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M. Schwickart · SciRah

Researcher profile · Semantic Scholar

M. Schwickart

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M. Schwickart — researcher profile on SciRah

h-index: 14
Works: 34
Citations: 1,995

Most-cited papers

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
M. Schwickart, Xiaodong Huang, J. Lill, Jin-Feng Liu +10 more
2010Nature648 citations
Semantic Scholar
Proteasome subunit Rpn1 binds ubiquitin-like protein domains
Suzanne Elsasser, R. R. Gali, M. Schwickart, C. N. Larsen +6 more
2002Nature Cell Biology492 citations
Semantic Scholar
Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1.
M. Petronczki, Joao Matos, Saori Mori, J. Gregan +6 more
2006Cell208 citations Open access
Semantic Scholar
The yeast APC/C subunit Mnd2 prevents premature sister chromatid separation triggered by the meiosis-specific APC/C-Ama1.
Tobias Oelschlaegel, M. Schwickart, Joao Matos, Aliona Bogdanova +4 more
2005Cell112 citations Open access
Semantic Scholar
Swm1/Apc13 Is an Evolutionarily Conserved Subunit of the Anaphase-Promoting Complex Stabilizing the Association of Cdc16 and Cdc27
M. Schwickart, Jan Havliš, B. Habermann, Aliona Bogdanova +4 more
2004Molecular and Cellular Biology72 citations Open access
Semantic Scholar
Receptor occupancy assessment by flow cytometry as a pharmacodynamic biomarker in biopharmaceutical development
M. Liang, M. Schwickart, A. Schneider, I. Vainshtein +3 more
2015Cytometry. Part B, Clinical cytometry61 citations Open access
Semantic Scholar
Cabozantinib in combination with atezolizumab in patients with metastatic castration-resistant prostate cancer: results from an expansion cohort of a multicentre, open-label, phase 1b trial (COSMIC-021).
N. Agarwal, B. McGregor, B. Maughan, T. Dorff +15 more
2022The Lancet Oncology58 citations
Semantic Scholar
A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis
Nicholas A Dompe, Celina Sanchez Rivers, Li Li, Shaun Cordes +7 more
2011Proceedings of the National Academy of Sciences of the United States of America56 citations Open access
Semantic Scholar
PK-PD modeling of protein drugs: implications in assay development.
L. Roskos, A. Schneider, I. Vainshtein, M. Schwickart +4 more
2011Bioanalysis49 citations
Semantic Scholar
Pharmacokinetics, Pharmacodynamics, and Safety of MEDI4212, an Anti-IgE Monoclonal Antibody, in Subjects with Atopy: A Phase I Study
E. Sheldon, M. Schwickart, Jing Li, Keunpyo Kim +4 more
2016Advances in Therapy41 citations
Semantic Scholar
MEDI1873, a potent, stabilized hexameric agonist of human GITR with regulatory T-cell targeting potential
N. Tigue, Lisa Bamber, J. Andrews, S. Ireland +23 more
2017Oncoimmunology33 citations Open access
Semantic Scholar
Duration of Response to Luspatercept in Patients (Pts) Requiring Red Blood Cell (RBC) Transfusions with Myelofibrosis (MF) - Updated Data from the Phase 2 ACE-536-MF-001 Study
A. Gerds, A. Vannucchi, F. Passamonti, M. Kremyanskaya +18 more
202031 citations Open access
Semantic Scholar
Interference in immunoassays to support therapeutic antibody development in preclinical and clinical studies.
M. Schwickart, I. Vainshtein, Rozanne Lee, A. Schneider +1 more
2014Bioanalysis29 citations
Semantic Scholar
Combination of azacitidine and enasidenib enhances leukemic cell differentiation and cooperatively hypomethylates DNA.
Kyle J. Macbeth, V. Chopra, Lin Tang, B. Zheng +6 more
2021Experimental Hematology14 citations Open access
Semantic Scholar
Swm 1 / Apc 13 Is an Evolutionarily Conserved Subunit of the Anaphase-Promoting Complex Stabilizing the Association of Cdc 16 and Cdc 27
M. Schwickart, Jan Havliš, B. Habermann, Aliona Bogdanova +4 more
200413 citations
Semantic Scholar
Pharmacokinetics and pharmacodynamics of MEDI4736, a fully human anti-programmed death ligand 1 (PD-L1) monoclonal antibody, in patients with advanced solid tumors.
Xuyang Song, Min Pak, Carlos Chávez, M. Liang +8 more
201510 citations
Semantic Scholar
Identification and elimination of target-related matrix interference in a neutralizing anti-drug antibody assay.
M. Schwickart, Freshta Mehrzai, J. Pearson, Nabila Shaghasi +5 more
2014JIM - Journal of Immunological Methods10 citations Open access
Semantic Scholar
Next Generation Ligand Binding Assays—Review of Emerging Real-Time Measurement Technologies
Stephanie Fraser, M. Cameron, Edward O’Connor, M. Schwickart +2 more
2014AAPS Journal9 citations Open access
Semantic Scholar
Current Trends in Ligand Binding Real-Time Measurement Technologies
Stephanie Fraser, Judy Y Shih, Mark Ware, Edward O’Connor +4 more
2017AAPS Journal8 citations
Semantic Scholar
Multiplexing of receptor occupancy measurements for pharmacodynamic biomarker assessment of biopharmaceuticals
I. Vainshtein, A. Schneider, Bo Sun, M. Schwickart +2 more
2015Cytometry. Part B, Clinical cytometry8 citations Open access
Semantic Scholar
Evaluation of assay interference and interpretation of CXCR4 receptor occupancy results in a preclinical study with MEDI3185, a fully human antibody to CXCR4
M. Schwickart, Carlos Chávez, Simon J. Henderson, I. Vainshtein +6 more
2015Cytometry. Part B, Clinical cytometry8 citations Open access
Semantic Scholar
481P A phase I first-in-human study of XL092 in patients (pts) with locally advanced or metastatic solid tumors: Results from dose-escalation of XL092 alone and in combination with atezolizumab
M. R. Sharma, V. Subbiah, G. Shapiro, S. Pål +8 more
2022Annals of Oncology7 citations Open access
Semantic Scholar
Rapamycin (Sirolimus) and Rap-536 Increase Red Blood Cell Parameters through Distinct Mechanisms in Wild-Type and Thalassemic Mice
M. Acar, Madhulika Jupelli, Kyle J. Macbeth, M. Schwickart
20206 citations
Semantic Scholar
Luspatercept Significantly Reduces Red Blood Cell (RBC) Transfusion Burden, Regardless of Gene Mutation Frequency, Spectrum, and Prognostic Significance, Among Patients (Pts) with LR-MDS Enrolled in the MEDALIST Trial
U. Platzbecker, D. Dunshee, R. Komrokji, G. Mufti +19 more
2019Blood5 citations Open access
Semantic Scholar
Effect of Luspatercept on Biomarkers of Erythropoiesis in Patients (Pts) with Lower-Risk Myelodysplastic Syndromes (LR-MDS) in the Medalist Trial
U. Platzbecker, Yi-Ming Zhu, X. Ha, A. Risueño +11 more
20203 citations Open access
Semantic Scholar
Pharmacokinetics and pharmacodynamics of MEDI4736, a fully human anti-programmed death ligand 1 (PD-L1) monoclonal antibody, in combination with tremelimumab in patients with advanced non-small cell lung cancer (NSCLC).
Manasa Tatipalli, Xuyang Song, Min Pak, Carlos Chávez +9 more
20153 citations
Semantic Scholar
STELLAR-303: A phase 3 study of XL092 in combination with atezolizumab versus regorafenib in patients with previously treated metastatic colorectal cancer.
J. Hecht, J. Tabernero, A. Parikh, Yi-Jia Wang +4 more
2023Journal of Clinical Oncology2 citations
Semantic Scholar
P-35 Zanzalintinib (XL092) in combination with atezolizumab for previously treated metastatic colorectal cancer
J. Tabernero, A. Saeed, A. Parikh, Y. Wang +4 more
2023Annals of Oncology1 citations Open access
Semantic Scholar
Luspatercept Redistributes Body Iron to the Liver in Transfusion-Dependent-Thalassemia (TDT) during Erythropoietic Response
M. Garbowski, M. Ugidos, A. Risueño, R. Suragani +5 more
2021Blood1 citations Open access
Semantic Scholar
Current Trends in Ligand Binding Real-Time Measurement Technologies
Stephanie Fraser, Judy Y Shih, Mark Ware, Edward O’Connor +4 more
2017AAPS Journal1 citations
Semantic Scholar
Rap-536 Induces Reticulocyte Maturation in Wild-Type Mice, Increases Survival of Beta-Thalassemic Reticulocytes, and Increases Red Blood Cells in a Mouse Model of Alpha-Thalassemia
M. Acar, Madhulika Jupelli, R. Abbiati, Harish N. Ramanathan +8 more
20200 citations
Semantic Scholar
Immunoassays
M. Schwickart, I. Vainshtein
2019Nijkamp and Parnham's Principles of Immunopharmacology0 citations
Semantic Scholar
GDF15 and Erythroferrone Mark Erythropoietic Response to ACE-011 (Sotatercept) in Thalassemia
M. Garbowski, O. Hermine, M. Cappellini, R. Origa +17 more
2018Blood0 citations Open access
Semantic Scholar
Next Generation Ligand Binding Assays—Review of Emerging Real-Time Measurement Technologies
Stephanie Fraser, M. Cameron, Edward O’Connor, M. Schwickart +2 more
2014AAPS Journal0 citations Open access
Semantic Scholar

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I. Vainshtein×6
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