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Barbara Chiavarina · SciRah

Researcher profile · Semantic Scholar

Barbara Chiavarina

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Barbara Chiavarina — researcher profile on SciRah

h-index: 27
Works: 43
Citations: 4,385

Most-cited papers

Ketones and lactate “fuel” tumor growth and metastasis
G. Bonuccelli, Aristotelis Tsirigos, D. Whitaker-Menezes, S. Pavlides +8 more
2010Cell Cycle596 citations Open access
Semantic Scholar
Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution
U. Martinez-Outschoorn, Renee M. Balliet, Dayana B. Rivadeneira, Barbara Chiavarina +12 more
2010Cell Cycle465 citations Open access
Semantic Scholar
Autophagy in cancer associated fibroblasts promotes tumor cell survival
U. Martinez-Outschoorn, C. Trimmer, Zhao Lin, D. Whitaker-Menezes +13 more
2010Cell Cycle418 citations Open access
Semantic Scholar
The autophagic tumor stroma model of cancer
S. Pavlides, Aristotelis Tsirigos, G. Migneco, D. Whitaker-Menezes +10 more
2010Cell Cycle253 citations Open access
Semantic Scholar
Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: Implications for breast cancer and DCIS therapy with autophagy inhibitors
U. Martinez-Outschoorn, S. Pavlides, D. Whitaker-Menezes, Kristin M. Daumer +10 more
2010Cell Cycle249 citations Open access
Semantic Scholar
The reverse Warburg Effect: Glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts
G. Bonuccelli, D. Whitaker-Menezes, Remedios Castelló-Cros, S. Pavlides +12 more
2010Cell Cycle233 citations Open access
Semantic Scholar
HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells
Barbara Chiavarina, D. Whitaker-Menezes, G. Migneco, U. Martinez-Outschoorn +10 more
2010Cell Cycle225 citations Open access
Semantic Scholar
CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, “fueling” tumor growth via paracrine interactions, without an increase in neo-angiogenesis
Claudia Capparelli, Barbara Chiavarina, D. Whitaker-Menezes, Timothy G. Pestell +7 more
2012Cell Cycle222 citations Open access
Semantic Scholar
Understanding the "lethal" drivers of tumor-stroma co-evolution
M. Lisanti, U. Martinez-Outschoorn, Barbara Chiavarina, S. Pavlides +7 more
2010Cancer Biology & Therapy204 citations Open access
Semantic Scholar
The autophagic tumor stroma model of cancer or “battery-operated tumor growth”
U. Martinez-Outschoorn, D. Whitaker-Menezes, S. Pavlides, Barbara Chiavarina +15 more
2010Cell Cycle172 citations Open access
Semantic Scholar
Glycolytic cancer associated fibroblasts promote breast cancer tumor growth, without a measurable increase in angiogenesis: Evidence for stromal-epithelial metabolic coupling
G. Migneco, D. Whitaker-Menezes, Barbara Chiavarina, Remedios Castelló-Cros +9 more
2010Cell Cycle164 citations Open access
Semantic Scholar
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis
M. Nokin, F. Durieux, P. Peixoto, Barbara Chiavarina +21 more
2016eLife120 citations Open access
Semantic Scholar
Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth
Barbara Chiavarina, D. Whitaker-Menezes, U. Martinez-Outschoorn, A. Witkiewicz +7 more
2011Cancer Biology & Therapy118 citations Open access
Semantic Scholar
Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth
Renee M. Balliet, Claudia Capparelli, Carmela Guido, Timothy G. Pestell +8 more
2011Cell Cycle103 citations Open access
Semantic Scholar
Diabetes Impairs the Vascular Recruitment of Normal Stem Cells by Oxidant Damage, Reversed by Increases in pAMPK, Heme Oxygenase-1, and Adiponectin
G. Sambuceti, S. Morbelli, L. Vanella, C. Kusmic +11 more
2009Stem Cells84 citations Open access
Semantic Scholar
Endothelial colony-forming cells from patients with chronic myeloproliferative disorders lack the disease-specific molecular clonality marker.
G. Piaggio, V. Rosti, M. Corselli, F. Bertolotti +18 more
2009Blood82 citations
Semantic Scholar
Metabolic reprogramming and two-compartment tumor metabolism
Barbara Chiavarina, U. Martinez-Outschoorn, D. Whitaker-Menezes, A. Howell +4 more
2012Cell Cycle76 citations Open access
Semantic Scholar
Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis
Barbara Chiavarina, B. Costanza, Roberto Ronca, A. Blomme +22 more
2021Theranostics67 citations Open access
Semantic Scholar
Mechanistic insights into the synergistic activation of the RXR–PXR heterodimer by endocrine disruptor mixtures
V. Delfosse, T. Huet, D. Harrus, M. Granell +13 more
2020Proceedings of the National Academy of Sciences of the United States of America65 citations Open access
Semantic Scholar
Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer
Barbara Chiavarina, M. Nokin, J. Bellier, F. Durieux +14 more
2017International Journal of Molecular Sciences62 citations Open access
Semantic Scholar
Mesenchymal Stem Cells Protective Effect in Adriamycin Model of Nephropathy
A. Magnasco, M. Corselli, R. Bertelli, A. Ibatici +9 more
2008Cell Transplantation58 citations
Semantic Scholar
Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes
Barbara Chiavarina, M. Nokin, F. Durieux, E. Bianchi +9 more
2014OncoTarget57 citations Open access
Semantic Scholar
Interspecies Differences in Activation of Peroxisome Proliferator-Activated Receptor γ by Pharmaceutical and Environmental Chemicals.
Clémentine Garoche, A. Boulahtouf, M. Grimaldi, Barbara Chiavarina +5 more
2021Environmental Science and Technology56 citations Open access
Semantic Scholar
Fibroblast-derived prolargin is a tumor suppressor in hepatocellular carcinoma
Barbara Chiavarina, Roberto Ronca, Yukihiro Otaka, R. Sutton +17 more
2022Oncogene37 citations
Semantic Scholar
Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab.
J. Bellier, M. Nokin, M. Caprasse, Assia Tiamiou +20 more
2020Cell Reports33 citations Open access
Semantic Scholar
Inhibition of cell proliferation, cytotoxicity and induction of apoptosis of 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene in gastrointestinal tumour cell lines and preliminary evaluation of its toxicity in vivo.
C. Dell'erba, Barbara Chiavarina, C. Fenoglio, G. Petrillo +7 more
2005Pharmacological Research29 citations
Semantic Scholar
Morphological and histochemical evidence of the protective effect of procainamide hydrochloride on tissue damage induced by repeated administration of low doses of cisplatin.
C. Fenoglio, E. Boncompagni, Barbara Chiavarina, S. Cafaggi +2 more
2005Anticancer Research27 citations
Semantic Scholar
The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor
N. Creusot, M. Gassiot, Elina Alaterre, Barbara Chiavarina +11 more
2020Cells24 citations Open access
Semantic Scholar
Preliminary evaluation in vitro of the inhibition of cell proliferation, cytotoxicity and induction of apoptosis by 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene
M. Viale, M. Mariggiò, Massimo Ottone, Barbara Chiavarina +5 more
2004Investigational new drugs18 citations
Semantic Scholar
The PTX3/TLR4 autocrine loop as a novel therapeutic target in triple negative breast cancer
Arianna Giacomini, Marta Turati, E. Grillo, S. Rezzola +14 more
2023Experimental Hematology & Oncology13 citations Open access
Semantic Scholar
A Comparative Study of Human and Zebrafish Pregnane X Receptor Activities of Pesticides and Steroids Using In Vitro Reporter Gene Assays
N. Creusot, Clémentine Garoche, M. Grimaldi, A. Boulahtouf +3 more
2021Frontiers in Endocrinology13 citations Open access
Semantic Scholar
Study of feasibility of the treatment with procainamide hydrochloride and cisplatin in pregnant mice.
E. Ognio, Barbara Chiavarina, M. Peterka, M. Mariggiò +1 more
2006Chemico-Biological Interactions13 citations
Semantic Scholar
1,4-Bis(1-naphthyl)-2,3-dinitro-1,3-butadiene a novel anticancer compound effective against tumor cell lines characterized by different mechanisms of resistance.
M. Novi, Massimo Ottone, C. Dell'erba, F. Barbieri +3 more
2004Oncology Report13 citations
Semantic Scholar
Collaborative and Defensive Fibroblasts in Tumor Progression and Therapy Resistance.
Barbara Chiavarina, A. Turtoi
2017Current Medicinal Chemistry11 citations
Semantic Scholar
Author response: Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis
M. Nokin, F. Durieux, P. Peixoto, Barbara Chiavarina +21 more
20163 citations Open access
Semantic Scholar
Transplacental passage of Pt after treatment with the new triamine complex cis-diaminechloro-[2-(diethylamino) ethyl 4-amino-benzoate, N4]-chloride platinum (II) monohydrochloride monohydrate
E. Ognio, Barbara Chiavarina, G. Caviglioli, Maddalena Lapide +1 more
2004Archives of Toxicology3 citations
Semantic Scholar
Correction: Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis
M. Nokin, F. Durieux, Paul Peixoto, Barbara Chiavarina +21 more
2024eLife1 citations Open access
Semantic Scholar
Methylglyoxal Scavengers Resensitize KRAS-Mutated Colorectal Tumors to Cetuximab.
J. Bellier, M. Nokin, M. Caprasse, Assia Tiamiou +20 more
2026Cell Reports0 citations
Semantic Scholar
Tumor-Antagonizing Fibroblasts Secrete Prolargin as Tumor Suppressor in Hepatocellular Carcinoma
Barbara Chiavarina, Roberto Ronca, Yukihiro Otaka, R B Sutton +14 more
2021bioRxiv0 citations Open access
Semantic Scholar
Accumulation of methylglyoxal, a glycolysis by-product modulates YAP1 transcription co-factor localization and activity in human breast cancer cells through HSP90 modification
M. Nokin, F. Durieux, P. Peixoto, Barbara Chiavarina +9 more
20150 citations
Semantic Scholar
Triple negative human breast cancers accumulate significantly less Arg‐pyrimidine moieties, than other subtype lesions (58.3)
V. Castronovo, Barbara Chiavarina, M. Nokin, F. Durieux +5 more
20140 citations
Semantic Scholar
Brief report Endothelial colony-forming cells from patients with chronic myeloproliferative disorders lack the disease-speciﬁc molecular clonality marker
G. Piaggio, V. Rosti, M. Corselli, F. Bertolotti +18 more
20090 citations
Semantic Scholar
Valutazione della tossicità e dell’attività antitumorale in vivo dell’1,4-bis(1-naftil)-2,3-dinitro-1,3-butadiene.
Maurizio Viale, Barbara Chiavarina, C. Dell'erba, C. Fenoglio +5 more
20050 citations
Semantic Scholar

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