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S. Påhlman · SciRah

Researcher profile · Semantic Scholar

S. Påhlman

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S. Påhlman — researcher profile on SciRah

h-index: 56
Works: 186
Citations: 11K

Most-cited papers

Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer.
C. Wigerup, S. Påhlman, D. Bexell
2016Pharmacology and Therapeutics627 citations Open access
Semantic Scholar
Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments
Xiao-Nan Zhang, M. Fryknäs, E. Hernlund, Walid Fayad +12 more
2014Nature Communications245 citations Open access
Semantic Scholar
MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells
Hanna Zirath, A. Frenzel, G. Oliynyk, L. Segerström +10 more
2013Proceedings of the National Academy of Sciences of the United States of America235 citations Open access
Semantic Scholar
Cancer cell differentiation heterogeneity and aggressive behavior in solid tumors
A. Jögi, M. Vaapil, M. Johansson, S. Påhlman
2012Upsala Journal of Medical Sciences205 citations Open access
Semantic Scholar
High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastoma
E. Fredlund, M. Ringnér, J. Maris, S. Påhlman
2008Proceedings of the National Academy of Sciences of the United States of America174 citations Open access
Semantic Scholar
Cancer-associated fibroblast-secreted CXCL16 attracts monocytes to promote stroma activation in triple-negative breast cancers
R. Allaoui, C. Bergenfelz, S. Mohlin, C. Hagerling +11 more
2016Nature Communications167 citations Open access
Semantic Scholar
MYCN-regulated microRNAs repress estrogen receptor-α (ESR1) expression and neuronal differentiation in human neuroblastoma
Jakob Lovén, Nikolay Zinin, T. Wahlström, I. Müller +6 more
2010Proceedings of the National Academy of Sciences of the United States of America151 citations Open access
Semantic Scholar
HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells
Alexander Pietras, L. Hansford, A. Johnsson, E. Bridges +10 more
2009Proceedings of the National Academy of Sciences of the United States of America128 citations Open access
Semantic Scholar
Hypoxia-inducible factor-2alpha correlates to distant recurrence and poor outcome in invasive breast cancer.
Karolina Helczynska, A. Larsson, Linda Holmquist Mengelbier, E. Bridges +5 more
2008Cancer Research127 citations Open access
Semantic Scholar
Neuroblastoma as an experimental model for neuronal differentiation and hypoxia-induced tumor cell dedifferentiation.
A. Edsjö, Linda Holmquist, S. Påhlman
2007Seminars in Cancer Biology125 citations
Semantic Scholar
Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours
Noémie Braekeveldt, C. Wigerup, D. Gisselsson, S. Mohlin +12 more
2014International Journal of Cancer101 citations Open access
Semantic Scholar
PI3K-mTORC2 but not PI3K-mTORC1 regulates transcription of HIF2A/EPAS1 and vascularization in neuroblastoma.
S. Mohlin, A. Hamidian, Kristoffer von Stedingk, E. Bridges +3 more
2015Cancer Research97 citations Open access
Semantic Scholar
Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer
A. Jögi, D. Brennan, L. Rydén, Kristina Magnusson +8 more
2009Modern Pathology93 citations Open access
Semantic Scholar
Correction: Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes
K. De Preter, J. Vandesompele, P. Heimann, N. Yigit +10 more
2007Genome Biology90 citations Open access
Semantic Scholar
Stem cell factor induces HIF-1alpha at normoxia in hematopoietic cells.
M. Pedersen, Tobias Löfstedt, Jian-Min Sun, Linda Holmquist-Mengelbier +2 more
2008Biochemical and Biophysical Research Communications - BBRC80 citations
Semantic Scholar
Hypoxia and hypoxia-inducible factors in neuroblastoma
S. Påhlman, S. Mohlin
2017Cell and Tissue Research79 citations Open access
Semantic Scholar
JAG2 Induction in Hypoxic Tumor Cells Alters Notch Signaling and Enhances Endothelial Cell Tube Formation
Alexander Pietras, Kristoffer von Stedingk, D. Lindgren, S. Påhlman +1 more
2011Molecular Cancer Research76 citations Open access
Semantic Scholar
HIF-1α and HIF-2α Are Differentially Regulated In vivo in Neuroblastoma: High HIF-1α Correlates Negatively to Advanced Clinical Stage and Tumor Vascularization
R. Noguera, E. Fredlund, M. Piqueras, Alexander Pietras +3 more
2009Clinical Cancer Research70 citations Open access
Semantic Scholar
The HIF-2α-driven pseudo-hypoxic phenotype in tumor aggressiveness, differentiation, and vascularization.
Alexander Pietras, A. Johnsson, S. Påhlman
2010Current Topics in Microbiology and Immunology61 citations Open access
Semantic Scholar
Extracellular matrix composition defines an ultra-high-risk group of neuroblastoma within the high-risk patient cohort
I. Tadéo, Ana P. Berbegall, V. Castel, P. García-Miguel +4 more
2016British Journal of Cancer60 citations Open access
Semantic Scholar
Integrative discovery of treatments for high-risk neuroblastoma
Elin Almstedt, R. Elgendy, Neda Hekmati, Emil Rosén +14 more
2020Nature Communications58 citations Open access
Semantic Scholar
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer
Barbara Hjelm, D. Brennan, Nooreldin Zendehrokh, J. Eberhard +11 more
2011PROTEOMICS - Clinical Applications56 citations
Semantic Scholar
Hypoxia-mediated induction of the polyamine system provides opportunities for tumor growth inhibition by combined targeting of vascular endothelial growth factor and ornithine decarboxylase.
Katrin J. Svensson, Johanna E. Welch, P. Kucharzewska, P. Bengtson +5 more
2008Cancer Research56 citations Open access
Semantic Scholar
HIF2A and IGF2 expression correlates in human neuroblastoma cells and normal immature sympathetic neuroblasts.
S. Mohlin, A. Hamidian, S. Påhlman
2013Neoplasia54 citations Open access
Semantic Scholar
Binomial Mitotic Segregation of MYCN-Carrying Double Minutes in Neuroblastoma Illustrates the Role of Randomness in Oncogene Amplification
Gisela Lundberg, A. Rosengren, U. Håkanson, Henrik Stewenius +4 more
2008PLoS ONE52 citations Open access
Semantic Scholar
Patient-Derived Xenograft Models Reveal Intratumor Heterogeneity and Temporal Stability in Neuroblastoma.
Noémie Braekeveldt, Kristoffer von Stedingk, S. Fransson, Ángela Martínez-Monleón +18 more
2018Cancer Research50 citations Open access
Semantic Scholar
Hypoxia, pseudohypoxia and cellular differentiation.
S. Mohlin, C. Wigerup, A. Jögi, S. Påhlman
2017Experimental Cell Research49 citations
Semantic Scholar
Refined control of cell stemness allowed animal evolution in the oxic realm
E. Hammarlund, Kristoffer von Stedingk, S. Påhlman
2018Nature Ecology & Evolution46 citations Open access
Semantic Scholar
Neuroblastoma patient-derived orthotopic xenografts reflect the microenvironmental hallmarks of aggressive patient tumours.
Noémie Braekeveldt, C. Wigerup, I. Tadéo, Siv Beckman +12 more
2016Cancer Letters44 citations Open access
Semantic Scholar
Quantitative proteomics profiling of primary lung adenocarcinoma tumors reveals functional perturbations in tumor metabolism.
M. Pernemalm, L. De Petris, R. Branca, J. Forshed +10 more
2013Journal of Proteome Research43 citations Open access
Semantic Scholar
Neuroblastoma aggressiveness in relation to sympathetic neuronal differentiation stage.
S. Mohlin, C. Wigerup, S. Påhlman
2011Seminars in Cancer Biology39 citations Open access
Semantic Scholar
Neuroblastoma patient-derived xenograft cells cultured in stem-cell promoting medium retain tumorigenic and metastatic capacities but differentiate in serum
C. Persson, Kristoffer von Stedingk, D. Bexell, My Merselius +5 more
2017Scientific Reports37 citations Open access
Semantic Scholar
Hypoxic Conditions Induce a Cancer-Like Phenotype in Human Breast Epithelial Cells
M. Vaapil, Karolina Helczynska, René Villadsen, O. Petersen +5 more
2012PLoS ONE37 citations Open access
Semantic Scholar
Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells
Helen M. Pettersson, Alexander Pietras, Matilda Munksgaard Persson, J. Karlsson +3 more
2009Molecular Cancer Therapeutics37 citations Open access
Semantic Scholar
Differential regulation of HIF-1α and HIF-2α in neuroblastoma: Estrogen-related receptor alpha (ERRα) regulates HIF2A transcription and correlates to poor outcome.
A. Hamidian, Kristoffer von Stedingk, Matilda Munksgaard Thorén, S. Mohlin +1 more
2015Biochemical and Biophysical Research Communications - BBRC34 citations Open access
Semantic Scholar
The tyrosine kinase CSK associates with FLT3 and c-Kit receptors and regulates downstream signaling.
Julhash U. Kazi, M. Vaapil, S. Agarwal, E. Bracco +2 more
2013Cellular Signalling34 citations Open access
Semantic Scholar
A Novel Topical PPARγ Agonist Induces PPARγ Activity in Ulcerative Colitis Mucosa and Prevents and Reverses Inflammation in Induced Colitis Models.
Stéphanie Da Silva, Å. Keita, S. Mohlin, S. Påhlman +4 more
2018Inflammatory Bowel Diseases33 citations
Semantic Scholar
TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival
P. L. Chavali, R. Saini, Q. Zhai, D. Vizlin-Hodzic +9 more
2014Cell Death and Disease33 citations Open access
Semantic Scholar
ARNT-dependent HIF-2 transcriptional activity is not sufficient to regulate downstream target genes in neuroblastoma.
C. Persson, Kristoffer von Stedingk, Elina Fredlund, D. Bexell +3 more
2020Experimental Cell Research32 citations Open access
Semantic Scholar
snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis.
Kristoffer von Stedingk, J. Koster, M. Piqueras, R. Noguera +7 more
2013Translational Oncology29 citations Open access
Semantic Scholar
Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma
K. Hansson, Katarzyna Radke, K. Aaltonen, J. Saarela +8 more
2020Science Translational Medicine27 citations Open access
Semantic Scholar
Myc-induced glutaminolysis bypasses HIF-driven glycolysis in hypoxic small cell lung carcinoma cells
M. Thorén, M. Vaapil, J. Staaf, M. Planck +3 more
2017OncoTarget27 citations Open access
Semantic Scholar
HIF-1alpha induces MXI1 by alternate promoter usage in human neuroblastoma cells.
Tobias Löfstedt, E. Fredlund, R. Noguera, S. Navarro +4 more
2009Experimental Cell Research27 citations
Semantic Scholar
Transcriptional adaptation of neuroblastoma cells to hypoxia.
E. Fredlund, Marie Ovenberger, K. Borg, S. Påhlman
2008Biochemical and Biophysical Research Communications - BBRC26 citations
Semantic Scholar
Erythropoietin Receptor Expression and Correlation to Tamoxifen Response and Prognosis in Breast Cancer
A. Larsson, K. Jirström, E. Fredlund, S. Nilsson +3 more
2009Clinical Cancer Research24 citations Open access
Semantic Scholar
Arsenic trioxide and neuroblastoma cytotoxicity
Helen M. Pettersson, J. Karlsson, Alexander Pietras, I. Øra +1 more
2007Journal of Bioenergetics and Biomembranes23 citations
Semantic Scholar
ALK positively regulates MYCN activity through repression of HBP1 expression
Shana Claeys, G. Denecker, K. Durinck, Bieke Decaesteker +24 more
2018Oncogene22 citations Open access
Semantic Scholar
Differential HIF-1α and HIF-2α Expression in Mammary Epithelial Cells during Fat Pad Invasion, Lactation, and Involution
S. Påhlman, L. R. Lund, A. Jögi
2015PLoS ONE22 citations Open access
Semantic Scholar
HIF-2α expression is suppressed in SCLC cells, which survive in moderate and severe hypoxia when HIF-1α is repressed.
Matilda Munksgaard Persson, M. Johansson, N. Monsef, M. Planck +5 more
2012American Journal of Pathology21 citations Open access
Semantic Scholar
EPO-independent functional EPO receptor in breast cancer enhances estrogen receptor activity and promotes cell proliferation.
Susann Reinbothe, A. Larsson, M. Vaapil, C. Wigerup +5 more
2014Biochemical and Biophysical Research Communications - BBRC20 citations Open access
Semantic Scholar

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