semantic Scholar
Innate immune protection against infectious diseases by pulmonary administration of a phospholipid conjugated TLR7 ligand
Christina N. Wu, B. Crain, Shiyin Yao, M. Sabet +10 more
2013Journal of Innate Immunity22 citations Open access
Semantic Scholar
Orthopoxvirus inhibitors that are active in animal models: an update from 2008 to 2012
D. Smee
2013Future Virology21 citations Open access
Semantic Scholar
Treatment of Oseltamivir-Resistant Influenza A (H1N1) Virus Infections in Mice With Antiviral Agents
D. Smee, J. Julander, E. Tarbet, M. Gross +1 more
2012Antiviral Research21 citations Open access
Semantic Scholar
A zanamivir dimer with prophylactic and enhanced therapeutic activity against influenza viruses.
E. Tarbet, Stephanie M. Hamilton, A. Vollmer, Angela Luttick +6 more
2014Journal of Antimicrobial Chemotherapy19 citations Open access
Semantic Scholar
The use of plethysmography in determining the severity of lung pathology in a mouse model of minimally lethal influenza virus infection.
J. Julander, Kyle K. Kesler, A. V. Van Wettere, J. Morrey +1 more
2014Antiviral Research17 citations
Semantic Scholar

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J. Morrey×14
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J. Morrey — researcher profile on SciRah
Y. Furuta×12
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Y. Furuta — researcher profile on SciRah
E. Tarbet×11
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E. Tarbet — researcher profile on SciRah
B. Gowen×10
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J. Julander — researcher profile on SciRah

Brett L. Hurst×10

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Brett L. Hurst — researcher profile on SciRah

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C. Day — researcher profile on SciRah

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D. Barnard — researcher profile on SciRah

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Kie-Hoon Jung — researcher profile on SciRah

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J. Nguyen — researcher profile on SciRah

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