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K. Saliba · SciRah

Researcher profile · Semantic Scholar

K. Saliba

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K. Saliba — researcher profile on SciRah

h-index: 35
Works: 83
Citations: 4,798

Most-cited papers

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
M. Reed, K. Saliba, Sonia R. Caruana, K. Kirk +1 more
2000Nature889 citations
Semantic Scholar
Coenzyme A biosynthesis: an antimicrobial drug target.
Christina Spry, K. Kirk, K. Saliba
2008FEMS Microbiology Reviews271 citations Open access
Semantic Scholar
Transport and Metabolism of the Essential Vitamin Pantothenic Acid in Human Erythrocytes Infected with the Malaria ParasitePlasmodium falciparum *
K. Saliba, Heather A. Horner, K. Kirk
1998Journal of Biological Chemistry215 citations Open access
Semantic Scholar
Membrane transport in the malaria-infected erythrocyte
Rowena E. Martin, K. Saliba, H. Staines, K. Kirk
2000199 citations
Semantic Scholar
Calothrixins A and B, novel pentacyclic metabolites from Calothrix cyanobacteria with potent activity against malaria parasites and human cancer cells
R. W. Rickards, J. Rothschild, A. Willis, Nola M. de Chazal +4 more
1999195 citations Open access
Semantic Scholar
pH Regulation in the Intracellular Malaria Parasite, Plasmodium falciparum
K. Saliba, K. Kirk
1999Journal of Biological Chemistry195 citations Open access
Semantic Scholar
The pH of the digestive vacuole of Plasmodium falciparum is not associated with chloroquine resistance
R. Hayward, K. Saliba, K. Kirk
2006Journal of Cell Science142 citations
Semantic Scholar
Acidification of the Malaria Parasite's Digestive Vacuole by a H+-ATPase and a H+-pyrophosphatase*
K. Saliba, Richard J. W. Allen, Stephanie Zissis, P. Bray +2 more
2003Journal of Biological Chemistry137 citations Open access
Semantic Scholar
Role for the plasmodium falciparum digestive vacuole in chloroquine resistance.
K. Saliba, Peter I. Folb, P. Smith
1998Biochemical Pharmacology124 citations
Semantic Scholar
Antiplasmodial Chalcones Inhibit Sorbitol-Induced Hemolysis of Plasmodium falciparum-Infected Erythrocytes
M. Go, Mei Liu, P. Wilairat, P. Rosenthal +2 more
2004Antimicrobial Agents and Chemotherapy112 citations Open access
Semantic Scholar
pfmdr1 mutations associated with chloroquine resistance incur a fitness cost in Plasmodium falciparum
R. Hayward, K. Saliba, K. Kirk
2005Molecular Microbiology109 citations Open access
Semantic Scholar
Electrophysiological studies of malaria parasite-infected erythrocytes: current status.
H. Staines, A. Alkhalil, Richard J. W. Allen, H. D. de Jonge +18 more
2007International Journal of Parasitology104 citations Open access
Semantic Scholar
Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite
K. Saliba, Rowena E. Martin, A. Bröer, Roselani I. Henry +7 more
2006Nature101 citations
Semantic Scholar
Analysis of Breath Specimens for Biomarkers of Plasmodium falciparum Infection
A. Berna, J. McCarthy, Rosa Wang, K. Saliba +4 more
2015Journal of Infectious Diseases95 citations Open access
Semantic Scholar
Pantothenamides Are Potent, On-Target Inhibitors of Plasmodium falciparum Growth When Serum Pantetheinase Is Inactivated
Christina Spry, Cristiano Macuamule, Zhiyang Lin, Kristopher G. Virga +3 more
2013PLoS ONE92 citations Open access
Semantic Scholar
H+-coupled Pantothenate Transport in the Intracellular Malaria Parasite*
K. Saliba, K. Kirk
2001Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Transport of lactate and pyruvate in the intraerythrocytic malaria parasite, Plasmodium falciparum.
J. L. Elliott, K. Saliba, Kiaran Kirk
2001Biochemical Journal80 citations Open access
Semantic Scholar
Targeting nutrient uptake mechanisms in Plasmodium.
K. Kirk, K. Saliba
2007Current Drug Targets68 citations
Semantic Scholar
Provitamin B5 (Pantothenol) Inhibits Growth of the Intraerythrocytic Malaria Parasite
K. Saliba, I. Ferru, K. Kirk
2005Antimicrobial Agents and Chemotherapy67 citations Open access
Semantic Scholar
Nutrient acquisition by intracellular apicomplexan parasites: staying in for dinner.
K. Saliba, Kiaran Kirk
2001International Journal of Parasitology63 citations
Semantic Scholar
Common dietary flavonoids inhibit the growth of the intraerythrocytic malaria parasite
Adele M. Lehane, K. Saliba
2008BMC Research Notes62 citations Open access
Semantic Scholar
The Inhibitory Effect of 2-Halo Derivatives of d-Glucose on Glycolysis and on the Proliferation of the Human Malaria Parasite Plasmodium falciparum
D. V. van Schalkwyk, W. Priebe, K. Saliba
2008Journal of Pharmacology and Experimental Therapeutics59 citations
Semantic Scholar
A verapamil-sensitive chloroquine-associated H+ leak from the digestive vacuole in chloroquine-resistant malaria parasites
Adele M. Lehane, R. Hayward, K. Saliba, K. Kirk
2008Journal of Cell Science57 citations Open access
Semantic Scholar
Chemical and genetic validation of thiamine utilization as an antimalarial drug target
X. Chan, C. Wrenger, Katharina Stahl, Bärbel Bergmann +3 more
2013Nature Communications55 citations Open access
Semantic Scholar
A Class of Pantothenic Acid Analogs Inhibits Plasmodium falciparum Pantothenate Kinase and Represses the Proliferation of Malaria Parasites
Christina Spry, C. Chai, K. Kirk, K. Saliba
2005Antimicrobial Agents and Chemotherapy54 citations Open access
Semantic Scholar
Choline uptake into the malaria parasite is energized by the membrane potential.
Adele M. Lehane, K. Saliba, Richard J. W. Allen, K. Kirk
2004Biochemical and Biophysical Research Communications - BBRC54 citations
Semantic Scholar
Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death.
D. V. van Schalkwyk, X. Chan, Paola Misiano, S. Gagliardi +2 more
2010Biochemical Pharmacology52 citations
Semantic Scholar
Transport of nucleosides across the Plasmodium falciparum parasite plasma membrane has characteristics of PfENT1
Megan J. Downie, K. Saliba, S. Howitt, S. Bröer +1 more
2006Molecular Microbiology50 citations Open access
Semantic Scholar
Inhibition of hexose transport and abrogation of pH homeostasis in the intraerythrocytic malaria parasite by an O‐3‐hexose derivative
K. Saliba, S. Krishna, K. Kirk
2004FEBS Letters49 citations
Semantic Scholar
Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activity.
M. de Villiers, Cristiano Macuamule, Christina Spry, Yoo-Min Hyun +2 more
2013ACS Medicinal Chemistry Letters48 citations Open access
Semantic Scholar
Pantothenate utilization by Plasmodium as a target for antimalarial chemotherapy.
Christina Spry, D. V. van Schalkwyk, E. Strauss, K. Saliba
2010Infectious Diseases - Drug Targets46 citations
Semantic Scholar
Distribution of acridine orange fluorescence in Plasmodium falciparum-infected erythrocytes and its implications for the evaluation of digestive vacuole pH.
P. Bray, K. Saliba, Jill Davies, D. Spiller +3 more
2002Molecular and biochemical parasitology (Print)41 citations
Semantic Scholar
Hexose transport in asexual stages of Plasmodium falciparum and kinetoplastidae.
Sanjeev Krishna, Charles J. Woodrow, Richard Burchmore, K. Saliba +1 more
2000Parasitology Today41 citations
Semantic Scholar
Purine nucleobase transport in the intraerythrocytic malaria parasite.
Megan J. Downie, K. Saliba, S. Bröer, S. Howitt +1 more
2008International Journal of Parasitology40 citations
Semantic Scholar
The Human Malaria Parasite Plasmodium falciparum Is Not Dependent on Host Coenzyme A Biosynthesis*
Christina Spry, K. Saliba
2009Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Transport properties of the host cell membrane.
Kiaran Kirk, H. Staines, Rowena E. Martin, K. Saliba
1999Novartis Foundation symposium35 citations
Semantic Scholar
Purine uptake in Plasmodium: transport versus metabolism.
K. Kirk, S. Howitt, S. Bröer, K. Saliba +1 more
2009Trends in Parasitology33 citations
Semantic Scholar
Clotrimazole inhibits the growth of Plasmodium falciparum in vitro.
K. Saliba, Kiaran Kirk
1998Transactions of the Royal Society of Tropical Medicine and Hygiene32 citations
Semantic Scholar
Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues
Erick T. Tjhin, Christina Spry, Alan L. Sewell, A. Hoegl +10 more
2017bioRxiv31 citations Open access
Semantic Scholar
Uptake of an antiplasmodial protease inhibitor into Plasmodium falciparum-infected human erythrocytes via a parasite-induced pathway.
K. Saliba, Kiaran Kirk
1998Molecular and biochemical parasitology (Print)31 citations
Semantic Scholar
Loss of pH Control in Plasmodium falciparum Parasites Subjected to Oxidative Stress
D. V. van Schalkwyk, K. Saliba, G. Biagini, P. Bray +1 more
2013PLoS ONE30 citations Open access
Semantic Scholar
Purification of functional Plasmodium falciparum tubulin allows for the identification of parasite-specific microtubule inhibitors
W. Hirst, Dominik Fachet, B. Kuropka, C. Weise +2 more
2021bioRxiv29 citations Open access
Semantic Scholar
Antiplasmodial Mode of Action of Pantothenamides: Pantothenate Kinase Serves as a Metabolic Activator Not as a Target.
M. de Villiers, Christina Spry, Cristiano Macuamule, L. Barnard +3 more
2017ACS Infectious Diseases29 citations
Semantic Scholar
A Pantetheinase-Resistant Pantothenamide with Potent, On-Target, and Selective Antiplasmodial Activity
Cristiano Macuamule, Erick T. Tjhin, C. E. Jana, L. Barnard +4 more
2015Antimicrobial Agents and Chemotherapy27 citations Open access
Semantic Scholar
Ulva additions alter soil biogeochemistry and negatively impact Spartina alterniflora growth.
E. Watson, C. Wigand, A. Oczkowski, K. Sundberg +4 more
201527 citations
Semantic Scholar
CJ-15,801, a fungal natural product, inhibits the intraerythrocytic stage of Plasmodium falciparum in vitro via an effect on pantothenic acid utilisation.
K. Saliba, K. Kirk
2005Molecular and biochemical parasitology (Print)27 citations
Semantic Scholar
Triazole Substitution of a Labile Amide Bond Stabilizes Pantothenamides and Improves Their Antiplasmodial Potency
Vanessa M. Howieson, Elisa Tran, A. Hoegl, Han Ling Fam +5 more
2016Antimicrobial Agents and Chemotherapy25 citations Open access
Semantic Scholar
Mutations in pfmdr1 Modulate the Sensitivity of Plasmodium falciparum to the Intrinsic Antiplasmodial Activity of Verapamil
R. Hayward, K. Saliba, K. Kirk
2005Antimicrobial Agents and Chemotherapy23 citations Open access
Semantic Scholar
Feedback Inhibition of Pantothenate Kinase Regulates Pantothenol Uptake by the Malaria Parasite*
Adele M. Lehane, R. Marchetti, Christina Spry, D. V. van Schalkwyk +3 more
2007Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Stereochemical modification of geminal dialkyl substituents on pantothenamides alters antimicrobial activity.
A. Hoegl, H. Darabi, Elisa Tran, E. Awuah +4 more
2014Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar

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K. Kirk×27
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K. Kirk — researcher profile on SciRah
Christina Spry×9
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E. Strauss×6
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Kiaran Kirk×6
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D. V. van Schalkwyk

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