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R. Boulieu · SciRah

Researcher profile · Semantic Scholar

R. Boulieu

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R. Boulieu — researcher profile on SciRah

h-index: 23
Works: 99
Citations: 2,160

Most-cited papers

Contribution of CYP3A4, CYP2B6, and CYP2C9 isoforms to N-demethylation of ketamine in human liver microsomes.
Y. Hijazi, R. Boulieu
2002Drug Metabolism And Disposition299 citations
Semantic Scholar
Simultaneous determination of 6-thioguanine and methyl 6-mercaptopurine nucleotides of azathioprine in red blood cells by HPLC.
T. Dervieux, R. Boulieu
1998Clinical Chemistry232 citations Open access
Semantic Scholar
Advanced Characterization of Imiquimod-Induced Psoriasis-Like Mouse Model
Mehwish Jabeen, Anne-Sophie Boisgard, Alix Danoy, Naima El Kholti +5 more
2020Pharmaceutics161 citations Open access
Semantic Scholar
Liquid chromatography-tandem mass spectrometry analysis of erythrocyte thiopurine nucleotides and effect of thiopurine methyltransferase gene variants on these metabolites in patients receiving azathioprine/6-mercaptopurine therapy.
T. Dervieux, G. Meyer, R. Barham, M. Matsutani +4 more
2005Clinical Chemistry116 citations
Semantic Scholar
Pharmacokinetics and haemodynamics of ketamine in intensive care patients with brain or spinal cord injury.
Y. Hijazi, C. Bodonian, M. Bolon, F. Salord +1 more
2003British Journal of Anaesthesia109 citations Open access
Semantic Scholar
Propofol metabolites in man following propofol induction and maintenance.
P. Favetta, C. Degoute, J. P. Perdrix, C. Dufresne +2 more
2002British Journal of Anaesthesia109 citations Open access
Semantic Scholar
HPLC determination of ketamine, norketamine, and dehydronorketamine in plasma with a high-purity reversed-phase sorbent.
S. Bolze, R. Boulieu
1998Clinical Chemistry79 citations
Semantic Scholar
Development of an in vitro screening model for the biosynthesis of acyl glucuronide metabolites and the assessment of their reactivity toward human serum albumin.
S. Bolze, N. Bromet, Croisine Gay-Feutry, F. Massiere +2 more
2002Drug Metabolism And Disposition76 citations
Semantic Scholar
A rapid and simple HPLC method for the analysis of propofol in biological fluids.
Xavier Cussonneau, E. De Smet, Kristof Lantsoght, Jean-Paul Salvi +2 more
2007Journal of Pharmaceutical and Biomedical Analysis42 citations
Semantic Scholar
Determination of midazolam and its unconjugated 1-hydroxy metabolite in human plasma by high-performance liquid chromatography.
B. Lehmann, R. Boulieu
1995Journal of chromatography. B, Biomedical applications41 citations
Semantic Scholar
A Limited Sampling Strategy for Estimating Individual Pharmacokinetic Parameters of Coagulation Factor VIII in Patients With Hemophilia A
Magali Bolon-Larger, V. Chamouard, F. Bressolle, R. Boulieu
2007Therapeutic Drug Monitoring40 citations
Semantic Scholar
HPLC determination of mycophenolic acid and mycophenolic acid glucuronide in human plasma with hybrid material.
M. Bolon, L. Jeanpierre, Mirna El Barkil, K. Chelbi +2 more
2004Journal of Pharmaceutical and Biomedical Analysis36 citations
Semantic Scholar
High-performance liquid chromatographic determination of hypoxanthine and xanthine in biological fluids.
R. Boulieu, C. Bory, P. Baltassat, C. Gonnet
1982Journal of Chromatography A36 citations
Semantic Scholar
High-performance liquid chromatographic assay to detect hydroxylate and conjugate metabolites of propofol in human urine.
P. Favetta, J. Guitton, C. Degoute, L. V. van Daele +1 more
2000Journal of Chromatography B: Biomedical Sciences and Applications33 citations
Semantic Scholar
Monitoring of Azathioprine Metabolites in Pediatric Patients With Autoimmune Hepatitis
T. Nguyen, Marina Daubard, C. le Gall, M. Larger +2 more
2010Therapeutic Drug Monitoring32 citations
Semantic Scholar
Protein binding of ketamine and its active metabolites to human serum
Y. Hijazi, R. Boulieu
2002European Journal of Clinical Pharmacology31 citations
Semantic Scholar
Comparison of capillary electrophoretic and liquid chromatographic determination of hypoxanthine and xanthine for the diagnosis of xanthinuria.
C. Bory, C. Chantin, R. Boulieu
1996Journal of Chromatography A30 citations
Semantic Scholar
Dynamics of MLAEP changes in midazolam-induced sedation.
D. Morlet, Olivier F. Bertrand, F. Salord, R. Boulieu +2 more
1997Electroencephalography and Clinical Neurophysiology26 citations
Semantic Scholar
Effects of mutations on herpes simplex virus 1 thymidine kinase functionality: an in vitro assay based on detection of monophosphate forms of acyclovir and thymidine using HPLC/DAD.
Nicolas Malartre, R. Boulieu, Nisrine Falah, J. Cortay +3 more
2012Antiviral Research25 citations
Semantic Scholar
Pharmacokinetics of midazolam and its main metabolite 1-hydroxymidazolam in intensive care patients
R. Boulieu, B. Lehmann, F. Salord, C. Fisher +1 more
1998European journal of drug metabolism and pharmacokinetics25 citations
Semantic Scholar
High-performance liquid chromatographic method for the analysis of purine and pyrimidine bases, ribonucleosides and deoxyribonucleosides in biological fluids.
R. Boulieu, C. Bory, C. Gonnet
1985Journal of Chromatography A25 citations
Semantic Scholar
Exploring Associations of 6-Thioguanine Nucleotide Levels and Other Predictive Factors with Therapeutic Response to Azathioprine in Pediatric Patients with IBD Using Multilevel Analysis
Thi-Van-Anh Nguyen, D. Vu, T. Nguyen, A. Lachaux +1 more
2013Inflammatory Bowel Diseases23 citations Open access
Semantic Scholar
CONTRIBUTION OF CYP 3 A 4 , CYP 2 B 6 , AND CYP 2 C 9 ISOFORMS TO N-DEMETHYLATION OF KETAMINE IN HUMAN LIVER MICROSOMES
Y. Hijazi, R. Boulieu
200223 citations
Semantic Scholar
Solid-Phase Microextraction of Human Plasma Samples for Determination of Sufentanil by Gas Chromatography–Mass Spectrometry
Chantal Paradis, C. Dufresne, M. Bolon, R. Boulieu
2002Therapeutic Drug Monitoring22 citations
Semantic Scholar
Comparison of Red Cell Transfusion and Polyethylene Glycol-Modified Adenosine Deaminase Therapy in an Adenosine Deaminase-Deficient Child: Measurement of Erythrocyte Deoxyadenosine Triphosphate as a Useful Tool
C. Bory, R. Boulieu, G. Souillet, C. Chantin +3 more
1990Pediatric Research22 citations
Semantic Scholar
Detection of new propofol metabolites in human urine using gas chromatography/mass spectrometry and liquid chromatography/mass spectrometry techniques.
P. Favetta, C. Dufresne, M. Désage, O. Païssé +3 more
2000Rapid Communications in Mass Spectrometry21 citations
Semantic Scholar
Homogentisic acid determined in biological fluids by HPLC.
C. Bory, R. Boulieu, C. Chantin, M. Mathieu
1989Clinical Chemistry21 citations
Semantic Scholar
Relationship Between Azathioprine Dosage and Thiopurine Metabolites in Pediatric IBD Patients: Identification of Covariables Using Multilevel Analysis
Thi-Van-Anh Nguyen, D. Vu, T. Nguyen, A. Lachaux +1 more
2013Therapeutic Drug Monitoring20 citations
Semantic Scholar
High-performance liquid chromatographic determination of ganciclovir in plasma.
R. Boulieu, N. Bleyzac, S. Ferry
1991Journal of Chromatography A18 citations
Semantic Scholar
Simultaneous determination of allopurinol, oxipurinol, hypoxanthine and xanthine in biological fluids by high-performance liquid chromatography.
R. Boulieu, C. Bory, P. Baltassat, C. Gonnet
1984Journal of Chromatography A18 citations
Semantic Scholar
lntracellular thiopurine nucleotides and azathioprine myelotoxicity in organ transplant patients
R. Boulieu, A. Lenoir, M. Bertocchi, J. Mornex
199717 citations
Semantic Scholar
Liquid-chromatographic study of purine metabolism abnormalities in purine nucleoside phosphorylase deficiency.
C. Chantin, B. Bonin, R. Boulieu, C. Bory
1996Clinical Chemistry16 citations
Semantic Scholar
Solid-phase extraction of diltiazem and its metabolites from plasma prior to high-performance liquid chromatography.
R. Boulieu, J. Bonnefous, S. Ferry
1990Journal of Chromatography A15 citations
Semantic Scholar
Liquid-chromatographic measurement of purine nucleotides in blood cells.
R. Boulieu, C. Bory, C. Gonnet
1985Clinical Chemistry15 citations
Semantic Scholar
Ex-Vivo percutaneous absorption of enrofloxacin: Comparison of LMOG organogel vs. pentravan cream.
P. Kirilov, Van Hung Tran, Alban Ducrotté-Tassel, Jean-Paul Salvi +4 more
2016International journal of pharmaceutics14 citations
Semantic Scholar
Relationship between MPA free fraction and free MPAG concentrations in heart transplant recipients based on simultaneous HPLC quantification of the target compounds in human plasma.
Xavier Cussonneau, Magali Bolon-Larger, C. Prunet-Spano, O. Bastien +1 more
2007Journal of chromatography. B, Analytical technologies in the biomedical and life sciences14 citations
Semantic Scholar
[Cooperation between general practitioners and pharmacists: a systematic review].
P. Michot, O. Catala, Irène Supper, R. Boulieu +3 more
2013La Sante publique13 citations
Semantic Scholar
Usefulness of Thiopurine Metabolites in Predicting Azathioprine Resistance in Pediatric IBD Patients
Thi-Van-Anh Nguyen, T. Nguyen, A. Lachaux, R. Boulieu
2013Journal of clinical pharmacology12 citations
Semantic Scholar
ITPA Activity in Children Treated by Azathioprine: Relationship to the Occurrence of Adverse Drug Reactions and Inflammatory Response
A. Citterio-Quentin, M. Moulsma, M. Gustin, A. Lachaux +1 more
2018Basic & Clinical Pharmacology & Toxicology11 citations
Semantic Scholar
Age-Related Variability of Mycophenolate Mofetil Exposure in Stable Pediatric Liver Transplant Recipients and Influences of Donor Characteristics
F. Parant, C. Rivet, R. Boulieu, M. Gagnieu +3 more
2009Therapeutic Drug Monitoring11 citations
Semantic Scholar
Intracellular thiopurine nucleotides and azathioprine myelotoxicity in organ transplant patients.
R. Boulieu, A. Lenoir, M. Bertocchi, J. Mornex
1997British Journal of Clinical Pharmacology11 citations
Semantic Scholar
Stability of ganciclovir in blood samples.
R. Boulieu, N. Bleyzac
1994Journal of Pharmaceutical and Biomedical Analysis11 citations
Semantic Scholar
ITPA Activity in Adults and Children Treated With or Without Azathioprine: Relationship Between TPMT Activity, Thiopurine Metabolites, and Co-medications
A. Citterio-Quentin, M. Moulsma, M. Gustin, R. Boulieu
2017Therapeutic Drug Monitoring10 citations
Semantic Scholar
Predictions of Carbamazepine Concentrations Using a Bayesian Program (PKS System, Abbott): A Retrospective Evaluation in an Outpatient Population
J. Gaulier, R. Boulieu, C. Fischer, F. Mauguière
1997The Journal of pharmacy and pharmacology10 citations
Semantic Scholar
Neurologic side-effects of ganciclovir.
F. Combarnous, D. Fouque, P. Chossegros, R. Boulieu +2 more
1994Clinical Nephrology10 citations
Semantic Scholar
Stability of diltiazem and its metabolites in human blood samples.
J. Bonnefous, R. Boulieu, C. Lahet
1992Journal of Pharmacy and Science10 citations
Semantic Scholar
Determination of Diltiazem and its Metabolites in Plasma by High Performance Liquid Chromatography
R. Boulieu, J. Bonnefous, S. Ferry
199010 citations
Semantic Scholar
Determination of Inosine Triphosphate Pyrophosphatase Phenotype in Human Red Blood Cells Using HPLC
A. Citterio-Quentin, Jean-Paul Salvi, R. Boulieu
2012Therapeutic Drug Monitoring9 citations
Semantic Scholar
Stability of Sufentanil in Human Plasma Samples
C. Dufresne, P. Favetta, Chantal Paradis, R. Boulieu
2001Therapeutic Drug Monitoring9 citations
Semantic Scholar
Comparison of Solid-Phase Extraction and Liquid-Liquid Extraction Methods for Liquid Chromatographic Determination of Diltiazem and its Metabolites in Plasma
J. Bonnefous, R. Boulieu
19909 citations
Semantic Scholar

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