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F. Karoum · SciRah

Researcher profile · Semantic Scholar

F. Karoum

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F. Karoum — researcher profile on SciRah

h-index: 36
Works: 131
Citations: 4,572

Most-cited papers

Restoration of dopaminergic function by grafting of fetal rat substantia nigra to the caudate nucleus: Long‐term behavioral, biochemical, and histochemical studies
W. Freed, Mark J. Perlow, F. Karoum, A. Seiger +3 more
1980Annals of Neurology342 citations
Semantic Scholar
Increased stress response and β–phenylethylamine in MAOB–deficient mice
J. Grimsby, M. Toth, Kevin Chen, T. Kumazawa +5 more
1997Nature Genetics244 citations
Semantic Scholar
Norepinephrine and its metabolites in cerebrospinal fluid, plasma, and urine. Relationship to hypothalamic-pituitary-adrenal axis function in depression.
A. Roy, D. Pickar, J. de Jong, F. Karoum +1 more
1988Archives of General Psychiatry230 citations
Semantic Scholar
Ibotenic acid lesion of the ventral hippocampus differentially affects dopamine and its metabolites in the nucleus accumbens and prefrontal cortex in the rat.
B. Lipska, G. Jaskiw, S. Chrapusta, F. Karoum +1 more
1992Brain Research217 citations
Semantic Scholar
Modulation of nicotinic receptors by opiate receptor agonists in cultured adrenal chromaffin cells
K. Kumakura, F. Karoum, A. Guidotti, E. Costa
1980Nature215 citations
Semantic Scholar
Specific genetic deficiencies of the A and B isoenzymes of monoamine oxidase are characterized by distinct neurochemical and clinical phenotypes.
J. Lenders, G. Eisenhofer, N. Abeling, W. Berger +7 more
1996Journal of Clinical Investigation151 citations Open access
Semantic Scholar
Metabolism of (‐) deprenyl to amphetamine and methamphetamine may be responsible for deprenyl's therapeutic benefit
F. Karoum, Lin-Whei Chuang, T. Eisler, D. Calne +4 more
1982Neurology137 citations
Semantic Scholar
Effect of ibotenic acid lesions of the medial prefrontal cortex on amphetamine-induced locomotion and regional brain catecholamine concentrations in the rat.
G. Jaskiw, F. Karoum, W. Freed, I. Phillips +2 more
1990Brain Research131 citations
Semantic Scholar
Marked reduction in indexes of dopamine metabolism among patients with depression who attempt suicide.
A. Roy, F. Karoum, S. Pollack
1992Archives of General Psychiatry117 citations
Semantic Scholar
Increased stress response and beta-phenylethylamine in MAOB-deficient mice.
J. Grimsby, M. Toth, K. Chen, T. Kumazawa +5 more
1997Nature Genetics100 citations
Semantic Scholar
Effects of hypoxia lasting up to one month on the catecholamine content in rat carotid body.
Ingeborg Hanbauer, F. Karoum, S. Hellström, S. Lahiri
1981Neuroscience94 citations
Semantic Scholar
Catecholamine content of intracerebral adrenal medulla grafts.
W. Freed, F. Karoum, H. E. Spoor, J. Morihisa +2 more
1983Brain Research92 citations
Semantic Scholar
GC/MS Analysis of Anandamide and Quantification of N‐Arachidonoylphosphatidylethanolamides in Various Brain Regions, Spinal Cord, Testis, and Spleen of the Rat
Hsiu-Ying T. Yang, F. Karoum, C. Felder, H. Badger +2 more
1999Journal of Neurochemistry61 citations
Semantic Scholar
Persistently decreased brain dopamine levels and cocaine.
R. Wyatt, F. Karoum, R. Suddath, R. Fawcett
1988Journal of the American Medical Association (JAMA)52 citations
Semantic Scholar
Dopamine release and metabolism in the rat frontal cortex, nucleus accumbens, and striatum: a comparison of acute clozapine and haloperidol
F. Karoum, M. F. Egan
1992British Journal of Pharmacology51 citations Open access
Semantic Scholar
Marked Amine and Amine Metabolite Changes in Norrie Disease Patients with an X‐Chromosomal Deletion Affecting Monoamine Oxidase
D. Murphy, K. Sims, F. Karoum, A. Chapelle +3 more
1990Journal of Neurochemistry51 citations
Semantic Scholar
Low-dose apomorphine reduces serum homovanillic acid concentrations in schizophrenic patients.
N. Cutler, D. V. Jeste, F. Karoum, R. J. Wyatt
1982Life Science51 citations
Semantic Scholar
Fluctuating high urinary phenylethylamine excretion rates in some bipolar affective disorder patients.
F. Karoum, M. Linnoila, W. Potter, L. Chuang +2 more
1982Psychiatry Research46 citations
Semantic Scholar
Absence of 6‐Hydroxydopamine in the Rat Brain After Treatment with Stimulants and Other Dopaminergic Agents: A Mass Fragmentographic Study
F. Karoum, Stanislaw J. Chrapusta, M. F. Egan, R. J. Wyatt
1993Journal of Neurochemistry43 citations
Semantic Scholar
Biochemical evidence for uncrossed and crossed locus coeruleus projections to the spinal cord.
F. Karoum, J. Commissiong, N. Neff, R. Wyatt
1980Brain Research43 citations
Semantic Scholar
Seasonal variation in human central dopamine activity.
C. Karson, K. Berman, J. Kleinman, F. Karoum
1984Psychiatry Research42 citations
Semantic Scholar
Phenylacetic acid excretion in schizophrenia and depression: the origins of PAA in man.
F. Karoum, S. Potkin, Lin-Whei Chuang, D. L. Murphy +2 more
1984Biological Psychiatry39 citations
Semantic Scholar
Clinical studies on norepinephrine metabolism: how to interpret the numbers.
M. Linnoila, S. Guthrie, E. Lane, F. Karoum +2 more
1986Psychiatry Research38 citations
Semantic Scholar
Cyclobenzaprine: a possible mechanism of action for its muscle relaxant effect.
J. Commissiong, F. Karoum, Rhoderic J. Reiffenstein, N. Neff
1981Canadian Journal of Physiology and Pharmacology37 citations
Semantic Scholar
Decreased DOPAC in the anterior cingulate cortex of individuals with schizophrenia.
R. Wyatt, F. Karoum, M. Casanova
1995Biological Psychiatry36 citations
Semantic Scholar
Plasma phenylethylamine and phenylalanine in chronic schizophrenic patients.
H. V. Szymanski, E. Naylor, F. Karoum
1987Biological Psychiatry32 citations
Semantic Scholar
Selective effects of phenylethylamine on central catecholamines: a comparative study with amphetamine.
F. Karoum, S. Speciale, Lin-Whei Chuang, R. J. Wyatt
1982Journal of Pharmacology and Experimental Therapeutics32 citations
Semantic Scholar
CATECHOLAMINES AND METABOLITES IN THE BRAINS OF PSYCHOTICS AND NORMALS: POST-MORTEM STUDIES
J. Kleinman, P. Bridge, F. Karoum, S. Speciale +4 more
197932 citations
Semantic Scholar
Effects of acute and chronic clozapine and haloperidol administration on 3-methoxytyramine accumulation in rat prefrontal cortex, nucleus accumbens and striatum.
M. F. Egan, F. Karoum, R. J. Wyatt
1991European Journal of Pharmacology30 citations
Semantic Scholar
Biochemical effects of L-deprenyl in atypical depressives.
M. Liebowitz, F. Karoum, F. Quitkin, S. Davies +3 more
1985Biological Psychiatry30 citations
Semantic Scholar
Suicidal behavior in depression: relationship to noradrenergic function.
A. Roy, D. Pickar, J. de Jong, F. Karoum +1 more
1989Biological Psychiatry29 citations
Semantic Scholar
Cross-cultural study of a biochemical abnormality in paranoid schizophrenia.
D. Jeste, D. R. Doongaji, Dilkhush Panjwani, M. Datta +6 more
1981Psychiatry Research29 citations
Semantic Scholar
POSTMORTEM NEUROCHEMICAL STUDIES IN CHRONIC SCHIZOPHRENIA
J. Kleinman, F. Karoum, J. Rosenblatt, Gillin Jc +6 more
198228 citations
Semantic Scholar
Clinical and laboratory studies with selective monoamine-oxidase-inhibiting drugs. Implications for hypothesized neurotransmitter changes associated with depression and antidepressant drug effects.
D. Murphy, R. Cohen, L. J. Siever, B. F. Roy +4 more
1983Modern problems of pharmacopsychiatry27 citations
Semantic Scholar
Central catecholamines, cognitive impairment, and affective state in elderly schizophrenics and controls.
T. Bridge, J. Kleinman, B. Soldo, F. Karoum
1987Biological Psychiatry26 citations
Semantic Scholar
Phenylethylamine excretion in depression.
L. DeLisi, D. Murphy, F. Karoum, E. Mueller +2 more
1984Psychiatry Research26 citations
Semantic Scholar
D-dopa and L-dopa similarly elevate brain dopamine and produce turning behavior in rats.
F. Karoum, W. Freed, Lin-Whei Chuang, E. Cannon-Spoor +2 more
1988Brain Research22 citations
Semantic Scholar
Postmortem central catecholamines and antemortem cognitive impairment in elderly schizophrenics and controls.
T. Bridge, J. Kleinman, F. Karoum, R. Wyatt
1985Neuropsychobiology22 citations
Semantic Scholar
Dorsal hippocampal lesion does not affect dopaminergic indices in the basal ganglia.
B. Lipska, G. Jaskiw, F. Karoum, I. Phillips +2 more
1991Pharmacology, Biochemistry and Behavior21 citations
Semantic Scholar
Low-dose apomorphine and bromocriptine in neuroleptic-induced movement disorders.
D. Jeste, N. Cutler, C. Kaufmann, F. Karoum
1983Biological Psychiatry21 citations
Semantic Scholar
Different effects of amphetamine and amfonelic acid on peripheral and central catecholamine metabolism.
Samuel G. Speciale, F. Karoum, R. J. Wyatt
1980European Journal of Pharmacology21 citations
Semantic Scholar
Deficient Dopamine Metabolism in the Celiac Ganglion of Spontaneously Hypertensive Rats
B. Lutold, F. Karoum, N. Neff
1979Circulation Research21 citations Open access
Semantic Scholar
Effect of chlordecone (Kepone) on the rat brain concentration of 3-methoxy-4-hydroxyphenylglycol: evidence for a possible involvement of the norepinephrine system in chlordecone-induced tremor.
P.-H. Chen, H. A. Tilson, G. D. Marbury, F. Karoum +1 more
1985Toxicology and Applied Pharmacology20 citations
Semantic Scholar
Central and peripheral effects of iminodipropionitrile on catecholamine metabolism in rats
J. Cadet, F. Karoum
1988Synapse19 citations
Semantic Scholar
The Genain Quadruplets 25 years later: a diagnostic and biochemical followup.
L. DeLisi, A. Mirsky, M. Buchsbaum, D. V. van Kammen +11 more
1984Psychiatry Research19 citations
Semantic Scholar
Low dose bromocriptine: a study of acute effects in chronic mediated schizophrenics.
N. Cutler, D. Jeste, C. Kaufmann, F. Karoum +2 more
1984Progress in Neuro-psychopharmacology and Biological Psychiatry18 citations
Semantic Scholar
Common mechanism of action of biochemically "specific" antidepressants.
W. Potter, F. Karoum, M. Linnoila
1984Progress in Neuro-psychopharmacology and Biological Psychiatry16 citations
Semantic Scholar
Differences in lithium effects in depressed and healthy subjects
M. Rudorfer, F. Karoum, Richard J. Ross, William Z. Potter +1 more
1985Clinical pharmacology and therapy15 citations
Semantic Scholar
Biochemical indices of the effects of the selective MAO inhibitors clorgyline, pargyline and deprenyl in man
D. Murphy, D. Pickar, D. Jimerson, R. Cohen +3 more
198115 citations
Semantic Scholar
Biochemical and Pharmacological Characteristics of Conjugated Catecholamines in the Rat Brain
F. Karoum, Lin-Whei Chuang, R. J. Wyatt
1983Journal of Neurochemistry14 citations
Semantic Scholar

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Lin-Whei Chuang

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