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T. Sengoku · SciRah

Researcher profile · Semantic Scholar

T. Sengoku

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T. Sengoku — researcher profile on SciRah

h-index: 21
Works: 69
Citations: 2,140

Most-cited papers

Structural basis for RNA unwinding by the DEAD-box protein Drosophila Vasa.
T. Sengoku, O. Nureki, A. Nakamura, Satoru Kobayashi +1 more
2006Cell558 citations Open access
Semantic Scholar
UTX and UTY Demonstrate Histone Demethylase-Independent Function in Mouse Embryonic Development
Karl B. Shpargel, T. Sengoku, S. Yokoyama, T. Magnuson
2012PLoS Genetics294 citations Open access
Semantic Scholar
SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53
Zhanyun Tang, Wei-Yi Chen, Miho Shimada, U. Nguyen +7 more
2013Cell159 citations Open access
Semantic Scholar
Structural basis for histone H3 Lys 27 demethylation by UTX/KDM6A.
T. Sengoku, S. Yokoyama
2011Genes & Development141 citations Open access
Semantic Scholar
Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A.
S. Mimasu, T. Sengoku, S. Fukuzawa, T. Umehara +1 more
2008Biochemical and Biophysical Research Communications - BBRC125 citations
Semantic Scholar
Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic β-amino acids
T. Katoh, T. Sengoku, K. Hirata, K. Ogata +1 more
2020Nature Chemistry103 citations
Semantic Scholar
A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase
Yoshiaki Kise, Sang Won Lee, S. G. Park, S. Fukai +5 more
2004Nature Structural &Molecular Biology71 citations
Semantic Scholar
Structural basis of transcription regulation by CNC family transcription factor, Nrf2
T. Sengoku, M. Shiina, Kae Suzuki, K. Hamada +15 more
2022Nucleic Acids Research52 citations Open access
Semantic Scholar
De Novo Discovery of Thiopeptide Pseudo-natural Products Acting as Potent and Selective TNIK Kinase Inhibitors
A. A. Vinogradov, Yue Zhang, K. Hamada, Jun-Shi Chang +8 more
2022Journal of the American Chemical Society51 citations Open access
Semantic Scholar
Crystal Structure of tRNA Adenosine Deaminase (TadA) from Aquifex aeolicus*
M. Kuratani, R. Ishii, Y. Bessho, R. Fukunaga +4 more
2005Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Genetic landscape of Rett syndrome-like phenotypes revealed by whole exome sequencing
Kazuhiro Iwama, T. Mizuguchi, E. Takeshita, E. Nakagawa +44 more
2019Journal of Medical Genetics39 citations
Semantic Scholar
Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2
Ko Sato, Amarjeet Kumar, K. Hamada, Chikako Okada +8 more
2021Nature Communications38 citations Open access
Semantic Scholar
Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase
H. Sasaki, S. Sekine, T. Sengoku, R. Fukunaga +6 more
2006Proceedings of the National Academy of Sciences of the United States of America37 citations Open access
Semantic Scholar
Systematic analysis of exonic germline and postzygotic de novo mutations in bipolar disorder
Masaki Nishioka, A. Kazuno, Takumi Nakamura, Naomi Sakai +19 more
2021Nature Communications36 citations Open access
Semantic Scholar
An Ultrapotent and Selective Cyclic Peptide Inhibitor of Human β-Factor XIIa in a Cyclotide Scaffold.
Wenyu Liu, S. D. de Veer, Yen-Hua Huang, T. Sengoku +8 more
2021Journal of the American Chemical Society32 citations
Semantic Scholar
Brain monoamine vesicular transport disease caused by homozygous SLC18A2 variants: A study in 42 affected individuals.
Ken Saida, R. Maroofian, T. Sengoku, T. Mitani +83 more
2022Genetics in Medicine31 citations Open access
Semantic Scholar
LimF is a versatile prenyltransferase for histidine-C-geranylation on diverse non-natural substrates
Yuchen Zhang, K. Hamada, D. T. Nguyen, Sumika Inoue +8 more
2022Nature Catalysis30 citations Open access
Semantic Scholar
Substrate tRNA Recognition Mechanism of a Multisite-specific tRNA Methyltransferase, Aquifex aeolicus Trm1, Based on the X-ray Crystal Structure*
T. Awai, Anna Ochi, Ihsanawati, T. Sengoku +4 more
2011Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Phenotype-genotype correlations in patients with GNB1 gene variants, including the first three reported Japanese patients to exhibit spastic diplegia, dyskinetic quadriplegia, and infantile spasms.
W. Endo, S. Ikemoto, N. Togashi, Takuya Miyabayashi +16 more
2019Brain & development (Tokyo. 1979)26 citations
Semantic Scholar
Structural basis of protein arginine rhamnosylation by glycosyltransferase EarP
T. Sengoku, Takehiro Suzuki, N. Dohmae, Chiduru Watanabe +6 more
2018Nature Chemical Biology24 citations
Semantic Scholar
Pathogenic variants in the survival of motor neurons complex gene GEMIN5 cause cerebellar atrophy
Ken Saida, J. Tamaoki, M. Sasaki, M. Haniffa +16 more
2021Clinical Genetics23 citations
Semantic Scholar
De novo ARF3 variants cause neurodevelopmental disorder with brain abnormality.
M. Sakamoto, K. Sasaki, A. Sugie, Yohei Nitta +21 more
2021Human Molecular Genetics21 citations Open access
Semantic Scholar
A novel PAK1 variant causative of neurodevelopmental disorder with postnatal macrocephaly
S. Ohori, S. Mitsuhashi, Revital Ben-Haim, E. Heyman +3 more
2020Journal of Human Genetics20 citations
Semantic Scholar
Biallelic structural variations within FGF12 detected by long-read sequencing in epilepsy
S. Ohori, A. Miyauchi, H. Osaka, C. Lourenço +18 more
2023Life Science Alliance18 citations Open access
Semantic Scholar
Development and Structural Evaluation of N‐Alkylated trans‐2‐Phenylcyclopropylamine‐Based LSD1 Inhibitors
H. Niwa, S. Sato, N. Handa, T. Sengoku +2 more
2020ChemMedChem18 citations
Semantic Scholar
Structure of the human Bre1 complex bound to the nucleosome
Shuhei Onishi, Kotone Uchiyama, Ko Sato, Chikako Okada +6 more
2023bioRxiv16 citations Open access
Semantic Scholar
Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity
K. Nishio, R. Belle, T. Katoh, A. Kawamura +6 more
2018ChemBioChem16 citations Open access
Semantic Scholar
The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype
Gökhan Yigit, Ken Saida, D. Demarzo, N. Miyake +20 more
2019Human Mutation14 citations Open access
Semantic Scholar
Characterization and Structure of the Aquifex aeolicus Protein DUF752
A. Kitamura, M. Nishimoto, T. Sengoku, Rie Shibata +5 more
2012Journal of Biological Chemistry13 citations Open access
Semantic Scholar
Genetic and functional diversity of β-N-acetylgalactosamine-targeting glycosidases expanded by deep-sea metagenome analysis
Tomomi Sumida, Satoshi Hiraoka, K. Usui, Akihiro Ishiwata +6 more
2024Nature Communications12 citations Open access
Semantic Scholar
Crystal structure of the bifunctional tRNA modification enzyme MnmC from Escherichia coli
A. Kitamura, T. Sengoku, M. Nishimoto, S. Yokoyama +1 more
2011Protein Science11 citations Open access
Semantic Scholar
OTUD5 Variants Associated With X-Linked Intellectual Disability and Congenital Malformation
Ken Saida, T. Fukuda, D. Scott, T. Sengoku +14 more
2021Frontiers in Cell and Developmental Biology10 citations Open access
Semantic Scholar
Crystallization and preliminary X-ray analysis of the helicase domains of Vasa complexed with RNA and an ATP analogue.
T. Sengoku, O. Nureki, N. Dohmae, A. Nakamura +1 more
2004Acta Crystallographica Section D: Biological Crystallography5 citations
Semantic Scholar
Clinical and genetic spectrum of patients with IRF2BPL syndrome
Kazuhiro Iwama, Mitsuhiro Kato, Y. Uchiyama, M. Sakamoto +27 more
2025Journal of Human Genetics3 citations
Semantic Scholar
A SelB/EF-Tu/aIF2γ-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNACys
T. Yanagisawa, R. Ishii, Yasushi Hikida, R. Fukunaga +3 more
2015Journal of Structural and Functional Genomics3 citations Open access
Semantic Scholar
Characterization and structure of the Aquifex aeolicus protein DUF752: a bacterial tRNA-methyltransferase (MnmC2) functioning without the usually fused oxidase domain (MnmC1)
A. Kitamura, M. Nishimoto, T. Sengoku, Rie Shibata +5 more
20123 citations
Semantic Scholar
Germline-derived GNAS-Gsα variants associated with both gain-of-function and loss-of-function phenotypes.
A. Carcavilla, A. Pereda, M. Miyado, M. Fukami +12 more
2025European Journal of Endocrinology2 citations
Semantic Scholar
Genetic and functional diversity of β-N-acetylgalactosamine residue-targeting glycosidases expanded by deep-sea metagenome
T. Sumida, S. Hiraoka, K. Usui, A. Ishiwata +6 more
2023bioRxiv2 citations Open access
Semantic Scholar
SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53.
Zhanyun Tang, Wei-Yi Chen, Miho Shimada, U. Nguyen +7 more
2023Cell2 citations Open access
Semantic Scholar
LimF is a versatile prenyltransferase catalyzing histidine-C-geranylation on diverse nonnatural substrates
Yu-Chen Zhang, K. Hamada, D. T. Nguyen, Sumika Inoue +8 more
20211 citations Open access
Semantic Scholar
Crystal structure of the SelB-like elongation factor EF-Pyl from Methanosarcina mazei
T. Yanagisawa, R. Ishii, R. Fukunaga, T. Sengoku +2 more
20081 citations
Semantic Scholar
NSD2 E1099K mutant bound to nucleosome
T. Sengoku, K. Sato, T. Nishizawa, O. Nureki +1 more
20210 citations
Semantic Scholar
Author response for "Pathogenic variants in the SMN complex gene GEMIN5 cause cerebellar atrophy"
Ken Saida, J. Tamaoki, M. Sasaki, M. Haniffa +16 more
20210 citations Open access
Semantic Scholar
FXIIa-cMCoFx1 complex
T. Sengoku, Wenyu Liu, S. D. de Veer, Yen-Hua Huang +8 more
20210 citations
Semantic Scholar
Structural Basis for FXIIa Inhibition by a Peptide Foldamer Containing Cyclic β-Amino Acids
T. Sengoku
2021Nihon Kessho Gakkaishi0 citations Open access
Semantic Scholar
Human Coagulation Factor XIIa (FXIIa) bound with the macrocyclic peptide F3 containing two (1S,2S)-2-ACHC residues
T. Sengoku, T. Katoh, K. Hirata, H. Suga +1 more
20200 citations
Semantic Scholar
Relationship between spatial distribution of organic compounds and minerals in the Murchison meteorite
T. Sengoku, M. Hashiguchi, H. Naraoka
20190 citations
Semantic Scholar
Spotlights on our sister journals: Angew. Chem. Int. Ed. 26/2018.
M. Uzelac, R. Mulvey, Q. Lin, P. Wang +16 more
2018Angewandte Chemie0 citations
Semantic Scholar
EarP bound with dTDP-rhamnose (co-crystal)
T. Sengoku, S. Yokoyama, T. Yanagisawa
20180 citations
Semantic Scholar
EarP bound with dTDP-rhamnose (soaked)
T. Sengoku, S. Yokoyama, T. Yanagisawa
20180 citations
Semantic Scholar

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