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N. Bleyzac · SciRah

Researcher profile · Semantic Scholar

N. Bleyzac

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N. Bleyzac — researcher profile on SciRah

h-index: 24
Works: 116
Citations: 2,003

Most-cited papers

Outcome of 27 patients with Hurler's syndrome transplanted from either related or unrelated haematopoietic stem cell sources
G. Souillet, N. Guffon, I. Maire, M. Pujol +14 more
2003Bone Marrow Transplantation218 citations Open access
Semantic Scholar
Improved clinical outcome of paediatric bone marrow recipients using a test dose and Bayesian pharmacokinetic individualization of busulfan dosage regimens
N. Bleyzac, G. Souillet, Paul Magron, A. Janoly +7 more
2001Bone Marrow Transplantation137 citations Open access
Semantic Scholar
Azithromycin for COVID-19: More Than Just an Antimicrobial?
N. Bleyzac, S. Goutelle, L. Bourguignon, M. Tod
2020Clinical drug investigation113 citations Open access
Semantic Scholar
Pharmacokinetic Behavior and Appraisal of Intravenous Busulfan Dosing in Infants and Older Children: The Results of a Population Pharmacokinetic Study From a Large Pediatric Cohort Undergoing Hematopoietic Stem-Cell Transplantation
A. Paci, G. Vassal, D. Moshous, J. Dalle +8 more
2012Therapeutic Drug Monitoring84 citations
Semantic Scholar
Accurately achieving target busulfan exposure in children and adolescents with very limited sampling and the BestDose software
M. Neely, M. Philippe, Teresa Rushing, Xiaowei Fu +5 more
2016Therapeutic Drug Monitoring65 citations Open access
Semantic Scholar
Relationship between CsA trough blood concentration and severity of acute graft-versus-host disease after paediatric stem cell transplantation from matched-sibling or unrelated donors
P. Martin, N. Bleyzac, G. Souillet, C. Galambrun +4 more
2003Bone Marrow Transplantation52 citations Open access
Semantic Scholar
Clinical and pharmacological risk factors for acute graft-versus-host disease after paediatric bone marrow transplantation from matched-sibling or unrelated donors
P. Martin, N. Bleyzac, G. Souillet, C. Galambrun +4 more
2003Bone Marrow Transplantation51 citations
Semantic Scholar
Influence of Underlying Disease on Busulfan Disposition in Pediatric Bone Marrow Transplant Recipients: A Nonparametric Population Pharmacokinetic Study
V. Bertholle-Bonnet, N. Bleyzac, C. Galambrun, V. Mialou +3 more
2007Therapeutic Drug Monitoring46 citations
Semantic Scholar
In Vivo Quantitative Prediction of the Effect of Gene Polymorphisms and Drug Interactions on Drug Exposure for CYP2C19 Substrates
S. Goutelle, L. Bourguignon, N. Bleyzac, Joanna L. Berry +2 more
2013AAPS Journal42 citations Open access
Semantic Scholar
Cyclosporin A inhibits dendritic cell maturation promoted by TNF‐α or LPS but not by double‐stranded RNA or CD40L
Karine Duperrier, A. Farre, J. Bienvenu, N. Bleyzac +4 more
2002Journal of Leukocyte Biology41 citations
Semantic Scholar
New sensitive assay of vancomycin in human plasma using high-performance liquid chromatography and electrochemical detection.
P. Favetta, J. Guitton, N. Bleyzac, C. Dufresne +1 more
2001Journal of Chromatography B: Biomedical Sciences and Applications40 citations
Semantic Scholar
Maximal concentration of intravenous busulfan as a determinant of veno-occlusive disease: a pharmacokinetic-pharmacodynamic analysis in 293 hematopoietic stem cell transplanted children
M. Philippe, M. Neely, Teresa Rushing, Y. Bertrand +2 more
2018Bone Marrow Transplantation39 citations
Semantic Scholar
Short communication HSV excretion after bone marrow transplantation: a 4-year survey
F. Morfin, K. Bilger, A. Boucher, A. Thiébaut +7 more
200438 citations
Semantic Scholar
Proton Pump Inhibitors are Risk Factors for Viral Infections: Even for COVID-19?
B. Charpiat, N. Bleyzac, M. Tod
2020Clinical drug investigation35 citations Open access
Semantic Scholar
Medication adherence in pediatric transplantation and assessment methods: a systematic review
D. Hoegy, N. Bleyzac, P. Robinson, Y. Bertrand +2 more
2019Patient Preference and Adherence35 citations Open access
Semantic Scholar
Intra-individual Pharmacokinetic Variability of Intravenous Busulfan in Hematopoietic Stem Cell-Transplanted Children
Hanen Marsit, M. Philippe, M. Neely, Teresa Rushing +6 more
2020Clinical Pharmacokinetics34 citations
Semantic Scholar
Rapid and sensitive high-performance liquid chromatographic method for busulfan assay in plasma.
N. Bleyzac, P. Barou, G. Aulagner
2000Journal of Chromatography B: Biomedical Sciences and Applications33 citations
Semantic Scholar
High-dose ganciclovir in HHV-6 encephalitis of an immunocompetent child.
Tuire Olli-Lähdesmäki, L. Haataja, R. Parkkola, M. Waris +2 more
2010Pediatric Neurology30 citations
Semantic Scholar
Increased Risk of Thrombosis Associated with Peripherally Inserted Central Catheters Compared with Conventional Central Venous Catheters in Children with Leukemia
Pierre‐Amaël Noailly Charny, N. Bleyzac, R. Ohannessian, Edouard Aubert +2 more
2018Jornal de Pediatria28 citations
Semantic Scholar
A Pharmacodynamic Model of Ganciclovir Antiviral Effect and Toxicity for Lymphoblastoid Cells Suggests a New Dosing Regimen To Treat Cytomegalovirus Infection
A. Janoly-Dumenil, I. Rouvet, N. Bleyzac, F. Morfin +2 more
2012Antimicrobial Agents and Chemotherapy28 citations Open access
Semantic Scholar
Erythromycin Promotes Gastric Emptying During Acute Pain in Volunteers
L. Bouvet, F. Duflo, N. Bleyzac, F. Mion +3 more
2006Anesthesia and Analgesia26 citations Open access
Semantic Scholar
Should busulfan therapeutic range be narrowed in pediatrics? Experience from a large cohort of hematopoietic stem cell transplant children
M. Philippe, S. Goutelle, J. Guitton, X. Fonrose +4 more
2016Bone Marrow Transplantation25 citations
Semantic Scholar
Pharmacokinetic Drug-Drug Interaction of Calcium Channel Blockers With Cyclosporine in Hematopoietic Stem Cell Transplant Children
E. Bernard, S. Goutelle, Y. Bertrand, N. Bleyzac
2014The Annals of Pharmacotherapy24 citations
Semantic Scholar
Effects of Subhypnotic Doses of Propofol on Gastric Emptying in Volunteers
D. Chassard, S. Lansiaux, F. Duflo, F. Mion +3 more
2002Anesthesiology23 citations
Semantic Scholar
Population pharmacokinetics of amikacin at birth and interindividual variability in renal maturation
N. Bleyzac, V. Varnier, J. Labaune, S. Corvaisier +4 more
2001European Journal of Clinical Pharmacology23 citations
Semantic Scholar
Model-Based Comparative Analysis of Rifampicin and Rifabutin Drug-Drug Interaction Profile
V. Tuloup, Mathilde France, R. Garreau, N. Bleyzac +3 more
2021Antimicrobial Agents and Chemotherapy21 citations Open access
Semantic Scholar
Medication adherence after pediatric allogeneic stem cell transplantation: Barriers and facilitators.
D. Hoegy, N. Bleyzac, C. Rochet, H. de Fréminville +5 more
2019European Journal of Oncology Nursing21 citations
Semantic Scholar
Simple and rapid high-performance liquid chromatographic method for nelfinavir, M8 nelfinavir metabolite, ritonavir and saquinavir assay in plasma.
A. Janoly, N. Bleyzac, P. Favetta, M. C. Gagneu +4 more
2002Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20 citations
Semantic Scholar
Cytomegalovirus and adenovirus infections and diseases among 75 paediatric unrelated allogeneic bone marrow transplant recipients
F. Morfin, A. Boucher, F. Najioullah, Y. Bertrand +9 more
2004Journal of Medical Virology19 citations
Semantic Scholar
Two cases of varicella zoster virus meningitis found in pediatric patients after bone marrow transplantation despite valaciclovir prophylaxis and without skin lesions
N. Lévêque, C. Galambrun, F. Najioullah, N. Bleyzac +2 more
2006Journal of Medical Virology17 citations
Semantic Scholar
Impact of a change in protected environment on the occurrence of severe bacterial and fungal infections in children undergoing hematopoietic stem cell transplantation
Clara Libbrecht, Marie-Pierre Goutagny, J. Bacchetta, C. Ploton +5 more
2016European Journal of Haematology16 citations
Semantic Scholar
Effect of Duration and Intensity of Ganciclovir Exposure on Lymphoblastoid Cell Toxicity
A. Janoly-Dumenil, I. Rouvet, N. Bleyzac, Y. Bertrand +2 more
2009Antiviral Chemistry & Chemotherapy16 citations
Semantic Scholar
Improvement in the Outcome of Invasive Aspergillosis in a Pediatric Hematology Department: A 10-Year Review
C. Domenech, C. Leick-Courtois, A. Bienvenu, J. Pracros +3 more
2015Journal of pediatric hematology/oncology15 citations
Semantic Scholar
Influence of Dosing Schedule on Organ Exposure to Cyclosporin in Pediatric Hematopoietic Stem Cell Transplantation: Analysis with a PBPK Model
Cécile Gérard, N. Bleyzac, P. Girard, G. Freyer +2 more
2010Pharmaceutical Research15 citations
Semantic Scholar
Methylprednisolone-related liver injury: A descriptive study using the French pharmacovigilance database.
J. Cottin, S. Pierre, V. Pizzoglio, C. Simon +4 more
2020Clinics And Research in Hepatology and Gastroenterology14 citations Open access
Semantic Scholar
Continuous intravenous vancomycin in children with normal renal function hospitalized in hematology–oncology: prospective validation of a dosing regimen optimizing steady‐state concentration
D. Hoegy, S. Goutelle, N. Garnier, C. Rénard +4 more
2018Fundamental & Clinical Pharmacology14 citations
Semantic Scholar
Bayesian Networks: A New Approach to Predict Therapeutic Range Achievement of Initial Cyclosporine Blood Concentration After Pediatric Hematopoietic Stem Cell Transplantation
V. Leclerc, M. Ducher, N. Bleyzac
2018Drugs in R&D14 citations Open access
Semantic Scholar
Cytomegalovirus Infection in Pediatric Allogenic Hematopoietic Stem Cell Transplantation. A Single Center Experience
Mohamed Sedky, Y. Mekki, V. Mialou, N. Bleyzac +4 more
2014Pediatric Hematology & Oncology14 citations
Semantic Scholar
Cryptosporidiosis in children with acute lymphoblastic leukemia on maintenance chemotherapy.
C. Domenech, M. Rabodonirina, N. Bleyzac, M. Pagès +1 more
2011Journal of pediatric hematology/oncology14 citations
Semantic Scholar
Links Between Cyclosporin Exposure in Tissues and Graft-Versus-Host Disease in Pediatric Bone Marrow Transplantation: Analysis by a PBPK Model
Cécile Gérard, N. Bleyzac, P. Girard, G. Freyer +2 more
2010Pharmaceutical Research14 citations
Semantic Scholar
Comparison of nonlinear mixed-effect and non-parametric expectation maximisation modelling for Bayesian estimation of carboplatin clearance in children
A. Patoux, N. Bleyzac, A. Boddy, F. Doz +5 more
2001European Journal of Clinical Pharmacology14 citations Open access
Semantic Scholar
Sickle cell disease perceptions of caregivers, adolescent, and adult patients: Barriers and facilitators to medical care adherence.
D. Hoegy, R. Guilloux, N. Bleyzac, Alexandra Gauthier-Vasserot +5 more
2020Journal of Advanced Nursing13 citations
Semantic Scholar
A Nonparametric Method to Optimize Initial Drug Dosing and Attainment of a Target Exposure Interval: Concepts and Application to Busulfan in Pediatrics
M. Philippe, M. Neely, Y. Bertrand, N. Bleyzac +1 more
2017Clinical Pharmacokinetics13 citations
Semantic Scholar
High methotrexate exposure and toxicity in children with t(9;22) positive acute lymphoblastic leukaemia treated with imatinib
Constance Loue, N. Garnier, Y. Bertrand, N. Bleyzac
2015Journal of Clinical Pharmacy and Therapeutics13 citations Open access
Semantic Scholar
A Generic Model for Quantitative Prediction of Interactions Mediated by Efflux Transporters and Cytochromes: Application to P-Glycoprotein and Cytochrome 3A4
M. Tod, S. Goutelle, N. Bleyzac, L. Bourguignon
2018Clinical Pharmacokinetics12 citations
Semantic Scholar
Pharmacokinetic Drug Interaction Between Cyclosporine and Imatinib in Bone Marrow Transplant Children and Model-Based Reappraisal of Imatinib Drug Interaction Profile
N. Bleyzac, K. Kébaili, V. Mialou, Y. Bertrand +1 more
2014Therapeutic Drug Monitoring12 citations
Semantic Scholar
Oral voriconazole dose in children: one size does not fit all.
S. Goutelle, R. Larcher, C. Padoin, V. Mialou +1 more
2010Clinical Infectious Diseases12 citations Open access
Semantic Scholar
Identification of Cytochrome P450-Mediated Drug–Drug Interactions at Risk in Cases of Gene Polymorphisms by Using a Quantitative Prediction Model
Nicolas Fermier, L. Bourguignon, S. Goutelle, N. Bleyzac +1 more
2018Clinical Pharmacokinetics11 citations
Semantic Scholar
[A French survey on the resort of oral alternative complementary medicines used in children with cancer].
C. Philibert, D. Hoegy, M. Philippe, P. Marec-Berard +1 more
2015Bulletin du Cancer11 citations
Semantic Scholar
Human herpes virus-6 encephalitis in a paediatric bone marrow recipient: successful treatment with pharmacokinetic monitoring and high doses of ganciclovir
A. Janoly-Dumenil, C. Galambrun, T. Basset, V. Mialou +2 more
2006Bone Marrow Transplantation11 citations
Semantic Scholar

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