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L. Gouw · SciRah

Researcher profile · Semantic Scholar

L. Gouw

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L. Gouw — researcher profile on SciRah

h-index: 11
Works: 21
Citations: 884

Most-cited papers

Retinal degeneration characterizes a spinocerebellar ataxia mapping to chromosome 3p
L. Gouw, C. Kaplan, J. Haines, K. Digre +5 more
1995Nature Genetics152 citations
Semantic Scholar
Autosomal dominant cerebellar ataxia with retinal degeneration
L. Gouw, K. Digre, C. Harris, J. Haines +1 more
1994Neurology135 citations
Semantic Scholar
Sodium channel mutations in paramyotonia congenita and hyperkalemic periodic paralysis
Louis J. Ptáček, L. Gouw, H. Kwiecinski, P. McManis +6 more
1993Annals of Neurology127 citations
Semantic Scholar
Analysis of the dynamic mutation in the SCA7 gene shows marked parental effects on CAG repeat transmission.
L. Gouw, M. Castañeda, C. McKenna, Kathleen B. Digre +10 more
1998Human Molecular Genetics112 citations Open access
Semantic Scholar
Proteolytic Cleavage of Ataxin-7 by Caspase-7 Modulates Cellular Toxicity and Transcriptional Dysregulation*
Jessica E. Young, L. Gouw, Stephanie S. Propp, B. Sopher +11 more
2007Journal of Biological Chemistry96 citations Open access
Semantic Scholar
Is There a Predisposition Gene for Ewing's Sarcoma?
R. Randall, S. Lessnick, K. B. Jones, L. Gouw +3 more
2010Journal of Oncology53 citations Open access
Semantic Scholar
Exploiting antitumor immunity to overcome relapse and improve remission duration
Lei L. Chen, Xinjian Chen, Haesun Choi, Hong-Xun Sang +25 more
2011Cancer Immunology and Immunotherapy50 citations Open access
Semantic Scholar
Investigational Aurora A kinase inhibitor alisertib (MLN8237) as an enteric-coated tablet formulation in non-hematologic malignancies: Phase 1 dose-escalation study
G. Falchook, R. Kurzrock, L. Gouw, D. Hong +5 more
2014Investigational new drugs44 citations Open access
Semantic Scholar
Expression of the Rho‐family GTPase gene RHOF in lymphocyte subsets and malignant lymphomas
L. Gouw, N. Reading, Stephen D. Jenson, M. Lim +1 more
2005British Journal of Haematology41 citations
Semantic Scholar
Phase Ib study of RG7112 with doxorubicin (D) in advanced soft tissue sarcoma (ASTS).
S. Chawla, J. Blay, A. Italiano, M. Gutierrez +13 more
201326 citations
Semantic Scholar
Phase II study of amrubicin (SM-5887), a synthetic 9-aminoanthracycline, as first line treatment in patients with metastatic or unresectable soft tissue sarcoma: durable response in myxoid liposarcoma with TLS-CHOP translocation
Sumati V. Gupta, L. Gouw, J. Wright, S. Chawla +4 more
2016Investigational new drugs17 citations
Semantic Scholar
Combining targeted therapy with immunotherapy (interferon-α)
Lei L. Chen, L. Gouw, M. Sabripour, W. Hwu +1 more
2012Oncoimmunology9 citations Open access
Semantic Scholar
Results of the randomized phase III trial of trabectedin (T) versus doxorubicin-based chemotherapy (DXCT) as first-line therapy in patients (pts) with translocation-related sarcoma (TRS).
A. Hendifar, S. Chawla, M. Leahy, A. Italiano +14 more
20136 citations
Semantic Scholar
Phase I dose-escalation study of the investigational Aurora A kinase (AAK) inhibitor MLN8237 as an enteric-coated tablet (ECT) formulation in patients with nonhematologic malignancies.
Sunil Sharma, R. Kurzrock, L. Gouw, D. Hong +5 more
2011Journal of Clinical Oncology6 citations
Semantic Scholar
SCF-KIT signaling induces endothelin-3 synthesis and secretion: Thereby activates and regulates endothelin-B-receptor for generating temporally- and spatially-precise nitric oxide to modulate SCF- and or KIT-expressing cell functions
Lei L. Chen, Jing Zhu, Jonathan A. Schumacher, Chong-Juan Wei +14 more
2017PLoS ONE3 citations Open access
Semantic Scholar
Combination of targeted therapy (imatinib) with immunotherapy (peginterferon {alpha}-2b) to overcome drug resistance and tumor stem cells in gastrointestinal stromal tumors (GIST).
Lei L. Chen, Xinjian Chen, L. Gouw, R. Andtbacka +6 more
20103 citations
Semantic Scholar
The effect of immunotoxins directed against CD80 and CD86 on primary T-cell alloresponses.
H. G. Often, W. Vooijs, L. Gouw, M. D. de Boer +1 more
1998Tissue Antigens3 citations
Semantic Scholar
Sarcoma Immunotherapy
L. Gouw, Kevin B. Jones, Sunil Sharma, R. Randall
2011Cancers1 citations Open access
Semantic Scholar
A phase II trial of novel anthracycline amrubicin in advanced soft tissue sarcoma.
L. Gouw, R. Randall, Kevin B. Jones, S. Chawla +1 more
20130 citations
Semantic Scholar
RhoF GTPase Transcription Is Upregulated in Germinal Center B-Cells, Shows Altered Expression in Malignant B-Cells, and Interacts with the ATM Pathway.
L. Gouw, N. Reading, David K. Crockett, P. Szankasi +2 more
20050 citations
Semantic Scholar
AUTOSOMAL DOMINANT SPINOCEREBELLAR ATAXIA: Olivopontocerebellar Atrophy Locus Heterogeneity Reflects Phenotypic Variation
L. Gouw, K. Digre, C. Harris, N. Mamalis +1 more
19930 citations
Semantic Scholar

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