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D. Bexell · SciRah

Researcher profile · Semantic Scholar

D. Bexell

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D. Bexell — researcher profile on SciRah

h-index: 26
Works: 80
Citations: 2,521

Most-cited papers

Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer.
C. Wigerup, S. Påhlman, D. Bexell
2016Pharmacology and Therapeutics627 citations Open access
Semantic Scholar
Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas.
D. Bexell, Salina Gunnarsson, Ariane Tormin, A. Darabi +4 more
2009Molecular Therapy266 citations Open access
Semantic Scholar
Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers
R. Allaoui, C. Bergenfelz, S. Mohlin, C. Hagerling +11 more
2016Nature Communications167 citations Open access
Semantic Scholar
Toward brain tumor gene therapy using multipotent mesenchymal stromal cell vectors.
D. Bexell, S. Scheding, J. Bengzon
2010Molecular Therapy102 citations Open access
Semantic Scholar
Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours
Noémie Braekeveldt, C. Wigerup, D. Gisselsson, S. Mohlin +12 more
2014International Journal of Cancer101 citations Open access
Semantic Scholar
PI3K-mTORC2 but not PI3K-mTORC1 regulates transcription of HIF2A/EPAS1 and vascularization in neuroblastoma.
S. Mohlin, A. Hamidian, Kristoffer von Stedingk, E. Bridges +3 more
2015Cancer Research97 citations Open access
Semantic Scholar
Stem cell-based therapy for malignant glioma.
D. Bexell, A. Svensson, J. Bengzon
2013Cancer Treatment Reviews77 citations Open access
Semantic Scholar
Four evolutionary trajectories underlie genetic intratumoral variation in childhood cancer
J. Karlsson, Anders Valind, Linda Holmquist Mengelbier, Sofia Bredin +16 more
2018Nature Genetics74 citations
Semantic Scholar
Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer
L. H. Mengelbier, J. Karlsson, D. Lindgren, Anders Valind +19 more
2015Nature Communications73 citations Open access
Semantic Scholar
Intratumoral IL-7 delivery by mesenchymal stromal cells potentiates IFNgamma-transduced tumor cell immunotherapy of experimental glioma.
Salina Gunnarsson, D. Bexell, A. Svensson, P. Siesjö +2 more
2010Journal of Neuroimmunology66 citations
Semantic Scholar
Integrative discovery of treatments for high-risk neuroblastoma
Elin Almstedt, R. Elgendy, Neda Hekmati, Emil Rosén +14 more
2020Nature Communications58 citations Open access
Semantic Scholar
Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma.
Noémie Braekeveldt, Kristoffer von Stedingk, S. Fransson, Ángela Martínez-Monleón +18 more
2018Cancer Research50 citations Open access
Semantic Scholar
Patient-derived xenografts as preclinical neuroblastoma models
Noémie Braekeveldt, D. Bexell
2017Cell and Tissue Research50 citations Open access
Semantic Scholar
Neuroblastoma patient-derived orthotopic xenografts reflect the microenvironmental hallmarks of aggressive patient tumours.
Noémie Braekeveldt, C. Wigerup, I. Tadéo, Siv Beckman +12 more
2016Cancer Letters44 citations Open access
Semantic Scholar
CD133+ and nestin+ tumor‐initiating cells dominate in N29 and N32 experimental gliomas
D. Bexell, Salina Gunnarsson, P. Siesjö, J. Bengzon +1 more
2009International Journal of Cancer43 citations Open access
Semantic Scholar
Inhibition of fatty acid synthesis induces differentiation and reduces tumor burden in childhood neuroblastoma
M. V. Ruiz-Pérez, Lourdes Sainero-Alcolado, G. Oliynyk, Isabell Matuschek +11 more
2021iScience40 citations Open access
Semantic Scholar
Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance
Adriana Mañas, K. Aaltonen, Natalie Andersson, K. Hansson +12 more
2022bioRxiv38 citations Open access
Semantic Scholar
Neuroblastoma patient-derived xenograft cells cultured in stem-cell promoting medium retain tumorigenic and metastatic capacities but differentiate in serum
C. Persson, Kristoffer von Stedingk, D. Bexell, My Merselius +5 more
2017Scientific Reports37 citations Open access
Semantic Scholar
Anti‐tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL‐302 in neuroblastoma
S. Mohlin, K. Hansson, Katarzyna Radke, Sonia Martínez +8 more
2019EMBO Molecular Medicine36 citations Open access
Semantic Scholar
ARNT-dependent HIF-2 transcriptional activity is not sufficient to regulate downstream target genes in neuroblastoma.
C. Persson, Kristoffer von Stedingk, Elina Fredlund, D. Bexell +3 more
2020Experimental Cell Research32 citations Open access
Semantic Scholar
Human G-MDSCs are neutrophils at distinct maturation stages promoting tumor growth in breast cancer
Meliha Mehmeti-Ajradini, C. Bergenfelz, A. Larsson, Robert Carlsson +17 more
2020Life Science Alliance32 citations Open access
Semantic Scholar
The Iroquois homeobox proteins IRX3 and IRX5 have distinct roles in Wilms tumour development and human nephrogenesis
Linda Holmquist Mengelbier, Simon Lindell-Munther, Hiroaki Yasui, Caroline Jansson +7 more
2018Journal of Pathology32 citations Open access
Semantic Scholar
Breast cancer associated CD169+ macrophages possess broad immunosuppressive functions but enhance antibody secretion by activated B cells
Fríða Björk Gunnarsdóttir, Oscar Briem, A. Lindgren, E. Källberg +11 more
2023Frontiers in Immunology30 citations Open access
Semantic Scholar
Rat multipotent mesenchymal stromal cells lack long-distance tropism to 3 different rat glioma models.
D. Bexell, Salina Gunnarsson, A. Svensson, Ariane Tormin +6 more
2012Neurosurgery29 citations
Semantic Scholar
Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis
A. Grigoryan, D. Zacharaki, A. Balhuizen, C. Côme +20 more
2022Science Translational Medicine27 citations Open access
Semantic Scholar
Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma
K. Hansson, Katarzyna Radke, K. Aaltonen, J. Saarela +8 more
2020Science Translational Medicine27 citations Open access
Semantic Scholar
Engineered human mesenchymal stem cells for neuroblastoma therapeutics
V. Nieddu, R. Piredda, D. Bexell, Jack Barton +6 more
2019Oncology Report25 citations Open access
Semantic Scholar
Characterization of the subventricular zone neurogenic response to rat malignant brain tumors.
D. Bexell, Salina Gunnarsson, J. Nordquist, J. Bengzon
2007Neuroscience24 citations
Semantic Scholar
ALK positively regulates MYCN activity through repression of HBP1 expression
Shana Claeys, G. Denecker, K. Durinck, Bieke Decaesteker +24 more
2018Oncogene22 citations Open access
Semantic Scholar
The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness
Liselot M. Mus, I. Lambertz, Shana Claeys, C. Kumps +16 more
2020Scientific Reports21 citations Open access
Semantic Scholar
Patient-derived models: Advanced tools for precision medicine in neuroblastoma
K. Aaltonen, Katarzyna Radke, A. Adamska, Alexandra Seger +2 more
2023Frontiers in Oncology15 citations Open access
Semantic Scholar
Macrophage infiltration promotes regrowth in MYCN-amplified neuroblastoma after chemotherapy
Anders Valind, B. M. Verhoeven, J. Enoksson, J. Karlsson +8 more
2023Oncoimmunology14 citations Open access
Semantic Scholar
Anti-tumor effects of rigosertib in high-risk neuroblastoma
Katarzyna Radke, K. Hansson, J. Sjölund, Magdalena Wolska +6 more
2021Translational Oncology13 citations Open access
Semantic Scholar
Orthotopic Wilms tumor xenografts derived from cell lines reflect limited aspects of tumor morphology and clinical characteristics
Linda Holmquist Mengelbier, D. Bexell, Daniel Sehic, Cristina D. Ciornei +1 more
2014Pediatric Blood & Cancer13 citations
Semantic Scholar
Influence of Coronary Artery Stenosis Severity and Coronary Collateralization on Extent of Chronic Myocardial Scar: Insights from Quantitative Coronary Angiography and Delayed-Enhancement MRI
D. Bexell, R. Setser, P. Schoenhagen, M. Lieber +8 more
2008Open Cardiovascular Medicine Journal12 citations Open access
Semantic Scholar
Label-free separation of neuroblastoma patient-derived xenograft (PDX) cells from hematopoietic progenitor cell products by acoustophoresis
F. Olm, Lena Panse, J. Dykes, D. Bexell +2 more
2021Stem cell research & therapeutics11 citations Open access
Semantic Scholar
Multidimensional intratumour heterogeneity in neuroblastoma
Kristoffer von Stedingk, D. Gisselsson, D. Bexell
2019OncoTarget11 citations Open access
Semantic Scholar
PI 3 K-mTORC 2 but not PI 3 K-mTORC 1 regulates transcription of HIF 2 A / EPAS 1 and vascularization in neuroblastoma
S. Mohlin, A. Hamidian, Kristoffer von Stedingk, E. Bridges +3 more
201511 citations
Semantic Scholar
Immunizations With IFNγ Secreting Tumor Cells can Eliminate Fully Established and Invasive Rat Gliomas
S. Janelidze, D. Bexell, Wiaam Badn, A. Darabi +8 more
2009Journal of immunotherapy11 citations
Semantic Scholar
Targeted ferroptosis induction enhances chemotherapy efficacy in chemoresistant neuroblastoma
Adriana Mañas, Alexandra Seger, Aleksandra Adamska, Kyriaki Smyrilli +7 more
2025npj Precision Oncology10 citations Open access
Semantic Scholar
An immature subset of neuroblastoma cells synthesizes retinoic acid and depends on this metabolite
Tim van Groningen, Camilla U. Niklasson, A. Chan, Nurdan Akogul +20 more
2021bioRxiv9 citations Open access
Semantic Scholar
Inflammatory macrophage derived TNFα downregulates estrogen receptor α via FOXO3a inactivation in human breast cancer cells.
Fríða Björk Gunnarsdóttir, C. Hagerling, C. Bergenfelz, Meliha Mehmeti +8 more
2020Experimental Cell Research9 citations Open access
Semantic Scholar
Intratumorally implanted mesenchymal stromal cells potentiate peripheral immunotherapy against malignant rat gliomas.
Salina Ströjby, Sofia Eberstål, A. Svensson, S. Fritzell +4 more
2014Journal of Neuroimmunology9 citations
Semantic Scholar
Early evolutionary branching across spatial domains predisposes to clonal replacement under chemotherapy in neuroblastoma
Jenny Karlsson, Hiroaki Yasui, Adriana Mañas, Natalie Andersson +14 more
2024Nature Communications8 citations Open access
Semantic Scholar
Anti‐tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL‐302 in neuroblastoma
S. Mohlin, K. Hansson, Katarzyna Radke, Sonia Martínez +8 more
2020EMBO Molecular Medicine8 citations Open access
Semantic Scholar
Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma
Emma Lindell, Jing Guo, Miao Zhao, N. Rameika +12 more
2025Cell Death and Disease4 citations Open access
Semantic Scholar
Evolutionary unpredictability in cancer model systems
S. Chattopadhyay, J. Karlsson, Michele Ferro, Adriana Mañas +13 more
2022bioRxiv3 citations Open access
Semantic Scholar
Patient-derived xenografts as preclinical neuroblastoma models
Noémie Braekeveldt, D. Bexell
2017Cell and Tissue Research3 citations Open access
Semantic Scholar
Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma
Katarzyna Radke, K. Aaltonen, E. A. Muciño-Olmos, Javanshir Esfandyari +22 more
2025EMBO Molecular Medicine2 citations Open access
Semantic Scholar
Discovery of epi-Enprioline as a Novel Drug for the Treatment of Vincristine Resistant Neuroblastoma
Wondossen Sime, Mohamed Jemaà, Yasmin Abassi, V. A. Lasorsa +8 more
2020International Journal of Molecular Sciences1 citations Open access
Semantic Scholar

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