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J. Yeh · SciRah

Researcher profile · Semantic Scholar

J. Yeh

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J. Yeh — researcher profile on SciRah

h-index: 50
Works: 180
Citations: 10K

Most-cited papers

Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial
K. Aung, S. Fischer, R. Denroche, G. Jang +30 more
2017Clinical Cancer Research530 citations Open access
Semantic Scholar
Antitumor Responses in the Absence of Toxicity in Solid Tumors by Targeting B7-H3 via Chimeric Antigen Receptor T Cells
Hongwei Du, K. Hirabayashi, Sarah Ahn, N. Kren +18 more
2019Cancer Cell421 citations Open access
Semantic Scholar
Analysis of 13 cell types reveals evidence for the expression of numerous novel primate- and tissue-specific microRNAs
Eric Londin, Phillipe Loher, Aristeidis G. Telonis, K. Quann +34 more
2015Proceedings of the National Academy of Sciences of the United States of America414 citations Open access
Semantic Scholar
Real-time genomic characterization of advanced pancreatic cancer to enable precision medicine
Andrew J. Aguirre, J. Nowak, Nicholas D. Camarda, R. Moffitt +57 more
2018Cancer Discovery306 citations Open access
Semantic Scholar
Purity Independent Subtyping of Tumors (PurIST), a clinically robust, single sample classifier for tumor subtyping in pancreatic cancer
N. Rashid, X. Peng, C. Jin, R. Moffitt +15 more
2019Clinical Cancer Research192 citations Open access
Semantic Scholar
Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancer
Marybeth Anderson, Raoud Marayati, R. Moffitt, J. Yeh
2016OncoTarget173 citations Open access
Semantic Scholar
Altered exocrine function can drive adipose wasting in early pancreatic cancer
Laura V. Danai, A. Babic, M. Rosenthal, Emily A. Dennstedt +25 more
2018Nature132 citations Open access
Semantic Scholar
The PDAC Extracellular Matrix: A Review of the ECM Protein Composition, Tumor Cell Interaction, and Therapeutic Strategies
Vincent M. Perez, J. Kearney, J. Yeh
2021Frontiers in Oncology125 citations Open access
Semantic Scholar
Pancreatic ductal adenocarcinoma progression is restrained by stromal matrix.
Hong-Lin Jiang, R. Torphy, K. Steiger, H. Hongo +19 more
2020Journal of Clinical Investigation103 citations Open access
Semantic Scholar
B cell–derived IL35 drives STAT3-dependent CD8+ T-cell exclusion in pancreatic cancer
B. Mirlekar, Daniel Michaud, Samuel J. Lee, N. Kren +13 more
2020Cancer immunology research99 citations Open access
Semantic Scholar
Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation
Y. Kano, T. Gebregiworgis, C. Marshall, N. Radulovich +15 more
2019Nature Communications95 citations Open access
Semantic Scholar
N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration
I. Rigoutsos, Sang Kill Lee, S. Nam, S. Anfossi +44 more
2017Genome Biology91 citations Open access
Semantic Scholar
Stromal Content Is Correlated With Tissue Site, Contrast Retention, and Survival in Pancreatic Adenocarcinoma
R. Torphy, Zhen Wang, A. True-Yasaki, Keith E. Volmar +7 more
2018JCO Precision Oncology88 citations Open access
Semantic Scholar
MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma
Sean T. Bailey, Aleisha M. Smith, Jordan Kardos, S. Wobker +19 more
2017Nature Communications81 citations Open access
Semantic Scholar
GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity
L. Ruffolo, K. Jackson, Peyton C. Kuhlers, B. Dale +19 more
2021Gut67 citations Open access
Semantic Scholar
Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity
B. Mirlekar, Yan Wang, Sirui Li, Mi Zhou +11 more
2022Cell Reports Medicine65 citations Open access
Semantic Scholar
Use of iontophoresis for the treatment of cancer
J. Byrne, J. Yeh, J. DeSimone
2018Journal of Controlled Release62 citations
Semantic Scholar
PCSK9 drives sterol-dependent metastatic organ choice in pancreatic cancer
Gilles Rademaker, Grace A Hernandez, Yurim Seo, Sumena Dahal +20 more
2025Nature59 citations Open access
Semantic Scholar
Isoforms of MUC16 Activate Oncogenic Signaling Through EGF Receptors to Enhance the Progression of Pancreatic Cancer.
D. Thomas, S. Sagar, Xiang Liu, Hye-Rim Lee +19 more
2020Molecular Therapy57 citations Open access
Semantic Scholar
The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors
T. Gebregiworgis, Y. Kano, J. St-Germain, N. Radulovich +18 more
2021Nature Communications51 citations Open access
Semantic Scholar
De novo compartment deconvolution and weight estimation of tumor samples using DECODER
X. Peng, R. Moffitt, R. Torphy, Keith E. Volmar +1 more
2019Nature Communications48 citations Open access
Semantic Scholar
Impact of neoadjuvant therapy on postoperative outcomes after pancreaticoduodenectomy
K. Cools, H. Sanoff, Hong-Jin Kim, J. Yeh +1 more
2018Journal of Surgical Oncology47 citations Open access
Semantic Scholar
Single-cell transcriptome analysis defines heterogeneity of the murine pancreatic ductal tree
Audrey M. Hendley, A. Rao, Laura Leonhardt, Sudipta Ashe +16 more
2021eLife39 citations Open access
Semantic Scholar
Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability
Jeran K. Stratford, Feng Yan, R. Hill, M. B. Major +3 more
2017PLoS ONE36 citations Open access
Semantic Scholar
Discrete microfluidics for the isolation of circulating tumor cell subpopulations targeting fibroblast activation protein alpha and epithelial cell adhesion molecule
Malgorzata A. Witek, R. Aufforth, Hong Wang, Joyce W. Kamande +17 more
2017npj Precision Oncology36 citations Open access
Semantic Scholar
Metformin Treatment Does Not Inhibit Growth of Pancreatic Cancer Patient-Derived Xenografts
Matthew B Lipner, Raoud Marayati, Yangmei Deng, Xian-Xi Wang +3 more
2016PLoS ONE36 citations Open access
Semantic Scholar
Irreversible JNK1-JUN inhibition by JNK-IN-8 sensitizes pancreatic cancer to 5-FU/FOLFOX chemotherapy.
Matthew B Lipner, X. Peng, C. Jin, Yi Xu +11 more
2020JCI Insight30 citations Open access
Semantic Scholar
Gene Targeting in Disease Networks
Deborah A. Weighill, M. Ben Guebila, Kimberly Glass, John Platig +2 more
2021Frontiers in Genetics26 citations Open access
Semantic Scholar
Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
D. R. Cook, M. Kang, Timothy D. Martin, J. Galanko +21 more
2021Cancer Research26 citations Open access
Semantic Scholar
Open-source curation of a pancreatic ductal adenocarcinoma gene expression analysis platform (pdacR) supports a two-subtype model
L. Torre-Healy, R. Kawalerski, Ki Oh, Lucie Chrastecka +5 more
2023Communications Biology23 citations Open access
Semantic Scholar
Sub-Cluster Identification through Semi-Supervised Optimization of Rare-Cell Silhouettes (SCISSORS) in single-cell RNA-sequencing
J. R. Leary, Yi Xu, A. Morrison, C. Jin +6 more
2023Bioinform.23 citations Open access
Semantic Scholar
Iontophoretic device delivery for the localized treatment of pancreatic ductal adenocarcinoma
J. Byrne, Mohammad Raheel Jajja, Allison N. Schorzman, Amanda W. Keeler +4 more
2016Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
Selective single cell isolation for genomics using microraft arrays
Joshua D. Welch, Lindsay A. Williams, Matthew DiSalvo, A. Brandt +6 more
2016Nucleic Acids Research22 citations Open access
Semantic Scholar
Enhanced Efficacy of Combination of Gemcitabine and Phosphatidylserine-Targeted Nanovesicles against Pancreatic Cancer.
Kombo F. N'guessan, H. Davis, Zhengtao Chu, Subrahmanya D. Vallabhapurapu +7 more
2020Molecular Therapy21 citations Open access
Semantic Scholar
Truncated O-Glycan-Bearing MUC16 Enhances Pancreatic Cancer Cells Aggressiveness via α4β1 Integrin Complexes and FAK Signaling
Christabelle Rajesh, S. Sagar, A. Rathinavel, Divya T. Chemparathy +4 more
2022International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
The vitamin D receptor gene as a determinant of survival in pancreatic cancer patients: Genomic analysis and experimental validation
F. Innocenti, K. Owzar, Chen Jiang, A. Etheridge +20 more
2018PLoS ONE16 citations Open access
Semantic Scholar
Myofibroblastic cancer-associated fibroblast subtype heterogeneity in pancreatic cancer
Joseph F Kearney, Hannah E. Trembath, Priscilla S Chan, Ashley B Morrison +7 more
2024Journal of Surgical Oncology15 citations Open access
Semantic Scholar
Tumor Mitotic Rate and Association with Recurrence in Sentinel Lymph Node Negative Stage II Melanoma Patients
S. Laks, M. Meyers, A. Deal, Jill S. Frank +4 more
2017The American surgeon14 citations Open access
Semantic Scholar
Pan-lysyl oxidase inhibition disrupts fibroinflammatory tumor stroma, rendering cholangiocarcinoma susceptible to chemotherapy
P. Burchard, L. Ruffolo, N. Ullman, B. Dale +17 more
2024Hepatology Communications12 citations Open access
Semantic Scholar
PurIST Pancreatic Cancer Classifier: Analytic Validation of a 16-RNA Expression Signature Distinguishing Basal and Classical Subtypes.
Yan Li, Jason D. Merker, Rachana Kshatriya, D. Trembath +5 more
2024Journal of Molecular Diagnostics10 citations
Semantic Scholar
High-Dimensional Precision Medicine From Patient-Derived Xenografts
N. Rashid, Daniel J. Luckett, Jing-Xian Chen, Michael T. Lawson +7 more
2019Journal of the American Statistical Association10 citations Open access
Semantic Scholar
Impact of formulation on the iontophoretic delivery of the FOLFIRINOX regimen for the treatment of pancreatic cancer
J. Byrne, M. R. Jajja, A. O'Neill, Allison N. Schorzman +5 more
2018Cancer Chemotherapy and Pharmacology10 citations Open access
Semantic Scholar
Pathology and Molecular Characteristics of Pancreatic Cancer
J. Kearney, V. Adsay, J. Yeh
2021Surgical Oncology Clinics of North America9 citations Open access
Semantic Scholar
Advances in RAS Therapeutics for Pancreatic Cancer.
C. Der, J. Yeh
2026New England Journal of Medicine7 citations
Semantic Scholar
Tumor-intrinsic and cancer-associated fibroblast subtypes independently predict outcomes in pancreatic cancer
Jaewon J. Lee, Joseph F Kearney, Hannah E. Trembath, Arthi Hariharan +10 more
2024Annals of Surgery7 citations Open access
Semantic Scholar
Integrated single-dose kinome profiling data is predictive of cancer cell line sensitivity to kinase inhibitors
Chinmaya U. Joisa, Kevin A. Chen, Matthew E. Berginski, B. Golitz +4 more
2022bioRxiv7 citations Open access
Semantic Scholar
Vitamin D receptor agonist paricalcitol plus gemcitabine and nab-paclitaxel in patients with metastatic pancreatic cancer.
K. Perez, J. Cleary, T. Karasic, Srivatsan Raghavan +14 more
20207 citations
Semantic Scholar
Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles
B. Bhinder, V. Friedl, Sunantha Sethuraman, D. Risso +93 more
2025Scientific Reports6 citations Open access
Semantic Scholar
Tumor-intrinsic kinome landscape of pancreatic cancer reveals new therapeutic approaches
Yi Xu, X. Peng, Michael P. East, Ian C. McCabe +17 more
2024Cancer Discovery6 citations Open access
Semantic Scholar
CAFomics: convergence to translation for precision stroma approaches.
Ian C. McCabe, X. Peng, Joseph F Kearney, J. Yeh
2024Carcinogenesis6 citations Open access
Semantic Scholar

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